Details of the Target

General Information of Target

Target ID LDTP07881
Target Name Inactive ubiquitin carboxyl-terminal hydrolase 54 (USP54)
Gene Name USP54
Gene ID 159195
Synonyms
C10orf29; Inactive ubiquitin carboxyl-terminal hydrolase 54; Inactive ubiquitin-specific peptidase 54
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS
FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD
AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ
MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM
NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG
KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ
DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG
TVIYNVENDSMSQSSRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYH
SEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQP
DKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYT
QLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMES
GYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTAS
MGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMD
LDELQNQGRSDGFERSLQEAESVFEESLHLEQKGDCAAALALCNEAISKLRLALHGASCS
THSRALVDKKLQISIRKARSLQDRMQQQQSPQQPSQPSACLPTQAGTLSQPTSEQPIPLQ
VLLSQEAQLESGMDTEFGASSFFHSPASCHESHSSLSPESSAPQHSSPSRSALKLLTSVE
VDNIEPSAFHRQGLPKAPGWTEKNSHHSWEPLDAPEGKLQGSRCDNSSCSKLPPQEGRGI
AQEQLFQEKKDPANPSPVMPGIATSERGDEHSLGCSPSNSSAQPSLPLYRTCHPIMPVAS
SFVLHCPDPVQKTNQCLQGQSLKTSLTLKVDRGSEETYRPEFPSTKGLVRSLAEQFQRMQ
GVSMRDSTGFKDRSLSGSLRKNSSPSDSKPPFSQGQEKGHWPWAKQQSSLEGGDRPLSWE
ESTEHSSLALNSGLPNGETSSGGQPRLAEPDIYQEKLSQVRDVRSKDLGSSTDLGTSLPL
DSWVNITRFCDSQLKHGAPRPGMKSSPHDSHTCVTYPERNHILLHPHWNQDTEQETSELE
SLYQASLQASQAGCSGWGQQDTAWHPLSQTGSADGMGRRLHSAHDPGLSKTSTAEMEHGL
HEARTVRTSQATPCRGLSRECGEDEQYSAENLRRISRSLSGTVVSEREEAPVSSHSFDSS
NVRKPLETGHRCSSSSSLPVIHDPSVFLLGPQLYLPQPQFLSPDVLMPTMAGEPNRLPGT
SRSVQQFLAMCDRGETSQGAKYTGRTLNYQSLPHRSRTDNSWAPWSETNQHIGTRFLTTP
GCNPQLTYTATLPERSKGLQVPHTQSWSDLFHSPSHPPIVHPVYPPSSSLHVPLRSAWNS
DPVPGSRTPGPRRVDMPPDDDWRQSSYASHSGHRRTVGEGFLFVLSDAPRREQIRARVLQ
HSQW
Target Bioclass
Enzyme
Family
Peptidase C19 family
Function Has no peptidase activity.
Uniprot ID
Q70EL1
Ensemble ID
ENST00000339859.8
HGNC ID
HGNC:23513

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA SNV: p.E1377D .
DOTC24510 SNV: p.F613L .
DU145 SNV: p.L1419I .
G402 SNV: p.S949N .
GB1 SNV: p.E162K .
HDQP1 SNV: p.L602V .
HT Insertion: p.P544TfsTer3 .
JURKAT SNV: p.A157V .
MCC13 SNV: p.R5K; p.S566F .
MFE319 SNV: p.K620N; p.I1302T .
NCIH358 SNV: p.S665N .
OSRC2 SNV: p.R1138K .
SKMEL28 SNV: p.P1631L .
SNGM SNV: p.G439Ter .
SW756 SNV: p.E1493K .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
NAIA_5
 Probe Info  		C839(0.35)  LDD2227  [2]
AHL-Pu-1
 Probe Info  		C124(10.55)  LDD0170  [3]
Acrolein
 Probe Info  		N.A.  LDD0227  [4]
DBIA
 Probe Info  		C1004(1.01); C1009(1.01); C145(0.95); C150(0.95)  LDD0078  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [6]
IPM
 Probe Info  		N.A.  LDD0147  [7]
TFBX
 Probe Info  		N.A.  LDD0148  [7]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [8]
AOyne
 Probe Info  		14.40  LDD0443  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C124(10.55)  LDD0170  [3]
 LDCM0026  4SU-RNA+native RNA DM93 C88(2.69); C597(2.55); C124(2.38); C1086(2.60)  LDD0171  [3]
 LDCM0214  AC1 HCT 116 C1394(0.60); C145(0.69); C150(0.69)  LDD0531  [5]
 LDCM0215  AC10 HCT 116 C1004(1.04); C1009(1.04); C1394(0.63); C145(0.68)  LDD0532  [5]
 LDCM0216  AC100 HCT 116 C1004(1.25); C1009(1.25); C145(1.08); C150(1.08)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C1004(1.47); C1009(1.47); C145(0.87); C150(0.87)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C1004(1.18); C1009(1.18); C145(0.87); C150(0.87)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C1004(1.52); C1009(1.52); C145(0.84); C150(0.84)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C1004(0.88); C1009(0.88); C145(0.92); C150(0.92)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C1004(1.53); C1009(1.53); C145(0.95); C150(0.95)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C1004(1.77); C1009(1.77); C145(0.86); C150(0.86)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C1004(1.48); C1009(1.48); C145(0.87); C150(0.87)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C1004(1.49); C1009(1.49); C145(1.01); C150(1.01)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C1004(1.25); C1009(1.25); C145(0.94); C150(0.94)  LDD0542  [5]
 LDCM0226  AC11 HCT 116 C1004(1.21); C1009(1.21); C1394(0.73); C145(0.79)  LDD0543  [5]
 LDCM0227  AC110 HCT 116 C1004(1.44); C1009(1.44); C145(0.92); C150(0.92)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C1004(1.49); C1009(1.49); C145(0.91); C150(0.91)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C1004(1.38); C1009(1.38); C145(0.81); C150(0.81)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C145(0.85); C150(0.85)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C145(0.76); C150(0.76)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C145(0.85); C150(0.85)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C145(0.81); C150(0.81)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C145(0.96); C150(0.96)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C145(0.88); C150(0.88)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C145(0.89); C150(0.89)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C1004(0.98); C1009(0.98); C1394(0.72); C145(0.74)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C145(0.78); C150(0.78)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C145(0.93); C150(0.93)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C145(0.93); C150(0.93)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C145(0.89); C150(0.89)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C145(0.92); C150(0.92)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C145(0.87); C150(0.87)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C145(0.86); C150(0.86)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C145(0.96); C150(0.96)  LDD0562  [5]
 LDCM0246  AC128 HCT 116 C145(1.55); C150(1.55)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C145(1.26); C150(1.26)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C145(1.43); C150(1.43)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C145(1.23); C150(1.23)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C145(1.38); C150(1.38)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C145(1.39); C150(1.39)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C145(1.48); C150(1.48)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C145(1.41); C150(1.41)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C145(1.31); C150(1.31)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C145(1.32); C150(1.32)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C145(1.56); C150(1.56)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C145(1.47); C150(1.47)  LDD0575  [5]
 LDCM0259  AC14 HCT 116 C1004(1.07); C1009(1.07); C1394(0.58); C145(0.95)  LDD0576  [5]
 LDCM0260  AC140 HCT 116 C145(1.49); C150(1.49)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C145(1.57); C150(1.57)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C145(1.44); C150(1.44)  LDD0579  [5]
 LDCM0263  AC143 HEK-293T C145(1.00); C150(1.00); C229(0.90)  LDD0861  [5]
 LDCM0264  AC144 HEK-293T C145(1.04); C150(1.04); C229(1.15)  LDD0862  [5]
 LDCM0265  AC145 HEK-293T C145(1.06); C150(1.06); C229(1.58)  LDD0863  [5]
 LDCM0266  AC146 HEK-293T C145(0.93); C150(0.93); C229(1.00)  LDD0864  [5]
 LDCM0267  AC147 HEK-293T C145(1.25); C150(1.25); C229(1.49)  LDD0865  [5]
 LDCM0268  AC148 HEK-293T C145(1.42); C150(1.42); C229(2.09)  LDD0866  [5]
 LDCM0269  AC149 HEK-293T C145(1.18); C150(1.18); C229(0.90)  LDD0867  [5]
 LDCM0270  AC15 HCT 116 C1394(0.76); C145(0.78); C150(0.78); C1004(0.87)  LDD0587  [5]
 LDCM0271  AC150 HEK-293T C145(1.18); C150(1.18); C229(1.33)  LDD0869  [5]
 LDCM0272  AC151 HEK-293T C145(1.13); C150(1.13); C229(1.40)  LDD0870  [5]
 LDCM0273  AC152 HEK-293T C145(1.15); C150(1.15); C229(0.97)  LDD0871  [5]
 LDCM0274  AC153 HEK-293T C145(1.21); C150(1.21); C229(1.34)  LDD0872  [5]
 LDCM0621  AC154 HEK-293T C145(1.05); C150(1.05); C229(1.25)  LDD2162  [5]
 LDCM0622  AC155 HEK-293T C145(0.92); C150(0.92); C229(0.77)  LDD2163  [5]
 LDCM0623  AC156 HEK-293T C145(1.14); C150(1.14); C229(1.22)  LDD2164  [5]
 LDCM0624  AC157 HEK-293T C145(1.56); C150(1.56); C229(1.49)  LDD2165  [5]
 LDCM0276  AC17 HCT 116 C225(1.11); C229(1.11)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C225(0.98); C229(0.98)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C225(1.07); C229(1.07)  LDD0595  [5]
 LDCM0279  AC2 HCT 116 C145(0.80); C150(0.80); C1394(0.90)  LDD0596  [5]
 LDCM0280  AC20 HCT 116 C225(0.91); C229(0.91)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C225(1.05); C229(1.05)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C225(1.20); C229(1.20)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C225(0.92); C229(0.92)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C225(1.08); C229(1.08)  LDD0601  [5]
 LDCM0285  AC25 HCT 116 C1004(0.84); C1009(0.84); C225(1.12); C229(1.12)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C1004(1.04); C1009(1.04); C145(1.10); C150(1.10)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C145(1.04); C150(1.04); C225(1.14); C229(1.14)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C145(1.06); C150(1.06); C1004(1.32); C1009(1.32)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C145(1.04); C150(1.04); C225(1.19); C229(1.19)  LDD0606  [5]
 LDCM0290  AC3 HCT 116 C1394(0.76); C145(0.79); C150(0.79)  LDD0607  [5]
 LDCM0291  AC30 HCT 116 C145(1.00); C150(1.00); C225(1.01); C229(1.01)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C145(0.97); C150(0.97); C225(1.07); C229(1.07)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C145(0.89); C150(0.89); C225(1.06); C229(1.06)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C145(0.87); C150(0.87); C1004(1.03); C1009(1.03)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C145(0.87); C150(0.87); C225(1.02); C229(1.02)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C145(0.88); C150(0.88); C229(1.08); C225(1.12)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C145(1.01); C150(1.01); C225(1.07); C229(1.17)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C145(0.94); C150(0.94); C225(1.11); C229(1.57)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C145(0.78); C150(0.78); C229(0.89); C225(0.91)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C145(0.82); C150(0.82); C229(0.92); C225(0.98)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C145(0.73); C150(0.73); C1394(1.13)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C145(0.98); C150(0.98); C225(1.05); C229(1.48)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C145(0.84); C150(0.84); C225(1.09); C229(1.18)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C145(0.74); C150(0.74); C225(1.22); C229(1.43)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C225(1.03); C145(1.25); C150(1.25); C229(1.32)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C145(0.84); C150(0.84); C225(1.05); C229(1.16)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C145(0.88); C150(0.88); C225(1.14); C229(1.23)  LDD0624  [5]
 LDCM0308  AC46 HCT 116 C145(0.91); C150(0.91)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C145(0.90); C150(0.90)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C145(0.88); C150(0.88)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C145(0.99); C150(0.99)  LDD0628  [5]
 LDCM0312  AC5 HCT 116 C145(0.69); C150(0.69); C1394(0.79)  LDD0629  [5]
 LDCM0313  AC50 HCT 116 C145(0.99); C150(0.99)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C145(0.74); C150(0.74)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C145(0.86); C150(0.86)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C145(1.25); C150(1.25)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C145(0.88); C150(0.88)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C145(0.88); C150(0.88)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C145(0.82); C150(0.82)  LDD0636  [5]
 LDCM0320  AC57 HCT 116 C145(1.03); C150(1.03)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C145(1.03); C150(1.03)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C145(1.10); C150(1.10)  LDD0639  [5]
 LDCM0323  AC6 HCT 116 C1394(0.72); C145(0.88); C150(0.88); C225(1.05)  LDD0640  [5]
 LDCM0324  AC60 HCT 116 C145(1.12); C150(1.12)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C145(1.15); C150(1.15)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C145(0.95); C150(0.95)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C145(1.02); C150(1.02)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C145(0.86); C150(0.86)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C145(0.98); C150(0.98)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C145(1.29); C150(1.29)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C145(0.89); C150(0.89)  LDD0648  [5]
 LDCM0332  AC68 HCT 116 C145(0.67); C150(0.67); C1004(0.76); C1009(0.76)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C1394(0.81); C145(0.91); C150(0.91); C1004(1.00)  LDD0650  [5]
 LDCM0334  AC7 HCT 116 C1394(0.63); C145(0.87); C150(0.87); C1004(0.93)  LDD0651  [5]
 LDCM0335  AC70 HCT 116 C145(0.76); C150(0.76); C1394(0.84); C1004(0.99)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C1004(0.60); C1009(0.60); C145(0.84); C150(0.84)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C145(0.84); C150(0.84); C1394(1.41); C1004(1.48)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C145(0.75); C150(0.75); C1394(0.93); C1004(2.52)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C145(0.79); C150(0.79); C1394(0.86); C1004(1.21)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C145(0.77); C150(0.77); C1394(1.45); C1004(1.93)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C145(0.72); C150(0.72); C1004(1.09); C1009(1.09)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C145(0.77); C150(0.77); C1394(0.98); C1004(1.19)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C145(0.80); C150(0.80); C1394(0.97); C1004(1.54)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C145(0.81); C150(0.81); C1004(0.82); C1009(0.82)  LDD0661  [5]
 LDCM0345  AC8 HCT 116 C1394(0.68); C145(0.95); C150(0.95); C1004(0.99)  LDD0662  [5]
 LDCM0346  AC80 HCT 116 C145(0.90); C150(0.90); C1394(0.92); C1004(1.13)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C145(0.65); C150(0.65); C1394(0.73); C1004(0.99)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C145(0.84); C150(0.84); C1394(0.92); C1004(1.84)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C145(1.04); C150(1.04)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C145(0.96); C150(0.96)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C145(1.03); C150(1.03)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C145(1.29); C150(1.29)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C145(1.26); C150(1.26)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C145(1.09); C150(1.09)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C145(1.23); C150(1.23)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C145(1.04); C150(1.04)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C145(1.16); C150(1.16)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C145(1.01); C150(1.01)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C145(0.99); C150(0.99)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C145(1.35); C150(1.35)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C145(1.18); C150(1.18)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C145(1.14); C150(1.14)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C145(1.10); C150(1.10)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C225(0.72); C229(0.72); C145(0.90); C150(0.90)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C225(0.57); C229(0.57); C145(0.89); C150(0.89)  LDD0683  [5]
 LDCM0248  AKOS034007472 HCT 116 C1004(1.07); C1009(1.07); C1394(0.66); C145(0.75)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C145(0.73); C150(0.73); C1394(0.78); C225(1.11)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C145(0.69); C150(0.69); C1394(0.69); C1004(0.89)  LDD0592  [5]
 LDCM0156  Aniline NCI-H1299 13.97  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C1004(1.01); C1009(1.01); C145(0.95); C150(0.95)  LDD0078  [5]
 LDCM0632  CL-Sc Hep-G2 C839(0.35)  LDD2227  [2]
 LDCM0367  CL1 HCT 116 C145(1.17); C150(1.17)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C145(1.21); C150(1.21)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C145(0.66); C150(0.66); C1394(0.70)  LDD0686  [5]
 LDCM0370  CL101 HCT 116 C1394(0.58); C145(0.84); C150(0.84); C225(1.00)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C1394(0.67); C145(0.68); C150(0.68); C1004(1.17)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C1394(0.64); C145(0.84); C150(0.84); C1004(0.98)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C1394(0.70); C145(0.76); C150(0.76); C225(0.98)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C225(0.87); C229(0.87)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C225(1.04); C229(1.04)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C225(1.13); C229(1.13)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C225(1.02); C229(1.02)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C225(0.97); C229(0.97)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C145(1.70); C150(1.70)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C225(1.14); C229(1.14)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C225(0.92); C229(0.92)  LDD0698  [5]
 LDCM0382  CL112 HCT 116 C225(0.95); C229(0.95); C1004(0.99); C1009(0.99)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C225(0.90); C229(0.90); C145(0.97); C150(0.97)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C225(0.88); C229(0.88); C145(0.90); C150(0.90)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C145(0.85); C150(0.85); C225(0.97); C229(0.97)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C145(0.79); C150(0.79); C1004(0.99); C1009(0.99)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C145(0.78); C150(0.78); C225(0.90); C229(1.37)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C145(0.87); C150(0.87); C229(0.93); C225(1.08)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C145(0.89); C150(0.89); C225(1.10); C229(1.14)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C145(1.06); C150(1.06)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C145(0.87); C150(0.87); C225(1.07); C229(1.24)  LDD0708  [5]
 LDCM0392  CL121 HCT 116 C145(1.02); C150(1.02)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C145(0.92); C150(0.92)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C145(1.18); C150(1.18)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C145(0.89); C150(0.89)  LDD0712  [5]
 LDCM0396  CL125 HCT 116 C145(1.17); C150(1.17)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C145(1.22); C150(1.22)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C145(1.32); C150(1.32)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C145(1.03); C150(1.03)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C145(0.99); C150(0.99)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C145(1.08); C150(1.08)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C145(1.24); C150(1.24)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C225(0.87); C229(0.87); C1004(1.07); C1009(1.07)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C225(0.64); C229(0.64); C1004(0.87); C1009(0.87)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C225(0.71); C229(0.71); C1004(0.84); C1009(0.84)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C225(0.83); C229(0.83); C1004(0.90); C1009(0.90)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C145(1.17); C150(1.17)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C1004(0.87); C1009(0.87); C225(0.88); C229(0.88)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C1004(0.83); C1009(0.83); C145(0.89); C150(0.89)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C1004(0.88); C1009(0.88); C225(0.90); C229(0.90)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C225(0.73); C229(0.73); C1004(0.93); C1009(0.93)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C1004(1.10); C1009(1.10); C1394(2.17); C145(0.94)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C1004(1.06); C1009(1.06); C1394(2.15); C145(0.89)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C1004(0.93); C1009(0.93); C1394(1.68); C145(0.94)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C1004(1.10); C1009(1.10); C1394(1.88); C145(0.89)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C1004(1.03); C1009(1.03); C1394(1.95); C145(0.97)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C1004(1.03); C1009(1.03); C1394(1.40); C145(1.01)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C145(1.25); C150(1.25)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C1004(1.05); C1009(1.05); C1394(2.05); C145(0.96)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C145(1.04); C150(1.04); C225(0.76); C229(0.76)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C145(1.01); C150(1.01); C225(0.94); C229(0.94)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C145(0.88); C150(0.88); C225(1.14); C229(1.14)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C145(1.03); C150(1.03); C225(1.08); C229(1.08)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C145(0.95); C150(0.95); C225(1.75); C229(1.75)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C145(0.82); C150(0.82); C225(1.33); C229(1.33)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C145(0.85); C150(0.85); C225(1.68); C229(1.68)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C145(0.87); C150(0.87); C225(1.03); C229(1.03)  LDD0745  [5]
 LDCM0429  CL4 HCT 116 C145(1.21); C150(1.21)  LDD0746  [5]
 LDCM0430  CL40 HCT 116 C145(0.87); C150(0.87); C225(0.97); C229(0.97)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C145(1.03); C150(1.03); C225(2.44); C229(2.44)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C145(0.85); C150(0.85); C225(1.28); C229(1.28)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C145(0.93); C150(0.93); C225(1.44); C229(1.44)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C145(0.86); C150(0.86); C225(1.17); C229(1.17)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C145(0.77); C150(0.77); C225(1.35); C229(1.35)  LDD0752  [5]
 LDCM0436  CL46 HCT 116 C1004(0.87); C1009(0.87); C1394(0.78); C145(0.87)  LDD0753  [5]
 LDCM0437  CL47 HCT 116 C1004(0.74); C1009(0.74); C1394(1.07); C145(0.92)  LDD0754  [5]
 LDCM0438  CL48 HCT 116 C1004(0.82); C1009(0.82); C1394(1.08); C145(0.79)  LDD0755  [5]
 LDCM0439  CL49 HCT 116 C1004(0.86); C1009(0.86); C1394(0.87); C145(1.03)  LDD0756  [5]
 LDCM0440  CL5 HCT 116 C145(1.07); C150(1.07)  LDD0757  [5]
 LDCM0441  CL50 HCT 116 C1004(0.80); C1009(0.80); C1394(0.94); C145(0.86)  LDD0758  [5]
 LDCM0442  CL51 HCT 116 C1004(0.84); C1009(0.84); C1394(1.10); C145(0.90)  LDD0759  [5]
 LDCM0443  CL52 HCT 116 C1004(1.16); C1009(1.16); C1394(0.87); C145(0.86)  LDD0760  [5]
 LDCM0444  CL53 HCT 116 C1004(1.00); C1009(1.00); C1394(0.70); C145(0.96)  LDD0761  [5]
 LDCM0445  CL54 HCT 116 C1004(1.23); C1009(1.23); C1394(1.02); C145(0.81)  LDD0762  [5]
 LDCM0446  CL55 HCT 116 C1004(0.98); C1009(0.98); C1394(1.01); C145(0.82)  LDD0763  [5]
 LDCM0447  CL56 HCT 116 C1004(0.79); C1009(0.79); C1394(0.92); C145(0.84)  LDD0764  [5]
 LDCM0448  CL57 HCT 116 C1004(0.89); C1009(0.89); C1394(1.08); C145(0.83)  LDD0765  [5]
 LDCM0449  CL58 HCT 116 C1004(1.01); C1009(1.01); C1394(1.18); C145(0.88)  LDD0766  [5]
 LDCM0450  CL59 HCT 116 C1004(0.95); C1009(0.95); C1394(0.83); C145(0.93)  LDD0767  [5]
 LDCM0451  CL6 HCT 116 C145(0.98); C150(0.98)  LDD0768  [5]
 LDCM0452  CL60 HCT 116 C1004(0.94); C1009(0.94); C1394(1.15); C145(0.76)  LDD0769  [5]
 LDCM0453  CL61 HCT 116 C145(1.11); C150(1.11); C225(1.28); C229(1.28)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C145(1.18); C150(1.18); C225(1.15); C229(1.15)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C145(0.86); C150(0.86); C225(1.23); C229(1.23)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C145(1.13); C150(1.13); C225(1.17); C229(1.17)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C145(1.16); C150(1.16); C225(1.31); C229(1.31)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C145(1.02); C150(1.02); C225(1.06); C229(1.06)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C145(0.92); C150(0.92); C225(1.39); C229(1.39)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C145(0.88); C150(0.88); C225(1.14); C229(1.14)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C145(1.04); C150(1.04); C225(1.09); C229(1.09)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C145(1.21); C150(1.21)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C145(1.08); C150(1.08); C225(1.14); C229(1.14)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C145(0.94); C150(0.94); C225(1.05); C229(1.05)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C145(0.92); C150(0.92); C225(1.20); C229(1.20)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C145(0.86); C150(0.86); C225(1.19); C229(1.19)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C145(0.96); C150(0.96); C225(1.11); C229(1.11)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C145(1.04); C150(1.04); C225(1.17); C229(1.17)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C145(0.95); C150(0.95); C225(1.08); C229(1.08)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C145(0.95); C150(0.95); C225(1.03); C229(1.03)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C145(0.90); C150(0.90); C225(1.58); C229(1.58)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C145(1.05); C150(1.05)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C145(0.90); C150(0.90); C225(1.62); C229(1.62)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C145(0.99); C150(0.99); C225(1.35); C229(1.35)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C145(0.87); C150(0.87); C225(1.12); C229(1.12)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C145(0.98); C150(0.98); C225(1.34); C229(1.34)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C145(0.83); C150(0.83); C225(1.39); C229(1.39)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C145(0.94); C150(0.94); C225(1.36); C229(1.36)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C145(0.85); C150(0.85); C225(1.16); C229(1.16)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C145(0.85); C150(0.85); C225(1.58); C229(1.58)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C145(0.84); C150(0.84); C225(1.69); C229(1.69)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C145(0.83); C150(0.83); C225(1.35); C229(1.35)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C145(1.19); C150(1.19)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C145(1.07); C150(1.07); C225(1.28); C229(1.28)  LDD0802  [5]
 LDCM0486  CL91 HCT 116 C1394(1.10); C145(1.01); C150(1.01)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C1394(1.16); C145(1.01); C150(1.01)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C1394(0.99); C145(1.06); C150(1.06)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C1394(0.75); C145(0.95); C150(0.95)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C1394(1.55); C145(0.86); C150(0.86)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C1394(1.37); C145(0.90); C150(0.90)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C1394(1.20); C145(0.77); C150(0.77)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C1394(0.94); C145(0.76); C150(0.76)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C1394(0.88); C145(0.66); C150(0.66)  LDD0811  [5]
 LDCM0495  E2913 HEK-293T C1562(1.14); C1511(0.94); C1270(0.97)  LDD1698  [10]
 LDCM0468  Fragment33 HCT 116 C145(0.82); C150(0.82); C225(1.62); C229(1.62)  LDD0785  [5]
 LDCM0427  Fragment51 HCT 116 C145(1.01); C150(1.01); C225(1.87); C229(1.87)  LDD0744  [5]
 LDCM0022  KB02 HCT 116 C69(3.17); C77(3.17); C74(3.17); C145(2.24)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C69(7.27); C77(7.27); C74(7.27); C145(2.53)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C69(2.22); C77(2.22); C74(2.22); C145(1.82)  LDD0082  [5]
 LDCM0109  NEM HeLa N.A.  LDD0227  [4]
 LDCM0021  THZ1 HCT 116 C1394(1.34); C145(1.20); C150(1.20)  LDD2173  [5]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 17 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
Cell division cycle protein 23 homolog (CDC23) APC8/CDC23 family Q9UJX2
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C) Archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family O15160
Histone-lysine N-methyltransferase SMYD1 (SMYD1) Class V-like SAM-binding methyltransferase superfamily Q8NB12
Putative histone-lysine N-methyltransferase PRDM6 (PRDM6) Class V-like SAM-binding methyltransferase superfamily Q9NQX0
Probable E3 ubiquitin-protein ligase DTX2 (DTX2) Deltex family Q86UW9
Uridine diphosphate glucose pyrophosphatase NUDT22 (NUDT22) Nudix hydrolase family Q9BRQ3
Ubiquitin carboxyl-terminal hydrolase 2 (USP2) Peptidase C19 family O75604
Testis-specific serine/threonine-protein kinase 3 (TSSK3) CAMK Ser/Thr protein kinase family Q96PN8
Serine/threonine-protein kinase 16 (STK16) Ser/Thr protein kinase family O75716
Tensin-2 (TNS2) PTEN phosphatase protein family Q63HR2
Terminal nucleotidyltransferase 5B (TENT5B) TENT family Q96A09
85/88 kDa calcium-independent phospholipase A2 (PLA2G6) . O60733
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
F-box only protein 17 (FBXO17) . Q96EF6
Rho-related BTB domain-containing protein 3 (RHOBTB3) . O94955
RING finger protein 208 (RNF208) . Q9H0X6
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Exocyst complex component 8 (EXOC8) EXO84 family Q8IYI6
Small ribosomal subunit protein RACK1 (RACK1) WD repeat G protein beta family P63244
Transcription factor
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C8 (HOXC8) Antp homeobox family P31273
Transcription factor AP-2-delta (TFAP2D) AP-2 family Q7Z6R9
Doublesex- and mab-3-related transcription factor 3 (DMRT3) DMRT family Q9NQL9
Hepatocyte nuclear factor 1-beta (HNF1B) HNF1 homeobox family P35680
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
Homeobox protein OTX1 (OTX1) Paired homeobox family P32242
PHD finger protein 1 (PHF1) Polycomblike family O43189
Chorion-specific transcription factor GCMb (GCM2) . O75603
Class E basic helix-loop-helix protein 40 (BHLHE40) . O14503
Homeobox protein VENTX (VENTX) . O95231
T-box transcription factor TBX6 (TBX6) . O95947
Transcriptional regulator QRICH1 (QRICH1) . Q2TAL8
Other
Click To Hide/Show 34 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-1 (ATXN1) ATXN1 family P54253
Ataxin-1-like (ATXN1L) ATXN1 family P0C7T5
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Docking protein 6 (DOK6) DOK family, Type B subfamily Q6PKX4
Eukaryotic translation initiation factor 4E type 2 (EIF4E2) Eukaryotic initiation factor 4E family O60573
Phakinin (BFSP2) Intermediate filament family Q13515
Prelamin-A/C (LMNA) Intermediate filament family P02545
Mediator of RNA polymerase II transcription subunit 25 (MED25) Mediator complex subunit 25 family Q71SY5
Protein Mis18-beta (OIP5) Mis18 family O43482
RNA guanine-N7 methyltransferase activating subunit (RAMAC) RAM family Q9BTL3
tRNA-splicing endonuclease subunit Sen15 (TSEN15) SEN15 family Q8WW01
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) SMARCD family Q96GM5
Tektin-5 (TEKT5) Tektin family Q96M29
Transcription elongation factor A protein 2 (TCEA2) TFS-II family Q15560
Toll-interacting protein (TOLLIP) Tollip family Q9H0E2
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) TTC19 family Q6DKK2
Armadillo repeat-containing protein 7 (ARMC7) . Q9H6L4
BTB/POZ domain-containing protein KCTD9 (KCTD9) . Q7L273
Calcium homeostasis endoplasmic reticulum protein (CHERP) . Q8IWX8
Caspase recruitment domain-containing protein 10 (CARD10) . Q9BWT7
Cleavage stimulation factor subunit 2 (CSTF2) . P33240
Coiled-coil domain-containing protein 13 (CCDC13) . Q8IYE1
Coiled-coil domain-containing protein 24 (CCDC24) . Q8N4L8
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) . Q9Y6H1
EPM2A-interacting protein 1 (EPM2AIP1) . Q7L775
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) . P52597
NTF2-related export protein 2 (NXT2) . Q9NPJ8
Proline-rich protein 35 (PRR35) . P0CG20
Protein inscuteable homolog (INSC) . Q1MX18
RNA-binding protein with multiple splicing 2 (RBPMS2) . Q6ZRY4
SHC-transforming protein 3 (SHC3) . Q92529
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699
Zinc finger CCHC domain-containing protein 14 (ZCCHC14) . Q8WYQ9

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
9 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402