Details of the Target
General Information of Target
Target ID | LDTP06349 | |||||
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Target Name | Ras-related protein Rab-35 (RAB35) | |||||
Gene Name | RAB35 | |||||
Gene ID | 11021 | |||||
Synonyms |
RAB1C; RAY; Ras-related protein Rab-35; GTP-binding protein RAY; Ras-related protein Rab-1C |
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3D Structure | ||||||
Sequence |
MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ
IWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGN KNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQ QQQQNDVVKLTKNSKRKKRCC |
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Target Bioclass |
Enzyme
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Family |
Small GTPase superfamily, Rab family
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Subcellular location |
Cell membrane
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Function |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Target Site Mutations in Different Cell Lines
Cell line | Mutation details | Probe for labeling this protein in this cell | |||
---|---|---|---|---|---|
HCT116 | SNV: p.R27C; p.G80E | DBIA Probe Info | |||
MOLT4 | SNV: p.A151T | . | |||
OVK18 | SNV: p.E105K | DBIA Probe Info | |||
PF382 | SNV: p.V157A | DBIA Probe Info |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
m-APA Probe Info |
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9.86 | LDD0402 | [1] | |
AZ-9 Probe Info |
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D112(10.00) | LDD2209 | [2] | |
IPM Probe Info |
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C110(0.00); C114(0.00) | LDD0241 | [3] | |
OPA-S-S-alkyne Probe Info |
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K121(0.72) | LDD3494 | [4] | |
Probe 1 Probe Info |
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Y136(113.63) | LDD3495 | [5] | |
DBIA Probe Info |
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C110(1.22); C114(1.23) | LDD0531 | [6] | |
ATP probe Probe Info |
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N.A. | LDD0199 | [7] | |
4-Iodoacetamidophenylacetylene Probe Info |
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N.A. | LDD0038 | [8] | |
IA-alkyne Probe Info |
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C163(0.00); C114(0.00); C110(0.00) | LDD0036 | [8] | |
Lodoacetamide azide Probe Info |
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N.A. | LDD0037 | [8] | |
NAIA_4 Probe Info |
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N.A. | LDD2226 | [9] | |
SF Probe Info |
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Y136(0.00); K121(0.00); Y5(0.00) | LDD0028 | [10] | |
STPyne Probe Info |
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N.A. | LDD0009 | [11] | |
Acrolein Probe Info |
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C110(0.00); C114(0.00) | LDD0217 | [12] | |
Methacrolein Probe Info |
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C110(0.00); C114(0.00) | LDD0218 | [12] | |
W1 Probe Info |
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C110(0.00); C114(0.00) | LDD0236 | [3] | |
AOyne Probe Info |
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9.70 | LDD0443 | [13] | |
NAIA_5 Probe Info |
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N.A. | LDD2223 | [9] |
PAL-AfBPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
STS-1 Probe Info |
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N.A. | LDD0137 | [14] | |
STS-2 Probe Info |
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N.A. | LDD0138 | [14] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0214 | AC1 | HCT 116 | C110(1.22); C114(1.23) | LDD0531 | [6] |
LDCM0215 | AC10 | HCT 116 | C110(1.19); C114(1.16) | LDD0532 | [6] |
LDCM0216 | AC100 | HCT 116 | C110(1.01); C114(1.04) | LDD0533 | [6] |
LDCM0217 | AC101 | HCT 116 | C110(0.99); C114(0.97) | LDD0534 | [6] |
LDCM0218 | AC102 | HCT 116 | C110(0.80); C114(0.81) | LDD0535 | [6] |
LDCM0219 | AC103 | HCT 116 | C110(0.71); C114(0.72) | LDD0536 | [6] |
LDCM0220 | AC104 | HCT 116 | C110(0.78); C114(0.79) | LDD0537 | [6] |
LDCM0221 | AC105 | HCT 116 | C110(0.75); C114(0.76) | LDD0538 | [6] |
LDCM0222 | AC106 | HCT 116 | C110(0.87); C114(0.87) | LDD0539 | [6] |
LDCM0223 | AC107 | HCT 116 | C110(0.96); C114(0.96) | LDD0540 | [6] |
LDCM0224 | AC108 | HCT 116 | C110(0.88); C114(0.90) | LDD0541 | [6] |
LDCM0225 | AC109 | HCT 116 | C110(1.00); C114(1.01) | LDD0542 | [6] |
LDCM0226 | AC11 | HCT 116 | C110(1.16); C114(1.05) | LDD0543 | [6] |
LDCM0227 | AC110 | HCT 116 | C110(0.79); C114(0.80) | LDD0544 | [6] |
LDCM0228 | AC111 | HCT 116 | C110(0.86); C114(0.86) | LDD0545 | [6] |
LDCM0229 | AC112 | HCT 116 | C110(0.89); C114(0.83) | LDD0546 | [6] |
LDCM0230 | AC113 | HCT 116 | C110(1.04); C114(1.07) | LDD0547 | [6] |
LDCM0231 | AC114 | HCT 116 | C110(1.10); C114(1.21) | LDD0548 | [6] |
LDCM0232 | AC115 | HCT 116 | C110(0.92); C114(1.02) | LDD0549 | [6] |
LDCM0233 | AC116 | HCT 116 | C110(1.10); C114(1.27) | LDD0550 | [6] |
LDCM0234 | AC117 | HCT 116 | C110(0.97); C114(0.99) | LDD0551 | [6] |
LDCM0235 | AC118 | HCT 116 | C110(1.00); C114(1.06) | LDD0552 | [6] |
LDCM0236 | AC119 | HCT 116 | C110(1.00); C114(0.96) | LDD0553 | [6] |
LDCM0237 | AC12 | HCT 116 | C110(1.19); C114(1.10) | LDD0554 | [6] |
LDCM0238 | AC120 | HCT 116 | C110(1.09); C114(1.19) | LDD0555 | [6] |
LDCM0239 | AC121 | HCT 116 | C110(1.31); C114(1.47) | LDD0556 | [6] |
LDCM0240 | AC122 | HCT 116 | C110(1.30); C114(1.67) | LDD0557 | [6] |
LDCM0241 | AC123 | HCT 116 | C110(1.41); C114(1.39) | LDD0558 | [6] |
LDCM0242 | AC124 | HCT 116 | C110(1.23); C114(1.48) | LDD0559 | [6] |
LDCM0243 | AC125 | HCT 116 | C110(1.36); C114(1.74) | LDD0560 | [6] |
LDCM0244 | AC126 | HCT 116 | C110(1.42); C114(1.88) | LDD0561 | [6] |
LDCM0245 | AC127 | HCT 116 | C110(1.36); C114(1.79) | LDD0562 | [6] |
LDCM0246 | AC128 | HCT 116 | C114(0.77) | LDD0563 | [6] |
LDCM0247 | AC129 | HCT 116 | C114(1.48) | LDD0564 | [6] |
LDCM0249 | AC130 | HCT 116 | C114(0.99) | LDD0566 | [6] |
LDCM0250 | AC131 | HCT 116 | C114(1.37) | LDD0567 | [6] |
LDCM0251 | AC132 | HCT 116 | C114(1.50) | LDD0568 | [6] |
LDCM0252 | AC133 | HCT 116 | C114(1.12) | LDD0569 | [6] |
LDCM0253 | AC134 | HCT 116 | C114(1.01) | LDD0570 | [6] |
LDCM0254 | AC135 | HCT 116 | C114(1.01) | LDD0571 | [6] |
LDCM0255 | AC136 | HCT 116 | C114(1.08) | LDD0572 | [6] |
LDCM0256 | AC137 | HCT 116 | C114(1.33) | LDD0573 | [6] |
LDCM0257 | AC138 | HCT 116 | C114(1.07) | LDD0574 | [6] |
LDCM0258 | AC139 | HCT 116 | C114(1.23) | LDD0575 | [6] |
LDCM0259 | AC14 | HCT 116 | C110(1.26); C114(1.03) | LDD0576 | [6] |
LDCM0260 | AC140 | HCT 116 | C114(1.09) | LDD0577 | [6] |
LDCM0261 | AC141 | HCT 116 | C114(1.04) | LDD0578 | [6] |
LDCM0262 | AC142 | HCT 116 | C114(1.85) | LDD0579 | [6] |
LDCM0263 | AC143 | HCT 116 | C114(0.89); C110(1.03) | LDD0580 | [6] |
LDCM0264 | AC144 | HCT 116 | C114(0.76); C110(0.96) | LDD0581 | [6] |
LDCM0265 | AC145 | HCT 116 | C114(0.81); C110(0.88) | LDD0582 | [6] |
LDCM0266 | AC146 | HCT 116 | C114(0.91); C110(1.09) | LDD0583 | [6] |
LDCM0267 | AC147 | HCT 116 | C114(0.76); C110(0.91) | LDD0584 | [6] |
LDCM0268 | AC148 | HCT 116 | C114(0.73); C110(0.76) | LDD0585 | [6] |
LDCM0269 | AC149 | HCT 116 | C114(0.78); C110(0.83) | LDD0586 | [6] |
LDCM0270 | AC15 | HCT 116 | C114(1.11); C110(1.17) | LDD0587 | [6] |
LDCM0271 | AC150 | HCT 116 | C114(0.89); C110(1.21) | LDD0588 | [6] |
LDCM0272 | AC151 | HCT 116 | C114(0.93); C110(1.14) | LDD0589 | [6] |
LDCM0273 | AC152 | HCT 116 | C114(0.67); C110(0.76) | LDD0590 | [6] |
LDCM0274 | AC153 | HCT 116 | C114(0.71); C110(0.80) | LDD0591 | [6] |
LDCM0621 | AC154 | HCT 116 | C110(0.95); C114(0.73) | LDD2158 | [6] |
LDCM0622 | AC155 | HCT 116 | C110(1.03); C114(0.76) | LDD2159 | [6] |
LDCM0623 | AC156 | HCT 116 | C110(1.05); C114(0.99) | LDD2160 | [6] |
LDCM0624 | AC157 | HCT 116 | C110(0.92); C114(0.82) | LDD2161 | [6] |
LDCM0276 | AC17 | HCT 116 | C110(0.96); C114(1.04) | LDD0593 | [6] |
LDCM0277 | AC18 | HCT 116 | C110(0.82); C114(0.92) | LDD0594 | [6] |
LDCM0278 | AC19 | HCT 116 | C110(0.90); C114(1.02) | LDD0595 | [6] |
LDCM0279 | AC2 | HCT 116 | C114(1.21); C110(1.30) | LDD0596 | [6] |
LDCM0280 | AC20 | HCT 116 | C110(0.88); C114(0.95) | LDD0597 | [6] |
LDCM0281 | AC21 | HCT 116 | C110(0.80); C114(0.98) | LDD0598 | [6] |
LDCM0282 | AC22 | HCT 116 | C110(0.92); C114(1.09) | LDD0599 | [6] |
LDCM0283 | AC23 | HCT 116 | C110(0.91); C114(0.98) | LDD0600 | [6] |
LDCM0284 | AC24 | HCT 116 | C110(0.94); C114(0.96) | LDD0601 | [6] |
LDCM0285 | AC25 | HCT 116 | C110(0.92); C114(0.96) | LDD0602 | [6] |
LDCM0286 | AC26 | HCT 116 | C114(0.79); C110(0.88) | LDD0603 | [6] |
LDCM0287 | AC27 | HCT 116 | C110(0.80); C114(0.82) | LDD0604 | [6] |
LDCM0288 | AC28 | HCT 116 | C114(0.68); C110(0.80) | LDD0605 | [6] |
LDCM0289 | AC29 | HCT 116 | C114(0.89); C110(0.97) | LDD0606 | [6] |
LDCM0290 | AC3 | HCT 116 | C114(1.14); C110(1.18) | LDD0607 | [6] |
LDCM0291 | AC30 | HCT 116 | C114(0.75); C110(0.89) | LDD0608 | [6] |
LDCM0292 | AC31 | HCT 116 | C114(0.87); C110(0.91) | LDD0609 | [6] |
LDCM0293 | AC32 | HCT 116 | C114(0.72); C110(0.76) | LDD0610 | [6] |
LDCM0294 | AC33 | HCT 116 | C110(0.68); C114(0.69) | LDD0611 | [6] |
LDCM0295 | AC34 | HCT 116 | C114(0.55); C110(0.57) | LDD0612 | [6] |
LDCM0296 | AC35 | HCT 116 | C114(0.92); C110(1.05) | LDD0613 | [6] |
LDCM0297 | AC36 | HCT 116 | C114(0.84); C110(1.15) | LDD0614 | [6] |
LDCM0298 | AC37 | HCT 116 | C114(0.83); C110(0.95) | LDD0615 | [6] |
LDCM0299 | AC38 | HCT 116 | C114(0.91); C110(0.94) | LDD0616 | [6] |
LDCM0300 | AC39 | HCT 116 | C114(0.99); C110(1.15) | LDD0617 | [6] |
LDCM0301 | AC4 | HCT 116 | C114(1.01); C110(1.08) | LDD0618 | [6] |
LDCM0302 | AC40 | HCT 116 | C114(0.89); C110(0.90) | LDD0619 | [6] |
LDCM0303 | AC41 | HCT 116 | C110(0.94); C114(0.98) | LDD0620 | [6] |
LDCM0304 | AC42 | HCT 116 | C114(0.83); C110(0.97) | LDD0621 | [6] |
LDCM0305 | AC43 | HCT 116 | C114(0.82); C110(1.03) | LDD0622 | [6] |
LDCM0306 | AC44 | HCT 116 | C114(0.90); C110(0.97) | LDD0623 | [6] |
LDCM0307 | AC45 | HCT 116 | C114(0.75); C110(0.81) | LDD0624 | [6] |
LDCM0308 | AC46 | HCT 116 | C114(0.84); C110(1.05) | LDD0625 | [6] |
LDCM0309 | AC47 | HCT 116 | C114(0.88); C110(0.98) | LDD0626 | [6] |
LDCM0310 | AC48 | HCT 116 | C114(0.77); C110(1.35) | LDD0627 | [6] |
LDCM0311 | AC49 | HCT 116 | C110(0.73); C114(0.84) | LDD0628 | [6] |
LDCM0312 | AC5 | HCT 116 | C114(1.16); C110(1.24) | LDD0629 | [6] |
LDCM0313 | AC50 | HCT 116 | C110(0.72); C114(0.77) | LDD0630 | [6] |
LDCM0314 | AC51 | HCT 116 | C114(0.82); C110(0.94) | LDD0631 | [6] |
LDCM0315 | AC52 | HCT 116 | C114(0.79); C110(0.93) | LDD0632 | [6] |
LDCM0316 | AC53 | HCT 116 | C110(0.85); C114(0.93) | LDD0633 | [6] |
LDCM0317 | AC54 | HCT 116 | C110(0.78); C114(0.82) | LDD0634 | [6] |
LDCM0318 | AC55 | HCT 116 | C110(0.71); C114(0.89) | LDD0635 | [6] |
LDCM0319 | AC56 | HCT 116 | C110(0.73); C114(0.80) | LDD0636 | [6] |
LDCM0320 | AC57 | HCT 116 | C110(0.72); C114(0.75) | LDD0637 | [6] |
LDCM0321 | AC58 | HCT 116 | C114(0.61); C110(0.63) | LDD0638 | [6] |
LDCM0322 | AC59 | HCT 116 | C110(0.62); C114(0.66) | LDD0639 | [6] |
LDCM0323 | AC6 | HCT 116 | C114(0.93); C110(0.99) | LDD0640 | [6] |
LDCM0324 | AC60 | HCT 116 | C110(0.97); C114(1.02) | LDD0641 | [6] |
LDCM0325 | AC61 | HCT 116 | C110(1.42); C114(1.43) | LDD0642 | [6] |
LDCM0326 | AC62 | HCT 116 | C110(0.79); C114(0.80) | LDD0643 | [6] |
LDCM0327 | AC63 | HCT 116 | C110(0.78); C114(0.80) | LDD0644 | [6] |
LDCM0328 | AC64 | HCT 116 | C110(0.79); C114(0.82) | LDD0645 | [6] |
LDCM0329 | AC65 | HCT 116 | C110(0.82); C114(0.86) | LDD0646 | [6] |
LDCM0330 | AC66 | HCT 116 | C110(0.92); C114(0.95) | LDD0647 | [6] |
LDCM0331 | AC67 | HCT 116 | C110(0.67); C114(0.70) | LDD0648 | [6] |
LDCM0332 | AC68 | HCT 116 | C110(0.86); C114(0.91) | LDD0649 | [6] |
LDCM0333 | AC69 | HCT 116 | C110(0.84); C114(0.95) | LDD0650 | [6] |
LDCM0334 | AC7 | HCT 116 | C114(1.04); C110(1.22) | LDD0651 | [6] |
LDCM0335 | AC70 | HCT 116 | C110(0.70); C114(0.75) | LDD0652 | [6] |
LDCM0336 | AC71 | HCT 116 | C114(1.00); C110(1.11) | LDD0653 | [6] |
LDCM0337 | AC72 | HCT 116 | C114(0.91); C110(0.94) | LDD0654 | [6] |
LDCM0338 | AC73 | HCT 116 | C110(0.78); C114(0.83) | LDD0655 | [6] |
LDCM0339 | AC74 | HCT 116 | C110(0.80); C114(0.91) | LDD0656 | [6] |
LDCM0340 | AC75 | HCT 116 | C110(0.70); C114(0.93) | LDD0657 | [6] |
LDCM0341 | AC76 | HCT 116 | C110(0.82); C114(0.98) | LDD0658 | [6] |
LDCM0342 | AC77 | HCT 116 | C110(0.71); C114(0.90) | LDD0659 | [6] |
LDCM0343 | AC78 | HCT 116 | C114(0.98); C110(1.15) | LDD0660 | [6] |
LDCM0344 | AC79 | HCT 116 | C114(0.95); C110(1.01) | LDD0661 | [6] |
LDCM0345 | AC8 | HCT 116 | C114(1.02); C110(1.02) | LDD0662 | [6] |
LDCM0346 | AC80 | HCT 116 | C110(0.93); C114(1.15) | LDD0663 | [6] |
LDCM0347 | AC81 | HCT 116 | C114(0.95); C110(1.03) | LDD0664 | [6] |
LDCM0348 | AC82 | HCT 116 | C110(0.81); C114(1.02) | LDD0665 | [6] |
LDCM0349 | AC83 | HCT 116 | C114(0.75); C110(1.00) | LDD0666 | [6] |
LDCM0350 | AC84 | HCT 116 | C114(0.73); C110(1.01) | LDD0667 | [6] |
LDCM0351 | AC85 | HCT 116 | C110(0.92); C114(0.94) | LDD0668 | [6] |
LDCM0352 | AC86 | HCT 116 | C114(0.88); C110(0.94) | LDD0669 | [6] |
LDCM0353 | AC87 | HCT 116 | C114(1.04); C110(1.10) | LDD0670 | [6] |
LDCM0354 | AC88 | HCT 116 | C114(0.84); C110(1.16) | LDD0671 | [6] |
LDCM0355 | AC89 | HCT 116 | C114(0.85); C110(1.26) | LDD0672 | [6] |
LDCM0357 | AC90 | HCT 116 | C114(0.95); C110(1.28) | LDD0674 | [6] |
LDCM0358 | AC91 | HCT 116 | C114(0.67); C110(0.86) | LDD0675 | [6] |
LDCM0359 | AC92 | HCT 116 | C114(0.74); C110(1.05) | LDD0676 | [6] |
LDCM0360 | AC93 | HCT 116 | C114(0.83); C110(1.24) | LDD0677 | [6] |
LDCM0361 | AC94 | HCT 116 | C114(1.11); C110(1.36) | LDD0678 | [6] |
LDCM0362 | AC95 | HCT 116 | C114(0.91); C110(1.01) | LDD0679 | [6] |
LDCM0363 | AC96 | HCT 116 | C114(0.82); C110(0.98) | LDD0680 | [6] |
LDCM0364 | AC97 | HCT 116 | C114(0.74); C110(1.00) | LDD0681 | [6] |
LDCM0365 | AC98 | HCT 116 | C114(0.61); C110(0.62) | LDD0682 | [6] |
LDCM0366 | AC99 | HCT 116 | C110(1.08); C114(1.08) | LDD0683 | [6] |
LDCM0248 | AKOS034007472 | HCT 116 | C110(1.39); C114(1.03) | LDD0565 | [6] |
LDCM0356 | AKOS034007680 | HCT 116 | C114(1.10); C110(1.34) | LDD0673 | [6] |
LDCM0275 | AKOS034007705 | HCT 116 | C110(0.98); C114(1.07) | LDD0592 | [6] |
LDCM0156 | Aniline | NCI-H1299 | 11.43 | LDD0403 | [1] |
LDCM0020 | ARS-1620 | HCC44 | C110(1.09); C114(1.09) | LDD2171 | [6] |
LDCM0108 | Chloroacetamide | HeLa | C110(0.00); C114(0.00) | LDD0222 | [12] |
LDCM0367 | CL1 | HCT 116 | C114(0.85); C110(0.88) | LDD0684 | [6] |
LDCM0368 | CL10 | HCT 116 | C114(1.09); C110(1.15) | LDD0685 | [6] |
LDCM0369 | CL100 | HCT 116 | C110(1.03); C114(1.04) | LDD0686 | [6] |
LDCM0370 | CL101 | HCT 116 | C114(1.08); C110(1.08) | LDD0687 | [6] |
LDCM0371 | CL102 | HCT 116 | C114(1.18); C110(1.23) | LDD0688 | [6] |
LDCM0372 | CL103 | HCT 116 | C110(1.37); C114(1.43) | LDD0689 | [6] |
LDCM0373 | CL104 | HCT 116 | C114(1.26); C110(1.26) | LDD0690 | [6] |
LDCM0374 | CL105 | HCT 116 | C110(0.86); C114(0.90) | LDD0691 | [6] |
LDCM0375 | CL106 | HCT 116 | C110(0.79); C114(0.94) | LDD0692 | [6] |
LDCM0376 | CL107 | HCT 116 | C110(0.73); C114(0.92) | LDD0693 | [6] |
LDCM0377 | CL108 | HCT 116 | C110(0.86); C114(0.88) | LDD0694 | [6] |
LDCM0378 | CL109 | HCT 116 | C110(0.93); C114(1.04) | LDD0695 | [6] |
LDCM0379 | CL11 | HCT 116 | C110(0.95); C114(1.04) | LDD0696 | [6] |
LDCM0380 | CL110 | HCT 116 | C110(0.87); C114(1.14) | LDD0697 | [6] |
LDCM0381 | CL111 | HCT 116 | C110(0.82); C114(0.93) | LDD0698 | [6] |
LDCM0382 | CL112 | HCT 116 | C110(0.91); C114(0.95) | LDD0699 | [6] |
LDCM0383 | CL113 | HCT 116 | C114(0.78); C110(0.80) | LDD0700 | [6] |
LDCM0384 | CL114 | HCT 116 | C114(1.01); C110(1.01) | LDD0701 | [6] |
LDCM0385 | CL115 | HCT 116 | C110(0.79); C114(0.80) | LDD0702 | [6] |
LDCM0386 | CL116 | HCT 116 | C114(0.77); C110(0.78) | LDD0703 | [6] |
LDCM0387 | CL117 | HCT 116 | C110(0.78); C114(0.81) | LDD0704 | [6] |
LDCM0388 | CL118 | HCT 116 | C114(0.88); C110(0.97) | LDD0705 | [6] |
LDCM0389 | CL119 | HCT 116 | C110(0.91); C114(0.97) | LDD0706 | [6] |
LDCM0390 | CL12 | HCT 116 | C110(1.05); C114(1.19) | LDD0707 | [6] |
LDCM0391 | CL120 | HCT 116 | C114(0.84); C110(1.18) | LDD0708 | [6] |
LDCM0392 | CL121 | HCT 116 | C110(0.63); C114(0.92) | LDD0709 | [6] |
LDCM0393 | CL122 | HCT 116 | C114(0.90); C110(1.08) | LDD0710 | [6] |
LDCM0394 | CL123 | HCT 116 | C110(0.83); C114(0.93) | LDD0711 | [6] |
LDCM0395 | CL124 | HCT 116 | C114(0.81); C110(0.82) | LDD0712 | [6] |
LDCM0396 | CL125 | HCT 116 | C110(0.94); C114(0.97) | LDD0713 | [6] |
LDCM0397 | CL126 | HCT 116 | C110(0.74); C114(0.78) | LDD0714 | [6] |
LDCM0398 | CL127 | HCT 116 | C110(1.03); C114(1.16) | LDD0715 | [6] |
LDCM0399 | CL128 | HCT 116 | C110(0.65); C114(0.66) | LDD0716 | [6] |
LDCM0400 | CL13 | HCT 116 | C114(1.11); C110(1.16) | LDD0717 | [6] |
LDCM0401 | CL14 | HCT 116 | C114(1.01); C110(1.01) | LDD0718 | [6] |
LDCM0402 | CL15 | HCT 116 | C114(1.25); C110(1.35) | LDD0719 | [6] |
LDCM0403 | CL16 | HCT 116 | C114(0.92); C110(0.96) | LDD0720 | [6] |
LDCM0404 | CL17 | HCT 116 | C114(0.98); C110(1.08) | LDD0721 | [6] |
LDCM0405 | CL18 | HCT 116 | C110(1.03); C114(1.04) | LDD0722 | [6] |
LDCM0406 | CL19 | HCT 116 | C114(1.05); C110(1.21) | LDD0723 | [6] |
LDCM0407 | CL2 | HCT 116 | C110(1.02); C114(1.05) | LDD0724 | [6] |
LDCM0408 | CL20 | HCT 116 | C114(0.88); C110(1.17) | LDD0725 | [6] |
LDCM0409 | CL21 | HCT 116 | C114(0.80); C110(1.11) | LDD0726 | [6] |
LDCM0410 | CL22 | HCT 116 | C114(0.78); C110(1.10) | LDD0727 | [6] |
LDCM0411 | CL23 | HCT 116 | C114(0.90); C110(1.14) | LDD0728 | [6] |
LDCM0412 | CL24 | HCT 116 | C110(1.17); C114(0.81) | LDD0729 | [6] |
LDCM0413 | CL25 | HCT 116 | C110(0.99); C114(0.76) | LDD0730 | [6] |
LDCM0414 | CL26 | HCT 116 | C110(0.91); C114(0.96) | LDD0731 | [6] |
LDCM0415 | CL27 | HCT 116 | C110(1.18); C114(1.00) | LDD0732 | [6] |
LDCM0416 | CL28 | HCT 116 | C110(1.12); C114(0.85) | LDD0733 | [6] |
LDCM0417 | CL29 | HCT 116 | C110(1.33); C114(0.99) | LDD0734 | [6] |
LDCM0418 | CL3 | HCT 116 | C110(0.99); C114(1.07) | LDD0735 | [6] |
LDCM0419 | CL30 | HCT 116 | C110(1.26); C114(1.08) | LDD0736 | [6] |
LDCM0420 | CL31 | HCT 116 | C110(0.79); C114(0.84) | LDD0737 | [6] |
LDCM0421 | CL32 | HCT 116 | C110(0.80); C114(0.95) | LDD0738 | [6] |
LDCM0422 | CL33 | HCT 116 | C110(0.73); C114(0.88) | LDD0739 | [6] |
LDCM0423 | CL34 | HCT 116 | C110(0.93); C114(1.10) | LDD0740 | [6] |
LDCM0424 | CL35 | HCT 116 | C110(0.90); C114(1.00) | LDD0741 | [6] |
LDCM0425 | CL36 | HCT 116 | C110(0.74); C114(0.83) | LDD0742 | [6] |
LDCM0426 | CL37 | HCT 116 | C110(0.72); C114(0.81) | LDD0743 | [6] |
LDCM0428 | CL39 | HCT 116 | C110(0.73); C114(0.89) | LDD0745 | [6] |
LDCM0429 | CL4 | HCT 116 | C110(0.93); C114(1.12) | LDD0746 | [6] |
LDCM0430 | CL40 | HCT 116 | C110(0.71); C114(0.77) | LDD0747 | [6] |
LDCM0431 | CL41 | HCT 116 | C110(0.78); C114(0.85) | LDD0748 | [6] |
LDCM0432 | CL42 | HCT 116 | C110(0.79); C114(0.88) | LDD0749 | [6] |
LDCM0433 | CL43 | HCT 116 | C110(0.91); C114(0.95) | LDD0750 | [6] |
LDCM0434 | CL44 | HCT 116 | C110(0.87); C114(0.90) | LDD0751 | [6] |
LDCM0435 | CL45 | HCT 116 | C110(1.07); C114(1.03) | LDD0752 | [6] |
LDCM0436 | CL46 | HCT 116 | C110(1.44); C114(1.28) | LDD0753 | [6] |
LDCM0437 | CL47 | HCT 116 | C110(1.46); C114(1.28) | LDD0754 | [6] |
LDCM0438 | CL48 | HCT 116 | C110(1.20); C114(1.19) | LDD0755 | [6] |
LDCM0439 | CL49 | HCT 116 | C110(1.25); C114(1.07) | LDD0756 | [6] |
LDCM0440 | CL5 | HCT 116 | C110(1.02); C114(1.16) | LDD0757 | [6] |
LDCM0441 | CL50 | HCT 116 | C110(1.26); C114(1.01) | LDD0758 | [6] |
LDCM0442 | CL51 | HCT 116 | C110(1.20); C114(1.12) | LDD0759 | [6] |
LDCM0443 | CL52 | HCT 116 | C110(1.28); C114(1.13) | LDD0760 | [6] |
LDCM0444 | CL53 | HCT 116 | C110(1.08); C114(0.98) | LDD0761 | [6] |
LDCM0445 | CL54 | HCT 116 | C110(1.39); C114(1.13) | LDD0762 | [6] |
LDCM0446 | CL55 | HCT 116 | C110(1.24); C114(1.06) | LDD0763 | [6] |
LDCM0447 | CL56 | HCT 116 | C110(1.21); C114(1.10) | LDD0764 | [6] |
LDCM0448 | CL57 | HCT 116 | C110(1.26); C114(1.17) | LDD0765 | [6] |
LDCM0449 | CL58 | HCT 116 | C110(1.52); C114(1.29) | LDD0766 | [6] |
LDCM0450 | CL59 | HCT 116 | C110(1.21); C114(1.05) | LDD0767 | [6] |
LDCM0451 | CL6 | HCT 116 | C110(1.02); C114(1.18) | LDD0768 | [6] |
LDCM0452 | CL60 | HCT 116 | C110(1.11); C114(0.98) | LDD0769 | [6] |
LDCM0453 | CL61 | HCT 116 | C110(0.98); C114(1.09) | LDD0770 | [6] |
LDCM0454 | CL62 | HCT 116 | C110(0.99); C114(1.08) | LDD0771 | [6] |
LDCM0455 | CL63 | HCT 116 | C110(0.63); C114(0.85) | LDD0772 | [6] |
LDCM0456 | CL64 | HCT 116 | C110(0.52); C114(0.84) | LDD0773 | [6] |
LDCM0457 | CL65 | HCT 116 | C110(1.18); C114(1.33) | LDD0774 | [6] |
LDCM0458 | CL66 | HCT 116 | C110(0.39); C114(0.66) | LDD0775 | [6] |
LDCM0459 | CL67 | HCT 116 | C110(0.47); C114(0.67) | LDD0776 | [6] |
LDCM0460 | CL68 | HCT 116 | C110(0.78); C114(0.99) | LDD0777 | [6] |
LDCM0461 | CL69 | HCT 116 | C110(1.06); C114(1.19) | LDD0778 | [6] |
LDCM0462 | CL7 | HCT 116 | C110(1.05); C114(1.22) | LDD0779 | [6] |
LDCM0463 | CL70 | HCT 116 | C110(0.82); C114(0.93) | LDD0780 | [6] |
LDCM0464 | CL71 | HCT 116 | C110(0.56); C114(0.76) | LDD0781 | [6] |
LDCM0465 | CL72 | HCT 116 | C110(0.95); C114(1.11) | LDD0782 | [6] |
LDCM0466 | CL73 | HCT 116 | C110(0.66); C114(0.87) | LDD0783 | [6] |
LDCM0467 | CL74 | HCT 116 | C110(0.60); C114(0.83) | LDD0784 | [6] |
LDCM0469 | CL76 | HCT 116 | C110(0.79); C114(0.92) | LDD0786 | [6] |
LDCM0470 | CL77 | HCT 116 | C110(0.88); C114(0.87) | LDD0787 | [6] |
LDCM0471 | CL78 | HCT 116 | C110(0.70); C114(0.78) | LDD0788 | [6] |
LDCM0472 | CL79 | HCT 116 | C110(0.62); C114(0.76) | LDD0789 | [6] |
LDCM0473 | CL8 | HCT 116 | C110(0.96); C114(0.80) | LDD0790 | [6] |
LDCM0474 | CL80 | HCT 116 | C110(1.00); C114(1.10) | LDD0791 | [6] |
LDCM0475 | CL81 | HCT 116 | C110(0.67); C114(0.79) | LDD0792 | [6] |
LDCM0476 | CL82 | HCT 116 | C110(0.59); C114(0.71) | LDD0793 | [6] |
LDCM0477 | CL83 | HCT 116 | C110(0.53); C114(0.68) | LDD0794 | [6] |
LDCM0478 | CL84 | HCT 116 | C110(0.57); C114(0.65) | LDD0795 | [6] |
LDCM0479 | CL85 | HCT 116 | C110(0.69); C114(0.76) | LDD0796 | [6] |
LDCM0480 | CL86 | HCT 116 | C110(0.80); C114(0.91) | LDD0797 | [6] |
LDCM0481 | CL87 | HCT 116 | C110(0.73); C114(0.81) | LDD0798 | [6] |
LDCM0482 | CL88 | HCT 116 | C110(0.64); C114(0.67) | LDD0799 | [6] |
LDCM0483 | CL89 | HCT 116 | C110(0.58); C114(0.66) | LDD0800 | [6] |
LDCM0484 | CL9 | HCT 116 | C110(1.03); C114(1.06) | LDD0801 | [6] |
LDCM0485 | CL90 | HCT 116 | C110(0.91); C114(0.89) | LDD0802 | [6] |
LDCM0486 | CL91 | HCT 116 | C110(1.06); C114(0.96) | LDD0803 | [6] |
LDCM0487 | CL92 | HCT 116 | C110(0.95); C114(0.96) | LDD0804 | [6] |
LDCM0488 | CL93 | HCT 116 | C110(1.03); C114(0.97) | LDD0805 | [6] |
LDCM0489 | CL94 | HCT 116 | C110(1.13); C114(1.03) | LDD0806 | [6] |
LDCM0490 | CL95 | HCT 116 | C110(1.13); C114(0.98) | LDD0807 | [6] |
LDCM0491 | CL96 | HCT 116 | C110(1.14); C114(0.91) | LDD0808 | [6] |
LDCM0492 | CL97 | HCT 116 | C110(1.07); C114(0.92) | LDD0809 | [6] |
LDCM0493 | CL98 | HCT 116 | C110(1.02); C114(0.92) | LDD0810 | [6] |
LDCM0494 | CL99 | HCT 116 | C110(1.12); C114(0.98) | LDD0811 | [6] |
LDCM0495 | E2913 | HEK-293T | C163(0.85); C114(0.93); C110(0.94) | LDD1698 | [15] |
LDCM0625 | F8 | Ramos | 0.74 | LDD2187 | [16] |
LDCM0572 | Fragment10 | Ramos | 0.93 | LDD2189 | [16] |
LDCM0573 | Fragment11 | Ramos | 3.53 | LDD2190 | [16] |
LDCM0574 | Fragment12 | Ramos | 0.94 | LDD2191 | [16] |
LDCM0576 | Fragment14 | Ramos | 0.58 | LDD2193 | [16] |
LDCM0579 | Fragment20 | Ramos | 1.01 | LDD2194 | [16] |
LDCM0580 | Fragment21 | Ramos | 1.31 | LDD2195 | [16] |
LDCM0586 | Fragment28 | Ramos | 0.82 | LDD2198 | [16] |
LDCM0588 | Fragment30 | Ramos | 0.87 | LDD2199 | [16] |
LDCM0590 | Fragment32 | Ramos | 0.95 | LDD2201 | [16] |
LDCM0468 | Fragment33 | HCT 116 | C110(0.63); C114(0.94) | LDD0785 | [6] |
LDCM0596 | Fragment38 | Ramos | 0.76 | LDD2203 | [16] |
LDCM0566 | Fragment4 | Ramos | 1.00 | LDD2184 | [16] |
LDCM0427 | Fragment51 | HCT 116 | C110(0.54); C114(0.65) | LDD0744 | [6] |
LDCM0610 | Fragment52 | Ramos | 1.11 | LDD2204 | [16] |
LDCM0614 | Fragment56 | Ramos | 1.44 | LDD2205 | [16] |
LDCM0569 | Fragment7 | Ramos | 0.80 | LDD2186 | [16] |
LDCM0571 | Fragment9 | Ramos | 0.60 | LDD2188 | [16] |
LDCM0107 | IAA | HeLa | C110(0.00); C114(0.00) | LDD0221 | [12] |
LDCM0022 | KB02 | HEK-293T | C163(0.94); C114(1.01) | LDD1492 | [15] |
LDCM0023 | KB03 | HEK-293T | C163(0.97); C114(1.04) | LDD1497 | [15] |
LDCM0024 | KB05 | COLO792 | C163(0.85) | LDD3310 | [17] |
LDCM0021 | THZ1 | HCT 116 | C110(1.09); C114(1.09) | LDD2173 | [6] |
The Interaction Atlas With This Target
References