Details of the Target

General Information of Target

Target ID LDTP02605
Target Name Collagen alpha-1(VI) chain (COL6A1)
Gene Name COL6A1
Gene ID 1291
Synonyms
Collagen alpha-1(VI) chain
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVD
KVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAV
KYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAK
HLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIK
NNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGM
KGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGP
KGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGA
PGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGD
EGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTK
GYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDII
MKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYA
GVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPN
NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS
QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASV
GSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTAL
ASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQ
EAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQT
VSRKVALG
Target Bioclass
Other
Family
Type VI collagen family
Subcellular location
Secreted, extracellular space, extracellular matrix
Function Collagen VI acts as a cell-binding protein.
Uniprot ID
P12109
Ensemble ID
ENST00000361866.8
HGNC ID
HGNC:2211
ChEMBL ID
CHEMBL2364188

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DA-P3
 Probe Info  		5.24  LDD0179  [1]
DBIA
 Probe Info  		C247(0.96); C248(0.96); C252(0.96); C604(0.95)  LDD0078  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
IPM
 Probe Info  		C252(0.00); C774(0.00)  LDD2156  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C169(1.31); C252(1.40); C604(1.28); C606(1.38)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C252(1.03); C606(1.44); C607(1.46); C609(1.03)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C604(1.21); C606(1.21); C607(0.91)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C604(1.24); C606(1.24); C607(0.90)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C604(1.16); C606(1.16); C607(1.07)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C604(1.49); C606(1.49); C607(1.34)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C604(1.21); C606(1.21); C607(1.08)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C604(1.34); C606(1.34); C607(1.22)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C604(1.16); C606(1.16); C607(1.11)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C604(0.96); C606(1.26); C607(0.58)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C604(1.54); C606(1.16); C607(1.56)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C604(1.27); C606(0.89); C607(1.59)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C252(0.92); C606(1.45); C607(1.41); C609(1.10)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C604(1.53); C606(1.23); C607(1.49)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C604(1.33); C606(1.12); C607(1.42)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C604(1.37); C606(1.20); C607(1.30)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C604(0.98); C606(1.11); C609(0.99)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C604(1.13); C606(1.11); C609(1.10)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C604(0.99); C606(1.02); C609(0.99)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C604(0.99); C606(1.09); C609(1.19)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C604(0.86); C606(1.19); C609(1.14)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C604(0.94); C606(1.05); C609(1.17)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C604(1.02); C606(1.23); C609(1.23)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C252(0.91); C606(1.21); C607(1.18); C609(1.08)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C604(1.07); C606(1.07); C609(1.03)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C604(0.98); C606(1.06); C609(0.89)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C604(1.30); C606(1.10); C609(1.10)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C604(0.92); C606(1.12); C609(0.92)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C604(0.97); C606(1.19); C609(1.10)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C604(1.16); C606(1.09); C609(1.08)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C604(1.15); C606(0.89); C609(0.85)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C604(0.99); C606(0.95); C609(0.97)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C606(0.89); C609(0.89)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C606(0.97); C609(0.97)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C606(1.12); C609(1.12)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C606(1.06); C609(1.06)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C606(1.07); C609(1.07)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C606(1.08); C609(1.08)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C606(1.20); C609(1.20)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C606(1.12); C609(1.12)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C606(1.16); C609(1.16)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C606(1.01); C609(1.01)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C606(1.37); C609(1.37)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C606(1.42); C609(1.42)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C252(1.18); C606(1.31); C607(1.24); C609(1.07)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C606(1.51); C609(1.51)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C606(1.29); C609(1.29)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C606(1.29); C609(1.29)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C604(1.05); C606(1.14); C607(1.04)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C606(1.15); C604(1.17); C607(1.38)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C606(1.07); C604(1.15); C607(1.35)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C607(1.08); C606(1.28); C604(1.44)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C604(1.19); C606(1.33); C607(1.44)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C607(1.53); C606(1.63); C604(1.63)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C607(1.04); C606(1.33); C604(1.48)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C252(1.02); C609(1.07); C607(1.25); C606(1.30)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C607(0.81); C606(1.01); C604(1.08)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C604(1.00); C606(1.11); C607(1.18)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C607(1.27); C606(1.34); C604(1.40)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C607(1.48); C606(1.63); C604(1.80)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C604(1.14); C606(1.19); C607(1.07)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C604(1.04); C606(0.98); C607(0.96)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C604(1.23); C606(1.14); C607(0.84)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C604(0.85); C606(0.83); C607(0.90)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C607(0.84); C252(0.87); C606(0.94); C604(1.13)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C252(0.93); C607(0.99); C606(0.99); C604(1.07)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C606(0.82); C607(0.84); C604(1.03); C609(1.03)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C609(1.37); C169(1.37); C604(1.38); C606(1.57)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C252(0.55); C607(0.58); C606(0.64); C604(0.73)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C607(0.68); C252(0.69); C606(0.75); C604(0.97)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C252(0.64); C607(0.79); C606(0.81); C604(1.22)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C252(0.83); C606(0.86); C607(0.95); C604(1.03)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C606(0.84); C607(0.85); C252(0.87); C604(0.98)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C607(0.88); C609(0.92); C606(0.96); C604(1.00)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C607(0.77); C606(1.07); C609(1.08); C604(1.20)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C607(1.04); C609(1.11); C606(1.21); C604(1.22)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C607(0.72); C609(1.00); C606(1.07); C252(1.07)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C607(0.79); C606(1.00); C609(1.02); C604(1.17)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C169(1.22); C607(1.45); C604(1.50); C252(1.65)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C607(0.79); C606(1.17); C609(1.20); C604(1.40)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C609(1.17); C607(1.19); C252(1.24); C606(1.29)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C607(1.20); C609(1.35); C606(1.54); C604(1.65)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C609(1.10); C607(1.23); C604(1.32); C606(1.35)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C607(0.72); C609(0.91); C606(1.24); C604(1.24)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C607(0.60); C604(0.75); C606(0.80); C609(0.96)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C607(0.64); C606(0.82); C604(0.83); C609(1.02)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C607(0.53); C604(0.70); C606(0.79); C609(0.89)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C607(0.69); C606(0.84); C604(1.04); C252(1.39)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C607(0.60); C604(0.88); C606(1.03); C252(1.16)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C169(1.22); C252(1.43); C607(1.69); C604(1.70)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C607(0.48); C606(0.93); C604(1.01); C252(1.39)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C609(0.77); C604(0.80); C607(0.83); C606(0.89)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C607(0.71); C604(0.89); C609(0.98); C252(1.02)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C607(0.72); C604(0.84); C609(0.90); C606(0.94)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C607(0.64); C604(0.76); C609(0.88); C606(0.91)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C607(0.56); C604(0.75); C609(0.90); C252(0.99)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C609(0.99); C252(1.00); C604(1.04); C607(1.09)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C609(0.90); C604(0.95); C606(0.98); C607(1.02)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C169(0.86); C606(0.91); C604(1.02); C607(1.04)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C609(0.90); C606(1.04); C604(1.06); C169(1.10)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C169(1.14); C607(1.66); C604(1.68); C606(1.74)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C609(0.89); C169(0.98); C606(0.98); C604(1.00)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C606(0.82); C169(0.83); C252(0.90); C609(0.91)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C606(0.79); C169(0.87); C609(0.93); C604(0.95)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C169(0.60); C606(0.80); C609(0.80); C604(0.86)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C169(0.76); C606(0.79); C609(0.92); C604(1.01)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C169(0.65); C609(0.94); C604(1.04); C607(1.06)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C169(0.56); C609(0.73); C606(0.78); C604(0.85)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C607(0.81); C606(1.34); C609(1.39); C252(1.98)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C607(0.74); C606(1.04); C609(1.10); C252(2.14)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C607(0.86); C606(1.58); C609(1.63); C252(1.91)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C252(0.79); C609(0.89); C606(1.05); C607(1.14)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C607(0.79); C606(1.30); C609(1.37); C252(1.93)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C607(0.97); C606(1.20); C609(1.20); C252(1.61)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C607(0.86); C606(1.23); C609(1.27); C252(2.21)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C607(0.56); C606(1.11); C609(1.16); C252(1.81)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C607(0.70); C606(1.42); C609(1.47); C252(2.78)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C607(0.98); C606(1.83); C609(1.84); C252(2.86)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C607(0.74); C606(1.69); C609(1.72); C252(2.44)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C607(0.75); C606(1.62); C609(1.64); C252(3.26)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C607(0.79); C606(0.81); C604(1.02); C609(1.07)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C606(0.85); C607(0.87); C604(0.94); C609(0.96)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C252(0.82); C609(1.03); C606(1.16); C607(1.24)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C252(0.87); C606(1.23); C607(1.31); C604(1.52)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C252(0.91); C606(1.17); C609(1.29); C607(1.31)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C252(0.97); C604(1.20); C609(1.21); C607(1.31)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C607(1.20); C606(1.27); C609(1.37); C604(1.50)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C606(1.22); C609(1.22); C607(1.22); C604(1.35)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C606(0.99); C607(1.00); C609(1.47); C604(1.53)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C606(0.98); C609(1.06); C607(1.14); C604(1.14)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C606(0.91); C607(0.92); C604(0.93); C609(0.99)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C607(0.94); C606(1.00); C609(1.05); C604(1.06)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C252(0.89); C607(1.19); C604(1.26); C609(1.27)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C252(0.51); C609(1.04); C607(1.13); C606(1.14)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C252(0.99); C609(1.10); C606(1.18); C604(1.25)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C252(0.79); C609(0.95); C604(1.05); C606(1.17)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C607(1.02); C606(1.04); C609(1.47); C252(1.50)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C169(1.37); C606(1.59); C609(1.65); C607(1.66)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C169(1.09); C609(1.17); C604(1.33); C607(1.41)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C169(1.12); C606(1.24); C252(1.32); C607(1.36)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C169(1.02); C606(1.26); C604(1.39); C252(1.41)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C169(0.95); C606(1.16); C604(1.18); C252(1.24)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C606(1.05); C169(1.08); C604(1.13); C607(1.21)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C606(1.12); C169(1.13); C607(1.25); C604(1.25)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C606(1.05); C604(1.22); C252(1.24); C607(1.32)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C169(1.24); C606(1.24); C609(1.31); C607(1.36)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C606(1.14); C604(1.27); C169(1.28); C607(1.34)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C604(1.03); C606(1.04); C252(1.04); C607(1.13)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C169(1.05); C252(1.10); C606(1.10); C604(1.18)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C606(0.96); C169(1.19); C607(1.20); C604(1.21)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C604(1.03); C606(1.03); C607(1.08); C169(1.17)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C169(1.22); C606(1.29); C604(1.40); C607(1.49)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C604(2.19); C606(2.19); C607(2.50)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C607(0.91); C604(1.22); C606(1.22)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C252(0.99); C606(1.26); C607(1.28); C609(0.97)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C252(0.91); C609(0.97); C607(1.32); C606(1.34)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C609(1.14); C252(1.52); C607(1.69); C606(1.75)  LDD0592  [2]
 LDCM0020  ARS-1620 HCC44 C247(0.96); C248(0.96); C252(0.96); C604(0.95)  LDD0078  [2]
 LDCM0367  CL1 HCT 116 C607(0.81); C604(1.02); C252(1.03); C606(1.10)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C606(1.06); C607(1.07); C609(1.38); C604(1.71)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C169(1.24); C604(1.45); C609(1.53); C606(1.59)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C609(0.87); C606(1.09); C252(1.14); C607(1.17)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C609(0.91); C252(1.05); C606(1.24); C607(1.41)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C252(0.67); C609(0.88); C606(0.93); C607(1.05)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C252(0.93); C609(0.96); C606(1.10); C607(1.10)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C604(1.14); C609(1.14); C606(1.26); C607(1.28)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C252(0.79); C606(1.06); C604(1.12); C609(1.12)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C604(1.15); C609(1.15); C607(1.20); C606(1.20)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C604(1.21); C609(1.21); C606(1.40); C607(1.43)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C252(1.01); C606(1.06); C607(1.12); C604(1.13)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C607(0.89); C604(1.15); C606(1.15); C609(1.19)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C604(1.16); C609(1.16); C606(1.22); C607(1.30)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C606(1.03); C252(1.05); C607(1.14); C604(1.20)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C607(0.92); C252(0.99); C609(1.05); C606(1.10)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C607(0.95); C609(1.12); C606(1.21); C604(1.33)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C607(1.19); C606(1.23); C609(1.26); C604(1.41)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C607(0.96); C609(1.15); C606(1.21); C604(1.40)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C609(1.07); C607(1.24); C604(1.31); C606(1.43)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C607(0.45); C604(1.01); C606(1.35); C252(1.37)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C607(0.83); C604(0.85); C609(0.86); C606(1.05)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C607(0.66); C604(0.80); C606(0.88); C609(0.94)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C607(1.04); C606(1.33); C609(1.48); C604(1.64)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C607(0.68); C604(0.79); C609(0.87); C606(0.91)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C609(0.94); C169(0.96); C606(1.08); C604(1.13)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C169(0.86); C606(0.90); C607(1.06); C604(1.15)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C169(0.64); C606(0.65); C609(0.97); C607(1.02)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C169(0.53); C606(0.71); C609(0.81); C604(0.96)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C607(0.87); C606(1.22); C252(1.23); C609(1.25)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C607(0.81); C252(1.25); C606(1.30); C609(1.33)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C607(0.80); C606(1.25); C609(1.29); C252(1.40)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C607(0.84); C606(1.43); C609(1.43); C252(2.19)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C606(1.07); C607(1.28); C252(1.48); C609(1.50)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C606(0.87); C609(1.23); C607(1.24); C252(1.56)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C607(1.00); C604(1.18); C606(1.22); C609(1.23)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C252(0.93); C604(1.10); C607(1.22); C609(1.30)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C609(0.88); C606(0.93); C607(1.00); C252(1.27)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C606(1.07); C609(1.07); C607(1.10); C252(1.37)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C606(1.10); C609(1.16); C607(1.23); C252(1.38)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C607(0.78); C606(0.83); C252(0.84); C604(0.89)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C606(1.03); C607(1.17); C609(1.23); C252(1.71)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C606(1.04); C609(1.10); C607(1.16); C252(1.90)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C607(1.34); C606(1.38); C609(1.45); C252(2.03)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C607(0.93); C606(1.03); C609(1.13); C252(1.29)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C606(1.11); C609(1.16); C607(1.21); C252(1.60)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C252(1.57); C606(1.19); C607(1.17); C609(1.26)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C252(1.22); C606(1.66); C607(1.50); C609(1.95)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C252(1.65); C606(1.24); C607(1.32); C609(1.36)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C252(1.38); C606(1.08); C607(1.17); C609(1.14)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C252(1.73); C606(1.00); C607(1.07); C609(1.17)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C252(0.92); C604(1.02); C606(0.89); C607(0.78)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C252(1.26); C606(1.09); C607(1.03); C609(1.39)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C169(0.87); C252(1.18); C604(0.97); C606(1.16)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C169(1.02); C252(1.24); C604(1.41); C606(1.75)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C169(1.17); C252(1.41); C604(1.01); C606(1.26)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C169(1.20); C252(1.37); C604(1.58); C606(1.91)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C169(0.89); C252(1.97); C604(1.39); C606(2.06)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C169(0.89); C252(1.71); C604(1.15); C606(1.82)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C169(0.91); C252(1.71); C604(1.20); C606(1.82)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C169(0.95); C252(1.98); C604(0.99); C606(1.32)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C252(1.26); C604(0.95); C606(1.14); C607(0.77)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C169(0.82); C252(1.54); C604(1.13); C606(1.26)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C169(0.77); C252(1.92); C604(1.15); C606(1.86)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C169(0.82); C252(1.98); C604(0.99); C606(1.58)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C169(1.00); C252(1.76); C604(1.31); C606(1.80)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C169(1.02); C252(1.54); C604(1.47); C606(1.65)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C169(0.81); C252(1.54); C604(1.47); C606(1.92)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C252(0.87); C604(1.09); C606(1.27); C607(1.16)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C252(0.80); C604(1.23); C606(1.40); C607(1.31)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C252(0.78); C604(1.32); C606(1.36); C607(1.26)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C252(0.84); C604(1.17); C606(1.43); C607(1.15)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C252(1.01); C604(0.87); C606(0.98); C607(0.88)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C252(1.01); C604(1.16); C606(1.34); C607(1.14)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C252(0.89); C604(1.11); C606(1.37); C607(1.23)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C252(0.96); C604(1.20); C606(1.30); C607(1.18)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C252(0.81); C604(1.04); C606(0.98); C607(1.21)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C252(0.80); C604(1.03); C606(0.78); C607(1.01)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C252(0.88); C604(1.05); C606(0.87); C607(1.01)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C252(1.01); C604(1.04); C606(0.88); C607(0.93)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C252(0.81); C604(1.15); C606(1.21); C607(1.10)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C252(0.73); C604(1.05); C606(0.98); C607(1.02)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C252(0.85); C604(1.02); C606(0.94); C607(1.02)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C252(1.18); C604(1.05); C606(1.01); C607(0.88)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C252(0.75); C604(1.31); C606(1.26); C607(1.32)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C252(1.08); C604(1.00); C606(1.12); C607(1.05)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C252(1.04); C604(1.01); C606(1.28); C607(1.03)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C252(1.16); C604(1.17); C606(1.33); C607(1.13)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C252(1.18); C604(1.32); C606(1.50); C607(1.30)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C252(1.18); C604(1.12); C606(1.16); C607(1.12)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C252(1.07); C604(1.50); C606(1.57); C607(1.40)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C252(1.09); C604(1.22); C606(1.25); C607(1.20)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C252(1.17); C604(1.28); C606(1.35); C607(1.29)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C252(1.03); C604(1.03); C606(1.10); C607(0.99)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C252(1.60); C604(1.85); C606(1.07); C607(1.29)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C252(0.88); C604(1.06); C606(1.08); C607(1.00)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C252(0.94); C604(1.15); C606(1.26); C607(1.10)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C252(0.97); C604(1.06); C606(1.16); C607(1.01)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C252(1.34); C604(1.24); C606(1.29); C607(1.18)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C252(0.91); C604(1.29); C606(1.26); C607(1.23)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C169(1.09); C252(1.19); C604(1.07); C606(1.18)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C169(0.89); C252(1.18); C604(1.24); C606(1.54)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C169(1.09); C252(1.09); C604(1.03); C606(1.74)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C169(1.17); C252(1.73); C604(1.15); C606(1.43)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C252(1.41); C604(0.95); C606(1.29); C607(0.91)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C169(1.34); C252(1.28); C604(1.39); C606(1.38)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C169(1.25); C252(1.36); C604(1.21); C606(2.11)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C169(1.44); C252(1.62); C604(1.23); C606(1.51)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C169(0.95); C252(1.90); C604(1.02); C606(0.99)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C169(0.98); C252(1.75); C604(1.20); C606(1.01)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C169(0.95); C252(1.47); C604(1.17); C606(1.10)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C169(1.07); C252(0.94); C604(1.20); C606(0.96)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C169(1.31); C252(1.27); C604(1.14); C606(1.19)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C169(1.35); C252(1.43); C604(1.07); C606(1.01)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C169(1.23); C252(1.78); C604(1.10); C606(1.41)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C252(0.97); C604(1.46); C606(1.16); C607(1.04)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C169(1.20); C252(1.67); C604(0.88); C606(0.90)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C169(1.39); C252(1.82); C604(1.12); C606(1.30)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C169(1.01); C252(1.49); C604(0.86); C606(0.89)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C169(0.93); C252(1.62); C604(1.12); C606(1.03)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C169(0.84); C252(2.00); C604(1.08); C606(1.15)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C169(0.99); C252(2.06); C604(1.27); C606(1.23)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C169(1.05); C252(1.83); C604(1.23); C606(1.33)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C169(1.34); C252(1.68); C604(1.28); C606(1.63)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C169(1.57); C252(1.99); C604(1.63); C606(1.49)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C169(1.32); C252(2.00); C604(1.32); C606(1.40)  LDD0811  [2]
 LDCM0027  Dopamine HEK-293T 5.24  LDD0179  [1]
 LDCM0495  E2913 HEK-293T C252(1.15)  LDD1698  [5]
 LDCM0468  Fragment33 HCT 116 C252(1.36); C604(1.33); C606(1.48); C607(1.28)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C169(0.64); C252(1.63); C604(1.23); C606(1.60)  LDD0744  [2]
 LDCM0022  KB02 HCT 116 C248(2.74); C252(2.74); C131(1.74)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C248(2.09); C252(2.09); C131(2.35)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C248(2.63); C252(2.63); C131(1.44)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C604(1.01); C606(1.01); C607(1.01)  LDD2173  [2]

References

1 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402