Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | AZ-5 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 2.5 uM | |||||
| Criteria | Quantification: Probe vs DMSO | |||||
| Quantitative Method |
LFQ
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Breast | ||||
| Disease Model | Invasive breast carcinoma [ICD-11:2C60] | |||||
| Model Name | Human invasive breast carcinoma cells (MCF-7) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00714 | 26S proteasome non-ATPase regulatory subunit 3 (PSMD3) | 10.0 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 10.0 | ||||
| LDTP14264 | Choline/ethanolaminephosphotransferase 1 (CEPT1) | 10.0 | ||||
| LDTP04327 | Cytosolic purine 5'-nucleotidase (NT5C2) | 10.0 | ||||
| LDTP02602 | Histidine--tRNA ligase, cytoplasmic (HARS1) | 10.0 | ||||
| LDTP05640 | Secernin-1 (SCRN1) | 10.0 | ||||
| LDTP07367 | Nucleoredoxin (NXN) | 6.8 | ||||
| LDTP09188 | Lysophosphatidylcholine acyltransferase 1 (LPCAT1) | 6.3 | ||||
| LDTP11297 | Guanine nucleotide-binding protein-like 3 (GNL3) | 4.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP06293 | Metal cation symporter ZIP14 (SLC39A14) | 10.0 | ||||
| LDTP14274 | Proton-coupled zinc antiporter SLC30A1 (SLC30A1) | 10.0 | ||||
| LDTP14173 | Sorting nexin-8 (SNX8) | 10.0 | ||||
| LDTP00970 | Gasdermin-E (GSDME) | 7.5 | ||||
| LDTP04013 | Neutral amino acid transporter A (SLC1A4) | 5.8 | ||||
| LDTP03839 | Nuclear pore glycoprotein p62 (NUP62) | 3.7 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00223 | 26S proteasome non-ATPase regulatory subunit 11 (PSMD11) | 10.0 | ||||
| LDTP02300 | Alpha-2-antiplasmin (SERPINF2) | 10.0 | ||||
| LDTP11682 | Polyadenylate-binding protein-interacting protein 1 (PAIP1) | 10.0 | ||||
| LDTP05424 | Keratin, type I cytoskeletal 17 (KRT17) | 5.0 | ||||
| LDTP04205 | Keratin, type II cytoskeletal 6C (KRT6C) | 4.2 | ||||
| LDTP02124 | Keratin, type I cytoskeletal 18 (KRT18) | 3.5 | ||||
| LDTP02305 | Keratin, type II cytoskeletal 7 (KRT7) | 2.7 | ||||
| LDTP02205 | Tubulin beta chain (TUBB) | 2.4 | ||||
| LDTP06809 | Tubulin beta-8 chain (TUBB8) | 2.4 | ||||
| LDTP05590 | Histone-binding protein RBBP4 (RBBP4) | 2.4 | ||||
| LDTP05076 | Tubulin beta-4B chain (TUBB4B) | 2.3 | ||||
| LDTP05898 | Sequestosome-1 (SQSTM1) | 2.1 | ||||