Details of the Target

General Information of Target

Target ID LDTP15986
Target Name Gametogenetin-binding protein 2 (GGNBP2)
Gene Name GGNBP2
Gene ID 79893
Synonyms
LCRG1; LZK1; ZNF403; Gametogenetin-binding protein 2; Laryngeal carcinoma-related protein 1; Protein ZNF403
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAKGGEALPQGSPAPVQDPHLIKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQ
LVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKRQHRAMGNECPAASVPTQGPSPGSLPQP
SSIYPADGPPAFSLGLLTGLSRLGLAYRGFPDQPSSLMRQHVSVPEFVTQLIDDPFIPGL
LSNTGLVRQLVLDNPHMQQLIQHNPEIGHILNNPEIMRQTLEFLRNPAMMQEMIRSQDRV
LSNLESIPGGYNVLCTMYTDIMDPMLNAVQEQFGGNPFATATTDNATTTTSQPSRMENCD
PLPNPWTSTHGGSGSRQGRQDGDQDAPDIRNRFPNFLGIIRLYDYLQQLHENPQSLGTYL
QGTASALSQSQEPPPSVNRVPPSSPSSQEPGSGQPLPEESVAIKGRSSCPAFLRYPTENS
TGQGGDQDGAGKSSTGHSTNLPDLVSGLGDSANRVPFAPLSFSPTAAIPGIPEPPWLPSP
AYPRSLRPDGMNPAPQLQDEIQPQLPLLMHLQAAMANPRALQALRQIEQGLQVLATEAPR
LLLWFMPCLAGTGSVAGGIESREDPLMSEDPLPNPPPEVFPALDSAELGFLSPPFLHMLQ
DLVSTNPQQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVEKLRQS
Target Bioclass
Other
Subcellular location
Cytoplasmic vesicle
Function May be involved in spermatogenesis.
Uniprot ID
Q9H3C7
Ensemble ID
ENST00000613102.5
HGNC ID
HGNC:19357

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCK81 SNV: p.R374C .
HCT116 SNV: p.D575G DBIA    Probe Info 
HEC1 SNV: p.R561Ter .
HEC1B SNV: p.R561Ter .
HT115 SNV: p.E285K .
KMRC3 Deletion: p.R561EfsTer66 .
MFE319 Insertion: p.F17LfsTer22
SNV: p.Q645Ter		 .
NCIH1993 SNV: p.C586F .
OCUG1 SNV: p.E184K DBIA    Probe Info 
P31FUJ SNV: p.C262Ter DBIA    Probe Info 
SG231 SNV: p.E256D DBIA    Probe Info 
SKNSH SNV: p.T29P .
TCCSUP SNV: p.E546Q .
TOV21G Deletion: p.K376NfsTer26 DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		9.21  LDD0402  [1]
DBIA
 Probe Info  		C461(1.30); C466(1.30); C687(1.12); C385(1.03)  LDD0078  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [3]
Lodoacetamide azide
 Probe Info  		C236(0.00); C128(0.00)  LDD0037  [3]
WYneN
 Probe Info  		N.A.  LDD0021  [4]
IPM
 Probe Info  		C243(0.00); C585(0.00); C554(0.00); C544(0.00)  LDD2156  [5]
TFBX
 Probe Info  		C252(0.00); C544(0.00); C554(0.00)  LDD0148  [6]
AOyne
 Probe Info  		14.10  LDD0443  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C128(0.85); C236(1.18); C243(1.11); C262(0.96)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C236(0.85); C262(1.13); C263(1.13); C385(0.76)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C128(0.50); C236(0.87); C243(0.79); C262(0.78)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C128(0.70); C236(0.97); C243(0.94); C262(0.88)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C128(0.55); C236(1.04); C243(0.82); C262(0.84)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C128(0.68); C236(1.03); C243(0.85); C262(0.92)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C128(0.58); C236(0.89); C243(0.86); C262(0.98)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C128(0.68); C236(0.99); C243(0.78); C262(0.84)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C128(0.68); C236(0.96); C243(0.70); C262(0.80)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C128(0.67); C236(0.95); C243(0.75); C262(0.81)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C128(0.72); C236(0.92); C243(1.00); C262(0.88)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C128(1.07); C236(0.98); C243(0.97); C262(1.01)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C236(0.86); C262(0.91); C263(0.91); C385(0.88)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C128(0.69); C236(0.96); C243(0.86); C262(0.83)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C128(0.68); C236(0.97); C243(0.93); C262(0.97)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C128(0.67); C236(1.03); C243(0.82); C262(0.97)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C128(0.80); C243(0.93); C262(1.11); C263(1.11)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C128(0.76); C243(1.04); C262(1.03); C263(1.03)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C128(0.90); C243(0.99); C262(1.25); C263(1.25)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C128(0.96); C243(1.04); C262(1.19); C263(1.19)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C128(1.22); C243(1.03); C262(1.10); C263(1.10)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C128(1.20); C243(1.05); C262(1.13); C263(1.13)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C128(1.14); C243(0.91); C262(1.19); C263(1.19)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C236(0.76); C262(0.92); C263(0.92); C385(0.84)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C128(0.90); C243(1.28); C262(1.25); C263(1.25)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C128(1.53); C243(1.07); C262(1.10); C263(1.10)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C128(0.96); C243(1.08); C262(1.04); C263(1.04)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C128(1.30); C243(1.19); C262(1.19); C263(1.19)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C128(1.09); C243(0.95); C262(1.06); C263(1.06)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C128(0.82); C243(1.09); C262(0.97); C263(0.97)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C128(0.89); C243(0.92); C262(1.17); C263(1.17)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C128(1.07); C243(0.84); C262(1.31); C263(1.31)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C128(1.06); C262(1.08); C263(1.08); C385(1.42)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C128(0.74); C262(1.06); C263(1.06); C385(1.26)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C128(0.81); C262(1.09); C263(1.09); C385(1.64)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C128(0.81); C262(1.00); C263(1.00); C385(1.25)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C128(1.27); C262(1.00); C263(1.00); C385(1.02)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C128(0.89); C262(1.06); C263(1.06); C385(1.44)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C128(0.91); C262(0.98); C263(0.98); C385(1.63)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C128(1.13); C262(1.09); C263(1.09); C385(1.79)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C128(1.01); C262(0.97); C263(0.97); C385(0.93)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C128(1.27); C262(0.97); C263(0.97); C385(0.91)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C128(1.21); C262(0.96); C263(0.96); C385(1.48)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C128(1.22); C262(0.97); C263(0.97); C385(0.86)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C236(0.89); C262(1.10); C263(1.10); C385(0.79)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C128(0.90); C262(0.97); C263(0.97); C385(1.17)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C128(1.02); C262(1.02); C263(1.02); C385(1.05)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C128(1.15); C262(0.96); C263(0.96); C385(0.71)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C128(1.04); C236(1.25); C243(0.80); C262(1.19)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C128(0.87); C687(0.91); C385(0.92); C387(0.92)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C263(0.91); C385(0.92); C387(0.92); C585(0.96)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C243(0.75); C128(1.00); C385(1.01); C387(1.01)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C243(0.79); C128(0.91); C385(0.93); C387(0.93)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C263(0.79); C243(0.89); C687(0.98); C385(1.01)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C263(0.98); C385(1.01); C387(1.01); C687(1.12)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C687(0.76); C385(0.86); C387(0.86); C236(0.87)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C586(0.96); C243(0.98); C385(0.99); C387(0.99)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C128(0.92); C687(0.94); C415(0.95); C262(0.98)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C385(0.92); C387(0.92); C415(0.97); C243(1.01)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C263(0.94); C385(0.98); C387(0.98); C243(1.06)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C128(1.23); C236(1.70); C243(0.97); C262(0.93)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C128(1.33); C236(1.41); C243(0.92); C262(1.09)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C128(1.00); C236(1.20); C243(1.20); C262(0.95)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C128(0.70); C236(1.47); C243(0.77); C262(1.18)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C687(0.77); C243(0.84); C385(0.98); C387(0.98)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C687(0.70); C243(0.91); C262(1.06); C263(1.06)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C687(0.72); C243(0.88); C415(1.01); C554(1.05)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C585(0.73); C586(0.73); C385(0.89); C387(0.89)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C687(0.57); C243(0.84); C554(1.03); C415(1.06)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C687(0.71); C262(0.95); C263(0.95); C128(0.95)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C687(0.70); C243(0.77); C415(1.01); C262(1.02)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C687(0.40); C243(0.84); C554(0.93); C128(0.95)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C687(0.63); C243(0.83); C554(0.91); C385(0.93)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C415(0.77); C585(0.83); C586(0.83); C262(0.90)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C415(0.73); C385(0.95); C387(0.95); C262(0.97)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C128(0.90); C415(0.96); C585(1.05); C586(1.05)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C415(0.68); C385(0.84); C387(0.84); C128(1.00)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C128(1.09); C262(1.09); C263(1.09); C415(1.09)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C585(0.70); C586(0.70); C687(0.87); C243(0.89)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C554(1.02); C128(1.04); C385(1.07); C387(1.07)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C385(0.83); C387(0.83); C415(0.86); C128(0.97)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C415(0.89); C385(0.93); C387(0.93); C128(1.04)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C415(0.94); C128(1.03); C385(1.13); C387(1.13)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C128(0.91); C415(1.04); C385(1.04); C387(1.04)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C262(0.82); C263(0.82); C554(0.82); C243(0.91)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C262(0.88); C263(0.88); C554(0.96); C243(1.00)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C554(0.90); C262(0.96); C263(0.96); C243(0.98)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C554(0.89); C262(0.98); C263(0.98); C128(1.16)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C262(0.95); C263(0.95); C243(1.05); C554(1.05)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C554(0.80); C243(0.85); C415(0.88); C385(0.90)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C243(1.07); C554(1.18); C385(1.26); C387(1.26)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C262(1.09); C263(1.09); C554(1.11); C128(1.26)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C554(1.01); C128(1.17); C262(1.20); C263(1.20)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C262(1.04); C263(1.04); C243(1.10); C128(1.17)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C554(1.11); C585(1.14); C586(1.14); C262(1.16)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C585(1.13); C586(1.13); C262(1.24); C263(1.24)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C585(0.78); C586(0.78); C262(0.89); C263(0.89)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C585(0.87); C586(0.87); C554(0.87); C128(0.99)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C585(0.83); C586(0.83); C262(0.91); C263(0.91)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C554(1.00); C243(1.26); C128(1.31); C262(1.33)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C585(0.73); C586(0.73); C687(0.78); C554(0.80)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C243(0.84); C554(0.98); C128(1.07); C262(1.29)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C243(0.65); C585(0.76); C586(0.76); C262(0.78)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C585(0.96); C586(0.96); C243(0.98); C128(1.06)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C243(0.73); C554(0.90); C262(1.11); C263(1.11)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C243(0.94); C554(0.99); C128(1.11); C262(1.28)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C554(1.16); C243(1.21); C262(1.31); C263(1.31)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C554(1.05); C243(1.23); C128(1.43); C262(1.54)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C385(1.09); C387(1.09); C554(1.22); C128(1.36)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C128(1.02); C262(1.11); C263(1.11); C385(1.19)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C128(0.93); C262(0.94); C263(0.94); C385(0.97)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C687(0.74); C385(0.83); C387(0.83); C585(0.84)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C128(0.89); C262(1.07); C263(1.07); C385(1.15)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C585(0.91); C586(0.91); C385(0.92); C387(0.92)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C128(0.96); C262(0.98); C263(0.98); C243(1.07)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C128(0.89); C585(0.92); C586(0.92); C385(0.97)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C585(1.07); C586(1.07); C262(1.13); C263(1.13)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C585(0.35); C586(0.35); C128(1.10); C262(1.16)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C585(0.34); C586(0.34); C554(1.00); C385(1.04)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C585(0.40); C586(0.40); C262(0.88); C263(0.88)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C554(0.65); C385(0.88); C387(0.88); C585(0.95)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C554(0.70); C385(0.98); C387(0.98); C585(0.99)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C385(0.72); C387(0.72); C585(0.81); C586(0.81)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C554(0.75); C243(0.78); C128(1.09); C385(1.12)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C554(0.71); C243(0.79); C585(0.82); C586(0.82)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C243(0.77); C554(0.80); C585(0.97); C586(0.97)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C554(0.79); C243(0.94); C385(1.11); C387(1.11)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C554(0.81); C385(0.87); C387(0.87); C243(1.13)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C554(0.79); C243(0.91); C262(1.32); C263(1.32)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C554(0.79); C243(0.89); C385(0.90); C387(0.90)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C554(0.73); C385(1.02); C387(1.02); C262(1.08)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C554(0.65); C262(0.85); C263(0.85); C585(0.96)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C554(0.68); C585(0.92); C586(0.92); C262(1.03)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C687(0.78); C385(0.80); C387(0.80); C585(0.86)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C554(0.89); C385(0.93); C387(0.93); C243(0.98)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C554(0.62); C243(0.77); C262(0.87); C263(0.87)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C554(0.78); C243(0.78); C385(0.80); C387(0.80)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C385(1.30); C387(1.30); C687(1.33); C585(1.42)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C385(1.21); C387(1.21); C415(1.44); C243(1.48)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C415(1.02); C687(1.08); C385(1.09); C387(1.09)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C415(0.95); C687(1.09); C585(1.15); C586(1.15)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C415(0.89); C687(0.99); C385(1.01); C387(1.01)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C415(1.05); C385(1.21); C387(1.21); C687(1.21)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C687(1.01); C415(1.14); C385(1.16); C387(1.16)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C243(0.70); C415(0.78); C385(1.16); C387(1.16)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C687(1.03); C243(1.09); C385(1.44); C387(1.44)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C687(1.04); C243(1.08); C385(1.36); C387(1.36)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C243(0.90); C415(0.97); C687(1.03); C385(1.13)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C243(0.70); C687(0.80); C415(1.06); C585(1.07)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C243(0.94); C415(1.01); C687(1.04); C385(1.07)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C687(0.75); C243(0.80); C385(1.16); C387(1.16)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C243(0.85); C687(1.20); C415(1.27); C385(1.42)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C128(0.66); C262(0.87); C263(0.87); C385(0.95)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C128(0.59); C262(0.80); C263(0.80); C243(0.88)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C236(0.82); C262(1.14); C263(1.14); C385(0.82)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C385(0.74); C387(0.74); C236(0.82); C262(1.05)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C687(0.80); C236(0.95); C385(1.01); C387(1.01)  LDD0592  [2]
 LDCM0156  Aniline NCI-H1299 13.30  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C461(1.30); C466(1.30); C687(1.12); C385(1.03)  LDD0078  [2]
 LDCM0367  CL1 HCT 116 C243(0.51); C585(0.85); C586(0.85); C415(0.89)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C415(0.89); C243(0.95); C585(1.06); C586(1.06)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C585(0.74); C586(0.74); C262(0.95); C263(0.95)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C687(0.76); C385(0.90); C387(0.90); C236(0.91)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C385(0.74); C387(0.74); C687(0.76); C585(0.90)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C385(0.70); C387(0.70); C236(0.76); C687(0.77)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C385(0.76); C387(0.76); C585(0.77); C586(0.77)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C687(0.15); C415(0.84); C243(0.87); C128(0.93)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C687(0.66); C415(0.81); C128(1.01); C262(1.03)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C687(0.66); C415(0.90); C128(1.04); C554(1.17)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C687(0.55); C415(0.80); C243(0.85); C128(1.01)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C687(0.70); C415(1.00); C243(1.01); C128(1.03)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C415(0.83); C243(0.94); C262(1.09); C263(1.09)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C687(0.57); C415(0.90); C128(1.01); C262(1.02)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C687(0.69); C243(0.82); C128(0.95); C415(1.03)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C554(0.80); C585(0.91); C586(0.91); C128(0.92)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C385(0.93); C387(0.93); C128(0.97); C415(1.19)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C128(0.84); C554(0.94); C262(0.99); C263(0.99)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C128(0.90); C262(0.94); C263(0.94); C385(0.98)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C128(0.89); C415(1.00); C554(1.01); C385(1.08)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C385(1.07); C387(1.07); C128(1.18); C585(1.24)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C554(0.85); C243(0.99); C128(1.14); C385(1.19)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C243(1.06); C262(1.09); C263(1.09); C128(1.17)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C415(1.00); C243(1.06); C585(1.28); C586(1.28)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C554(0.93); C262(0.95); C263(0.95); C243(1.13)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C243(0.83); C554(1.14); C128(1.14); C585(1.42)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C585(0.59); C586(0.59); C262(0.99); C263(0.99)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C243(0.89); C128(1.03); C262(1.18); C263(1.18)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C128(0.97); C262(1.11); C263(1.11); C243(1.12)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C585(0.75); C586(0.75); C385(0.83); C387(0.83)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C128(0.76); C385(0.89); C387(0.89); C554(0.99)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C385(0.83); C387(0.83); C585(0.85); C586(0.85)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C262(1.00); C263(1.00); C385(1.09); C387(1.09)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C243(0.82); C415(0.95); C554(1.20); C262(1.20)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C385(0.95); C387(0.95); C415(0.96); C554(1.06)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C415(0.69); C243(0.69); C385(1.23); C387(1.23)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C554(0.77); C687(0.82); C243(1.16); C385(1.32)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C687(0.76); C262(0.77); C263(0.77); C554(0.89)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C687(0.78); C262(0.86); C263(0.86); C554(0.87)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C687(0.83); C262(0.88); C263(0.88); C554(1.13)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C243(0.60); C585(0.89); C586(0.89); C385(0.97)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C687(0.83); C554(1.01); C585(1.40); C586(1.40)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C262(0.82); C263(0.82); C687(0.83); C243(1.04)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C687(0.78); C554(0.79); C262(0.88); C263(0.88)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C554(0.82); C687(0.92); C262(0.98); C263(0.98)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C687(0.75); C262(0.85); C263(0.85); C554(0.95)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C243(1.06); C262(0.97); C263(0.97); C385(1.64)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C243(1.16); C262(0.94); C263(0.94); C385(1.38)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C243(1.02); C262(1.24); C263(1.24); C385(1.51)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C243(0.86); C262(0.92); C263(0.92); C385(1.45)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C243(1.59); C262(0.95); C263(0.95); C385(1.70)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C243(1.10); C262(1.01); C263(1.01); C385(1.17)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C243(1.05); C262(1.24); C263(1.24); C385(1.22)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C243(1.05); C262(1.03); C263(1.03); C415(0.84)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C243(1.24); C262(1.02); C263(1.02); C415(0.85)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C243(1.33); C262(1.36); C263(1.36); C415(1.06)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C243(1.60); C262(1.63); C263(1.63); C415(1.04)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C243(1.29); C262(1.21); C263(1.21); C415(1.19)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C243(1.27); C262(1.35); C263(1.35); C415(1.04)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C243(1.67); C262(1.41); C263(1.41); C415(0.98)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C243(1.32); C262(1.19); C263(1.19); C415(1.04)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C243(1.03); C262(1.08); C263(1.08); C385(1.22)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C243(1.10); C262(1.27); C263(1.27); C415(0.79)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C243(1.21); C262(1.17); C263(1.17); C415(0.94)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C243(1.34); C262(1.72); C263(1.72); C415(0.94)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C243(1.68); C262(1.35); C263(1.35); C415(0.90)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C243(1.42); C262(1.26); C263(1.26); C415(0.94)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C243(1.49); C262(1.29); C263(1.29); C415(0.80)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C128(0.77); C236(0.68); C243(1.21); C262(0.97)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C128(0.69); C236(0.71); C243(1.02); C262(0.83)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C128(0.73); C236(0.68); C243(1.00); C262(0.85)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C128(0.95); C236(0.84); C243(1.00); C262(0.95)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C243(0.78); C262(1.05); C263(1.05); C385(1.14)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C128(0.80); C236(0.87); C243(0.88); C262(0.84)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C128(0.81); C236(0.82); C243(1.00); C262(0.85)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C128(1.00); C236(0.80); C243(1.10); C262(1.08)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C128(0.70); C236(0.67); C243(1.27); C262(0.93)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C128(0.80); C236(0.72); C243(1.28); C262(0.89)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C128(0.88); C236(0.72); C243(1.09); C262(0.96)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C128(0.74); C236(0.77); C243(1.26); C262(0.85)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C128(0.64); C236(0.77); C243(1.23); C262(0.75)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C128(1.01); C236(0.83); C243(1.14); C262(0.88)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C128(0.90); C236(1.00); C243(1.18); C262(0.90)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C243(0.71); C262(1.10); C263(1.10); C385(1.16)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C128(0.94); C236(0.86); C243(1.01); C262(0.85)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C236(0.97); C243(0.90); C262(1.10); C263(1.10)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C236(0.98); C243(0.83); C262(1.05); C263(1.05)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C236(1.02); C243(1.14); C262(1.17); C263(1.17)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C236(1.00); C243(0.66); C262(1.44); C263(1.44)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C236(0.88); C243(0.66); C262(1.25); C263(1.25)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C236(1.23); C243(0.53); C262(1.45); C263(1.45)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C236(1.04); C243(0.88); C262(1.46); C263(1.46)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C236(1.00); C243(0.72); C262(1.27); C263(1.27)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C236(0.82); C243(1.18); C262(1.00); C263(1.00)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C243(0.86); C262(1.09); C263(1.09); C385(1.33)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C236(1.00); C243(1.10); C262(1.25); C263(1.25)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C236(1.02); C243(0.98); C262(1.25); C263(1.25)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C236(1.03); C243(1.12); C262(1.27); C263(1.27)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C236(0.91); C243(0.98); C262(1.19); C263(1.19)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C236(0.93); C243(1.01); C262(1.31); C263(1.31)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C128(0.98); C262(0.95); C263(0.95); C385(0.98)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C128(1.08); C262(0.98); C263(0.98); C385(1.15)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C128(1.04); C262(0.98); C263(0.98); C385(1.10)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C128(1.04); C262(0.92); C263(0.92); C385(1.16)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C243(1.08); C262(1.13); C263(1.13); C385(1.81)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C128(1.18); C262(1.01); C263(1.01); C385(0.95)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C128(0.98); C262(1.14); C263(1.14); C385(1.13)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C128(1.02); C262(1.14); C263(1.14); C385(1.07)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C128(0.88); C262(0.88); C263(0.88); C385(1.12)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C128(0.95); C262(1.51); C263(1.51); C385(1.08)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C128(1.12); C262(1.13); C263(1.13); C385(1.03)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C128(0.78); C262(1.05); C263(1.05); C385(1.12)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C128(1.02); C262(0.94); C263(0.94); C385(1.20)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C128(1.16); C262(1.25); C263(1.25); C385(1.17)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C128(1.00); C262(1.08); C263(1.08); C385(1.14)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C243(1.06); C262(1.07); C263(1.07); C385(1.19)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C128(1.13); C262(1.12); C263(1.12); C385(1.22)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C128(0.86); C236(1.17); C243(1.18); C262(0.95)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C128(0.77); C236(1.05); C243(1.09); C262(1.04)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C128(1.01); C236(0.98); C243(0.75); C262(0.85)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C128(0.88); C236(1.23); C243(1.12); C262(0.80)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C128(0.85); C236(1.13); C243(0.93); C262(1.06)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C128(0.97); C236(1.06); C243(0.96); C262(0.83)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C128(0.84); C236(1.23); C243(0.94); C262(0.89)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C128(0.86); C236(1.17); C243(0.86); C262(1.13)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C128(1.05); C236(1.16); C243(0.85); C262(0.96)  LDD0811  [2]
 LDCM0468  Fragment33 HCT 116 C236(0.84); C243(0.87); C262(1.17); C263(1.17)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C243(1.47); C262(1.45); C263(1.45); C415(0.98)  LDD0744  [2]
 LDCM0022  KB02 HCT 116 C585(3.25); C586(3.25); C243(2.25); C415(1.81)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C585(1.66); C586(1.66); C243(2.96); C415(1.66)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C585(3.12); C586(3.12); C243(2.01); C415(1.83)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C516(1.32); C519(1.32); C385(1.32); C387(1.32)  LDD2173  [2]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264