Details of the Target

General Information of Target

Target ID LDTP13066
Target Name TBC1 domain family member 14 (TBC1D14)
Gene Name TBC1D14
Gene ID 57533
Synonyms
KIAA1322; TBC1 domain family member 14
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKLTSEKLPKNPFYASVSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTL
AYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVDYMKKI
LDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLG
LYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAER
GNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTDCLPEFIGRGMAMAS
FYHARCLQLGLGITRDETTAKHYYSKACRLNPALADELHSLLIRQRI
Target Bioclass
Other
Subcellular location
Golgi apparatus, cis-Golgi network
Function
Plays a role in the regulation of starvation-induced autophagosome formation. Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy.
Uniprot ID
Q9P2M4
Ensemble ID
ENST00000409757.9
HGNC ID
HGNC:29246

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCC15 SNV: p.D136Y .
LN18 SNV: p.L178F .
LS180 SNV: p.S151I .
NCIH1793 SNV: p.M633I .
SKMEL2 SNV: p.V410A .
WM2664 Insertion: . .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C601(0.89)  LDD0532  [1]
IPM
 Probe Info  		N.A.  LDD2156  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C601(0.89)  LDD1093  [1]
 LDCM0215  AC10 HCT 116 C601(0.89)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C601(0.39)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C601(0.51)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C601(0.40)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C601(0.47)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C601(0.49)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C601(0.50)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C601(0.40)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C601(0.47)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C601(0.49)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C601(0.56)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C601(0.95)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C601(0.46)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C601(0.57)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C601(0.36)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C601(1.05)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C601(0.92)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C601(0.96)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C601(0.88)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C601(1.27)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C601(1.16)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C601(1.05)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C601(1.09)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C601(1.10)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C601(1.05)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C601(1.02)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C601(0.90)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C601(1.04)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C601(1.10)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C601(1.29)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C601(0.90)  LDD0562  [1]
 LDCM0246  AC128 HCT 116 C601(0.96)  LDD0563  [1]
 LDCM0247  AC129 HCT 116 C601(1.03)  LDD0564  [1]
 LDCM0249  AC130 HCT 116 C601(0.89)  LDD0566  [1]
 LDCM0250  AC131 HCT 116 C601(0.98)  LDD0567  [1]
 LDCM0251  AC132 HCT 116 C601(0.85)  LDD0568  [1]
 LDCM0252  AC133 HCT 116 C601(0.93)  LDD0569  [1]
 LDCM0253  AC134 HCT 116 C601(0.95)  LDD0570  [1]
 LDCM0254  AC135 HCT 116 C601(1.01)  LDD0571  [1]
 LDCM0255  AC136 HCT 116 C601(0.92)  LDD0572  [1]
 LDCM0256  AC137 HCT 116 C601(0.78)  LDD0573  [1]
 LDCM0257  AC138 HCT 116 C601(0.83)  LDD0574  [1]
 LDCM0258  AC139 HCT 116 C601(0.82)  LDD0575  [1]
 LDCM0259  AC14 HCT 116 C601(0.93)  LDD0576  [1]
 LDCM0260  AC140 HCT 116 C601(0.97)  LDD0577  [1]
 LDCM0261  AC141 HCT 116 C601(0.82)  LDD0578  [1]
 LDCM0262  AC142 HCT 116 C601(0.86)  LDD0579  [1]
 LDCM0263  AC143 HCT 116 C601(0.99)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C601(0.90)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C601(0.77)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C601(0.72)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C601(0.74)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C601(0.90)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C601(0.77)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C601(0.92)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C601(0.86)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C601(0.87)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C601(0.93)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C601(0.94)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C601(0.79)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C601(0.73)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C601(0.88)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C601(1.13)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C601(0.87)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C601(0.81)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C601(0.87)  LDD0595  [1]
 LDCM0279  AC2 PaTu 8988t C601(0.78)  LDD1158  [1]
 LDCM0280  AC20 HCT 116 C601(0.85)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C601(0.66)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C601(0.96)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C601(0.73)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C601(0.82)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C601(1.10)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C601(0.97)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C601(0.91)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C601(0.92)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C601(1.01)  LDD0606  [1]
 LDCM0290  AC3 PaTu 8988t C601(0.68)  LDD1169  [1]
 LDCM0291  AC30 HCT 116 C601(1.06)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C601(0.96)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C601(0.95)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C601(1.00)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C601(1.01)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C601(1.14)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C601(0.79)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C601(1.08)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C601(1.03)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C601(1.12)  LDD0617  [1]
 LDCM0301  AC4 PaTu 8988t C601(0.70)  LDD1180  [1]
 LDCM0302  AC40 HCT 116 C601(1.22)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C601(0.96)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C601(1.16)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C601(1.12)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C601(1.04)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C601(1.26)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C601(0.97)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C601(0.96)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C601(0.98)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C601(0.98)  LDD0628  [1]
 LDCM0312  AC5 PaTu 8988t C601(0.72)  LDD1191  [1]
 LDCM0313  AC50 HCT 116 C601(0.99)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C601(1.15)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C601(1.05)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C601(0.98)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C601(0.97)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C601(0.93)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C601(1.08)  LDD0636  [1]
 LDCM0320  AC57 PaTu 8988t C601(1.01)  LDD1199  [1]
 LDCM0321  AC58 PaTu 8988t C601(1.03)  LDD1200  [1]
 LDCM0322  AC59 PaTu 8988t C601(0.97)  LDD1201  [1]
 LDCM0323  AC6 HCT 116 C601(1.06)  LDD0640  [1]
 LDCM0324  AC60 PaTu 8988t C601(1.23)  LDD1203  [1]
 LDCM0325  AC61 PaTu 8988t C601(1.12)  LDD1204  [1]
 LDCM0326  AC62 PaTu 8988t C601(1.15)  LDD1205  [1]
 LDCM0327  AC63 PaTu 8988t C601(0.89)  LDD1206  [1]
 LDCM0328  AC64 PaTu 8988t C601(0.94)  LDD1207  [1]
 LDCM0329  AC65 PaTu 8988t C601(0.99)  LDD1208  [1]
 LDCM0330  AC66 PaTu 8988t C601(1.14)  LDD1209  [1]
 LDCM0331  AC67 PaTu 8988t C601(0.94)  LDD1210  [1]
 LDCM0334  AC7 HCT 116 C601(1.03)  LDD0651  [1]
 LDCM0345  AC8 HCT 116 C601(0.94)  LDD0662  [1]
 LDCM0349  AC83 HCT 116 C601(1.07)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C601(0.93)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C601(0.83)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C601(0.97)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C601(0.85)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C601(0.92)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C601(0.83)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C601(1.12)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C601(0.99)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C601(1.01)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C601(0.89)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C601(0.86)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C601(0.78)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C601(0.86)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C601(0.96)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C601(0.47)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C601(0.50)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C601(1.02)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C601(1.01)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C601(0.96)  LDD0592  [1]
 LDCM0367  CL1 PaTu 8988t C390(0.66)  LDD1246  [1]
 LDCM0368  CL10 PaTu 8988t C390(1.03)  LDD1247  [1]
 LDCM0369  CL100 PaTu 8988t C601(0.73)  LDD1248  [1]
 LDCM0370  CL101 HCT 116 C601(0.94)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C601(0.98)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C601(1.13)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C601(1.13)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C601(0.71)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C601(0.76)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C601(0.81)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C601(0.85)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C601(0.71)  LDD0695  [1]
 LDCM0379  CL11 PaTu 8988t C390(1.18)  LDD1258  [1]
 LDCM0380  CL110 HCT 116 C601(0.74)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C601(0.74)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C601(1.09)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C601(0.93)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C601(0.95)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C601(0.88)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C601(1.08)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C601(1.31)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C601(1.14)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C601(1.04)  LDD0706  [1]
 LDCM0390  CL12 PaTu 8988t C390(0.69)  LDD1269  [1]
 LDCM0391  CL120 HCT 116 C601(1.12)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C601(1.20)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C601(0.86)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C601(1.02)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C601(1.06)  LDD0712  [1]
 LDCM0396  CL125 PaTu 8988t C601(1.12)  LDD1275  [1]
 LDCM0397  CL126 PaTu 8988t C601(1.18)  LDD1276  [1]
 LDCM0398  CL127 PaTu 8988t C601(1.32)  LDD1277  [1]
 LDCM0399  CL128 PaTu 8988t C601(1.14)  LDD1278  [1]
 LDCM0400  CL13 PaTu 8988t C390(1.19)  LDD1279  [1]
 LDCM0401  CL14 PaTu 8988t C390(1.55)  LDD1280  [1]
 LDCM0402  CL15 PaTu 8988t C390(0.88)  LDD1281  [1]
 LDCM0407  CL2 PaTu 8988t C390(0.98)  LDD1286  [1]
 LDCM0411  CL23 HEK-293T C219(1.04)  LDD1615  [3]
 LDCM0412  CL24 HEK-293T C219(1.12)  LDD1616  [3]
 LDCM0413  CL25 HEK-293T C390(0.91)  LDD1617  [3]
 LDCM0414  CL26 HEK-293T C429(0.98)  LDD1618  [3]
 LDCM0418  CL3 PaTu 8988t C390(1.13)  LDD1297  [1]
 LDCM0420  CL31 HCT 116 C601(0.70)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C601(0.58)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C601(0.56)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C601(0.71)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C601(0.72)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C601(0.70)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C601(0.66)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C601(0.75)  LDD0745  [1]
 LDCM0429  CL4 PaTu 8988t C390(1.15)  LDD1308  [1]
 LDCM0430  CL40 HCT 116 C601(0.80)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C601(0.66)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C601(0.78)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C601(0.67)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C601(0.63)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C601(0.80)  LDD0752  [1]
 LDCM0436  CL46 PaTu 8988t C390(1.22)  LDD1315  [1]
 LDCM0437  CL47 PaTu 8988t C390(1.40)  LDD1316  [1]
 LDCM0438  CL48 PaTu 8988t C390(1.30)  LDD1317  [1]
 LDCM0439  CL49 PaTu 8988t C390(1.35)  LDD1318  [1]
 LDCM0440  CL5 PaTu 8988t C390(1.60)  LDD1319  [1]
 LDCM0441  CL50 PaTu 8988t C390(1.18)  LDD1320  [1]
 LDCM0442  CL51 PaTu 8988t C390(1.28)  LDD1321  [1]
 LDCM0443  CL52 PaTu 8988t C390(1.41)  LDD1322  [1]
 LDCM0444  CL53 PaTu 8988t C390(1.34)  LDD1323  [1]
 LDCM0445  CL54 PaTu 8988t C390(1.18)  LDD1324  [1]
 LDCM0446  CL55 PaTu 8988t C390(1.62)  LDD1325  [1]
 LDCM0447  CL56 PaTu 8988t C390(1.31)  LDD1326  [1]
 LDCM0448  CL57 PaTu 8988t C390(1.54)  LDD1327  [1]
 LDCM0449  CL58 PaTu 8988t C390(1.31)  LDD1328  [1]
 LDCM0450  CL59 PaTu 8988t C390(1.40)  LDD1329  [1]
 LDCM0451  CL6 PaTu 8988t C390(1.39)  LDD1330  [1]
 LDCM0452  CL60 PaTu 8988t C390(1.28)  LDD1331  [1]
 LDCM0453  CL61 HCT 116 C601(0.93)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C601(1.05)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C601(0.83)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C601(0.82)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C601(1.05)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C601(0.79)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C601(0.91)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C601(0.95)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C601(0.79)  LDD0778  [1]
 LDCM0462  CL7 PaTu 8988t C390(1.48)  LDD1341  [1]
 LDCM0463  CL70 HCT 116 C601(0.75)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C601(0.89)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C601(0.98)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C601(0.92)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C601(0.85)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C601(0.74)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C601(0.75)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C601(0.79)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C601(0.91)  LDD0789  [1]
 LDCM0473  CL8 PaTu 8988t C390(1.27)  LDD1352  [1]
 LDCM0474  CL80 HCT 116 C601(0.83)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C601(0.92)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C601(0.78)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C601(0.86)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C601(1.14)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C601(0.87)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C601(0.99)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C601(0.72)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C601(1.02)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C601(1.26)  LDD0800  [1]
 LDCM0484  CL9 PaTu 8988t C390(0.94)  LDD1363  [1]
 LDCM0485  CL90 HCT 116 C601(1.26)  LDD0802  [1]
 LDCM0486  CL91 PaTu 8988t C601(0.86)  LDD1365  [1]
 LDCM0487  CL92 PaTu 8988t C601(0.81)  LDD1366  [1]
 LDCM0488  CL93 PaTu 8988t C601(0.82)  LDD1367  [1]
 LDCM0489  CL94 PaTu 8988t C601(0.76)  LDD1368  [1]
 LDCM0490  CL95 PaTu 8988t C601(0.64)  LDD1369  [1]
 LDCM0491  CL96 PaTu 8988t C601(0.72)  LDD1370  [1]
 LDCM0492  CL97 PaTu 8988t C601(0.82)  LDD1371  [1]
 LDCM0493  CL98 PaTu 8988t C601(0.72)  LDD1372  [1]
 LDCM0494  CL99 PaTu 8988t C601(0.69)  LDD1373  [1]
 LDCM0468  Fragment33 HCT 116 C601(0.89)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C601(0.82)  LDD0744  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Serine/threonine-protein kinase ULK1 (ULK1) Ser/Thr protein kinase family O75385
Ras-related protein Rab-11B (RAB11B) Rab family Q15907
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Nuclear RNA export factor 1 (NXF1) NXF family Q9UBU9

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402