Details of the Target

General Information of Target

Target ID LDTP11468
Target Name RanBP-type and C3HC4-type zinc finger-containing protein 1 (RBCK1)
Gene Name RBCK1
Gene ID 10616
Synonyms
C20orf18; RNF54; UBCE7IP3; XAP3; XAP4; RanBP-type and C3HC4-type zinc finger-containing protein 1; EC 2.3.2.31; HBV-associated factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; HOIL-1; Hepatitis B virus X-associated protein 4; RING finger protein 54; RING-type E3 ubiquitin transferase HOIL-1; Ubiquitin-conjugating enzyme 7-interacting protein 3
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAPPGSTLLPNSPAATRGPSLARLCALVDLCLGCSRCTQRLNESTYVLRRVEHDCSREIL
LARFKQATKSKVWRVVGCRPTFPRPLCYQVCHYYSPGLGCRRHRNRCTFARSREEALVWT
FERQHNLQRLWLKAEVQGSGAQGGAGRAADAILTEFGGRFELLCSLCFRRCPPCICRVDP
QGQCPEHGACPSLLAHVSAEGRRKQQFVVVRPRPRAGQPPAYCRFVGRGQPCWRGESRCQ
FAHSAVEMAVWEAEQLGGLQRGDLLTPPAPDGDGRTAPLGQPPGAQLYCPACLVTCHSQE
AFENHCASSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPDLCEYGDACTKAHSAQELQ
EWVRRTQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRVTCNQPLMYQ
AQERKTQYSWTFAVHSEEPLLHVALLKQEPGADFSLVAPGLPPGRLYARGERFRVPSSTA
DFQVGVRVQAASFGTFEQWVVFDFGRRPVLLQKLGLQLGQGRRPGPCRNLALGHPEEMER
WHTGNRHVVPGVERTAEQTALMAKYKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEE
EAAQQQLVAKLTLRGQVFLKTALQTPALNMLFAPPGALYAEVPVPSSLMPDTDQGFLLGR
AVSTALVAPVPAPDNTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQI
DPMTFRLWHQAVDTLPEEQLVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGD
GRRVPPLLIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSG
GHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARE
LRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAE
HTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPP
HPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVV
SHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFT
DARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQ
GVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDIT
ATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDA
ILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHCS
FVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLG
VLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQRVGLE
RLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQ
ATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHIT
DVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTM
EKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFS
RLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLR
WQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQ
DYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATS
PIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQL
KAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRL
LWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEA
SQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCL
EHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSW
EASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGL
NVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVEL
LPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKL
NPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGG
PCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGR
PNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDR
HEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLR
PVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRP
PSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTV
EPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLD
QRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTL
VPAGQVRVCRRPTMPS
Target Type
Literature-reported
Target Bioclass
Enzyme
Family
RBR family
Function
E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. The LUBAC complex is also involved in innate immunity by conjugating linear polyubiquitin chains at the surface of bacteria invading the cytosol to form the ubiquitin coat surrounding bacteria. LUBAC is not able to initiate formation of the bacterial ubiquitin coat, and can only promote formation of linear polyubiquitins on pre-existing ubiquitin. The bacterial ubiquitin coat acts as an 'eat-me' signal for xenophagy and promotes NF-kappa-B activation. Together with OTULIN, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
TTD ID
T71055
Uniprot ID
Q9BYM8
DrugMap ID
TTIKUVC
Ensemble ID
ENST00000353660.7
HGNC ID
HGNC:15864
ChEMBL ID
CHEMBL4296109

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CALU6 SNV: p.M215I DBIA    Probe Info 
COLO678 SNV: p.H469P DBIA    Probe Info 
JURKAT SNV: p.Q198E .
NCIH358 Substitution: p.L149G DBIA    Probe Info 
TE8 Insertion: p.C465AfsTer34 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C411(0.00); C300(0.00); C305(0.00)  LDD0241  [1]
Probe 1
 Probe Info  		Y224(25.70)  LDD3495  [2]
DBIA
 Probe Info  		C300(1.05); C305(1.05); C323(0.97); C332(0.97)  LDD0078  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C323(0.88); C332(0.88)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C30(1.05); C300(0.60); C305(0.60); C323(1.12)  LDD0532  [3]
 LDCM0216  AC100 HCT 116 C30(1.29); C323(0.83); C332(0.83)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C30(1.12); C323(0.88); C332(0.88)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C30(1.15); C323(0.88); C332(0.88)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C30(1.32); C323(1.17); C332(1.17)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C30(1.06); C323(0.87); C332(0.87)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C30(1.27); C323(0.97); C332(0.97)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C30(1.39); C323(1.05); C332(1.05)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C30(1.20); C323(0.82); C332(0.90)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C30(1.29); C323(0.87); C332(0.84)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C30(1.06); C323(0.92); C332(0.87)  LDD0542  [3]
 LDCM0226  AC11 HCT 116 C30(1.20); C300(0.72); C305(0.72); C323(1.10)  LDD0543  [3]
 LDCM0227  AC110 HCT 116 C30(1.31); C323(0.94); C332(0.89)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C30(1.20); C323(0.90); C332(0.85)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C30(1.18); C323(0.96); C332(0.95)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C30(0.92); C305(0.76); C323(0.93); C332(0.93)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C30(0.84); C305(1.07); C323(1.11); C332(1.24)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C30(0.89); C305(1.20); C323(1.23); C332(1.37)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C30(1.05); C305(1.22); C323(1.33); C332(1.34)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C30(0.68); C305(1.10); C323(1.21); C332(1.24)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C30(0.86); C305(1.00); C323(1.01); C332(0.95)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C30(0.88); C305(1.01); C323(0.99); C332(0.99)  LDD0553  [3]
 LDCM0237  AC12 HCT 116 C30(0.94); C300(0.81); C305(0.81); C323(1.10)  LDD0554  [3]
 LDCM0238  AC120 HCT 116 C30(0.80); C305(1.21); C323(1.17); C332(1.10)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C30(1.01); C305(0.95); C323(1.05); C332(1.03)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C30(0.58); C305(1.18); C323(1.10); C332(1.12)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C30(0.55); C305(1.13); C323(1.20); C332(0.95)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C30(0.87); C305(0.97); C323(1.02); C332(0.99)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C30(0.71); C305(1.22); C323(1.27); C332(1.28)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C30(0.74); C305(1.26); C323(1.32); C332(1.20)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C30(0.84); C305(1.23); C323(1.42); C332(1.42)  LDD0562  [3]
 LDCM0246  AC128 HCT 116 C30(1.14); C323(1.09); C332(1.09)  LDD0563  [3]
 LDCM0247  AC129 HCT 116 C30(1.11); C323(0.70); C332(0.70)  LDD0564  [3]
 LDCM0249  AC130 HCT 116 C30(1.18); C323(1.03); C332(1.03)  LDD0566  [3]
 LDCM0250  AC131 HCT 116 C30(1.02); C323(0.84); C332(0.84)  LDD0567  [3]
 LDCM0251  AC132 HCT 116 C30(1.19); C323(0.75); C332(0.75)  LDD0568  [3]
 LDCM0252  AC133 HCT 116 C30(1.11); C323(0.97); C332(0.97)  LDD0569  [3]
 LDCM0253  AC134 HCT 116 C30(1.21); C323(0.90); C332(0.90)  LDD0570  [3]
 LDCM0254  AC135 HCT 116 C30(1.08); C323(0.90); C332(0.90)  LDD0571  [3]
 LDCM0255  AC136 HCT 116 C30(1.20); C323(0.82); C332(0.82)  LDD0572  [3]
 LDCM0256  AC137 HCT 116 C30(1.20); C323(0.75); C332(0.75)  LDD0573  [3]
 LDCM0257  AC138 HCT 116 C30(1.26); C323(0.84); C332(0.84)  LDD0574  [3]
 LDCM0258  AC139 HCT 116 C30(1.26); C323(0.94); C332(0.94)  LDD0575  [3]
 LDCM0259  AC14 HCT 116 C30(1.26); C300(0.64); C305(0.64); C323(1.08)  LDD0576  [3]
 LDCM0260  AC140 HCT 116 C30(1.53); C323(0.86); C332(0.86)  LDD0577  [3]
 LDCM0261  AC141 HCT 116 C30(1.33); C323(0.95); C332(0.95)  LDD0578  [3]
 LDCM0262  AC142 HCT 116 C30(1.19); C323(0.75); C332(0.75)  LDD0579  [3]
 LDCM0263  AC143 HCT 116 C323(0.93); C332(0.93); C30(0.94); C300(1.13)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C305(0.86); C300(0.93); C30(1.14); C323(1.24)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C305(0.82); C300(0.90); C332(0.94); C323(0.95)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C30(0.99); C323(1.02); C332(1.02); C305(1.04)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C305(0.80); C30(1.05); C300(1.05); C332(1.27)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C305(0.90); C30(1.10); C300(1.20); C332(1.56)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C305(0.92); C30(1.02); C300(1.25); C332(1.27)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C300(0.82); C305(0.82); C30(1.12); C323(1.15)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C300(0.97); C305(0.98); C30(1.00); C332(1.09)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C305(0.95); C323(1.08); C332(1.11); C300(1.15)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C305(0.85); C300(0.94); C30(0.99); C323(1.19)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C305(0.96); C30(0.97); C300(1.21); C323(1.71)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C30(0.97); C300(1.13); C305(0.96); C323(1.09)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C30(1.05); C300(1.07); C305(0.91); C323(1.24)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C30(1.01); C300(0.93); C305(0.77); C323(1.34)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C30(0.89); C300(1.09); C305(0.97); C323(0.99)  LDD2161  [3]
 LDCM0276  AC17 HCT 116 C323(0.90); C332(0.90); C30(0.96)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C30(0.86); C323(1.07); C332(1.07)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C30(0.95); C323(1.02); C332(1.02)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C323(0.79); C332(0.79)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C30(0.94); C323(0.97); C332(0.97)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C30(0.79); C323(1.23); C332(1.23)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C30(0.95); C323(1.09); C332(1.09)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C323(0.81); C332(0.81); C30(0.85)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C323(0.95); C332(0.95); C30(1.00)  LDD0601  [3]
 LDCM0285  AC25 HCT 116 C305(0.98); C323(1.02); C332(1.02); C30(1.32)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C323(1.08); C332(1.08); C305(1.15); C30(1.24)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C305(0.98); C323(1.14); C332(1.14); C30(1.23)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C305(1.01); C323(1.05); C332(1.05); C30(1.11)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C30(1.20); C323(1.25); C332(1.25); C305(1.33)  LDD0606  [3]
 LDCM0290  AC3 HCT 116 C323(0.81); C332(0.81)  LDD0607  [3]
 LDCM0291  AC30 HCT 116 C323(1.16); C332(1.16); C30(1.19); C305(1.51)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C323(1.17); C332(1.17); C305(1.21); C30(1.55)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C305(1.17); C323(1.25); C332(1.25); C30(1.43)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C305(0.80); C30(1.23); C323(1.33); C332(1.33)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C305(0.73); C323(1.32); C332(1.32); C30(1.39)  LDD0612  [3]
 LDCM0296  AC35 HCT 116 C30(0.83); C323(0.84); C332(0.84)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C323(0.88); C332(0.88); C30(0.96)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C323(0.96); C332(0.96); C30(1.08)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C30(0.97); C323(0.98); C332(0.98)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C30(0.85); C323(1.08); C332(1.08)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C323(1.04); C332(1.04)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C30(0.92); C323(0.96); C332(0.96)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C323(0.93); C332(0.93); C30(1.19)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C323(0.97); C332(0.97); C30(1.03)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C323(0.95); C332(0.95); C30(1.08)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C323(0.94); C332(0.94); C30(0.98)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C323(1.04); C332(1.04); C30(1.08)  LDD0624  [3]
 LDCM0308  AC46 HCT 116 C323(0.88); C332(0.88); C300(1.02); C305(1.06)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C323(0.96); C332(0.96); C300(0.97); C305(1.03)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C323(0.97); C332(0.97); C300(1.01); C305(1.04)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C300(0.90); C305(1.15); C323(1.43); C332(1.43)  LDD0628  [3]
 LDCM0312  AC5 HCT 116 C323(0.86); C332(0.86)  LDD0629  [3]
 LDCM0313  AC50 HCT 116 C300(0.86); C305(1.16); C323(1.46); C332(1.46)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C323(0.78); C332(0.78); C300(0.80); C305(0.84)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C323(0.88); C332(0.88); C300(0.95); C305(0.99)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C300(0.74); C305(1.01); C323(1.12); C332(1.12)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C300(0.88); C305(1.02); C323(1.30); C332(1.30)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C300(0.80); C305(1.26); C323(1.50); C332(1.50)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C300(0.76); C305(1.28); C323(1.68); C332(1.68)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C323(1.12); C332(1.12); C305(1.37); C460(2.34)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C323(1.17); C332(1.17); C305(1.52); C460(1.93)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C323(1.34); C332(1.34); C305(1.58); C460(1.82)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C300(1.01); C305(1.01); C30(1.04); C323(1.12)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C323(1.20); C332(1.20); C305(1.41); C460(1.59)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C323(1.11); C332(1.11); C460(1.46); C305(1.57)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C323(1.35); C332(1.35); C305(1.94); C460(2.16)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C323(1.20); C332(1.20); C305(1.52); C460(1.58)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C323(1.28); C332(1.28); C305(1.51); C460(1.81)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C305(0.86); C323(1.00); C332(1.00); C460(2.26)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C305(0.90); C323(1.06); C332(1.06); C460(1.63)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C305(1.03); C323(1.16); C332(1.16); C460(1.19)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C323(0.99); C332(0.99)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C323(0.88); C332(0.88)  LDD0650  [3]
 LDCM0334  AC7 HCT 116 C300(0.81); C305(0.81); C323(1.05); C332(1.05)  LDD0651  [3]
 LDCM0335  AC70 HCT 116 C323(0.79); C332(0.79)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C323(0.78); C332(0.78)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C323(0.91); C332(0.91)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C323(1.19); C332(1.19)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C323(0.99); C332(0.99)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C323(1.24); C332(1.24)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C323(1.01); C332(1.01)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C323(1.14); C332(1.14)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C323(0.79); C332(0.79)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C323(0.87); C332(0.87)  LDD0661  [3]
 LDCM0345  AC8 HCT 116 C300(0.63); C305(0.63); C30(1.10); C323(1.14)  LDD0662  [3]
 LDCM0346  AC80 HCT 116 C323(0.97); C332(0.97)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C323(0.80); C332(0.80)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C323(1.07); C332(1.07)  LDD0665  [3]
 LDCM0349  AC83 HCT 116 C30(0.98); C300(1.30); C305(1.30); C323(1.34)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C30(0.99); C300(1.02); C305(1.02); C323(1.13)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C323(0.94); C332(0.94); C30(0.97); C300(1.15)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C30(1.00); C323(1.05); C332(1.05); C300(1.29)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C323(0.82); C332(0.82); C30(0.96); C300(1.12)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C323(1.03); C332(1.03); C30(1.22); C300(1.31)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C30(0.99); C323(1.18); C332(1.18); C300(1.43)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C323(0.82); C332(0.82); C30(0.98); C300(1.18)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C30(0.91); C300(1.22); C305(1.22); C323(1.30)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C30(0.85); C300(1.08); C305(1.08); C323(1.32)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C30(0.98); C323(1.05); C332(1.05); C300(1.07)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C323(0.94); C332(0.94); C300(1.01); C305(1.01)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C323(0.93); C332(0.93); C30(0.96); C300(1.27)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C30(0.85); C300(0.95); C305(0.95); C323(1.01)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C30(0.95); C300(1.14); C305(1.14); C323(1.26)  LDD0681  [3]
 LDCM0365  AC98 HCT 116 C323(1.08); C332(1.08); C30(1.26)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C323(0.71); C332(0.71); C30(1.23)  LDD0683  [3]
 LDCM0248  AKOS034007472 HCT 116 C30(1.03); C300(0.87); C305(0.87); C323(1.05)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C300(0.74); C305(0.74); C323(1.07); C332(1.07)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C300(0.63); C305(0.63); C30(1.03); C323(1.42)  LDD0592  [3]
 LDCM0020  ARS-1620 HCC44 C300(1.05); C305(1.05); C323(0.97); C332(0.97)  LDD0078  [3]
 LDCM0367  CL1 HCT 116 C323(0.90); C332(0.90); C30(1.04); C460(1.08)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C323(0.93); C332(0.93); C30(0.96); C460(0.99)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C323(0.85); C332(0.85)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C300(0.85); C305(0.85); C30(1.16); C323(1.20)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C300(0.74); C305(0.74); C323(1.00); C332(1.00)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C300(0.69); C305(0.69); C323(1.00); C332(1.00)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C300(0.71); C305(0.71); C323(1.01); C332(1.01)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C30(0.91); C323(1.03); C332(1.03)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C30(1.00); C323(1.10); C332(1.10)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C30(1.00); C323(1.17); C332(1.17)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C30(0.96); C323(1.16); C332(1.16)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C30(0.94); C323(1.10); C332(1.10)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C460(0.93); C30(0.97); C323(1.22); C332(1.22)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C30(1.00); C323(1.11); C332(1.11)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C30(0.91); C323(1.00); C332(1.00)  LDD0698  [3]
 LDCM0382  CL112 HCT 116 C323(0.86); C332(0.86); C305(1.08); C30(1.14)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C305(0.98); C323(1.13); C332(1.13); C30(1.20)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C323(0.84); C332(0.84); C305(1.05); C30(1.25)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C305(1.02); C30(1.14); C323(1.15); C332(1.15)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C305(0.82); C323(1.10); C332(1.10); C30(1.19)  LDD0703  [3]
 LDCM0387  CL117 HCT 116 C30(0.97); C323(1.32); C332(1.32)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C30(0.98); C323(1.07); C332(1.07)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C30(0.96); C323(1.20); C332(1.20)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C30(1.07); C460(1.07); C323(1.42); C332(1.42)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C30(0.92); C323(1.00); C332(1.00)  LDD0708  [3]
 LDCM0392  CL121 HCT 116 C305(0.88); C300(0.95); C323(3.16); C332(3.16)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C300(0.87); C323(0.92); C332(0.92); C305(1.01)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C300(0.84); C323(1.03); C332(1.03); C305(1.03)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C300(0.90); C305(1.20); C323(1.24); C332(1.24)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C305(0.85); C323(0.97); C332(0.97); C460(1.58)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C323(0.99); C332(0.99); C305(1.17); C460(1.84)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C460(0.71); C323(0.99); C332(0.99); C305(1.10)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C323(1.31); C332(1.31); C305(1.67); C460(1.71)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C460(0.89); C323(1.13); C332(1.13); C30(1.15)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C30(1.05); C460(1.22); C323(1.26); C332(1.26)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C460(0.93); C323(1.10); C332(1.10); C30(1.17)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C300(0.91); C305(0.98); C323(1.06); C332(1.06)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C323(0.89); C332(0.89); C300(0.96); C305(0.96)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C300(0.89); C305(0.89); C323(0.91); C332(0.91)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C300(1.00); C305(1.00); C460(1.17); C30(1.19)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C460(0.85); C30(0.98); C323(1.06); C332(1.06)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C300(1.03); C305(1.03); C30(1.14); C460(1.19)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C300(0.99); C305(0.99); C460(1.13); C30(1.21)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C460(1.01); C300(1.10); C305(1.10); C30(1.14)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C300(0.93); C305(0.93); C460(1.00); C30(1.14)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C30(1.33); C300(0.91); C305(0.91); C323(1.28)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C30(1.17); C300(0.90); C305(0.90); C323(1.40)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C30(1.26); C300(0.85); C305(0.85); C323(1.18)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C30(1.21); C300(0.90); C305(0.90); C323(1.29)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C30(1.24); C300(0.79); C305(0.79); C323(1.56)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C30(1.41); C300(0.81); C305(0.81); C323(1.22)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C30(1.02); C323(0.99); C332(0.99); C460(0.88)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C30(1.26); C300(0.89); C305(0.89); C323(1.19)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C460(1.07)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C30(1.09); C300(0.88); C305(1.03); C323(1.08)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C30(0.96); C300(1.15); C305(1.11); C323(1.21)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C30(1.17); C300(0.78); C305(0.96); C323(1.25)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C30(1.31); C300(0.81); C305(1.10); C323(0.93)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C30(1.03); C300(0.67); C305(0.91); C323(1.13)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C30(1.27); C300(0.73); C305(1.02); C323(1.10)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C30(1.07); C300(0.98); C305(1.17); C323(1.26)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C30(1.04); C323(1.10); C332(1.10); C460(0.78)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C30(1.04); C300(0.78); C305(0.89); C323(0.86)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C30(1.05); C300(0.82); C305(0.97); C323(1.26)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C30(1.08); C300(0.77); C305(0.81); C323(0.84)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C30(1.13); C300(1.09); C305(1.12); C323(1.09)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C30(1.21); C300(0.70); C305(1.02); C323(1.18)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C30(1.07); C300(0.86); C305(1.11); C323(1.05)  LDD0752  [3]
 LDCM0436  CL46 HCT 116 C30(1.12); C300(0.95); C305(0.95); C323(0.88)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C30(1.01); C300(1.04); C305(1.04); C323(0.85)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C30(0.98); C300(0.85); C305(0.85); C323(0.92)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C30(1.09); C300(1.25); C305(1.25); C323(0.95)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C30(1.01); C323(0.87); C332(0.87); C460(0.95)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C30(1.02); C300(1.06); C305(1.06); C323(0.83)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C30(1.15); C300(0.84); C305(0.84); C323(0.94)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C30(1.05); C300(0.61); C305(0.61); C323(0.98)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C30(0.97); C300(0.92); C305(0.92); C323(0.87)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C30(1.03); C300(1.02); C305(1.02); C323(0.92)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C30(0.96); C300(1.32); C305(1.32); C323(0.87)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C30(0.94); C300(0.99); C305(0.99); C323(0.89)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C30(1.00); C300(1.33); C305(1.33); C323(0.95)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C30(1.07); C300(1.02); C305(1.02); C323(0.89)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C30(1.08); C300(0.97); C305(0.97); C323(0.92)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C30(0.96); C323(1.02); C332(1.02); C460(1.31)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C30(1.13); C300(0.84); C305(0.84); C323(0.83)  LDD0769  [3]
 LDCM0453  CL61 HCT 116 C30(1.38); C323(0.99); C332(0.99); C460(1.07)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C30(1.40); C323(1.03); C332(1.03); C460(1.23)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C30(1.30); C323(1.00); C332(1.00); C460(0.79)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C30(1.32); C323(1.12); C332(1.12); C460(1.07)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C30(1.44); C323(0.97); C332(0.97); C460(1.10)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C30(1.37); C323(1.11); C332(1.11); C460(1.19)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C30(1.29); C323(0.99); C332(0.99); C460(1.19)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C30(1.13); C323(1.06); C332(1.06); C460(0.91)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C30(1.38); C323(0.91); C332(0.91); C460(0.93)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C30(1.02); C323(1.19); C332(1.19); C460(1.20)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C30(1.16); C323(1.05); C332(1.05); C460(1.02)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C30(1.42); C323(1.02); C332(1.02); C460(0.99)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C30(1.36); C323(0.99); C332(0.99); C460(1.04)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C30(1.42); C323(1.20); C332(1.20); C460(1.04)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C30(1.32); C323(1.25); C332(1.25); C460(1.01)  LDD0784  [3]
 LDCM0469  CL76 HCT 116 C30(1.05); C300(1.00); C305(1.00); C323(1.72)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C30(1.15); C300(1.15); C305(1.15); C323(1.02)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C30(1.07); C300(0.87); C305(0.87); C323(1.02)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C30(1.15); C300(1.00); C305(1.00); C323(1.12)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C30(1.11); C323(1.29); C332(1.29); C460(0.81)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C30(1.12); C300(1.03); C305(1.03); C323(1.43)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C30(1.17); C300(0.89); C305(0.89); C323(1.04)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C30(1.15); C300(0.94); C305(0.94); C323(2.30)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C30(0.95); C300(0.95); C305(0.95); C323(1.89)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C30(0.99); C300(1.20); C305(1.20); C323(1.23)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C30(1.06); C300(0.83); C305(0.83); C323(1.04)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C30(1.00); C300(0.82); C305(0.82); C323(1.04)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C30(1.03); C300(0.84); C305(0.84); C323(1.00)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C30(1.05); C300(0.74); C305(0.74); C323(1.61)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C30(1.14); C300(0.95); C305(0.95); C323(1.76)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C30(1.06); C323(0.89); C332(0.89); C460(0.93)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C30(1.03); C300(0.84); C305(0.84); C323(0.84)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C323(1.13); C332(1.13)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C323(0.57); C332(0.57)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C323(0.85); C332(0.85)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C323(0.89); C332(0.89)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C323(0.83); C332(0.83)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C323(0.94); C332(0.94)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C323(0.76); C332(0.76)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C323(0.68); C332(0.68)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C323(1.01); C332(1.01)  LDD0811  [3]
 LDCM0468  Fragment33 HCT 116 C30(1.30); C323(1.14); C332(1.14); C460(0.99)  LDD0785  [3]
 LDCM0427  Fragment51 HCT 116 C30(1.06); C300(0.61); C305(0.85); C323(0.82)  LDD0744  [3]
 LDCM0022  KB02 HCT 116 C282(1.74); C285(1.74); C305(1.35); C300(1.35)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C282(2.56); C285(2.56); C305(1.56); C300(1.56)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C282(1.53); C285(1.53); C305(1.52); C300(1.52)  LDD0082  [3]
 LDCM0021  THZ1 HCT 116 C460(1.15); C493(1.05); C323(1.17); C332(1.17)  LDD2173  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 11 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
N-alpha-acetyltransferase 10 (NAA10) Acetyltransferase family P41227
Glycerate kinase (GLYCTK) Glycerate kinase type-2 family Q8IVS8
Proteasome subunit alpha type-1 (PSMA1) Peptidase T1A family P25786
Testis-specific serine/threonine-protein kinase 3 (TSSK3) CAMK Ser/Thr protein kinase family Q96PN8
E3 ubiquitin-protein ligase RNF31 (RNF31) RBR family Q96EP0
RanBP-type and C3HC4-type zinc finger-containing protein 1 (RBCK1) RBR family Q9BYM8
Ubiquitin-conjugating enzyme E2 K (UBE2K) Ubiquitin-conjugating enzyme family P61086
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) Ubiquitin-conjugating enzyme family P68036
Ubiquitin-conjugating enzyme E2 N (UBE2N) Ubiquitin-conjugating enzyme family P61088
Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) Ubiquitin-conjugating enzyme family O14933
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C8 (HOXC8) Antp homeobox family P31273
Zinc finger protein 414 (ZNF414) Krueppel C2H2-type zinc-finger protein family Q96IQ9
Other
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-1 (ATXN1) ATXN1 family P54253
Synaptonemal complex central element protein 1 (SYCE1) SYCE family Q8N0S2
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
Mitogen-activated protein kinase-binding protein 1 (MAPKBP1) . O60336
NADH dehydrogenase 1 alpha subcomplex assembly factor 3 (NDUFAF3) . Q9BU61
NF-kappa-B essential modulator (IKBKG) . Q9Y6K9
Sharpin (SHARPIN) . Q9H0F6
TAR DNA-binding protein 43 (TARDBP) . Q13148

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060