Details of the Target

General Information of Target

Target ID LDTP17493
Target Name Ubinuclein-2 (UBN2)
Gene Name UBN2
Gene ID 254048
Synonyms
KIAA2030; Ubinuclein-2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQHVSSSQSSQRHVQWPGACPGAGEEQPACSQPSLPLTLPSPSHQLQQLMVRGGPAGGQN
MNVDLQGVGPGLQGSPQVTLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQV
QTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGDFVDASVLVRQISLSPSSGGHFV
FQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGLQ
PLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLLPGAGGAAGF
GMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASPEMAQMRKQCLDY
HHQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKERLYGPLQAYLRQNDLDIEEEEEE
HFEVINDEVKVVARKHGQPGTPVAIATQLPPRTSAAFPAQQQPLQQIHMGTPVPGDVNSI
KMEASKRQ
Target Bioclass
Other
Family
Ubinuclein family
Uniprot ID
Q6ZU65
Ensemble ID
ENST00000473989.8
HGNC ID
HGNC:21931

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
42MGBA SNV: p.K706N .
CAOV3 SNV: p.Q1312R .
CCK81 SNV: p.M84L .
ECC2 SNV: p.L573F DBIA    Probe Info 
HEC1 SNV: p.Q1223H .
LNCaP clone FGC SNV: p.A634V; p.K812N .
LS180 Deletion: p.R33AfsTer153 DBIA    Probe Info 
MEWO SNV: p.G598R DBIA    Probe Info 
MFE319 SNV: p.L616F .
SCC25 SNV: p.A326T .
SKMEL2 Deletion: p.N582MfsTer16
SNV: .		 DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TH211
 Probe Info  		Y558(20.00)  LDD0257  [1]
DBIA
 Probe Info  		C562(1.01); C141(0.94); C152(0.94); C966(0.91)  LDD0078  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [3]
IPM
 Probe Info  		N.A.  LDD0025  [4]
TFBX
 Probe Info  		N.A.  LDD0027  [4]
YN-1
 Probe Info  		N.A.  LDD0447  [5]
Phosphinate-6
 Probe Info  		C966(0.00); C562(0.00)  LDD0018  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C562(0.94)  LDD0812  [2]
 LDCM0215  AC10 HCT 116 C562(0.78)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C562(0.78)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C562(0.66)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C562(0.65)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C562(1.22)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C562(0.88)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C562(0.82)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C562(0.82)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C562(1.02)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C562(0.87)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C562(0.69)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C562(0.88)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C562(0.68)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C562(0.78)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C562(0.89)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C562(0.99)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C562(0.95)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C562(0.90)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C562(0.93)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C562(0.96)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C562(1.19)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C562(1.03)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C562(0.79)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C562(0.84)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C562(1.00)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C562(1.38)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C562(1.16)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C562(1.17)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C562(1.04)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C562(1.01)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C562(1.32)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C562(1.53)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C562(0.76)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C562(1.05)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C562(0.74)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C562(0.77)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C562(0.96)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C562(1.05)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C562(1.23)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C562(1.01)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C562(0.84)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C562(1.07)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C562(1.03)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C562(0.77)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C562(1.47)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C562(1.07)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C562(1.41)  LDD0579  [2]
 LDCM0263  AC143 HEK-293T C562(1.12); C966(1.00)  LDD0861  [2]
 LDCM0264  AC144 HEK-293T C562(0.92); C966(0.79)  LDD0862  [2]
 LDCM0265  AC145 HEK-293T C562(0.98); C966(0.68)  LDD0863  [2]
 LDCM0266  AC146 HEK-293T C562(1.00); C966(0.76)  LDD0864  [2]
 LDCM0267  AC147 HEK-293T C562(0.72); C966(0.67)  LDD0865  [2]
 LDCM0268  AC148 HEK-293T C562(0.96); C966(0.67)  LDD0866  [2]
 LDCM0269  AC149 HEK-293T C562(1.00); C966(0.90)  LDD0867  [2]
 LDCM0270  AC15 HCT 116 C562(0.81)  LDD0587  [2]
 LDCM0271  AC150 HEK-293T C562(1.12); C966(0.69)  LDD0869  [2]
 LDCM0272  AC151 HEK-293T C562(1.06); C966(0.75)  LDD0870  [2]
 LDCM0273  AC152 HEK-293T C562(1.07); C966(1.01)  LDD0871  [2]
 LDCM0274  AC153 HEK-293T C562(1.01); C966(0.84)  LDD0872  [2]
 LDCM0621  AC154 HEK-293T C562(1.16); C966(1.01)  LDD2162  [2]
 LDCM0622  AC155 HEK-293T C562(1.16); C966(0.98)  LDD2163  [2]
 LDCM0623  AC156 HEK-293T C562(1.04); C966(0.61)  LDD2164  [2]
 LDCM0624  AC157 HEK-293T C562(0.89); C966(0.76)  LDD2165  [2]
 LDCM0276  AC17 HCT 116 C623(0.93); C562(1.08)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C623(1.04); C562(1.69)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C562(0.81); C623(1.10)  LDD0595  [2]
 LDCM0279  AC2 HEK-293T C562(0.94)  LDD0877  [2]
 LDCM0280  AC20 HCT 116 C623(0.86); C562(1.01)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C623(0.85); C562(1.03)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C623(0.90); C562(1.09)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C623(1.01); C562(1.20)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C562(0.91); C623(0.91)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C623(1.06)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C623(1.23)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C623(1.14)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C623(1.14)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C623(1.32)  LDD0606  [2]
 LDCM0290  AC3 HEK-293T C562(0.93)  LDD0888  [2]
 LDCM0291  AC30 HCT 116 C623(1.33)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C623(1.11)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C623(1.54)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C623(1.08)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C623(0.99)  LDD0612  [2]
 LDCM0296  AC35 HEK-293T C562(1.04)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C562(1.08)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C562(1.01)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C562(0.96)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C562(1.09)  LDD0898  [2]
 LDCM0301  AC4 HEK-293T C562(1.01)  LDD0899  [2]
 LDCM0302  AC40 HEK-293T C562(0.98)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C562(0.95)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C562(0.93)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C562(1.02)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C562(1.09)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C562(0.94)  LDD0905  [2]
 LDCM0308  AC46 HCT 116 C562(0.97)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C562(0.99)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C562(0.99)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C562(1.57)  LDD0628  [2]
 LDCM0312  AC5 HEK-293T C562(0.86)  LDD0910  [2]
 LDCM0313  AC50 HCT 116 C562(1.13)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C562(0.92)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C562(1.20)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C562(1.12)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C562(1.18)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C562(1.10)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C562(1.67)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C562(1.17)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C562(0.90)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C562(0.76)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C562(0.97)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C562(1.59)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C562(1.24)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C562(0.90)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C562(0.93)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C562(1.05)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C562(0.75)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C562(0.59)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C562(0.84)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C562(0.95)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C562(1.22)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C562(0.74)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C562(1.39)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C562(0.88)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C562(0.98)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C562(1.27)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C562(0.90)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C562(0.77)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C562(1.06)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C562(1.00)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C562(1.10)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C562(1.68)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C562(0.59)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C562(1.04)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C562(0.60)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C562(1.00)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C562(1.13)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C562(1.42)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C562(1.02)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C562(1.14)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C562(1.03)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C562(0.97)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C562(1.36)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C562(1.01)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C562(1.31)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C562(1.26)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C562(1.52)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C562(1.02)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C562(1.66)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C562(1.21)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C562(1.11)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C562(1.49)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C562(0.66)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C562(1.00)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C562(1.25)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C562(1.35)  LDD0592  [2]
 LDCM0020  ARS-1620 HCC44 C562(1.01); C141(0.94); C152(0.94); C966(0.91)  LDD0078  [2]
 LDCM0367  CL1 HEK-293T C562(1.04)  LDD0965  [2]
 LDCM0368  CL10 HEK-293T C562(0.86)  LDD0966  [2]
 LDCM0369  CL100 HEK-293T C562(1.03)  LDD0967  [2]
 LDCM0370  CL101 HCT 116 C562(1.11)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C562(0.77)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C562(0.61)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C562(0.79)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C562(0.95); C623(1.27)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C562(0.99); C623(1.34)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C562(1.11); C623(1.32)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C562(0.88); C623(1.22)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C623(0.97); C562(0.98)  LDD0695  [2]
 LDCM0379  CL11 HEK-293T C562(1.06)  LDD0977  [2]
 LDCM0380  CL110 HCT 116 C562(0.92); C623(1.21)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C623(1.00); C562(1.02)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C623(1.12)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C623(1.18)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C623(1.27)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C623(1.14)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C623(1.00)  LDD0703  [2]
 LDCM0387  CL117 HEK-293T C562(1.05)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C562(1.33)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C562(1.01)  LDD0987  [2]
 LDCM0390  CL12 HEK-293T C562(1.17)  LDD0988  [2]
 LDCM0391  CL120 HEK-293T C562(1.15)  LDD0989  [2]
 LDCM0392  CL121 HCT 116 C562(0.60)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C562(0.87)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C562(0.88)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C562(1.07)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C562(0.66)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C562(1.02)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C562(1.33)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C562(1.02)  LDD0716  [2]
 LDCM0400  CL13 HEK-293T C562(1.02)  LDD0998  [2]
 LDCM0401  CL14 HEK-293T C562(1.26)  LDD0999  [2]
 LDCM0402  CL15 HEK-293T C562(1.24)  LDD1000  [2]
 LDCM0403  CL16 HCT 116 C562(0.86)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C562(0.81)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C562(1.01)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C562(0.88)  LDD0723  [2]
 LDCM0407  CL2 HEK-293T C562(1.25)  LDD1005  [2]
 LDCM0408  CL20 HCT 116 C562(1.00)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C562(0.82)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C562(0.98)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C562(1.27)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C562(0.84)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C562(0.99)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C562(0.78)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C562(0.88)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C562(1.15)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C562(0.64)  LDD0734  [2]
 LDCM0418  CL3 HEK-293T C562(1.01)  LDD1016  [2]
 LDCM0419  CL30 HCT 116 C562(0.92)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C562(1.13); C623(1.01)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C623(1.09)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C623(1.05)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C623(1.15)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C623(0.97)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C623(0.97)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C623(0.95)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C623(1.03)  LDD0745  [2]
 LDCM0429  CL4 HEK-293T C562(1.06)  LDD1027  [2]
 LDCM0430  CL40 HCT 116 C623(0.95)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C623(1.00)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C623(0.96)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C623(0.96)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C623(0.99)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C623(1.09)  LDD0752  [2]
 LDCM0436  CL46 HEK-293T C562(0.77); C966(1.04)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C562(0.99); C966(0.80)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C562(0.96); C966(0.87)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C562(0.81); C966(0.87)  LDD1037  [2]
 LDCM0440  CL5 HEK-293T C562(1.09)  LDD1038  [2]
 LDCM0441  CL50 HEK-293T C562(0.88); C966(0.99)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C562(1.06); C966(1.06)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C562(0.85); C966(1.02)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C562(1.01); C966(1.01)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C562(1.04); C966(1.20)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C562(0.98); C966(0.99)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C562(1.02); C966(1.12)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C562(0.97); C966(1.03)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C562(0.90); C966(1.18)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C562(0.90); C966(1.20)  LDD1048  [2]
 LDCM0451  CL6 HEK-293T C562(1.12)  LDD1049  [2]
 LDCM0452  CL60 HEK-293T C562(0.87); C966(0.97)  LDD1050  [2]
 LDCM0453  CL61 HCT 116 C623(1.05)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C623(0.94)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C623(0.95)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C623(1.04)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C623(0.88)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C623(0.97)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C623(0.88)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C623(0.81)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C623(0.97)  LDD0778  [2]
 LDCM0462  CL7 HEK-293T C562(0.99)  LDD1060  [2]
 LDCM0463  CL70 HCT 116 C623(1.04)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C623(1.01)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C623(1.00)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C623(0.95)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C623(0.87)  LDD0784  [2]
 LDCM0469  CL76 HEK-293T C562(0.91)  LDD1067  [2]
 LDCM0470  CL77 HEK-293T C562(0.94)  LDD1068  [2]
 LDCM0471  CL78 HEK-293T C562(0.68)  LDD1069  [2]
 LDCM0472  CL79 HEK-293T C562(0.72)  LDD1070  [2]
 LDCM0473  CL8 HEK-293T C562(1.19)  LDD1071  [2]
 LDCM0474  CL80 HEK-293T C562(0.85)  LDD1072  [2]
 LDCM0475  CL81 HEK-293T C562(0.79)  LDD1073  [2]
 LDCM0476  CL82 HEK-293T C562(1.04)  LDD1074  [2]
 LDCM0477  CL83 HEK-293T C562(1.17)  LDD1075  [2]
 LDCM0478  CL84 HEK-293T C562(0.76)  LDD1076  [2]
 LDCM0479  CL85 HEK-293T C562(0.81)  LDD1077  [2]
 LDCM0480  CL86 HEK-293T C562(0.68)  LDD1078  [2]
 LDCM0481  CL87 HEK-293T C562(0.79)  LDD1079  [2]
 LDCM0482  CL88 HEK-293T C562(0.94)  LDD1080  [2]
 LDCM0483  CL89 HEK-293T C562(0.85)  LDD1081  [2]
 LDCM0484  CL9 HEK-293T C562(1.34)  LDD1082  [2]
 LDCM0485  CL90 HEK-293T C562(1.02)  LDD1083  [2]
 LDCM0486  CL91 HEK-293T C562(0.87)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C562(1.21)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C562(0.95)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C562(0.89)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C562(0.97)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C562(1.02)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C562(0.92)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C562(0.95)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C562(0.96)  LDD1092  [2]
 LDCM0495  E2913 HEK-293T C515(1.05)  LDD1698  [7]
 LDCM0625  F8 Ramos C966(0.92)  LDD2187  [8]
 LDCM0573  Fragment11 Ramos C966(11.47)  LDD2190  [8]
 LDCM0574  Fragment12 Ramos C966(1.24)  LDD2191  [8]
 LDCM0575  Fragment13 Ramos C966(1.07)  LDD2192  [8]
 LDCM0576  Fragment14 Ramos C966(0.75)  LDD2193  [8]
 LDCM0579  Fragment20 Ramos C966(1.18)  LDD2194  [8]
 LDCM0580  Fragment21 Ramos C966(1.05)  LDD2195  [8]
 LDCM0582  Fragment23 Ramos C966(1.35)  LDD2196  [8]
 LDCM0578  Fragment27 Ramos C966(0.91)  LDD2197  [8]
 LDCM0586  Fragment28 Ramos C966(0.79)  LDD2198  [8]
 LDCM0588  Fragment30 Ramos C966(0.95)  LDD2199  [8]
 LDCM0589  Fragment31 Ramos C966(0.74)  LDD2200  [8]
 LDCM0468  Fragment33 HCT 116 C623(1.11)  LDD0785  [2]
 LDCM0596  Fragment38 Ramos C966(0.69)  LDD2203  [8]
 LDCM0566  Fragment4 Ramos C966(0.76)  LDD2184  [8]
 LDCM0427  Fragment51 HCT 116 C623(1.06)  LDD0744  [2]
 LDCM0610  Fragment52 Ramos C966(1.33)  LDD2204  [8]
 LDCM0614  Fragment56 Ramos C966(1.04)  LDD2205  [8]
 LDCM0569  Fragment7 Ramos C966(1.48)  LDD2186  [8]
 LDCM0022  KB02 HCT 116 C623(1.38); C141(2.88); C152(2.88); C562(1.39)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C623(2.10); C141(1.58); C152(1.58); C562(1.61)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C623(2.11); C141(1.76); C152(1.76); C562(1.27)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C141(1.30); C152(1.30); C562(1.04)  LDD2173  [2]

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
6 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578