Details of the Target

General Information of Target

Target ID LDTP14990
Target Name Tubulin-specific chaperone cofactor E-like protein (TBCEL)
Gene Name TBCEL
Gene ID 219899
Synonyms
LRRC35; Tubulin-specific chaperone cofactor E-like protein; EL; Leucine-rich repeat-containing protein 35
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSDSQDPTTSPVVTTQVELGGCSRQGGGNGFLRFRQHQEVQAFLSLLEDSFVQEFLSKDP
CFQISDKYLLAMVLVYFQRAHLKLSEYTHSSLFLALYLANDMEEDLEGPKCEIFPWALGK
DWCLRVGKFLHQRDKLWARMGFRAVVSRQCCEEVMAKEPFHWAWTRDRRPHHGGVQRVCP
QVPVRLPRGPGLSPPHCSPCGLPQHCSSHLLKPVSSKCPSLTSECHRPPSQNYLSRVKNA
WGGDFLIVLPPQMQLEPGTYSLRIFPKPPARPGH
Target Bioclass
Other
Subcellular location
Cytoplasm, cytoskeleton
Function Acts as a regulator of tubulin stability.
Uniprot ID
Q5QJ74
Ensemble ID
ENST00000422003.6
HGNC ID
HGNC:28115

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C121(1.38); C14(0.91)  LDD0531  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [2]
NAIA_5
 Probe Info  		N.A.  LDD2225  [3]
IPM
 Probe Info  		N.A.  LDD2156  [4]
AOyne
 Probe Info  		15.00  LDD0443  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C121(1.38); C14(0.91)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C14(0.99)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C121(0.60); C14(0.96)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C121(0.91); C14(0.95)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C121(0.72); C14(0.89)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C121(0.55); C14(0.95)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C121(0.37); C14(0.94)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C121(0.60); C14(0.96)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C121(0.41); C14(1.02)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C121(0.45); C14(1.00)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C121(0.59); C14(0.88)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C121(0.40); C14(0.90)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C14(0.96)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C121(0.43); C14(0.88)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C121(0.55); C14(0.92)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C121(0.58); C14(0.96)  LDD0546  [1]
 LDCM0237  AC12 HCT 116 C14(0.86)  LDD0554  [1]
 LDCM0246  AC128 HEK-293T C121(0.61); C14(0.84)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C121(0.60); C14(0.95)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C121(0.57); C14(1.09)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C121(0.59); C14(1.07)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C121(0.78); C14(1.12)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C121(0.60); C14(1.07)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C121(0.78); C14(0.99)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C121(0.71); C14(1.09)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C121(0.88); C14(1.21)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C121(0.92); C14(1.13)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C121(0.76); C14(1.01)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C121(0.77); C14(1.07)  LDD0856  [1]
 LDCM0259  AC14 HCT 116 C14(0.93)  LDD0576  [1]
 LDCM0260  AC140 HEK-293T C121(0.69); C14(1.07)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C121(0.68); C14(0.96)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C121(0.64); C14(0.97)  LDD0860  [1]
 LDCM0263  AC143 HEK-293T C14(0.94)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C14(0.87)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C14(0.92)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C14(0.94)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C14(0.85)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C14(0.89)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C14(1.12)  LDD0867  [1]
 LDCM0270  AC15 HCT 116 C14(0.85)  LDD0587  [1]
 LDCM0271  AC150 HEK-293T C14(0.80)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C14(0.86)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C14(0.95)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C14(0.90)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C14(0.73)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C14(0.97)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C14(0.86)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C14(0.83)  LDD2165  [1]
 LDCM0276  AC17 HCT 116 C121(1.25); C14(1.26)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C14(0.93); C121(1.06)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C14(0.79); C121(1.24)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C14(0.84); C121(1.78)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C14(0.85); C121(1.14)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C14(0.85); C121(1.13)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C14(0.90); C121(1.22)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C14(0.87); C121(1.05)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C14(0.94); C121(1.11)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C121(0.71); C14(1.14)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C14(1.06); C121(1.11)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C121(0.97); C14(1.13)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C121(0.80); C14(1.10)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C121(0.99); C14(1.02)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C14(0.80); C121(1.67)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C121(0.87); C14(1.11)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C121(0.86); C14(1.03)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C121(0.97); C14(1.15)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C121(0.76); C14(1.11)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C121(0.71); C14(1.13)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C121(0.88); C14(1.04)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C121(0.86); C14(1.06)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C121(0.93); C14(1.07)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C14(1.11); C121(1.70)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C121(1.17); C14(1.21)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C14(0.74); C121(1.33)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C14(1.07); C121(1.18)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C121(0.88); C14(1.12)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C14(1.12); C121(1.22)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C14(1.05); C121(1.57)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C121(0.97); C14(1.22)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C121(0.94); C14(1.18)  LDD0624  [1]
 LDCM0308  AC46 HEK-293T C121(0.93); C14(1.19)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C121(1.30); C14(1.55)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C121(1.05); C14(1.23)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C121(1.24); C14(1.56)  LDD0909  [1]
 LDCM0312  AC5 HCT 116 C14(0.70); C121(1.57)  LDD0629  [1]
 LDCM0313  AC50 HEK-293T C121(1.05); C14(1.24)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C121(1.16); C14(1.49)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C121(1.00); C14(1.38)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C121(1.05); C14(1.24)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C121(1.23); C14(1.16)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C121(1.11); C14(1.47)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C121(1.04); C14(1.48)  LDD0917  [1]
 LDCM0320  AC57 HCT 116 C14(0.80)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C14(0.78)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C14(0.86)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C14(1.18)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C14(0.90)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C14(0.92)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C14(0.83)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C14(0.80)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C14(0.95)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C14(0.89)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C14(0.88)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C14(0.93)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C121(0.90)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C121(0.87)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C14(0.91)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C121(1.03)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C121(0.87)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C121(0.92)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C121(1.00)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C121(0.96)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C121(0.94)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C121(0.94)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C121(0.98)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C121(1.02)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C121(0.94)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C14(0.88)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C121(1.05)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C121(0.89)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C121(0.99)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C14(1.15)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C14(1.03)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C14(1.10)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C14(1.50)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C14(0.93)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C14(1.21)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C14(1.31)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C14(0.94)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C14(1.24)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C14(1.42)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C14(0.96)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C14(0.97)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C14(1.20)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C14(1.23)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C14(1.17)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C121(0.83); C14(0.91)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C121(0.66); C14(0.91)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C14(1.15)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C14(1.20)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C14(0.89)  LDD0592  [1]
 LDCM0632  CL-Sc Hep-G2 C14(20.00)  LDD2227  [3]
 LDCM0367  CL1 HCT 116 C14(1.07)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C14(0.92)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C14(0.85); C121(1.23)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C14(0.84)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C14(0.88)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C14(0.86)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C14(0.93)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C121(1.10); C14(1.23)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C121(1.00); C14(1.06)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C121(1.15); C14(1.16)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C121(1.02); C14(1.34)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C14(0.95); C121(1.04)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C14(0.79)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C121(1.14); C14(1.17)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C14(1.01); C121(1.47)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C121(0.77); C14(1.03)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C121(0.85); C14(1.09)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C121(0.95); C14(1.01)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C121(0.89); C14(1.16)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C121(0.79); C14(1.21)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C14(1.17); C121(1.40)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C14(1.09); C121(1.17)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C14(1.13); C121(1.20)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C14(0.85)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C121(1.08); C14(1.18)  LDD0708  [1]
 LDCM0392  CL121 HEK-293T C121(1.03); C14(1.21)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C121(1.04); C14(1.25)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C121(0.94); C14(1.30)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C121(1.10); C14(1.19)  LDD0993  [1]
 LDCM0396  CL125 HCT 116 C14(0.88)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C14(0.91)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C14(0.93)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C14(0.90)  LDD0716  [1]
 LDCM0400  CL13 HCT 116 C14(0.82)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C14(0.87)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C14(0.94)  LDD0719  [1]
 LDCM0403  CL16 HEK-293T C14(1.20); C58(0.98); C62(0.98)  LDD1001  [1]
 LDCM0404  CL17 HCT 116 C14(0.97)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C14(1.04)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C14(0.93)  LDD0723  [1]
 LDCM0407  CL2 HCT 116 C14(1.09)  LDD0724  [1]
 LDCM0408  CL20 HCT 116 C14(1.04)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C14(1.06)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C14(1.08)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C14(0.97)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C14(0.97)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C14(1.02)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C14(0.82)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C14(0.97)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C14(1.01)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C14(0.94)  LDD0734  [1]
 LDCM0418  CL3 HCT 116 C14(0.87)  LDD0735  [1]
 LDCM0419  CL30 HCT 116 C14(0.89)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C14(0.88)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C14(0.87)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C14(1.02)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C14(0.87)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C14(0.94)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C14(0.83)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C14(0.93)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C14(0.88)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C14(0.93)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C14(0.80)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C14(0.79)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C14(0.77)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C14(0.79)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C14(0.98)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C14(0.90)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C121(0.22)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C121(0.69)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C121(0.64)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C121(0.47)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C14(0.91)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C121(0.49)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C121(0.33)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C121(0.79)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C121(0.39)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C121(0.20)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C121(0.34)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C121(0.64)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C121(0.41)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C121(0.45)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C121(0.81)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C14(0.96)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C121(0.46)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C14(1.04)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C14(0.98)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C14(1.05)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C14(1.13)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C14(1.07)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C14(1.13)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C14(1.16)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C14(0.96)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C14(0.93)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C14(0.92)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C14(1.01)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C14(1.12)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C14(1.02)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C14(1.05)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C14(1.03)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C121(0.87); C14(1.34)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C121(0.94); C14(1.12)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C121(0.82); C14(1.37)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C121(0.90); C14(1.22)  LDD0789  [1]
 LDCM0473  CL8 HCT 116 C14(0.97)  LDD0790  [1]
 LDCM0474  CL80 HCT 116 C121(0.98); C14(1.28)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C121(0.88); C14(1.09)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C121(0.92); C14(0.91)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C121(0.85); C14(1.36)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C121(0.94); C14(1.20)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C121(0.91); C14(0.96)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C121(0.99); C14(1.10)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C121(0.95); C14(1.08)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C121(0.88); C14(1.04)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C121(0.77); C14(0.88)  LDD0800  [1]
 LDCM0484  CL9 HCT 116 C14(1.10)  LDD0801  [1]
 LDCM0485  CL90 HCT 116 C121(0.87); C14(1.06)  LDD0802  [1]
 LDCM0486  CL91 HCT 116 C121(1.32); C14(0.92)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C121(1.05); C14(0.80)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C121(1.10); C14(0.70)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C121(0.95); C14(0.76)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C121(1.12); C14(0.80)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C121(1.28); C14(0.78)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C121(1.15); C14(0.77)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C121(1.51); C14(0.89)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C121(1.41); C14(0.82)  LDD0811  [1]
 LDCM0495  E2913 HEK-293T C121(1.07); C14(0.90); C62(1.14)  LDD1698  [6]
 LDCM0468  Fragment33 HCT 116 C14(1.09)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C14(0.91)  LDD0744  [1]
 LDCM0022  KB02 HEK-293T C121(1.02); C14(1.02); C62(0.97)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C121(1.02); C14(1.10); C62(0.92)  LDD1497  [6]
 LDCM0024  KB05 MEL167 C121(1.98)  LDD3316  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein MOX-2 (MEOX2) . P50222
Transcription factor LBX1 (LBX1) . P52954
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Pleckstrin homology domain-containing family F member 2 (PLEKHF2) . Q9H8W4

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840