Details of the Target

General Information of Target

Target ID LDTP00772
Target Name Histone-lysine N-methyltransferase SUV39H1 (SUV39H1)
Gene Name SUV39H1
Gene ID 6839
Synonyms
KMT1A; SUV39H; Histone-lysine N-methyltransferase SUV39H1; EC 2.1.1.355; Histone H3-K9 methyltransferase 1; H3-K9-HMTase 1; Lysine N-methyltransferase 1A; Position-effect variegation 3-9 homolog; Suppressor of variegation 3-9 homolog 1; Su(var)3-9 homolog 1
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
Target Type
Literature-reported
Target Bioclass
Enzyme
Family
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily
Subcellular location
Nucleus
Function
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. Also weakly methylates histone H1 (in vitro). H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation.; (Microbial infection) Plays a role in defense against mycobacterial infections. Methylates M.tuberculosis HupB on 'Lys-140', probably methylates HupB of M.bovis also. Methylation has an inhibitory effect on mycobacterial growth in the host. Macrophages expressing about 60% SUV39H1 are slightly more susceptible to M.bovis or M.tuberculosis infection. Chaetocin (an inhibitor of this enzyme) increases macrophage survival of M.tuberculosis. This protein inhibits biofilm formation by M.tuberculosis via 'Lys-140' trimethylation.
TTD ID
T39519
Uniprot ID
O43463
DrugMap ID
TTUWQTK
Ensemble ID
ENST00000337852.10
HGNC ID
HGNC:11479
ChEMBL ID
CHEMBL1795118

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
EFO27 SNV: p.R285W DBIA    Probe Info 
NCIH1155 SNV: p.S29P DBIA    Probe Info 
RKO SNV: p.Y47H .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C30(1.75)  LDD1702  [1]
DBIA
 Probe Info  		C228(2.43); C232(2.43)  LDD0080  [2]
IA-alkyne
 Probe Info  		C23(0.00); C30(0.00); C246(0.00)  LDD0165  [3]
TFBX
 Probe Info  		N.A.  LDD0148  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C11(0.65); C12(0.65); C402(0.99); C407(1.07)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C228(1.06); C232(1.06); C407(0.71)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C11(0.28); C12(0.28); C228(0.65); C23(0.33)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C11(0.33); C12(0.33); C228(0.53); C23(0.37)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C11(0.31); C12(0.31); C228(0.66); C23(0.42)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C11(0.28); C12(0.28); C228(0.48); C23(0.36)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C11(0.27); C12(0.27); C228(0.50); C23(0.41)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C11(0.27); C12(0.27); C228(0.37); C23(0.33)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C11(0.28); C12(0.28); C228(0.46); C23(0.38)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C11(0.27); C12(0.27); C228(0.52); C23(0.33)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C11(0.42); C12(0.42); C228(0.41); C23(0.43)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C11(0.41); C12(0.41); C228(0.56); C23(0.39)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C228(0.62); C232(0.62); C407(0.92)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C11(0.34); C12(0.34); C228(0.43); C23(0.44)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C11(0.40); C12(0.40); C228(0.39); C23(0.48)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C11(0.34); C12(0.34); C228(0.53); C23(0.41)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C11(1.12); C12(1.12); C228(1.34); C232(1.34)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C11(0.94); C12(1.02); C228(1.29); C232(0.84)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C11(0.80); C12(0.96); C228(0.86); C232(0.91)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C11(0.87); C12(0.87); C228(1.36); C232(1.15)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C11(0.84); C12(0.91); C228(0.99); C232(1.32)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C11(0.83); C12(0.95); C228(1.17); C232(0.99)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C11(0.90); C12(0.81); C228(1.03); C232(0.92)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C228(0.58); C232(0.58); C407(0.73)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C11(0.99); C12(0.84); C228(1.48); C232(0.86)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C11(0.97); C12(1.03); C228(0.87); C232(1.03)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C11(1.07); C12(1.03); C228(0.97); C232(0.86)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C11(0.74); C12(1.06); C228(0.88); C232(1.22)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C11(0.97); C12(0.96); C228(1.13); C232(0.96)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C11(1.05); C12(0.85); C228(1.26); C232(0.89)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C11(0.95); C12(1.05); C228(1.15); C232(0.84)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C11(0.89); C12(0.89); C228(1.06); C232(0.93)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C11(0.97); C12(0.97); C23(0.98); C8(0.97)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C11(1.02); C12(1.02); C23(1.12); C8(1.02)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C11(0.95); C12(0.95); C23(1.13); C8(0.95)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C11(1.07); C12(1.07); C23(1.15); C8(1.07)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C11(0.99); C12(0.99); C23(1.18); C8(0.99)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C11(1.01); C12(1.01); C23(1.24); C8(1.01)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C11(0.88); C12(0.88); C23(1.06); C8(0.88)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C11(1.00); C12(1.00); C23(1.11); C8(1.00)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C11(0.88); C12(0.88); C23(1.13); C8(0.88)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C11(0.96); C12(0.96); C23(1.07); C8(0.96)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C11(0.77); C12(0.77); C23(1.10); C8(0.77)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C11(0.92); C12(0.92); C23(1.07); C8(0.92)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C228(0.85); C232(0.85); C407(0.59)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C11(0.74); C12(0.74); C23(1.14); C8(0.74)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C11(0.74); C12(0.74); C23(1.20); C8(0.74)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C11(1.24); C12(1.24); C23(1.53); C8(1.24)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C402(0.76); C23(1.00); C246(1.08); C407(1.17)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C246(0.50); C23(0.69); C407(0.81); C402(0.83)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C23(0.66); C402(0.72); C246(0.79); C407(0.80)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C23(0.71); C402(0.73); C407(0.90); C246(0.90)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C23(0.51); C246(0.65); C402(0.93); C407(1.11)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C246(0.50); C402(0.79); C23(0.92); C407(0.96)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C246(0.51); C23(0.75); C402(0.78); C407(0.94)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C407(0.67); C228(0.83); C232(0.83)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C23(0.84); C402(0.86); C407(1.08); C246(1.13)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C23(0.61); C246(0.76); C407(0.97); C402(1.11)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C246(0.48); C23(0.65); C402(0.77); C407(0.83)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C246(0.43); C23(0.76); C402(0.77); C407(0.83)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C23(0.61); C246(0.53); C402(0.94); C407(0.92)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C23(0.63); C246(0.56); C402(1.07); C407(1.10)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C23(0.72); C246(1.19); C402(0.87); C407(1.14)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C23(0.79); C246(0.96); C402(0.84); C407(0.80)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C11(0.55); C12(0.55); C8(0.55); C23(0.73)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C11(0.52); C12(0.52); C8(0.52); C228(0.57)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C11(0.59); C12(0.59); C8(0.59); C23(0.65)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C11(0.53); C12(0.53); C8(0.53); C402(1.16)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C11(0.70); C12(0.70); C8(0.70); C23(0.72)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C11(0.63); C12(0.63); C8(0.63); C23(0.73)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C23(0.81); C11(0.90); C12(0.90); C8(0.90)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C11(0.60); C12(0.60); C8(0.60); C23(0.68)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C11(0.77); C12(0.77); C8(0.77); C23(0.79)  LDD0601  [2]
 LDCM0285  AC25 HEK-293T C11(1.23); C12(1.23); C222(1.44); C23(0.78)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C11(1.32); C12(1.32); C222(1.71); C23(0.79)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C11(1.51); C12(1.51); C222(1.73); C23(0.76)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C11(1.80); C12(1.80); C222(1.11); C23(0.65)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C11(1.48); C12(1.48); C222(1.56); C23(0.74)  LDD0887  [2]
 LDCM0290  AC3 HCT 116 C11(0.55); C12(0.55); C8(0.55); C402(1.15)  LDD0607  [2]
 LDCM0291  AC30 HEK-293T C11(1.87); C12(1.87); C222(1.45); C23(0.89)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C11(1.49); C12(1.49); C222(1.18); C23(1.06)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C11(1.54); C12(1.54); C222(1.45); C23(0.86)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C11(1.33); C12(1.33); C222(1.30); C23(0.83)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C11(1.67); C12(1.67); C222(1.58); C23(0.97)  LDD0893  [2]
 LDCM0296  AC35 HCT 116 C228(1.09); C232(1.09)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C228(1.42); C232(1.42)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C228(2.27); C232(2.27)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C228(1.26); C232(1.26)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C228(0.95); C232(0.95)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C11(0.50); C12(0.50); C8(0.50); C402(1.08)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C228(1.52); C232(1.52)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C228(1.20); C232(1.20)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C228(0.96); C232(0.96)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C228(1.08); C232(1.08)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C228(1.34); C232(1.34)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C228(0.95); C232(0.95)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C232(1.17); C228(1.18)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C232(1.05); C228(1.17)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C232(1.70); C228(2.05)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C232(0.70); C228(0.78)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C11(0.53); C12(0.53); C8(0.53); C402(1.11)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C232(0.71); C228(0.86)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C228(3.48); C232(3.69)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C232(1.33); C228(1.37)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C232(0.94); C228(0.99)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C232(0.70); C228(0.75)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C232(0.76); C228(0.81)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C232(0.75); C228(0.77)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C246(0.56); C11(0.58); C12(0.58); C8(0.58)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C11(0.55); C12(0.55); C8(0.55); C246(0.57)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C246(0.43); C11(0.53); C12(0.53); C8(0.53)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C407(0.51); C228(0.99); C232(0.99)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C246(0.57); C11(0.62); C12(0.62); C8(0.62)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C246(0.64); C23(0.84); C11(0.90); C12(0.90)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C246(0.43); C11(0.47); C12(0.47); C8(0.47)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C246(0.61); C11(0.63); C12(0.63); C8(0.63)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C246(0.52); C11(0.59); C12(0.59); C8(0.59)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C11(0.46); C12(0.46); C8(0.46); C246(0.58)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C11(0.45); C12(0.45); C8(0.45); C23(0.73)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C11(0.39); C12(0.39); C8(0.39); C246(0.43)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C11(1.02); C12(1.02); C8(1.02); C23(1.07)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C228(0.96); C11(1.05); C12(1.05); C8(1.05)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C407(0.44); C228(0.94); C232(0.94)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C23(0.96); C228(1.16); C11(1.32); C12(1.32)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C402(1.02); C407(1.02); C11(1.04); C12(1.04)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C11(0.82); C12(0.82); C8(0.82); C228(0.85)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C228(0.83); C11(0.88); C12(0.88); C8(0.88)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C228(0.96); C11(0.99); C12(0.99); C8(0.99)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C228(0.77); C11(0.93); C12(0.93); C8(0.93)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C23(0.87); C11(0.90); C12(0.90); C8(0.90)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C11(0.88); C12(0.88); C8(0.88); C23(0.91)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C23(1.14); C11(1.28); C12(1.28); C8(1.28)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C11(0.84); C12(0.84); C8(0.84); C23(1.03)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C228(0.56); C232(0.56); C407(0.64)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C11(0.80); C12(0.80); C8(0.80); C228(0.85)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C402(0.66); C407(0.66); C228(1.09); C23(1.22)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C228(0.48); C23(1.06); C11(1.17); C12(1.17)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C11(0.43); C12(0.43); C8(0.43); C407(1.58)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C11(0.46); C12(0.46); C8(0.46); C407(1.29)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C11(0.50); C12(0.50); C8(0.50); C407(1.15)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C11(0.41); C12(0.41); C8(0.41); C407(1.51)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C11(0.88); C12(0.88); C8(0.88); C407(1.02)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C11(0.46); C12(0.46); C8(0.46); C407(1.38)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C11(0.41); C12(0.41); C8(0.41); C407(0.86)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C11(0.79); C12(0.79); C8(0.79); C407(1.24)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C11(0.38); C12(0.38); C8(0.38); C407(0.96)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C11(0.39); C12(0.39); C8(0.39); C407(0.95)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C11(0.47); C12(0.47); C8(0.47); C407(1.42)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C11(0.55); C12(0.55); C8(0.55); C407(1.09)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C11(1.06); C12(1.06); C8(1.06); C407(1.16)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C11(0.47); C12(0.47); C8(0.47); C407(0.81)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C11(0.38); C12(0.38); C8(0.38); C407(1.22)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C11(0.28); C12(0.28); C8(0.28); C228(0.33)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C11(0.36); C12(0.36); C8(0.36); C23(0.41)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C228(1.04); C232(1.04); C407(0.71)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C407(0.65); C228(0.90); C232(0.90)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C228(0.56); C232(0.56); C407(0.70)  LDD0592  [2]
 LDCM0367  CL1 HCT 116 C402(0.90); C407(0.90); C23(1.11); C246(1.19)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C246(0.68); C23(0.88); C11(0.97); C12(0.97)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C11(0.48); C12(0.48); C8(0.48); C407(1.03)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C407(0.35); C228(0.73); C232(0.73)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C407(0.40); C228(0.81); C232(0.81)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C407(0.60); C228(0.93); C232(0.93)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C228(0.74); C232(0.74); C407(0.82)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C11(0.50); C12(0.50); C8(0.50); C23(0.59)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C228(0.45); C232(0.51); C11(0.56); C12(0.56)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C11(0.46); C12(0.46); C8(0.46); C23(0.55)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C228(0.40); C232(0.41); C11(0.45); C12(0.45)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C11(0.55); C12(0.55); C8(0.55); C228(0.60)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C246(0.67); C11(0.83); C12(0.83); C8(0.83)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C228(0.48); C11(0.50); C12(0.50); C8(0.50)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C11(0.51); C12(0.51); C8(0.51); C232(0.56)  LDD0698  [2]
 LDCM0382  CL112 HEK-293T C11(1.52); C12(1.52); C222(1.51); C23(0.81)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C11(1.42); C12(1.42); C222(1.50); C23(0.89)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C11(1.32); C12(1.32); C222(2.35); C23(0.74)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C11(1.37); C12(1.37); C222(1.63); C23(0.84)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C11(1.68); C12(1.68); C222(2.09); C23(0.78)  LDD0984  [2]
 LDCM0387  CL117 HCT 116 C228(0.71); C232(0.71)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C228(1.03); C232(1.03)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C228(0.84); C232(0.84)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C246(0.72); C23(0.93); C11(0.94); C12(0.94)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C228(1.28); C232(1.28)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C228(1.58); C232(1.83)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C232(1.09); C228(1.16)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C232(0.74); C228(0.86)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C232(0.88); C228(1.00)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C23(0.72); C11(0.73); C12(0.73); C8(0.73)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C23(0.55); C11(0.60); C12(0.60); C8(0.60)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C11(0.62); C12(0.62); C8(0.62); C246(0.71)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C246(0.42); C11(0.50); C12(0.50); C8(0.50)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C246(0.92); C23(1.02); C11(1.10); C12(1.10)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C246(0.77); C23(0.84); C11(0.90); C12(0.90)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C246(0.73); C402(1.03); C407(1.03); C23(1.08)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C246(0.62); C11(0.81); C12(0.81); C8(0.81)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C407(0.68); C402(0.69); C246(0.71); C23(0.83)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C246(0.71); C407(1.10); C402(1.20); C11(1.38)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C246(0.54); C11(0.81); C12(0.81); C8(0.81)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C402(0.90); C407(0.90); C23(1.08); C246(1.14)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C246(0.53); C11(0.69); C12(0.69); C8(0.69)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C246(0.56); C23(0.75); C407(0.81); C11(0.84)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C246(0.51); C11(0.78); C12(0.78); C8(0.78)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C246(0.52); C23(0.66); C11(0.75); C12(0.75)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C11(0.74); C12(0.74); C23(0.80); C246(0.40)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C11(0.68); C12(0.68); C23(0.76); C246(0.47)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C11(0.69); C12(0.69); C23(0.72); C246(0.54)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C11(0.79); C12(0.79); C23(0.73); C246(0.59)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C11(0.76); C12(0.76); C23(0.69); C246(0.53)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C11(0.78); C12(0.78); C23(0.80); C246(0.56)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C11(0.89); C12(0.89); C23(0.96); C246(0.86)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C11(0.87); C12(0.87); C23(0.89); C246(0.70)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C23(0.58); C232(0.94)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C23(0.80); C232(1.09); C402(0.89); C407(0.89)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C23(0.88); C232(0.87); C402(1.09); C407(1.09)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C23(0.65); C232(0.93); C402(1.26); C407(1.26)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C23(0.78); C232(0.86); C402(1.15); C407(1.15)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C23(0.62); C232(0.68); C402(0.85); C407(0.85)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C23(0.61); C232(0.57); C402(1.01); C407(1.01)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C23(0.55); C232(0.92); C402(1.16); C407(1.16)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C11(0.90); C12(0.90); C23(0.84); C246(0.84)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C23(0.65); C232(0.81); C402(1.10); C407(1.10)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C23(0.81); C232(0.81); C402(1.17); C407(1.17)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C23(0.90); C232(0.70); C402(0.90); C407(0.90)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C23(0.68); C232(1.03); C402(1.61); C407(1.61)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C23(0.71); C232(0.76); C402(1.36); C407(1.36)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C23(0.90); C232(0.77); C402(1.29); C407(1.29)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C402(1.35); C407(1.02)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C402(1.44); C407(1.43)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C402(1.77); C407(1.61)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C402(1.40); C407(1.14)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C11(1.01); C12(1.01); C23(1.20); C246(0.99)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C402(1.68); C407(1.40)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C402(1.46); C407(1.12)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C402(1.40); C407(1.39)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C402(1.23); C407(1.12)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C402(1.04); C407(0.99)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C402(1.17); C407(1.08)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C402(1.36); C407(1.16)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C402(1.48); C407(1.23)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C402(1.17); C407(1.02)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C402(1.28); C407(1.25)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C11(1.19); C12(1.19); C23(1.22); C246(0.77)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C402(1.53); C407(1.33)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C11(0.98); C12(0.98); C228(1.06); C23(0.84)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C11(1.03); C12(1.03); C228(1.20); C23(0.60)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C11(1.24); C12(1.24); C228(1.54); C23(0.58)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C11(0.91); C12(0.91); C228(1.09); C23(0.78)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C11(1.11); C12(1.11); C228(1.09); C23(0.82)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C11(1.57); C12(1.57); C228(1.72); C23(0.58)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C11(1.36); C12(1.36); C228(1.09); C23(0.81)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C11(1.17); C12(1.17); C228(1.80); C23(0.74)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C11(0.98); C12(0.98); C228(1.12); C23(1.02)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C11(0.97); C12(0.97); C23(1.09); C246(0.76)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C11(0.87); C12(0.87); C228(1.53); C23(0.82)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C11(1.31); C12(1.31); C228(1.40); C23(0.74)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C11(1.12); C12(1.12); C228(1.86); C23(0.85)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C11(1.32); C12(1.32); C228(1.21); C23(0.55)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C11(1.30); C12(1.30); C228(1.95); C23(0.79)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C11(0.95); C12(0.95); C228(1.46); C232(1.15)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C11(0.63); C12(0.63); C228(1.02); C232(0.85)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C11(0.68); C12(0.68); C228(1.12); C232(0.93)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C11(0.62); C12(0.62); C228(1.30); C232(1.04)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C11(0.82); C12(0.82); C23(0.90); C246(0.61)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C11(1.29); C12(1.29); C228(1.37); C232(1.25)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C11(0.65); C12(0.65); C228(1.36); C232(1.49)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C11(0.68); C12(0.68); C228(0.74); C232(0.95)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C11(0.60); C12(0.60); C228(0.87); C232(0.94)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C11(0.60); C12(0.60); C228(0.69); C232(0.77)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C11(0.61); C12(0.61); C228(1.47); C232(1.05)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C11(0.65); C12(0.65); C228(1.42); C232(1.17)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C11(0.57); C12(0.57); C228(1.50); C232(1.09)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C11(0.65); C12(0.65); C228(1.07); C232(0.91)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C11(0.75); C12(0.75); C228(0.68); C232(0.62)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C11(0.79); C12(0.79); C23(0.85); C246(0.67)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C11(0.78); C12(0.78); C228(1.02); C232(0.83)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C11(0.57); C12(0.57); C402(0.82); C407(0.90)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C11(0.51); C12(0.51); C402(0.95); C407(0.90)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C11(0.49); C12(0.49); C402(1.15); C407(0.96)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C11(0.51); C12(0.51); C402(1.21); C407(1.15)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C11(0.51); C12(0.51); C402(0.94); C407(0.95)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C11(0.51); C12(0.51); C402(1.22); C407(1.19)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C11(0.49); C12(0.49); C402(1.06); C407(1.14)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C11(0.39); C12(0.39); C402(0.97); C407(0.94)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C11(0.44); C12(0.44); C402(1.07); C407(1.01)  LDD0811  [2]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C30(1.75)  LDD1702  [1]
 LDCM0468  Fragment33 HCT 116 C11(1.40); C12(1.40); C228(1.23); C23(0.97)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C23(0.81); C232(0.43); C402(1.67); C407(1.67)  LDD0744  [2]
 LDCM0022  KB02 HCT 116 C228(2.43); C232(2.43)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C228(3.26); C232(3.26)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C228(1.96); C232(1.96)  LDD0082  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 16 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
26S proteasome regulatory subunit 4 (PSMC1) AAA ATPase family P62191
Histone-lysine N-methyltransferase EZH2 (EZH2) Histone-lysine methyltransferase family Q15910
Histone deacetylase 1 (HDAC1) Histone deacetylase family Q13547
Histone deacetylase 2 (HDAC2) Histone deacetylase family Q92769
Ribosomal RNA-processing protein 8 (RRP8) RRP8 family O43159
Ubiquitin thioesterase ZRANB1 (ZRANB1) Peptidase C64 family Q9UGI0
Kallikrein-6 (KLK6) Peptidase S1 family Q92876
Protein-arginine deiminase type-6 (PADI6) Protein arginine deiminase family Q6TGC4
Dual specificity protein kinase CLK3 (CLK3) CMGC Ser/Thr protein kinase family P49761
TGF-beta receptor type-2 (TGFBR2) TKL Ser/Thr protein kinase family P37173
Arginyl-tRNA--protein transferase 1 (ATE1) R-transferase family O95260
NAD-dependent protein deacetylase sirtuin-1 (SIRT1) Sirtuin family Q96EB6
SPRY domain-containing SOCS box protein 1 (SPSB1) SPSB family Q96BD6
GTP-binding protein 2 (GTPBP2) Classic translation factor GTPase family Q9BX10
E3 ubiquitin-protein ligase TRIM41 (TRIM41) TRIM/RBCC family Q8WV44
DDB1- and CUL4-associated factor 8 (DCAF8) WD repeat DCAF8 family Q5TAQ9
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Oxysterols receptor LXR-alpha (NR1H3) Nuclear hormone receptor family Q13133
Syntaxin-19 (STX19) Syntaxin family Q8N4C7
Transcription factor
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C4 (HOXC4) Antp homeobox family P09017
Homeobox protein Hox-A1 (HOXA1) Antp homeobox family P49639
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Zinc finger protein 436 (ZNF436) Krueppel C2H2-type zinc-finger protein family Q9C0F3
Zinc finger protein 438 (ZNF438) Krueppel C2H2-type zinc-finger protein family Q7Z4V0
Zinc finger protein 649 (ZNF649) Krueppel C2H2-type zinc-finger protein family Q9BS31
Zinc finger protein 670 (ZNF670) Krueppel C2H2-type zinc-finger protein family Q9BS34
Zinc finger protein with KRAB and SCAN domains 5 (ZKSCAN5) Krueppel C2H2-type zinc-finger protein family Q9Y2L8
PHD finger protein 19 (PHF19) Polycomblike family Q5T6S3
B-cell lymphoma/leukemia 11B (BCL11B) . Q9C0K0
Methyl-CpG-binding domain protein 1 (MBD1) . Q9UIS9
Zinc finger and BTB domain-containing protein 2 (ZBTB2) . Q8N680
Other
Click To Hide/Show 23 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
Protein Hook homolog 2 (HOOK2) Hook family Q96ED9
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Leucine zipper putative tumor suppressor 2 (LZTS2) LZTS2 family Q9BRK4
UV excision repair protein RAD23 homolog A (RAD23A) RAD23 family P54725
Serpin H1 (SERPINH1) Serpin family P50454
Splicing factor U2AF 35 kDa subunit (U2AF1) Splicing factor SR family Q01081
Tektin-4 (TEKT4) Tektin family Q8WW24
Cell division cycle-associated protein 4 (CDCA4) . Q9BXL8
Centrosomal protein of 70 kDa (CEP70) . Q8NHQ1
Chromobox protein homolog 1 (CBX1) . P83916
Chromobox protein homolog 3 (CBX3) . Q13185
Chromobox protein homolog 5 (CBX5) . P45973
FYVE, RhoGEF and PH domain-containing protein 5 (FGD5) . Q6ZNL6
G patch domain-containing protein 2-like (GPATCH2L) . Q9NWQ4
Kelch domain-containing protein 4 (KLHDC4) . Q8TBB5
Outer dynein arm-docking complex subunit 3 (ODAD3) . A5D8V7
Protein phosphatase 1 regulatory subunit 16A (PPP1R16A) . Q96I34
Ras association domain-containing protein 1 (RASSF1) . Q9NS23
Ras association domain-containing protein 2 (RASSF2) . P50749
Uncharacterized protein C8orf74 (C8orf74) . Q6P047

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Chaetocin Small molecular drug D04FNI

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255