Details of the Target

General Information of Target

Target ID LDTP00696
Target Name Zinc finger and BTB domain-containing protein 24 (ZBTB24)
Gene Name ZBTB24
Gene ID 9841
Synonyms
KIAA0441; ZNF450; Zinc finger and BTB domain-containing protein 24; Zinc finger protein 450
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAETSPEPSGQLVVHSDAHSDTVLASFEDQRKKGFLCDITLIVENVHFRAHKALLAASSE
YFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKSTEQILATAQFLKVYD
LVKAYTDFQNNHSSPKPTTLNTAGAPVVVISNKKNDPPKRKRGRPKKVNTLQEEKSELAA
EEEIQLRVNNSVQNRQNFVVKGDSGVLNEQIAAKEKEESEPTCEPSREEEMPVEKDENYD
PKTEDGQASQSRYSKRRIWRSVKLKDYKLVGDQEDHGSAKRICGRRKRPGGPEARCKDCG
KVFKYNHFLAIHQRSHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCSKALT
TKHSLLEHMSLHSGQKSFTCDQCGKYFSQNRQLKSHYRVHTGHSLPECKDCHRKFMDVSQ
LKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSDSSAKRRH
CILHTGKKPFSCPECNLQFARLDNLKAHLKIHSKEKHASDASSISGSSNTEEVRNILQLQ
PYQLSTSGEQEIQLLVTDSVHNINFMPGPSQGISIVTAESSQNMTADQAANLTLLTQQPE
QLQNLILSAQQEQTEHIQSLNMIESQMGPSQTEPVHVITLSKETLEHLHAHQEQTEELHL
ATSTSDPAQHLQLTQEPGPPPPTHHVPQPTPLGQEQS
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in BMP2-induced transcription.
Uniprot ID
O43167
Ensemble ID
ENST00000230122.4
HGNC ID
HGNC:21143
ChEMBL ID
CHEMBL5069371

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A431 SNV: p.M369I .
HEC1 SNV: p.S522G DBIA    Probe Info 
HEC1B SNV: p.I623S .
IGR1 SNV: p.S75F .
IM95 Deletion: p.D236MfsTer74 .
KATOIII Deletion: p.T40LfsTer2 .
MFE319 SNV: p.A668T .
MOLT4 SNV: p.S377Y .
OCIAML2 SNV: p.F378S .
ONS76 SNV: p.D156N .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C481(1.30)  LDD0080  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C481(0.62)  LDD1093  [1]
 LDCM0215  AC10 HCT 116 C481(1.16)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C481(0.86)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C481(0.92)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C481(0.92)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C481(1.12)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C481(1.07)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C481(0.94)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C481(1.05)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C481(1.10)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C481(0.74)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C481(0.76)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C481(1.12)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C481(0.74)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C481(0.71)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C481(0.92)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C481(0.89)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C481(1.18)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C481(1.63)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C481(1.53)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C481(1.05)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C481(1.09)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C481(1.06)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C481(0.99)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C481(1.20)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C481(1.02)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C481(1.01)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C481(0.94)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C481(1.02)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C481(1.17)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C481(1.23)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C481(1.38)  LDD0562  [1]
 LDCM0259  AC14 HCT 116 C481(1.13)  LDD0576  [1]
 LDCM0263  AC143 HCT 116 C481(1.07)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C481(1.35)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C481(1.15)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C481(1.32)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C481(1.52)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C481(2.08)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C481(1.46)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C481(1.18)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C481(1.10)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C481(1.12)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C481(1.62)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C481(2.15)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C481(1.35)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C481(1.33)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C481(0.98)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C481(0.84)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C481(0.96)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C481(0.88)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C481(1.00)  LDD0595  [1]
 LDCM0279  AC2 PaTu 8988t C481(0.54)  LDD1158  [1]
 LDCM0280  AC20 HCT 116 C481(1.09)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C481(0.87)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C481(1.00)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C481(0.81)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C481(1.32)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C481(0.99)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C481(1.16)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C481(1.31)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C481(1.12)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C481(1.33)  LDD0606  [1]
 LDCM0290  AC3 PaTu 8988t C481(0.55)  LDD1169  [1]
 LDCM0291  AC30 HCT 116 C481(1.39)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C481(1.28)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C481(1.53)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C481(1.20)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C481(1.20)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C481(0.93)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C481(0.92)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C481(0.77)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C481(1.05)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C481(1.00)  LDD0617  [1]
 LDCM0301  AC4 PaTu 8988t C481(0.54)  LDD1180  [1]
 LDCM0302  AC40 HCT 116 C481(0.93)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C481(0.89)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C481(1.00)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C481(1.31)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C481(0.75)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C481(0.70)  LDD0624  [1]
 LDCM0308  AC46 PaTu 8988t C481(1.17)  LDD1187  [1]
 LDCM0309  AC47 PaTu 8988t C481(1.24)  LDD1188  [1]
 LDCM0310  AC48 PaTu 8988t C481(1.40)  LDD1189  [1]
 LDCM0311  AC49 PaTu 8988t C481(1.18)  LDD1190  [1]
 LDCM0312  AC5 PaTu 8988t C481(0.53)  LDD1191  [1]
 LDCM0313  AC50 PaTu 8988t C481(1.28)  LDD1192  [1]
 LDCM0314  AC51 PaTu 8988t C481(1.10)  LDD1193  [1]
 LDCM0315  AC52 PaTu 8988t C481(1.39)  LDD1194  [1]
 LDCM0316  AC53 PaTu 8988t C481(1.32)  LDD1195  [1]
 LDCM0317  AC54 PaTu 8988t C481(1.69)  LDD1196  [1]
 LDCM0318  AC55 PaTu 8988t C481(1.27)  LDD1197  [1]
 LDCM0319  AC56 PaTu 8988t C481(1.15)  LDD1198  [1]
 LDCM0320  AC57 HCT 116 C481(0.98)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C481(1.00)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C481(0.99)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C481(1.12)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C481(0.98)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C481(0.98)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C481(0.86)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C481(0.79)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C481(0.90)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C481(1.12)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C481(1.20)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C481(0.91)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C481(0.89)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C481(0.88)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C481(0.97)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C481(0.96)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C481(0.80)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C481(1.04)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C481(0.98)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C481(0.84)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C481(0.97)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C481(0.76)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C481(0.92)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C481(0.90)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C481(1.01)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C481(1.09)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C481(0.93)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C481(0.87)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C481(0.86)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C481(1.39)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C481(1.32)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C481(1.22)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C481(1.23)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C481(1.08)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C481(1.09)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C481(1.27)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C481(1.04)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C481(1.29)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C481(1.24)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C481(1.07)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C481(0.99)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C481(1.18)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C481(1.05)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C481(1.35)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C481(1.22)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C481(0.84)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C481(1.10)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C481(1.00)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C481(1.70)  LDD0592  [1]
 LDCM0367  CL1 HEK-293T C481(1.58)  LDD0965  [1]
 LDCM0368  CL10 HEK-293T C481(0.70)  LDD0966  [1]
 LDCM0369  CL100 PaTu 8988t C481(0.48)  LDD1248  [1]
 LDCM0370  CL101 HCT 116 C481(1.22)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C481(0.99)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C481(0.93)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C481(0.97)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C481(0.93)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C481(0.78)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C481(1.10)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C481(0.93)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C481(1.03)  LDD0695  [1]
 LDCM0379  CL11 HEK-293T C481(0.69)  LDD0977  [1]
 LDCM0380  CL110 HCT 116 C481(1.02)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C481(1.04)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C481(0.96)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C481(1.24)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C481(1.25)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C481(1.17)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C481(1.23)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C481(1.04)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C481(1.16)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C481(1.03)  LDD0706  [1]
 LDCM0390  CL12 HEK-293T C481(3.60)  LDD0988  [1]
 LDCM0391  CL120 HCT 116 C481(1.06)  LDD0708  [1]
 LDCM0392  CL121 PaTu 8988t C481(1.19)  LDD1271  [1]
 LDCM0393  CL122 PaTu 8988t C481(1.14)  LDD1272  [1]
 LDCM0394  CL123 PaTu 8988t C481(1.19)  LDD1273  [1]
 LDCM0395  CL124 PaTu 8988t C481(1.27)  LDD1274  [1]
 LDCM0396  CL125 HCT 116 C481(1.05)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C481(0.99)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C481(1.14)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C481(0.95)  LDD0716  [1]
 LDCM0400  CL13 HEK-293T C481(1.91)  LDD0998  [1]
 LDCM0401  CL14 HEK-293T C481(2.54)  LDD0999  [1]
 LDCM0402  CL15 HEK-293T C481(1.50)  LDD1000  [1]
 LDCM0403  CL16 HCT 116 C481(1.01)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C481(0.86)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C481(0.88)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C481(0.94)  LDD0723  [1]
 LDCM0407  CL2 HEK-293T C481(1.46)  LDD1005  [1]
 LDCM0408  CL20 HCT 116 C481(0.87)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C481(0.80)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C481(0.97)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C481(1.04)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C481(0.92)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C481(0.86)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C481(1.05)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C481(1.12)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C481(0.95)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C481(0.92)  LDD0734  [1]
 LDCM0418  CL3 HEK-293T C481(1.42)  LDD1016  [1]
 LDCM0419  CL30 HCT 116 C481(1.01)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C481(0.98)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C481(0.91)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C481(1.04)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C481(1.21)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C481(0.93)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C481(1.10)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C481(0.97)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C481(0.96)  LDD0745  [1]
 LDCM0429  CL4 HEK-293T C481(1.93)  LDD1027  [1]
 LDCM0430  CL40 HCT 116 C481(1.01)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C481(1.02)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C481(0.94)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C481(1.09)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C481(1.05)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C481(1.08)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C481(0.73)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C481(0.73)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C481(0.71)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C481(0.82)  LDD0756  [1]
 LDCM0440  CL5 HEK-293T C481(1.61)  LDD1038  [1]
 LDCM0441  CL50 HCT 116 C481(0.84)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C481(0.97)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C481(0.93)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C481(0.76)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C481(0.74)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C481(0.82)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C481(0.86)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C481(0.79)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C481(0.77)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C481(0.88)  LDD0767  [1]
 LDCM0451  CL6 HEK-293T C481(1.67)  LDD1049  [1]
 LDCM0452  CL60 HCT 116 C481(0.86)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C481(1.12)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C481(1.08)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C481(1.09)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C481(1.27)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C481(1.15)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C481(1.19)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C481(1.15)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C481(1.14)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C481(1.14)  LDD0778  [1]
 LDCM0462  CL7 HEK-293T C481(1.44)  LDD1060  [1]
 LDCM0463  CL70 HCT 116 C481(1.14)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C481(1.11)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C481(1.08)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C481(1.19)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C481(1.17)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C481(0.84)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C481(0.82)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C481(0.83)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C481(0.92)  LDD0789  [1]
 LDCM0473  CL8 HEK-293T C481(1.25)  LDD1071  [1]
 LDCM0474  CL80 HCT 116 C481(0.85)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C481(0.84)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C481(0.77)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C481(0.77)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C481(0.84)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C481(0.77)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C481(0.83)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C481(0.82)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C481(0.84)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C481(0.82)  LDD0800  [1]
 LDCM0484  CL9 HEK-293T C481(0.85)  LDD1082  [1]
 LDCM0485  CL90 HCT 116 C481(0.82)  LDD0802  [1]
 LDCM0486  CL91 PaTu 8988t C481(0.42)  LDD1365  [1]
 LDCM0487  CL92 PaTu 8988t C481(0.41)  LDD1366  [1]
 LDCM0488  CL93 PaTu 8988t C481(0.44)  LDD1367  [1]
 LDCM0489  CL94 PaTu 8988t C481(0.41)  LDD1368  [1]
 LDCM0490  CL95 PaTu 8988t C481(0.48)  LDD1369  [1]
 LDCM0491  CL96 PaTu 8988t C481(0.39)  LDD1370  [1]
 LDCM0492  CL97 PaTu 8988t C481(0.42)  LDD1371  [1]
 LDCM0493  CL98 PaTu 8988t C481(0.46)  LDD1372  [1]
 LDCM0494  CL99 PaTu 8988t C481(0.44)  LDD1373  [1]
 LDCM0495  E2913 HEK-293T C481(0.99); C37(4.31)  LDD1698  [2]
 LDCM0468  Fragment33 HCT 116 C481(1.19)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C481(1.13)  LDD0744  [1]
 LDCM0022  KB02 HCT 116 C481(1.30)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C481(1.11)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C481(1.33)  LDD0082  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytidine deaminase (CDA) Cytidine and deoxycytidylate deaminase family P32320
Ubiquitin thioesterase ZRANB1 (ZRANB1) Peptidase C64 family Q9UGI0
TNF receptor-associated factor 2 (TRAF2) TNF receptor-associated factor family Q12933
E3 ubiquitin-protein ligase TRIM37 (TRIM37) TRIM/RBCC family O94972
E3 ubiquitin-protein ligase TRIM41 (TRIM41) TRIM/RBCC family Q8WV44
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Germ cell-less protein-like 1 (GMCL1) . Q96IK5
Transporter and channel
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Importin subunit alpha-4 (KPNA3) Importin alpha family O00505
MyoD family inhibitor (MDFI) MDFI family Q99750
Alpha-synuclein (SNCA) Synuclein family P37840
Wolframin (WFS1) . O76024
Transcription factor
Click To Hide/Show 17 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transcription regulator protein BACH2 (BACH2) BZIP family Q9BYV9
Endothelial zinc finger protein induced by tumor necrosis factor alpha (ZNF71) Krueppel C2H2-type zinc-finger protein family Q9NQZ8
Zinc finger and BTB domain-containing protein 43 (ZBTB43) Krueppel C2H2-type zinc-finger protein family O43298
Zinc finger protein 526 (ZNF526) Krueppel C2H2-type zinc-finger protein family Q8TF50
Zinc finger protein 639 (ZNF639) Krueppel C2H2-type zinc-finger protein family Q9UID6
Zinc finger protein 79 (ZNF79) Krueppel C2H2-type zinc-finger protein family Q15937
Zinc finger protein 792 (ZNF792) Krueppel C2H2-type zinc-finger protein family Q3KQV3
Zinc finger protein 837 (ZNF837) Krueppel C2H2-type zinc-finger protein family Q96EG3
POU domain, class 6, transcription factor 2 (POU6F2) POU transcription factor family P78424
Krueppel-like factor 15 (KLF15) Sp1 C2H2-type zinc-finger protein family Q9UIH9
TSC22 domain family protein 4 (TSC22D4) TSC-22/Dip/Bun family Q9Y3Q8
Golgin-45 (BLZF1) . Q9H2G9
Homeobox-containing protein 1 (HMBOX1) . Q6NT76
LIM/homeobox protein Lhx8 (LHX8) . Q68G74
Pogo transposable element with ZNF domain (POGZ) . Q7Z3K3
Zinc finger and BTB domain-containing protein 8A (ZBTB8A) . Q96BR9
Zinc finger and BTB domain-containing protein 9 (ZBTB9) . Q96C00
Other
Click To Hide/Show 30 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Afadin- and alpha-actinin-binding protein (SSX2IP) ADIP family Q9Y2D8
Cyclin-D1-binding protein 1 (CCNDBP1) CCNDBP1 family O95273
Testis-specific gene 10 protein (TSGA10) CEP135/TSGA10 family Q9BZW7
Centrosomal protein of 76 kDa (CEP76) CEP76 family Q8TAP6
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
Multicilin (MCIDAS) Geminin family D6RGH6
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
Progranulin (GRN) Granulin family P28799
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Keratin-associated protein 10-5 (KRTAP10-5) KRTAP type 10 family P60370
Keratin-associated protein 10-6 (KRTAP10-6) KRTAP type 10 family P60371
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Keratin-associated protein 10-9 (KRTAP10-9) KRTAP type 10 family P60411
Keratin-associated protein 2-4 (KRTAP2-4) KRTAP type 2 family Q9BYR9
Keratin-associated protein 4-2 (KRTAP4-2) KRTAP type 4 family Q9BYR5
Keratin-associated protein 5-9 (KRTAP5-9) KRTAP type 5 family P26371
Protein LDOC1 (LDOC1) LDOC1 family O95751
Testis-specific Y-encoded-like protein 2 (TSPYL2) Nucleosome assembly protein (NAP) family Q9H2G4
Transmembrane protein 121 (TMEM121) TMEM121 family Q9BTD3
TLE family member 5 (TLE5) WD repeat Groucho/TLE family Q08117
Centrosomal protein of 70 kDa (CEP70) . Q8NHQ1
Leucine-rich repeat-containing protein 18 (LRRC18) . Q8N456
Polyhomeotic-like protein 2 (PHC2) . Q8IXK0
PRKCA-binding protein (PICK1) . Q9NRD5
Protein SPMIP2 (SPMIP2) . Q96LM5
RING finger protein 11 (RNF11) . Q9Y3C5
RNA-binding protein 10 (RBM10) . P98175
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699
TAR DNA-binding protein 43 (TARDBP) . Q13148

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402