Details of the Target

General Information of Target

Target ID LDTP19958
Target Name Pancreatic progenitor cell differentiation and proliferation factor (PPDPF)
Gene Name PPDPF
Gene ID 79144
Synonyms
C20orf149; EXPDF; Pancreatic progenitor cell differentiation and proliferation factor; Exocrine differentiation and proliferation factor
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MEFHYVAQADLELLTSSNPPASASQSTGITGGSHRARPGPVHFIDKVTDKPSHSHPFALK
ENWNLNPEPSSPPSPLFLEAPSRQASQHHGASPGAGTSAGCPFEKCCSTEPCLSGLGDVG
RGEAASLRARPGSGASRGQGPGSRVSCRRDLGKPLHAPAGFSAGEVHTTPLGNLGA
Target Bioclass
Other
Family
PPDPF family
Function Probable regulator of exocrine pancreas development.
Uniprot ID
Q9H3Y8
Ensemble ID
ENST00000370179.8
HGNC ID
HGNC:16142

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A375 SNV: p.S63F .
MIAPACA2 SNV: p.F67L .
TOV21G SNV: p.D15Y .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Curcusone 37
 Probe Info  		4.29  LDD0188  [1]
DBIA
 Probe Info  		C30(1.21); C35(1.21)  LDD0533  [2]
m-APA
 Probe Info  		N.A.  LDD2231  [3]
NAIA_5
 Probe Info  		N.A.  LDD2225  [4]
TFBX
 Probe Info  		C35(0.00); C30(0.00)  LDD0027  [5]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HEK-293T C35(0.78)  LDD0813  [2]
 LDCM0216  AC100 HCT 116 C30(1.21); C35(1.21)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C30(1.39); C35(1.39)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C30(1.38); C35(1.38)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C30(2.03); C35(2.03)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C30(1.25); C35(1.25)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C30(1.67); C35(1.67)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C30(1.37); C35(1.37)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C30(1.35); C35(1.57)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C30(1.10); C35(1.05)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C30(1.04); C35(0.90)  LDD0542  [2]
 LDCM0226  AC11 HEK-293T C35(0.73)  LDD0824  [2]
 LDCM0227  AC110 HCT 116 C30(1.10); C35(1.04)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C30(1.06); C35(0.96)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C30(1.28); C35(1.35)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C30(1.05); C35(1.05)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C30(1.09); C35(1.09)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C30(1.50); C35(1.50)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C30(1.33); C35(1.33)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C30(1.28); C35(1.28)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C30(1.69); C35(1.69)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C30(1.10); C35(1.10)  LDD0553  [2]
 LDCM0237  AC12 HEK-293T C35(0.89)  LDD0835  [2]
 LDCM0238  AC120 HCT 116 C30(1.24); C35(1.24)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C30(1.06); C35(1.06)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C30(1.33); C35(1.33)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C30(0.90); C35(0.90)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C30(1.06); C35(1.06)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C30(1.23); C35(1.23)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C30(1.36); C35(1.36)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C30(1.20); C35(1.20)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C30(1.05); C35(1.05)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C30(0.51); C35(0.51)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C30(1.00); C35(1.00)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C30(0.80); C35(0.80)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C30(0.85); C35(0.85)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C30(0.99); C35(0.99)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C30(1.47); C35(1.47)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C30(1.04); C35(1.04)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C30(0.85); C35(0.85)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C30(1.05); C35(1.05)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C30(1.23); C35(1.23)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C30(1.00); C35(1.00)  LDD0575  [2]
 LDCM0259  AC14 HEK-293T C35(0.83)  LDD0857  [2]
 LDCM0260  AC140 HCT 116 C30(0.91); C35(0.91)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C30(0.93); C35(0.93)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C30(1.01); C35(1.01)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C30(0.81); C35(0.81)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C30(1.32); C35(1.32)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C30(0.90); C35(0.90)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C30(1.16); C35(1.16)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C30(1.27); C35(1.27)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C30(1.44); C35(1.44)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C30(1.20); C35(1.20)  LDD0586  [2]
 LDCM0270  AC15 HEK-293T C35(0.86)  LDD0868  [2]
 LDCM0271  AC150 HCT 116 C30(1.11); C35(1.11)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C30(1.21); C35(1.21)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C30(1.52); C35(1.52)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C30(1.70); C35(1.70)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C30(1.14); C35(1.14)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C30(1.23); C35(1.23)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C30(0.99); C35(0.99)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C30(0.91); C35(0.91)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C30(1.20); C35(1.20)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C30(1.98); C35(1.98)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C30(1.53); C35(1.53)  LDD0595  [2]
 LDCM0280  AC20 HCT 116 C30(0.95); C35(0.95)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C30(1.60); C35(1.60)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C30(1.05); C35(1.05)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C30(1.48); C35(1.48)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C30(1.04); C35(1.04)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C30(1.14); C35(1.14)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C30(1.05); C35(1.05)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C30(1.15); C35(1.15)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C30(1.12); C35(1.12)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C30(1.00); C35(1.00)  LDD0606  [2]
 LDCM0291  AC30 HCT 116 C30(1.18); C35(1.18)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C30(1.34); C35(1.34)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C30(1.22); C35(1.22)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C30(1.26); C35(1.26)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C30(1.48); C35(1.48)  LDD0612  [2]
 LDCM0296  AC35 HEK-293T C35(0.82)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C35(0.74)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C35(0.74)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C35(0.86)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C35(0.82)  LDD0898  [2]
 LDCM0302  AC40 HEK-293T C35(0.95)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C35(0.91)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C35(0.88)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C35(0.93)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C35(0.95)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C35(0.88)  LDD0905  [2]
 LDCM0320  AC57 HCT 116 C30(1.38); C35(1.38)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C30(1.20); C35(1.20)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C30(1.57); C35(1.57)  LDD0639  [2]
 LDCM0323  AC6 HEK-293T C35(0.85)  LDD0921  [2]
 LDCM0324  AC60 HCT 116 C30(1.13); C35(1.13)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C30(1.10); C35(1.10)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C30(1.24); C35(1.24)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C30(1.33); C35(1.33)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C30(1.14); C35(1.14)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C30(0.87); C35(0.87)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C30(0.92); C35(0.92)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C30(0.95); C35(0.95)  LDD0648  [2]
 LDCM0334  AC7 HEK-293T C35(0.88)  LDD0932  [2]
 LDCM0345  AC8 HEK-293T C35(1.04)  LDD0943  [2]
 LDCM0349  AC83 PaTu 8988t C30(1.11); C35(1.11)  LDD1228  [2]
 LDCM0350  AC84 PaTu 8988t C30(1.02); C35(1.02)  LDD1229  [2]
 LDCM0351  AC85 PaTu 8988t C30(0.80); C35(0.80)  LDD1230  [2]
 LDCM0352  AC86 PaTu 8988t C30(0.74); C35(0.74)  LDD1231  [2]
 LDCM0353  AC87 PaTu 8988t C30(0.78); C35(0.78)  LDD1232  [2]
 LDCM0354  AC88 PaTu 8988t C30(0.72); C35(0.72)  LDD1233  [2]
 LDCM0355  AC89 PaTu 8988t C30(0.95); C35(0.95)  LDD1234  [2]
 LDCM0357  AC90 PaTu 8988t C30(0.83); C35(0.83)  LDD1236  [2]
 LDCM0358  AC91 PaTu 8988t C30(0.69); C35(0.69)  LDD1237  [2]
 LDCM0359  AC92 PaTu 8988t C30(0.98); C35(0.98)  LDD1238  [2]
 LDCM0360  AC93 PaTu 8988t C30(0.78); C35(0.78)  LDD1239  [2]
 LDCM0361  AC94 PaTu 8988t C30(0.88); C35(0.88)  LDD1240  [2]
 LDCM0362  AC95 PaTu 8988t C30(0.96); C35(0.96)  LDD1241  [2]
 LDCM0363  AC96 PaTu 8988t C30(0.68); C35(0.68)  LDD1242  [2]
 LDCM0364  AC97 PaTu 8988t C30(0.92); C35(0.92)  LDD1243  [2]
 LDCM0365  AC98 HCT 116 C30(2.20); C35(2.20)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C30(1.17); C35(1.17)  LDD0683  [2]
 LDCM0248  AKOS034007472 HEK-293T C35(0.76)  LDD0846  [2]
 LDCM0356  AKOS034007680 HEK-293T C35(0.94)  LDD0954  [2]
 LDCM0275  AKOS034007705 HEK-293T C35(0.95)  LDD0873  [2]
 LDCM0020  ARS-1620 HCC44 C30(1.32); C35(1.32)  LDD2171  [2]
 LDCM0367  CL1 HCT 116 C30(0.68); C35(0.68)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C30(1.22); C35(1.22)  LDD0685  [2]
 LDCM0370  CL101 HEK-293T C35(0.98)  LDD0968  [2]
 LDCM0371  CL102 HEK-293T C35(0.74)  LDD0969  [2]
 LDCM0372  CL103 HEK-293T C35(0.81)  LDD0970  [2]
 LDCM0373  CL104 HEK-293T C35(0.83)  LDD0971  [2]
 LDCM0374  CL105 HCT 116 C30(1.63); C35(1.63)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C30(1.85); C35(1.85)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C30(1.44); C35(1.44)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C30(2.01); C35(2.01)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C30(1.64); C35(1.64)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C30(1.17); C35(1.17)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C30(1.81); C35(1.81)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C30(1.35); C35(1.35)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C30(1.03); C35(1.03)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C30(1.22); C35(1.22)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C30(1.05); C35(1.05)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C30(1.09); C35(1.09)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C30(1.04); C35(1.04)  LDD0703  [2]
 LDCM0387  CL117 HEK-293T C35(0.79)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C35(0.87)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C35(1.01)  LDD0987  [2]
 LDCM0390  CL12 HCT 116 C30(1.40); C35(1.40)  LDD0707  [2]
 LDCM0391  CL120 HEK-293T C35(0.94)  LDD0989  [2]
 LDCM0396  CL125 HCT 116 C30(0.90); C35(0.90)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C30(0.83); C35(0.83)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C30(1.03); C35(1.03)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C30(1.09); C35(1.09)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C30(1.07); C35(1.07)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C30(0.87); C35(0.87)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C30(1.12); C35(1.12)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C30(2.05); C35(2.05)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C30(1.81); C35(1.81)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C30(3.31); C35(3.31)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C30(1.92); C35(1.92)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C30(0.70); C35(0.70)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C30(1.87); C35(1.87)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C30(4.24); C35(4.24)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C30(4.10); C35(4.10)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C30(1.76); C35(1.76)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C30(3.34); C35(3.34)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C30(2.56); C35(2.56)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C30(2.39); C35(2.39)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C30(1.95); C35(1.95)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C30(2.25); C35(2.25)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C30(2.19); C35(2.19)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C30(0.71); C35(0.71)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C30(1.55); C35(1.55)  LDD0736  [2]
 LDCM0429  CL4 HCT 116 C30(0.70); C35(0.70)  LDD0746  [2]
 LDCM0436  CL46 HCT 116 C30(0.73); C35(0.73)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C30(0.69); C35(0.69)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C30(0.67); C35(0.67)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C30(0.81); C35(0.81)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C30(0.73); C35(0.73)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C30(0.77); C35(0.77)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C30(0.72); C35(0.72)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C30(0.98); C35(0.98)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C30(0.87); C35(0.87)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C30(1.03); C35(1.03)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C30(0.80); C35(0.80)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C30(1.02); C35(1.02)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C30(0.88); C35(0.88)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C30(0.86); C35(0.86)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C30(0.93); C35(0.93)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C30(1.45); C35(1.45)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C30(0.87); C35(0.87)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C30(1.05); C35(1.05)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C30(1.08); C35(1.08)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C30(1.35); C35(1.35)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C30(1.51); C35(1.51)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C30(1.21); C35(1.21)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C30(2.03); C35(2.03)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C30(1.77); C35(1.77)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C30(1.77); C35(1.77)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C30(1.50); C35(1.50)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C30(1.14); C35(1.14)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C30(1.39); C35(1.39)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C30(1.56); C35(1.56)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C30(1.21); C35(1.21)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C30(1.43); C35(1.43)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C30(1.48); C35(1.48)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C30(0.81); C35(0.81)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C30(0.54); C35(0.54)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C30(0.71); C35(0.71)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C30(0.67); C35(0.67)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C30(1.47); C35(1.47)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C30(0.62); C35(0.62)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C30(0.54); C35(0.54)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C30(0.38); C35(0.38)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C30(0.52); C35(0.52)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C30(0.73); C35(0.73)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C30(0.75); C35(0.75)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C30(0.51); C35(0.51)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C30(0.48); C35(0.48)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C30(0.51); C35(0.51)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C30(0.62); C35(0.62)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C30(0.69); C35(0.69)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C30(0.54); C35(0.54)  LDD0802  [2]
 LDCM0033  Curcusone1d MCF-7 4.29  LDD0188  [1]
 LDCM0468  Fragment33 HCT 116 C30(1.55); C35(1.55)  LDD0785  [2]
 LDCM0021  THZ1 HCT 116 C30(1.32); C35(1.32)  LDD2173  [2]

References

1 Total Synthesis and Target Identification of the Curcusone Diterpenes. J Am Chem Soc. 2021 Mar 24;143(11):4379-4386. doi: 10.1021/jacs.1c00557. Epub 2021 Mar 11.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
5 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
6 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004