Details of the Target

General Information of Target

Target ID LDTP18151
Target Name Small ribosomal subunit protein uS3m (MRPS24)
Gene Name MRPS24
Gene ID 64951
Synonyms
Small ribosomal subunit protein uS3m; 28S ribosomal protein S24, mitochondrial; MRP-S24; S24mt; bMRP-47; bMRP47
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQR
LAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTV
SHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQP
LLISADNKPPPRLLSSPHPATHHCPLHPSSLPLTPPSPSLSPSPLHGIFQVIIIQPQVQT
QPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKR
QERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKR
GANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYV
THKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLD
RLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPTVQHPQGHN
Target Bioclass
Other
Family
Universal ribosomal protein uS3 family
Subcellular location
Mitochondrion
Uniprot ID
Q96EL2
Ensemble ID
ENST00000317534.6
HGNC ID
HGNC:14510

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
N1
 Probe Info  		100.00  LDD0242  [1]
STPyne
 Probe Info  		K94(3.42)  LDD2217  [2]
DBIA
 Probe Info  		C103(1.04); C120(1.18)  LDD0531  [3]
ATP probe
 Probe Info  		N.A.  LDD0199  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0161  [6]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [7]
AOyne
 Probe Info  		13.90  LDD0443  [8]
NAIA_5
 Probe Info  		C6(0.00); C120(0.00); C149(0.00)  LDD2223  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C103(1.04); C120(1.18)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C103(0.70)  LDD0532  [3]
 LDCM0216  AC100 PaTu 8988t C120(0.71); C103(0.84)  LDD1095  [3]
 LDCM0217  AC101 PaTu 8988t C120(0.81); C103(0.85)  LDD1096  [3]
 LDCM0218  AC102 PaTu 8988t C120(0.73); C103(0.88)  LDD1097  [3]
 LDCM0219  AC103 PaTu 8988t C120(0.68); C103(0.79)  LDD1098  [3]
 LDCM0220  AC104 PaTu 8988t C120(0.73); C103(0.93)  LDD1099  [3]
 LDCM0221  AC105 PaTu 8988t C120(0.67); C103(1.00)  LDD1100  [3]
 LDCM0222  AC106 PaTu 8988t C120(0.84); C103(0.90)  LDD1101  [3]
 LDCM0223  AC107 PaTu 8988t C120(0.77); C103(0.87)  LDD1102  [3]
 LDCM0224  AC108 PaTu 8988t C120(0.65); C103(0.79)  LDD1103  [3]
 LDCM0225  AC109 PaTu 8988t C120(0.73); C103(0.69)  LDD1104  [3]
 LDCM0226  AC11 HCT 116 C103(0.69)  LDD0543  [3]
 LDCM0227  AC110 PaTu 8988t C120(0.82); C103(0.67)  LDD1106  [3]
 LDCM0228  AC111 PaTu 8988t C120(0.76); C103(0.83)  LDD1107  [3]
 LDCM0229  AC112 PaTu 8988t C120(0.76); C103(0.96)  LDD1108  [3]
 LDCM0237  AC12 HCT 116 C103(0.76)  LDD0554  [3]
 LDCM0259  AC14 HCT 116 C103(0.73)  LDD0576  [3]
 LDCM0263  AC143 HCT 116 C120(1.46)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C120(1.15)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C120(1.10)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C120(1.63)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C120(1.19)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C120(1.45)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C120(1.24)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C103(0.65)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C120(0.97)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C120(0.96)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C120(1.22)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C120(1.37)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C120(1.26)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C120(1.40)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C120(1.19)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C120(0.89)  LDD2161  [3]
 LDCM0276  AC17 HCT 116 C103(0.79)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C103(0.78)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C103(0.65)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C103(1.09); C120(1.13)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C103(0.83)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C103(0.76)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C103(1.00)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C103(0.68)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C103(0.76)  LDD0601  [3]
 LDCM0285  AC25 PaTu 8988t C103(1.28)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C103(0.96)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C103(1.12)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C103(1.05)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C103(1.10)  LDD1168  [3]
 LDCM0290  AC3 HCT 116 C103(1.37); C120(1.52)  LDD0607  [3]
 LDCM0291  AC30 PaTu 8988t C103(1.06)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C103(1.23)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C103(0.95)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C103(0.97)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C103(0.88)  LDD1174  [3]
 LDCM0296  AC35 HEK-293T C120(1.00); C103(1.04)  LDD1535  [10]
 LDCM0297  AC36 HEK-293T C120(0.99); C103(0.99)  LDD1536  [10]
 LDCM0298  AC37 HEK-293T C120(1.02); C103(1.04)  LDD1537  [10]
 LDCM0299  AC38 HEK-293T C120(1.19); C103(1.06)  LDD1538  [10]
 LDCM0300  AC39 HEK-293T C120(1.00); C103(0.97)  LDD1539  [10]
 LDCM0301  AC4 HCT 116 C103(0.99); C120(1.48)  LDD0618  [3]
 LDCM0302  AC40 HEK-293T C120(1.11); C103(0.94)  LDD1541  [10]
 LDCM0303  AC41 HEK-293T C120(1.03); C103(1.01)  LDD1542  [10]
 LDCM0304  AC42 HEK-293T C120(0.95); C103(0.95)  LDD1543  [10]
 LDCM0305  AC43 HEK-293T C120(0.99); C103(0.90)  LDD1544  [10]
 LDCM0306  AC44 HEK-293T C120(1.04); C103(0.94)  LDD1545  [10]
 LDCM0307  AC45 HEK-293T C120(0.94); C103(1.00)  LDD1546  [10]
 LDCM0308  AC46 HCT 116 C103(1.02)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C103(0.82)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C103(1.10)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C103(1.05)  LDD0628  [3]
 LDCM0312  AC5 HCT 116 C103(1.07); C120(1.85)  LDD0629  [3]
 LDCM0313  AC50 HCT 116 C103(0.89)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C103(1.05)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C103(1.01)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C103(0.94)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C103(0.97)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C103(1.03)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C103(0.87)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C103(0.99)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C103(0.85)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C103(0.92)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C103(0.73)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C103(0.80)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C103(0.93)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C103(0.85)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C103(0.84)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C103(0.87)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C103(1.08)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C103(1.14)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C103(0.80)  LDD0648  [3]
 LDCM0334  AC7 HCT 116 C103(0.85)  LDD0651  [3]
 LDCM0345  AC8 HCT 116 C103(0.74)  LDD0662  [3]
 LDCM0365  AC98 PaTu 8988t C120(0.85); C103(0.93)  LDD1244  [3]
 LDCM0366  AC99 PaTu 8988t C120(0.60); C103(0.91)  LDD1245  [3]
 LDCM0248  AKOS034007472 HCT 116 C103(0.94)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C103(0.72)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C103(0.68)  LDD0592  [3]
 LDCM0367  CL1 HCT 116 C120(0.99)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C120(1.12)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C103(1.14); C120(1.17)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C103(0.68)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C103(0.78)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C103(0.87)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C103(0.81)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C103(0.70)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C103(0.57)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C103(0.70)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C103(0.80)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C103(0.68)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C120(0.94)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C103(0.64)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C103(0.71)  LDD0698  [3]
 LDCM0382  CL112 PaTu 8988t C103(1.05)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C103(1.19)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C103(1.06)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C103(1.18)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C103(1.59)  LDD1265  [3]
 LDCM0387  CL117 HEK-293T C120(1.02); C103(0.98)  LDD1591  [10]
 LDCM0388  CL118 HEK-293T C120(0.94); C103(0.96)  LDD1592  [10]
 LDCM0389  CL119 HEK-293T C120(1.03); C103(0.97)  LDD1593  [10]
 LDCM0390  CL12 HCT 116 C120(0.94)  LDD0707  [3]
 LDCM0391  CL120 HEK-293T C120(0.94); C103(1.05)  LDD1595  [10]
 LDCM0392  CL121 HCT 116 C103(0.63)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C103(0.97)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C103(1.03)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C103(1.03)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C103(1.06)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C103(1.26)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C103(0.85)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C103(0.90)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C120(1.16)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C120(1.04)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C120(1.12)  LDD0719  [3]
 LDCM0403  CL16 PaTu 8988t C120(1.04); C103(0.95)  LDD1282  [3]
 LDCM0404  CL17 PaTu 8988t C120(1.15); C103(0.96)  LDD1283  [3]
 LDCM0405  CL18 PaTu 8988t C120(1.00); C103(0.96)  LDD1284  [3]
 LDCM0406  CL19 PaTu 8988t C120(1.08); C103(0.95)  LDD1285  [3]
 LDCM0407  CL2 HCT 116 C120(0.97)  LDD0724  [3]
 LDCM0408  CL20 PaTu 8988t C120(1.06); C103(0.76)  LDD1287  [3]
 LDCM0409  CL21 PaTu 8988t C120(1.14); C103(0.68)  LDD1288  [3]
 LDCM0410  CL22 PaTu 8988t C120(1.01); C103(0.83)  LDD1289  [3]
 LDCM0411  CL23 PaTu 8988t C120(1.13); C103(0.77)  LDD1290  [3]
 LDCM0412  CL24 PaTu 8988t C120(0.99); C103(0.80)  LDD1291  [3]
 LDCM0413  CL25 PaTu 8988t C120(1.04); C103(1.00)  LDD1292  [3]
 LDCM0414  CL26 PaTu 8988t C120(1.06); C103(0.88)  LDD1293  [3]
 LDCM0415  CL27 PaTu 8988t C120(1.09); C103(1.07)  LDD1294  [3]
 LDCM0416  CL28 PaTu 8988t C120(1.14); C103(0.84)  LDD1295  [3]
 LDCM0417  CL29 PaTu 8988t C120(1.14); C103(0.82)  LDD1296  [3]
 LDCM0418  CL3 HCT 116 C120(0.96)  LDD0735  [3]
 LDCM0419  CL30 PaTu 8988t C120(1.08); C103(0.82)  LDD1298  [3]
 LDCM0420  CL31 HCT 116 C120(1.14)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C120(1.00)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C120(0.94)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C120(1.01)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C120(0.88)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C120(1.15)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C120(0.99)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C120(1.16)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C120(1.03)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C120(1.14)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C120(1.22)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C120(1.02)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C120(1.10)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C120(1.10)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C120(1.15)  LDD0752  [3]
 LDCM0436  CL46 PaTu 8988t C120(0.86); C103(0.84)  LDD1315  [3]
 LDCM0437  CL47 PaTu 8988t C120(0.84); C103(0.96)  LDD1316  [3]
 LDCM0438  CL48 PaTu 8988t C120(0.89); C103(0.74)  LDD1317  [3]
 LDCM0439  CL49 PaTu 8988t C120(0.76); C103(0.91)  LDD1318  [3]
 LDCM0440  CL5 HCT 116 C120(1.10)  LDD0757  [3]
 LDCM0441  CL50 PaTu 8988t C120(0.89); C103(0.71)  LDD1320  [3]
 LDCM0442  CL51 PaTu 8988t C120(0.97); C103(0.82)  LDD1321  [3]
 LDCM0443  CL52 PaTu 8988t C120(0.97); C103(0.79)  LDD1322  [3]
 LDCM0444  CL53 PaTu 8988t C120(0.82); C103(0.68)  LDD1323  [3]
 LDCM0445  CL54 PaTu 8988t C120(0.95); C103(1.04)  LDD1324  [3]
 LDCM0446  CL55 PaTu 8988t C120(0.81); C103(0.74)  LDD1325  [3]
 LDCM0447  CL56 PaTu 8988t C120(0.18); C103(0.79)  LDD1326  [3]
 LDCM0448  CL57 PaTu 8988t C120(0.91); C103(0.85)  LDD1327  [3]
 LDCM0449  CL58 PaTu 8988t C120(0.89); C103(0.84)  LDD1328  [3]
 LDCM0450  CL59 PaTu 8988t C120(0.92); C103(0.81)  LDD1329  [3]
 LDCM0451  CL6 HCT 116 C120(1.13)  LDD0768  [3]
 LDCM0452  CL60 PaTu 8988t C120(0.93); C103(0.99)  LDD1331  [3]
 LDCM0453  CL61 PaTu 8988t C103(0.98)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C103(0.87)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C103(0.85)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C103(0.87)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C103(0.87)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C103(0.80)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C103(0.84)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C103(0.73)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C103(0.69)  LDD1340  [3]
 LDCM0462  CL7 HCT 116 C120(1.06)  LDD0779  [3]
 LDCM0463  CL70 PaTu 8988t C103(0.77)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C103(0.87)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C103(1.14)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C103(0.69)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C103(0.82)  LDD1346  [3]
 LDCM0469  CL76 HCT 116 C103(0.83); C120(1.04)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C103(0.87); C120(1.00)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C103(0.78); C120(0.91)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C103(0.76); C120(1.04)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C120(0.89)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C103(0.99); C120(1.24)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C103(0.83); C120(0.84)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C103(0.71); C120(0.87)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C103(0.75); C120(1.04)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C103(0.75); C120(0.91)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C103(0.83); C120(1.02)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C103(0.99); C120(1.05)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C103(0.81); C120(1.02)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C103(0.78); C120(0.97)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C103(0.70); C120(1.13)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C120(1.06)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C103(1.06); C120(0.98)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C103(1.09); C120(0.96)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C103(1.27); C120(1.09)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C103(1.23); C120(1.03)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C103(0.96); C120(1.20)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C103(0.99); C120(1.31)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C103(1.00); C120(1.15)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C103(1.09); C120(1.18)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C103(1.01); C120(1.21)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C103(1.07); C120(1.02)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C120(0.97); C103(1.05)  LDD1698  [10]
 LDCM0625  F8 Ramos C120(0.30)  LDD2187  [11]
 LDCM0572  Fragment10 Ramos C120(0.20)  LDD2189  [11]
 LDCM0573  Fragment11 Ramos C120(0.90)  LDD2190  [11]
 LDCM0574  Fragment12 Ramos C120(0.36)  LDD2191  [11]
 LDCM0575  Fragment13 Ramos C120(0.69)  LDD2192  [11]
 LDCM0576  Fragment14 Ramos C120(0.90)  LDD2193  [11]
 LDCM0579  Fragment20 Ramos C120(0.27)  LDD2194  [11]
 LDCM0580  Fragment21 Ramos C120(1.38)  LDD2195  [11]
 LDCM0578  Fragment27 Ramos C120(1.12)  LDD2197  [11]
 LDCM0586  Fragment28 Ramos C120(1.29)  LDD2198  [11]
 LDCM0588  Fragment30 Ramos C120(0.29)  LDD2199  [11]
 LDCM0590  Fragment32 Ramos C120(0.25)  LDD2201  [11]
 LDCM0468  Fragment33 PaTu 8988t C103(0.73)  LDD1347  [3]
 LDCM0596  Fragment38 Ramos C120(0.79)  LDD2203  [11]
 LDCM0566  Fragment4 Ramos C120(0.58)  LDD2184  [11]
 LDCM0427  Fragment51 HCT 116 C120(0.96)  LDD0744  [3]
 LDCM0610  Fragment52 Ramos C120(0.32)  LDD2204  [11]
 LDCM0614  Fragment56 Ramos C120(0.47)  LDD2205  [11]
 LDCM0569  Fragment7 Ramos C120(0.30)  LDD2186  [11]
 LDCM0571  Fragment9 Ramos C120(0.68)  LDD2188  [11]
 LDCM0022  KB02 HEK-293T C120(0.96); C103(1.14)  LDD1492  [10]
 LDCM0023  KB03 HEK-293T C120(0.93); C103(0.95)  LDD1497  [10]
 LDCM0024  KB05 COLO792 C103(3.68)  LDD3310  [12]

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
2 Global profiling of lysine reactivity and ligandability in the human proteome. Nat Chem. 2017 Dec;9(12):1181-1190. doi: 10.1038/nchem.2826. Epub 2017 Jul 31.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
9 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
12 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840