Details of the Target

General Information of Target

Target ID LDTP16279
Target Name Coiled-coil domain-containing protein 9 (CCDC9)
Gene Name CCDC9
Gene ID 26093
Synonyms
Coiled-coil domain-containing protein 9
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MPKAKGKTRRQKFGYSVNRKRLNRNARRKAAPRIECSHIRHAWDHAKSVRQNLAEMGLAV
DPNRAVPLRKRKVKAMEVDIEERPKELVRKPYVLNDLEAEASLPEKKGNTLSRDLIDYVR
YMVENHGEDYKAMARDEKNYYQDTPKQIRSKINVYKRFYPAEWQDFLDSLQKRKMEVE
Target Bioclass
Other
Function
Probable component of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.
Uniprot ID
Q9Y3X0
Ensemble ID
ENST00000221922.11
HGNC ID
HGNC:24560

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.18  LDD0402  [1]
Acrolein
 Probe Info  		N.A.  LDD0227  [2]
DBIA
 Probe Info  		C233(1.08)  LDD0078  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [4]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [4]
NAIA_5
 Probe Info  		N.A.  LDD2224  [5]
IPM
 Probe Info  		N.A.  LDD0147  [6]
TFBX
 Probe Info  		N.A.  LDD0148  [6]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C233(0.85)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C233(0.89)  LDD0532  [3]
 LDCM0216  AC100 HCT 116 C233(1.09)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C233(1.10)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C233(0.93)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C233(1.25)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C233(0.73)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C233(1.49)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C233(1.69)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C233(1.17)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C233(1.07)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C233(0.78)  LDD0542  [3]
 LDCM0226  AC11 HCT 116 C233(1.21)  LDD0543  [3]
 LDCM0227  AC110 HCT 116 C233(1.26)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C233(1.47)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C233(1.17)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C233(0.99)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C233(1.61)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C233(1.94)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C233(1.79)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C233(1.45)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C233(1.13)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C233(1.52)  LDD0553  [3]
 LDCM0237  AC12 HCT 116 C233(0.94)  LDD0554  [3]
 LDCM0238  AC120 HCT 116 C233(0.90)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C233(1.33)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C233(1.46)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C233(1.15)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C233(1.41)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C233(1.71)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C233(2.57)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C233(2.13)  LDD0562  [3]
 LDCM0246  AC128 HCT 116 C233(0.92)  LDD0563  [3]
 LDCM0247  AC129 HCT 116 C233(0.92)  LDD0564  [3]
 LDCM0249  AC130 HCT 116 C233(0.91)  LDD0566  [3]
 LDCM0250  AC131 HCT 116 C233(1.05)  LDD0567  [3]
 LDCM0251  AC132 HCT 116 C233(0.95)  LDD0568  [3]
 LDCM0252  AC133 HCT 116 C233(1.02)  LDD0569  [3]
 LDCM0253  AC134 HCT 116 C233(1.17)  LDD0570  [3]
 LDCM0254  AC135 HCT 116 C233(0.95)  LDD0571  [3]
 LDCM0255  AC136 HCT 116 C233(1.21)  LDD0572  [3]
 LDCM0256  AC137 HCT 116 C233(0.97)  LDD0573  [3]
 LDCM0257  AC138 HCT 116 C233(1.08)  LDD0574  [3]
 LDCM0258  AC139 HCT 116 C233(1.09)  LDD0575  [3]
 LDCM0259  AC14 HCT 116 C233(1.10)  LDD0576  [3]
 LDCM0260  AC140 HCT 116 C233(1.17)  LDD0577  [3]
 LDCM0261  AC141 HCT 116 C233(1.25)  LDD0578  [3]
 LDCM0262  AC142 HCT 116 C233(0.88)  LDD0579  [3]
 LDCM0263  AC143 HCT 116 C233(1.21)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C233(1.62)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C233(1.30)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C233(1.33)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C233(1.53)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C233(2.10)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C233(1.85)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C233(0.80)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C233(1.15)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C233(1.26)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C233(1.66)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C233(4.50)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C233(1.99)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C233(1.96)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C233(1.48)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C233(1.45)  LDD2161  [3]
 LDCM0276  AC17 HCT 116 C233(1.14)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C233(1.18)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C233(1.27)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C233(1.06)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C233(1.66)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C233(0.87)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C233(0.95)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C233(0.92)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C233(1.00)  LDD0601  [3]
 LDCM0285  AC25 HEK-293T C233(1.08)  LDD1524  [8]
 LDCM0286  AC26 HEK-293T C233(1.03)  LDD1525  [8]
 LDCM0287  AC27 HEK-293T C233(1.10)  LDD1526  [8]
 LDCM0288  AC28 HEK-293T C233(1.08)  LDD1527  [8]
 LDCM0289  AC29 HEK-293T C233(1.08)  LDD1528  [8]
 LDCM0290  AC3 HCT 116 C233(1.00)  LDD0607  [3]
 LDCM0291  AC30 HEK-293T C233(0.96)  LDD1530  [8]
 LDCM0292  AC31 HEK-293T C233(1.07)  LDD1531  [8]
 LDCM0293  AC32 HEK-293T C233(0.97)  LDD1532  [8]
 LDCM0294  AC33 HEK-293T C233(1.04)  LDD1533  [8]
 LDCM0295  AC34 HEK-293T C233(1.03)  LDD1534  [8]
 LDCM0296  AC35 HEK-293T C233(1.05)  LDD1535  [8]
 LDCM0297  AC36 HEK-293T C233(1.06)  LDD1536  [8]
 LDCM0298  AC37 HEK-293T C233(1.02)  LDD1537  [8]
 LDCM0299  AC38 HEK-293T C233(1.01)  LDD1538  [8]
 LDCM0300  AC39 HEK-293T C233(1.08)  LDD1539  [8]
 LDCM0301  AC4 HCT 116 C233(0.86)  LDD0618  [3]
 LDCM0302  AC40 HEK-293T C233(0.93)  LDD1541  [8]
 LDCM0303  AC41 HEK-293T C233(1.10)  LDD1542  [8]
 LDCM0304  AC42 HEK-293T C233(1.13)  LDD1543  [8]
 LDCM0305  AC43 HEK-293T C233(1.10)  LDD1544  [8]
 LDCM0306  AC44 HEK-293T C233(1.10)  LDD1545  [8]
 LDCM0307  AC45 HEK-293T C233(1.03)  LDD1546  [8]
 LDCM0308  AC46 HEK-293T C233(1.10)  LDD1547  [8]
 LDCM0309  AC47 HEK-293T C233(1.11)  LDD1548  [8]
 LDCM0310  AC48 HEK-293T C233(0.96)  LDD1549  [8]
 LDCM0311  AC49 HEK-293T C233(1.15)  LDD1550  [8]
 LDCM0312  AC5 HCT 116 C233(0.80)  LDD0629  [3]
 LDCM0313  AC50 HEK-293T C233(1.03)  LDD1552  [8]
 LDCM0314  AC51 HEK-293T C233(1.06)  LDD1553  [8]
 LDCM0315  AC52 HEK-293T C233(1.06)  LDD1554  [8]
 LDCM0316  AC53 HEK-293T C233(1.01)  LDD1555  [8]
 LDCM0317  AC54 HEK-293T C233(1.11)  LDD1556  [8]
 LDCM0318  AC55 HEK-293T C233(1.09)  LDD1557  [8]
 LDCM0319  AC56 HEK-293T C233(1.06)  LDD1558  [8]
 LDCM0320  AC57 HCT 116 C233(2.51)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C233(1.79)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C233(1.76)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C233(1.28)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C233(1.57)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C233(1.70)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C233(1.87)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C233(2.34)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C233(2.37)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C233(0.28)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C233(0.25)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C233(0.38)  LDD0648  [3]
 LDCM0334  AC7 HCT 116 C233(0.87)  LDD0651  [3]
 LDCM0345  AC8 HCT 116 C233(1.35)  LDD0662  [3]
 LDCM0349  AC83 HCT 116 C233(3.12)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C233(1.81)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C233(1.00)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C233(1.24)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C233(1.49)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C233(1.58)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C233(2.01)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C233(2.12)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C233(3.38)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C233(2.74)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C233(1.22)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C233(0.76)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C233(1.58)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C233(2.21)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C233(3.90)  LDD0681  [3]
 LDCM0365  AC98 HCT 116 C233(1.28)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C233(1.08)  LDD0683  [3]
 LDCM0248  AKOS034007472 HCT 116 C233(1.15)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C233(1.13)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C233(0.91)  LDD0592  [3]
 LDCM0156  Aniline NCI-H1299 13.78  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C233(1.08)  LDD0078  [3]
 LDCM0632  CL-Sc Hep-G2 C233(20.00); C233(1.48)  LDD2227  [5]
 LDCM0367  CL1 HEK-293T C233(0.91)  LDD1571  [8]
 LDCM0368  CL10 HEK-293T C233(1.14)  LDD1572  [8]
 LDCM0369  CL100 HCT 116 C233(1.02)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C233(0.86)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C233(1.16)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C233(0.94)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C233(0.87)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C233(0.91)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C233(1.03)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C233(1.08)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C233(1.02)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C233(1.17)  LDD0695  [3]
 LDCM0379  CL11 HEK-293T C233(1.06)  LDD1583  [8]
 LDCM0380  CL110 HCT 116 C233(0.89)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C233(0.84)  LDD0698  [3]
 LDCM0382  CL112 HEK-293T C233(1.19)  LDD1586  [8]
 LDCM0383  CL113 HEK-293T C233(0.99)  LDD1587  [8]
 LDCM0384  CL114 HEK-293T C233(1.00)  LDD1588  [8]
 LDCM0385  CL115 HEK-293T C233(1.00)  LDD1589  [8]
 LDCM0386  CL116 HEK-293T C233(1.08)  LDD1590  [8]
 LDCM0387  CL117 HEK-293T C233(1.08)  LDD1591  [8]
 LDCM0388  CL118 HEK-293T C233(1.12)  LDD1592  [8]
 LDCM0389  CL119 HEK-293T C233(1.05)  LDD1593  [8]
 LDCM0390  CL12 HEK-293T C233(0.80)  LDD1594  [8]
 LDCM0391  CL120 HEK-293T C233(1.07)  LDD1595  [8]
 LDCM0392  CL121 HEK-293T C233(1.15)  LDD1596  [8]
 LDCM0393  CL122 HEK-293T C233(1.04)  LDD1597  [8]
 LDCM0394  CL123 HEK-293T C233(0.99)  LDD1598  [8]
 LDCM0395  CL124 HEK-293T C233(1.16)  LDD1599  [8]
 LDCM0396  CL125 HCT 116 C233(0.92)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C233(0.90)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C233(0.95)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C233(1.64)  LDD0716  [3]
 LDCM0400  CL13 HEK-293T C233(1.15)  LDD1604  [8]
 LDCM0401  CL14 HEK-293T C233(0.97)  LDD1605  [8]
 LDCM0402  CL15 HEK-293T C233(0.99)  LDD1606  [8]
 LDCM0403  CL16 HCT 116 C233(1.18)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C233(0.99)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C233(1.05)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C233(1.08)  LDD0723  [3]
 LDCM0407  CL2 HEK-293T C233(0.89)  LDD1611  [8]
 LDCM0408  CL20 HCT 116 C233(1.03)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C233(0.92)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C233(0.71)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C233(1.18)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C233(1.10)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C233(1.18)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C233(1.34)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C233(1.12)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C233(1.63)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C233(1.44)  LDD0734  [3]
 LDCM0418  CL3 HEK-293T C233(0.91)  LDD1622  [8]
 LDCM0419  CL30 HCT 116 C233(1.17)  LDD0736  [3]
 LDCM0420  CL31 HEK-293T C233(1.18)  LDD1624  [8]
 LDCM0421  CL32 HCT 116 C233(1.04)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C233(1.06)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C233(0.96)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C233(0.89)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C233(0.71)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C233(0.85)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C233(1.20)  LDD0745  [3]
 LDCM0429  CL4 HEK-293T C233(0.90)  LDD1633  [8]
 LDCM0430  CL40 HCT 116 C233(0.84)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C233(0.92)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C233(0.41)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C233(0.81)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C233(0.77)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C233(0.82)  LDD0752  [3]
 LDCM0436  CL46 HEK-293T C233(1.06)  LDD1640  [8]
 LDCM0437  CL47 HEK-293T C233(1.12)  LDD1641  [8]
 LDCM0438  CL48 HEK-293T C233(0.99)  LDD1642  [8]
 LDCM0439  CL49 HEK-293T C233(1.01)  LDD1643  [8]
 LDCM0440  CL5 HEK-293T C233(1.02)  LDD1644  [8]
 LDCM0441  CL50 HEK-293T C233(1.00)  LDD1645  [8]
 LDCM0443  CL52 HEK-293T C233(1.07)  LDD1646  [8]
 LDCM0444  CL53 HEK-293T C233(1.05)  LDD1647  [8]
 LDCM0445  CL54 HEK-293T C233(1.07)  LDD1648  [8]
 LDCM0446  CL55 HEK-293T C233(1.08)  LDD1649  [8]
 LDCM0447  CL56 HEK-293T C233(1.03)  LDD1650  [8]
 LDCM0448  CL57 HEK-293T C233(1.10)  LDD1651  [8]
 LDCM0449  CL58 HEK-293T C233(1.12)  LDD1652  [8]
 LDCM0450  CL59 HEK-293T C233(1.25)  LDD1653  [8]
 LDCM0451  CL6 HEK-293T C233(0.92)  LDD1654  [8]
 LDCM0452  CL60 HEK-293T C233(0.97)  LDD1655  [8]
 LDCM0453  CL61 HCT 116 C233(1.29)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C233(1.27)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C233(0.87)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C233(0.59)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C233(0.83)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C233(0.91)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C233(1.23)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C233(1.28)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C233(1.92)  LDD0778  [3]
 LDCM0462  CL7 HEK-293T C233(1.03)  LDD1665  [8]
 LDCM0463  CL70 HCT 116 C233(0.97)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C233(1.05)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C233(1.30)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C233(1.15)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C233(1.28)  LDD0784  [3]
 LDCM0469  CL76 HEK-293T C233(1.05)  LDD1672  [8]
 LDCM0470  CL77 HEK-293T C233(1.12)  LDD1673  [8]
 LDCM0471  CL78 HEK-293T C233(1.05)  LDD1674  [8]
 LDCM0472  CL79 HEK-293T C233(1.05)  LDD1675  [8]
 LDCM0473  CL8 HEK-293T C233(0.90)  LDD1676  [8]
 LDCM0474  CL80 HEK-293T C233(1.02)  LDD1677  [8]
 LDCM0475  CL81 HEK-293T C233(1.14)  LDD1678  [8]
 LDCM0476  CL82 HEK-293T C233(1.06)  LDD1679  [8]
 LDCM0477  CL83 HEK-293T C233(1.12)  LDD1680  [8]
 LDCM0478  CL84 HEK-293T C233(0.93)  LDD1681  [8]
 LDCM0479  CL85 HEK-293T C233(0.97)  LDD1682  [8]
 LDCM0480  CL86 HEK-293T C233(0.92)  LDD1683  [8]
 LDCM0481  CL87 HEK-293T C233(0.95)  LDD1684  [8]
 LDCM0482  CL88 HEK-293T C233(0.96)  LDD1685  [8]
 LDCM0483  CL89 HEK-293T C233(0.99)  LDD1686  [8]
 LDCM0484  CL9 HEK-293T C233(0.95)  LDD1687  [8]
 LDCM0485  CL90 HEK-293T C233(1.03)  LDD1688  [8]
 LDCM0486  CL91 HCT 116 C233(0.89)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C233(1.10)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C233(0.75)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C233(1.15)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C233(0.84)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C233(0.90)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C233(0.85)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C233(0.94)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C233(0.96)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C233(1.12)  LDD1698  [8]
 LDCM0625  F8 Ramos C233(1.14)  LDD2187  [9]
 LDCM0572  Fragment10 Ramos C233(0.37)  LDD2189  [9]
 LDCM0573  Fragment11 Ramos C233(1.11)  LDD2190  [9]
 LDCM0576  Fragment14 Ramos C233(0.74)  LDD2193  [9]
 LDCM0580  Fragment21 Ramos C233(0.21)  LDD2195  [9]
 LDCM0582  Fragment23 Ramos C233(0.60)  LDD2196  [9]
 LDCM0578  Fragment27 Ramos C233(1.13)  LDD2197  [9]
 LDCM0586  Fragment28 Ramos C233(1.35)  LDD2198  [9]
 LDCM0589  Fragment31 Ramos C233(3.75)  LDD2200  [9]
 LDCM0468  Fragment33 HCT 116 C233(1.13)  LDD0785  [3]
 LDCM0596  Fragment38 Ramos C233(1.55)  LDD2203  [9]
 LDCM0566  Fragment4 Ramos C233(0.56)  LDD2184  [9]
 LDCM0427  Fragment51 HCT 116 C233(0.86)  LDD0744  [3]
 LDCM0614  Fragment56 Ramos C233(0.55)  LDD2205  [9]
 LDCM0569  Fragment7 Ramos C233(1.32)  LDD2186  [9]
 LDCM0571  Fragment9 Ramos C233(0.29)  LDD2188  [9]
 LDCM0022  KB02 HCT 116 C233(1.96)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C233(1.20)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C233(1.40)  LDD0082  [3]
 LDCM0109  NEM HeLa N.A.  LDD0227  [2]
 LDCM0021  THZ1 HCT 116 C233(1.15)  LDD2173  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Wolframin (WFS1) . O76024
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
TERF1-interacting nuclear factor 2 (TINF2) . Q9BSI4

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
9 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578