General Information of Target

Target ID LDTP15619
Target Name Zinc finger protein 384 (ZNF384)
Gene Name ZNF384
Gene ID 171017
Synonyms
CAGH1; CIZ; NMP4; TNRC1; Zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repeat-containing gene 1 protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEGAAAREARGTETPRASAPPPAPSEPPAAPRARPRLVFRTQLAHGSPTGKIEGFTNVRE
LYAKIAEAFGIAPTEILFCTLNSHKVDMQKLLGGQIGLEDFIFAHVRGETKEVEVTKTED
ALGLTITDNGAGYAFIKRIKEGSIINRIEAVCVGDSIEAINDHSIVGCRHYEVAKMLREL
PKSQPFTLRLVQPKRAFDMIGQRSRSSKCPVEAKVTSGRETLRLRSGGAATVEEAPSEFE
EEASRKVDDLLESYMGIRDPELASTMVETSKKTASAQEFARCLDSVLGEFAFPDEFVVEV
WAAIGEAREACG
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.
Uniprot ID
Q8TF68
Ensemble ID
ENST00000319770.7
HGNC ID
HGNC:11955

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info 
14.49  LDD0402  [1]
TH211
 Probe Info 
Y270(5.07)  LDD0260  [2]
AHL-Pu-1
 Probe Info 
C42(4.78)  LDD0172  [3]
Acrolein
 Probe Info 
N.A.  LDD0227  [4]
DBIA
 Probe Info 
C42(1.65)  LDD0080  [5]
IA-alkyne
 Probe Info 
C42(0.00); C233(0.00)  LDD0165  [6]
Lodoacetamide azide
 Probe Info 
N.A.  LDD0037  [7]
NAIA_4
 Probe Info 
N.A.  LDD2226  [8]
NAIA_5
 Probe Info 
N.A.  LDD2225  [8]
Compound 10
 Probe Info 
N.A.  LDD2216  [9]
Compound 11
 Probe Info 
N.A.  LDD2213  [9]
IPM
 Probe Info 
N.A.  LDD2156  [10]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C42(4.78)  LDD0172  [3]
 LDCM0214  AC1 HCT 116 C375(1.21); C380(1.21)  LDD0531  [5]
 LDCM0215  AC10 PaTu 8988t C375(1.30); C380(1.30)  LDD1094  [5]
 LDCM0216  AC100 HCT 116 C233(0.94)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C233(0.94)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C233(1.04)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C233(1.13)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C233(1.25)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C233(1.06)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C233(0.99)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C233(2.45)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C233(0.97)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C233(0.90)  LDD0542  [5]
 LDCM0226  AC11 PaTu 8988t C375(1.28); C380(1.28)  LDD1105  [5]
 LDCM0227  AC110 HCT 116 C233(0.90)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C233(1.11)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C233(1.65)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C233(0.95)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C233(1.19)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C233(1.06)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C233(1.02)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C233(0.95)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C233(0.93)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C233(0.97)  LDD0553  [5]
 LDCM0237  AC12 PaTu 8988t C375(1.30); C380(1.30)  LDD1116  [5]
 LDCM0238  AC120 HCT 116 C233(0.98)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C233(0.91)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C233(0.97)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C233(1.20)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C233(1.12)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C233(1.08)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C233(1.56)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C233(1.40)  LDD0562  [5]
 LDCM0246  AC128 PaTu 8988t C375(1.02); C380(1.02)  LDD1125  [5]
 LDCM0247  AC129 PaTu 8988t C375(0.98); C380(0.98)  LDD1126  [5]
 LDCM0249  AC130 PaTu 8988t C375(0.93); C380(0.93)  LDD1128  [5]
 LDCM0250  AC131 PaTu 8988t C375(0.88); C380(0.88)  LDD1129  [5]
 LDCM0251  AC132 PaTu 8988t C375(0.97); C380(0.97)  LDD1130  [5]
 LDCM0252  AC133 PaTu 8988t C375(0.97); C380(0.97)  LDD1131  [5]
 LDCM0253  AC134 PaTu 8988t C375(0.90); C380(0.90)  LDD1132  [5]
 LDCM0254  AC135 PaTu 8988t C375(1.04); C380(1.04)  LDD1133  [5]
 LDCM0255  AC136 PaTu 8988t C375(1.20); C380(1.20)  LDD1134  [5]
 LDCM0256  AC137 PaTu 8988t C375(0.95); C380(0.95)  LDD1135  [5]
 LDCM0257  AC138 PaTu 8988t C375(0.97); C380(0.97)  LDD1136  [5]
 LDCM0258  AC139 PaTu 8988t C375(1.04); C380(1.04)  LDD1137  [5]
 LDCM0259  AC14 PaTu 8988t C375(1.15); C380(1.15)  LDD1138  [5]
 LDCM0260  AC140 PaTu 8988t C375(1.07); C380(1.07)  LDD1139  [5]
 LDCM0261  AC141 PaTu 8988t C375(0.83); C380(0.83)  LDD1140  [5]
 LDCM0262  AC142 PaTu 8988t C375(0.78); C380(0.78)  LDD1141  [5]
 LDCM0263  AC143 HCT 116 C233(0.97); C375(1.05); C380(1.05)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C375(1.07); C380(1.07); C233(1.44)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C375(1.18); C380(1.18); C233(1.24)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C233(1.22); C375(1.30); C380(1.30)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C375(1.23); C380(1.23); C233(1.44)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C375(1.29); C380(1.29); C233(1.69)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C375(1.33); C380(1.33); C233(1.40)  LDD0586  [5]
 LDCM0270  AC15 PaTu 8988t C375(1.22); C380(1.22)  LDD1149  [5]
 LDCM0271  AC150 HCT 116 C375(1.07); C380(1.07); C233(1.13)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C233(1.10); C375(1.25); C380(1.25)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C375(1.20); C380(1.20); C233(1.42)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C375(1.14); C380(1.14); C233(1.73)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C233(1.47); C375(1.18); C380(1.18)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C233(1.39); C375(1.32); C380(1.32)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C233(1.10); C375(1.14); C380(1.14)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C233(1.37); C375(1.05); C380(1.05)  LDD2161  [5]
 LDCM0276  AC17 HEK-293T C375(1.46)  LDD0874  [5]
 LDCM0277  AC18 HEK-293T C375(1.50)  LDD0875  [5]
 LDCM0278  AC19 HEK-293T C375(1.19)  LDD0876  [5]
 LDCM0279  AC2 HCT 116 C375(1.12); C380(1.12)  LDD0596  [5]
 LDCM0280  AC20 HEK-293T C375(1.75)  LDD0878  [5]
 LDCM0281  AC21 HEK-293T C375(2.06)  LDD0879  [5]
 LDCM0282  AC22 HEK-293T C375(1.91)  LDD0880  [5]
 LDCM0283  AC23 HEK-293T C375(1.68)  LDD0881  [5]
 LDCM0284  AC24 HEK-293T C375(1.35)  LDD0882  [5]
 LDCM0285  AC25 HCT 116 C375(1.03); C380(1.03)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C375(0.98); C380(0.98)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C375(1.09); C380(1.09)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C375(1.08); C380(1.08)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C375(1.04); C380(1.04)  LDD0606  [5]
 LDCM0290  AC3 HCT 116 C375(1.12); C380(1.12)  LDD0607  [5]
 LDCM0291  AC30 HCT 116 C375(1.03); C380(1.03)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C375(1.00); C380(1.00)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C375(1.04); C380(1.04)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C375(1.05); C380(1.05)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C375(0.96); C380(0.96)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C375(1.18); C380(1.18)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C375(1.06); C380(1.06)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C375(1.10); C380(1.10)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C375(1.01); C380(1.01)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C375(1.05); C380(1.05)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C375(1.13); C380(1.13)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C375(1.16); C380(1.16)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C375(1.14); C380(1.14)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C375(0.98); C380(0.98)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C375(0.98); C380(0.98)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C375(1.07); C380(1.07)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C375(1.16); C380(1.16)  LDD0624  [5]
 LDCM0308  AC46 HEK-293T C375(1.10)  LDD0906  [5]
 LDCM0309  AC47 HEK-293T C375(1.30)  LDD0907  [5]
 LDCM0310  AC48 HEK-293T C375(1.08)  LDD0908  [5]
 LDCM0311  AC49 HEK-293T C375(1.10)  LDD0909  [5]
 LDCM0312  AC5 HCT 116 C375(1.05); C380(1.05)  LDD0629  [5]
 LDCM0313  AC50 HEK-293T C375(1.01)  LDD0911  [5]
 LDCM0314  AC51 HEK-293T C375(1.26)  LDD0912  [5]
 LDCM0315  AC52 HEK-293T C375(1.16)  LDD0913  [5]
 LDCM0316  AC53 HEK-293T C375(1.14)  LDD0914  [5]
 LDCM0317  AC54 HEK-293T C375(1.27)  LDD0915  [5]
 LDCM0318  AC55 HEK-293T C375(1.18)  LDD0916  [5]
 LDCM0319  AC56 HEK-293T C375(1.04)  LDD0917  [5]
 LDCM0320  AC57 HCT 116 C375(1.19); C380(1.19)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C375(1.20); C380(1.20)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C375(1.26); C380(1.26)  LDD0639  [5]
 LDCM0323  AC6 PaTu 8988t C375(1.40); C380(1.40)  LDD1202  [5]
 LDCM0324  AC60 HCT 116 C375(1.27); C380(1.27)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C375(1.19); C380(1.19)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C375(1.02); C380(1.02)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C375(1.20); C380(1.20)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C375(1.18); C380(1.18)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C375(1.05); C380(1.05)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C375(0.97); C380(0.97)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C375(0.85); C380(0.85)  LDD0648  [5]
 LDCM0332  AC68 HCT 116 C375(1.14); C380(1.14)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C375(1.17); C380(1.17)  LDD0650  [5]
 LDCM0334  AC7 PaTu 8988t C375(1.00); C380(1.00)  LDD1213  [5]
 LDCM0335  AC70 HCT 116 C375(1.20); C380(1.20)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C375(1.03); C380(1.03)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C375(1.01); C380(1.01)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C375(1.06); C380(1.06)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C375(1.10); C380(1.10)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C375(0.97); C380(0.97)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C375(1.09); C380(1.09)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C375(1.22); C380(1.22)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C375(1.01); C380(1.01)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C375(0.93); C380(0.93)  LDD0661  [5]
 LDCM0345  AC8 PaTu 8988t C375(1.16); C380(1.16)  LDD1224  [5]
 LDCM0346  AC80 HCT 116 C375(0.90); C380(0.90)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C375(0.99); C380(0.99)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C375(0.72); C380(0.72)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C233(0.49); C375(1.16); C380(1.16)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C233(0.49); C375(1.21); C380(1.21)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C233(0.48); C375(1.13); C380(1.13)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C233(0.48); C375(1.05); C380(1.05)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C233(0.49); C375(1.15); C380(1.15)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C233(0.48); C375(1.05); C380(1.05)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C233(0.53); C375(1.11); C380(1.11)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C233(0.51); C375(0.93); C380(0.93)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C233(0.44); C375(1.33); C380(1.33)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C233(0.46); C375(1.33); C380(1.33)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C233(0.56); C375(0.99); C380(0.99)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C233(0.36); C375(0.99); C380(0.99)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C233(0.57); C375(1.38); C380(1.38)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C233(0.42); C375(1.36); C380(1.36)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C233(0.50); C375(0.99); C380(0.99)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C233(1.07)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C233(0.89)  LDD0683  [5]
 LDCM0248  AKOS034007472 PaTu 8988t C375(1.30); C380(1.30)  LDD1127  [5]
 LDCM0356  AKOS034007680 PaTu 8988t C375(1.48); C380(1.48)  LDD1235  [5]
 LDCM0275  AKOS034007705 PaTu 8988t C375(1.18); C380(1.18)  LDD1154  [5]
 LDCM0156  Aniline NCI-H1299 11.83  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C375(1.73); C380(1.73)  LDD2171  [5]
 LDCM0367  CL1 HCT 116 C375(0.88); C380(0.88)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C375(0.91); C380(0.91)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C375(0.98); C380(0.98)  LDD0686  [5]
 LDCM0370  CL101 PaTu 8988t C375(1.12); C380(1.12)  LDD1249  [5]
 LDCM0371  CL102 PaTu 8988t C375(1.16); C380(1.16)  LDD1250  [5]
 LDCM0372  CL103 PaTu 8988t C375(1.25); C380(1.25)  LDD1251  [5]
 LDCM0373  CL104 PaTu 8988t C375(1.08); C380(1.08)  LDD1252  [5]
 LDCM0374  CL105 HEK-293T C375(0.97)  LDD0972  [5]
 LDCM0375  CL106 HEK-293T C375(0.92)  LDD0973  [5]
 LDCM0376  CL107 HEK-293T C375(0.95)  LDD0974  [5]
 LDCM0377  CL108 HEK-293T C375(1.28)  LDD0975  [5]
 LDCM0378  CL109 HEK-293T C375(1.10)  LDD0976  [5]
 LDCM0379  CL11 HCT 116 C375(1.18); C380(1.18)  LDD0696  [5]
 LDCM0380  CL110 HEK-293T C375(0.92)  LDD0978  [5]
 LDCM0381  CL111 HEK-293T C375(0.82)  LDD0979  [5]
 LDCM0382  CL112 HCT 116 C375(0.85); C380(0.85)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C375(1.03); C380(1.03)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C375(0.89); C380(0.89)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C375(1.02); C380(1.02)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C375(0.91); C380(0.91)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C375(1.12); C380(1.12)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C375(1.05); C380(1.05)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C375(1.17); C380(1.17)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C375(1.06); C380(1.06)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C375(0.98); C380(0.98)  LDD0708  [5]
 LDCM0392  CL121 HEK-293T C375(1.33)  LDD0990  [5]
 LDCM0393  CL122 HEK-293T C375(1.10)  LDD0991  [5]
 LDCM0394  CL123 HEK-293T C375(1.04)  LDD0992  [5]
 LDCM0395  CL124 HEK-293T C375(1.10)  LDD0993  [5]
 LDCM0396  CL125 HCT 116 C375(1.00); C380(1.00)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C375(1.09); C380(1.09)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C375(0.89); C380(0.89)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C375(1.22); C380(1.22)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C375(1.23); C380(1.23)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C375(1.12); C380(1.12)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C375(1.30); C380(1.30)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C375(1.42); C380(1.42)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C375(1.31); C380(1.31)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C375(2.05); C380(2.05)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C375(1.36); C380(1.36)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C375(1.00); C380(1.00)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C375(1.34); C380(1.34)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C375(1.56); C380(1.56)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C375(1.62); C380(1.62)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C375(1.60); C380(1.60)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C375(1.78); C380(1.78)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C375(1.56); C380(1.56)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C375(1.28); C380(1.28)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C375(1.75); C380(1.75)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C375(1.48); C380(1.48)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C375(1.42); C380(1.42)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C375(1.05); C380(1.05)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C375(1.36); C380(1.36)  LDD0736  [5]
 LDCM0420  CL31 HEK-293T C375(1.21)  LDD1018  [5]
 LDCM0421  CL32 HEK-293T C375(1.00)  LDD1019  [5]
 LDCM0422  CL33 HEK-293T C375(1.35)  LDD1020  [5]
 LDCM0423  CL34 HEK-293T C375(1.68)  LDD1021  [5]
 LDCM0424  CL35 HEK-293T C375(1.21)  LDD1022  [5]
 LDCM0425  CL36 HEK-293T C375(1.27)  LDD1023  [5]
 LDCM0426  CL37 HEK-293T C375(1.59)  LDD1024  [5]
 LDCM0428  CL39 HEK-293T C375(2.35)  LDD1026  [5]
 LDCM0429  CL4 HCT 116 C375(1.27); C380(1.27)  LDD0746  [5]
 LDCM0430  CL40 HEK-293T C375(1.47)  LDD1028  [5]
 LDCM0431  CL41 HEK-293T C375(1.83)  LDD1029  [5]
 LDCM0432  CL42 HEK-293T C375(2.11)  LDD1030  [5]
 LDCM0433  CL43 HEK-293T C375(2.29)  LDD1031  [5]
 LDCM0434  CL44 HEK-293T C375(1.63)  LDD1032  [5]
 LDCM0435  CL45 HEK-293T C375(1.65)  LDD1033  [5]
 LDCM0436  CL46 HEK-293T C42(0.98)  LDD1640  [11]
 LDCM0437  CL47 HEK-293T C42(1.03); C435(1.20); C438(1.20)  LDD1641  [11]
 LDCM0438  CL48 HEK-293T C42(1.04)  LDD1642  [11]
 LDCM0439  CL49 HEK-293T C561(1.34); C42(0.92)  LDD1643  [11]
 LDCM0440  CL5 HCT 116 C375(1.23); C380(1.23)  LDD0757  [5]
 LDCM0441  CL50 HEK-293T C561(1.57); C42(1.02)  LDD1645  [11]
 LDCM0443  CL52 HEK-293T C42(0.99)  LDD1646  [11]
 LDCM0444  CL53 HEK-293T C561(1.10); C42(0.95)  LDD1647  [11]
 LDCM0445  CL54 HEK-293T C42(0.72)  LDD1648  [11]
 LDCM0446  CL55 HEK-293T C561(1.62); C42(0.99)  LDD1649  [11]
 LDCM0447  CL56 HEK-293T C42(1.08)  LDD1650  [11]
 LDCM0448  CL57 HEK-293T C561(1.56); C42(0.84)  LDD1651  [11]
 LDCM0449  CL58 HEK-293T C42(1.02)  LDD1652  [11]
 LDCM0450  CL59 HEK-293T C42(0.99); C435(1.16); C438(1.16)  LDD1653  [11]
 LDCM0451  CL6 HCT 116 C375(1.29); C380(1.29)  LDD0768  [5]
 LDCM0452  CL60 HEK-293T C42(1.00)  LDD1655  [11]
 LDCM0453  CL61 HCT 116 C375(0.91); C380(0.91)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C375(0.84); C380(0.84)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C375(1.00); C380(1.00)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C375(0.91); C380(0.91)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C375(0.95); C380(0.95)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C375(0.98); C380(0.98)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C375(1.05); C380(1.05)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C375(1.19); C380(1.19)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C375(0.93); C380(0.93)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C375(1.17); C380(1.17)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C375(0.98); C380(0.98)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C375(1.09); C380(1.09)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C375(0.97); C380(0.97)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C375(0.89); C380(0.89)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C375(0.97); C380(0.97)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C375(0.95); C380(0.95)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C375(0.89); C380(0.89)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C375(0.91); C380(0.91)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C375(0.94); C380(0.94)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C375(1.03); C380(1.03)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C375(1.02); C380(1.02)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C375(1.00); C380(1.00)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C375(0.86); C380(0.86)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C375(0.89); C380(0.89)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C375(0.89); C380(0.89)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C375(0.87); C380(0.87)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C375(0.76); C380(0.76)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C375(0.90); C380(0.90)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C375(0.95); C380(0.95)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C375(0.72); C380(0.72)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C375(1.01); C380(1.01)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C375(0.61); C380(0.61)  LDD0802  [5]
 LDCM0486  CL91 HCT 116 C375(1.19); C380(1.19)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C375(0.92); C380(0.92)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C375(1.08); C380(1.08)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C375(1.16); C380(1.16)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C375(0.94); C380(0.94)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C375(1.19); C380(1.19)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C375(1.17); C380(1.17)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C375(1.16); C380(1.16)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C375(1.14); C380(1.14)  LDD0811  [5]
 LDCM0495  E2913 HEK-293T C42(0.92)  LDD1698  [11]
 LDCM0468  Fragment33 HCT 116 C375(0.88); C380(0.88)  LDD0785  [5]
 LDCM0427  Fragment51 HEK-293T C375(1.18)  LDD1025  [5]
 LDCM0022  KB02 HCT 116 C42(1.65)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C42(1.07)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C42(2.12)  LDD0082  [5]
 LDCM0109  NEM HeLa N.A.  LDD0227  [4]
 LDCM0021  THZ1 HCT 116 C375(1.73); C380(1.73)  LDD2173  [5]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
10 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
11 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402