Details of the Target

General Information of Target

Target ID LDTP14732
Target Name Endoribonuclease YbeY (YBEY)
Gene Name YBEY
Gene ID 54059
Synonyms
C21orf57; Endoribonuclease YbeY; EC 3.1.-.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEIHNGGELCDFMENGEIFSEHSCLNAHMGTENTGDTYDCDEYGENFPMLHNSAPAGET
LSVLNQCRKAFSLPPNVHQRTWIGDKSFEYSDCEEAFVDQSHLQANRITHNGETLYEQKQ
CGRAFTYSTSHAVSVKMHTVEKPYECKECGKFFRYSSYLNSHMRTHTGEKPYECKECGKC
FTVSSHLVEHVRIHTGEKPYQCKECGRAFAGRSGLTKHVRIHTGEKPYECNECGKAYNRF
YLLTEHFKTHTEEKPFECKVCGKSFRSSSCLKNHFRIHTGIKPYKCKECGKAFTVSSSLH
NHVKIHTGEKPYECKDCGKAFATSSQLIEHIRTHTGEKPYICKECGKTFRASSHLQKHVR
IHTGEKPYICNECGKAYNRFYLLTKHLKTH
Target Bioclass
Enzyme
Family
Endoribonuclease YbeY family
Subcellular location
Nucleus
Function Single strand-specific metallo-endoribonuclease involved in rRNA maturation.
Uniprot ID
P58557
Ensemble ID
ENST00000329319.7
HGNC ID
HGNC:1299

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL78 SNV: p.R161L .
P31FUJ SNV: p.W134L .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0222  [1]
DBIA
 Probe Info  		C41(0.81)  LDD0532  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [4]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [3]
IPM
 Probe Info  		N.A.  LDD2156  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C102(20.00)  LDD0372  [6]
 LDCM0214  AC1 HEK-293T C41(0.94)  LDD1507  [7]
 LDCM0215  AC10 HCT 116 C41(0.81)  LDD0532  [2]
 LDCM0226  AC11 HCT 116 C41(0.80)  LDD0543  [2]
 LDCM0230  AC113 HCT 116 C41(0.98)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C41(0.87)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C41(0.97)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C41(0.89)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C41(1.00)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C41(0.91)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C41(0.87)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C41(0.78)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C41(0.93)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C41(0.83)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C41(0.99)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C41(0.89)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C41(0.91)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C41(0.96)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C41(1.07)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C41(1.19)  LDD0562  [2]
 LDCM0259  AC14 HCT 116 C41(0.84)  LDD0576  [2]
 LDCM0263  AC143 HCT 116 C41(0.94)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C41(0.95)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C41(0.83)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C41(0.96)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C41(1.13)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C41(1.30)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C41(1.05)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C41(0.84)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C41(0.81)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C41(0.82)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C41(0.91)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C41(1.48)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C41(0.91)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C41(1.13)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C41(1.02)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C41(1.07)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C41(0.71)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C41(0.66)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C41(0.72)  LDD0595  [2]
 LDCM0279  AC2 HEK-293T C41(0.99)  LDD1518  [7]
 LDCM0280  AC20 HCT 116 C41(0.75)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C41(0.70)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C41(0.72)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C41(0.67)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C41(0.79)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C41(0.86)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C41(0.93)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C41(0.97)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C41(0.84)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C41(0.92)  LDD0606  [2]
 LDCM0290  AC3 HEK-293T C41(1.00)  LDD1529  [7]
 LDCM0291  AC30 HCT 116 C41(0.93)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C41(0.96)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C41(0.98)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C41(0.95)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C41(1.02)  LDD0612  [2]
 LDCM0296  AC35 HEK-293T C41(1.01)  LDD1535  [7]
 LDCM0297  AC36 HEK-293T C41(1.11)  LDD1536  [7]
 LDCM0298  AC37 HEK-293T C41(1.01)  LDD1537  [7]
 LDCM0299  AC38 HEK-293T C41(1.05); C102(1.09)  LDD1538  [7]
 LDCM0300  AC39 HEK-293T C41(0.98)  LDD1539  [7]
 LDCM0301  AC4 HEK-293T C41(1.04)  LDD1540  [7]
 LDCM0302  AC40 HEK-293T C41(0.96)  LDD1541  [7]
 LDCM0303  AC41 HEK-293T C41(0.93)  LDD1542  [7]
 LDCM0304  AC42 HEK-293T C41(1.00)  LDD1543  [7]
 LDCM0305  AC43 HEK-293T C41(1.03)  LDD1544  [7]
 LDCM0306  AC44 HEK-293T C41(1.07)  LDD1545  [7]
 LDCM0307  AC45 HEK-293T C41(1.02)  LDD1546  [7]
 LDCM0308  AC46 HCT 116 C41(0.97)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C41(1.02)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C41(1.25)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C41(1.39)  LDD0628  [2]
 LDCM0312  AC5 HEK-293T C41(1.00)  LDD1551  [7]
 LDCM0313  AC50 HCT 116 C41(1.22)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C41(0.97)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C41(0.95)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C41(1.20)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C41(1.14)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C41(1.38)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C41(1.70)  LDD0636  [2]
 LDCM0320  AC57 HEK-293T C41(0.98)  LDD1559  [7]
 LDCM0321  AC58 HEK-293T C41(1.00)  LDD1560  [7]
 LDCM0322  AC59 HEK-293T C41(0.94)  LDD1561  [7]
 LDCM0323  AC6 HCT 116 C41(0.81)  LDD0640  [2]
 LDCM0324  AC60 HEK-293T C41(1.00)  LDD1563  [7]
 LDCM0325  AC61 HEK-293T C41(0.97)  LDD1564  [7]
 LDCM0326  AC62 HEK-293T C41(0.99); C102(0.90)  LDD1565  [7]
 LDCM0327  AC63 HEK-293T C41(0.97)  LDD1566  [7]
 LDCM0328  AC64 HEK-293T C41(0.92)  LDD1567  [7]
 LDCM0332  AC68 HCT 116 C41(1.12)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C41(1.05)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C41(0.82)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C41(1.05)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C41(0.99)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C41(0.91)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C41(1.37)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C41(1.23)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C41(1.40)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C41(1.02)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C41(1.09)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C41(0.94)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C41(1.14)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C41(0.83)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C41(0.98)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C41(0.82)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C41(1.43)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C41(0.98)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C41(1.05)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C41(0.92)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C41(1.09)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C41(1.03)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C41(1.25)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C41(1.16)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C41(1.15)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C41(1.11)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C41(1.00)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C41(0.95)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C41(1.12)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C41(1.00)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C41(0.92)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C41(1.12)  LDD0681  [2]
 LDCM0248  AKOS034007472 HCT 116 C41(0.98)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C41(0.80)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C41(0.85)  LDD0592  [2]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [1]
 LDCM0367  CL1 HEK-293T C41(1.08)  LDD1571  [7]
 LDCM0368  CL10 HEK-293T C41(1.01); C102(0.99)  LDD1572  [7]
 LDCM0369  CL100 HEK-293T C41(1.01)  LDD1573  [7]
 LDCM0370  CL101 HCT 116 C41(0.84)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C41(0.86)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C41(0.86)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C41(0.84)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C41(0.79)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C41(0.87)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C41(0.84)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C41(0.95)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C41(0.73)  LDD0695  [2]
 LDCM0379  CL11 HEK-293T C41(1.00)  LDD1583  [7]
 LDCM0380  CL110 HCT 116 C41(0.78)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C41(0.71)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C41(0.82)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C41(0.82)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C41(0.80)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C41(0.90)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C41(0.98)  LDD0703  [2]
 LDCM0387  CL117 HEK-293T C41(1.00)  LDD1591  [7]
 LDCM0388  CL118 HEK-293T C41(1.03)  LDD1592  [7]
 LDCM0389  CL119 HEK-293T C41(1.09)  LDD1593  [7]
 LDCM0390  CL12 HEK-293T C41(1.08)  LDD1594  [7]
 LDCM0391  CL120 HEK-293T C41(1.03)  LDD1595  [7]
 LDCM0392  CL121 HCT 116 C41(1.13)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C41(1.24)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C41(1.21)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C41(1.41)  LDD0712  [2]
 LDCM0396  CL125 HEK-293T C41(0.98)  LDD1600  [7]
 LDCM0397  CL126 HEK-293T C41(0.92)  LDD1601  [7]
 LDCM0398  CL127 HEK-293T C41(0.97)  LDD1602  [7]
 LDCM0399  CL128 HEK-293T C41(1.01)  LDD1603  [7]
 LDCM0400  CL13 HEK-293T C41(1.00)  LDD1604  [7]
 LDCM0401  CL14 HEK-293T C41(0.97)  LDD1605  [7]
 LDCM0402  CL15 HEK-293T C41(1.07)  LDD1606  [7]
 LDCM0403  CL16 HEK-293T C41(1.10)  LDD1607  [7]
 LDCM0404  CL17 HEK-293T C41(1.01)  LDD1608  [7]
 LDCM0405  CL18 HEK-293T C41(1.11)  LDD1609  [7]
 LDCM0406  CL19 HEK-293T C41(1.13)  LDD1610  [7]
 LDCM0407  CL2 HEK-293T C41(0.94)  LDD1611  [7]
 LDCM0408  CL20 HEK-293T C41(1.16)  LDD1612  [7]
 LDCM0409  CL21 HEK-293T C41(0.97)  LDD1613  [7]
 LDCM0410  CL22 HEK-293T C41(1.08); C102(1.07)  LDD1614  [7]
 LDCM0411  CL23 HEK-293T C41(1.05)  LDD1615  [7]
 LDCM0412  CL24 HEK-293T C41(1.18)  LDD1616  [7]
 LDCM0413  CL25 HEK-293T C41(0.97)  LDD1617  [7]
 LDCM0414  CL26 HEK-293T C41(0.97)  LDD1618  [7]
 LDCM0415  CL27 HEK-293T C41(1.03)  LDD1619  [7]
 LDCM0416  CL28 HEK-293T C41(1.04)  LDD1620  [7]
 LDCM0417  CL29 HEK-293T C41(0.98)  LDD1621  [7]
 LDCM0418  CL3 HEK-293T C41(1.07)  LDD1622  [7]
 LDCM0419  CL30 HEK-293T C41(0.98)  LDD1623  [7]
 LDCM0420  CL31 HCT 116 C41(1.03)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C41(0.96)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C41(1.01)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C41(1.16)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C41(0.97)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C41(1.04)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C41(1.15)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C41(1.13)  LDD0745  [2]
 LDCM0429  CL4 HEK-293T C41(0.98)  LDD1633  [7]
 LDCM0430  CL40 HCT 116 C41(1.02)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C41(1.05)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C41(1.02)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C41(1.10)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C41(1.01)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C41(1.17)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C41(0.89)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C41(0.85)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C41(0.83)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C41(0.83)  LDD0756  [2]
 LDCM0440  CL5 HEK-293T C41(1.05)  LDD1644  [7]
 LDCM0441  CL50 HCT 116 C41(0.83)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C41(0.82)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C41(0.96)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C41(0.86)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C41(0.80)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C41(0.83)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C41(0.82)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C41(0.89)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C41(0.93)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C41(0.86)  LDD0767  [2]
 LDCM0451  CL6 HEK-293T C41(1.09)  LDD1654  [7]
 LDCM0452  CL60 HCT 116 C41(0.79)  LDD0769  [2]
 LDCM0453  CL61 HEK-293T C41(1.08)  LDD1656  [7]
 LDCM0454  CL62 HEK-293T C41(1.00)  LDD1657  [7]
 LDCM0455  CL63 HEK-293T C41(1.00)  LDD1658  [7]
 LDCM0456  CL64 HEK-293T C41(1.01)  LDD1659  [7]
 LDCM0457  CL65 HEK-293T C41(0.96)  LDD1660  [7]
 LDCM0458  CL66 HEK-293T C41(0.96)  LDD1661  [7]
 LDCM0459  CL67 HEK-293T C41(1.09)  LDD1662  [7]
 LDCM0460  CL68 HEK-293T C41(1.05)  LDD1663  [7]
 LDCM0461  CL69 HEK-293T C41(1.03)  LDD1664  [7]
 LDCM0462  CL7 HEK-293T C41(1.07)  LDD1665  [7]
 LDCM0463  CL70 HEK-293T C41(0.95); C102(0.91)  LDD1666  [7]
 LDCM0464  CL71 HEK-293T C41(0.89)  LDD1667  [7]
 LDCM0465  CL72 HEK-293T C41(1.02)  LDD1668  [7]
 LDCM0466  CL73 HEK-293T C41(1.00)  LDD1669  [7]
 LDCM0467  CL74 HEK-293T C41(0.96)  LDD1670  [7]
 LDCM0469  CL76 HEK-293T C41(1.07)  LDD1672  [7]
 LDCM0470  CL77 HEK-293T C41(0.93)  LDD1673  [7]
 LDCM0471  CL78 HEK-293T C41(1.03)  LDD1674  [7]
 LDCM0472  CL79 HEK-293T C41(1.12)  LDD1675  [7]
 LDCM0473  CL8 HEK-293T C41(1.07)  LDD1676  [7]
 LDCM0474  CL80 HEK-293T C41(1.08)  LDD1677  [7]
 LDCM0475  CL81 HEK-293T C41(0.99)  LDD1678  [7]
 LDCM0476  CL82 HEK-293T C41(0.92); C102(1.14)  LDD1679  [7]
 LDCM0477  CL83 HEK-293T C41(0.95)  LDD1680  [7]
 LDCM0478  CL84 HEK-293T C41(1.04)  LDD1681  [7]
 LDCM0479  CL85 HEK-293T C41(1.00)  LDD1682  [7]
 LDCM0480  CL86 HEK-293T C41(0.97)  LDD1683  [7]
 LDCM0481  CL87 HEK-293T C41(1.07)  LDD1684  [7]
 LDCM0482  CL88 HEK-293T C41(1.13)  LDD1685  [7]
 LDCM0483  CL89 HEK-293T C41(1.05)  LDD1686  [7]
 LDCM0484  CL9 HEK-293T C41(0.98)  LDD1687  [7]
 LDCM0485  CL90 HEK-293T C41(0.96)  LDD1688  [7]
 LDCM0486  CL91 HEK-293T C41(1.01)  LDD1689  [7]
 LDCM0487  CL92 HEK-293T C41(1.12)  LDD1690  [7]
 LDCM0488  CL93 HEK-293T C41(0.95)  LDD1691  [7]
 LDCM0489  CL94 HEK-293T C41(1.00); C102(1.01)  LDD1692  [7]
 LDCM0490  CL95 HEK-293T C41(0.97)  LDD1693  [7]
 LDCM0491  CL96 HEK-293T C41(1.04)  LDD1694  [7]
 LDCM0492  CL97 HEK-293T C41(1.06)  LDD1695  [7]
 LDCM0493  CL98 HEK-293T C41(0.92)  LDD1696  [7]
 LDCM0494  CL99 HEK-293T C41(0.36)  LDD1697  [7]
 LDCM0495  E2913 HEK-293T C41(1.08)  LDD1698  [7]
 LDCM0625  F8 Ramos C41(0.58)  LDD2187  [8]
 LDCM0572  Fragment10 Ramos C41(0.52)  LDD2189  [8]
 LDCM0573  Fragment11 Ramos C41(0.34)  LDD2190  [8]
 LDCM0574  Fragment12 Ramos C41(0.86)  LDD2191  [8]
 LDCM0575  Fragment13 Ramos C41(0.81)  LDD2192  [8]
 LDCM0576  Fragment14 Ramos C41(1.18)  LDD2193  [8]
 LDCM0579  Fragment20 Ramos C41(0.82)  LDD2194  [8]
 LDCM0582  Fragment23 Ramos C41(1.25)  LDD2196  [8]
 LDCM0586  Fragment28 Ramos C41(0.94)  LDD2198  [8]
 LDCM0588  Fragment30 Ramos C41(0.58)  LDD2199  [8]
 LDCM0589  Fragment31 Ramos C41(0.81)  LDD2200  [8]
 LDCM0590  Fragment32 Ramos C41(0.47)  LDD2201  [8]
 LDCM0468  Fragment33 HEK-293T C41(0.96)  LDD1671  [7]
 LDCM0596  Fragment38 Ramos C41(0.42)  LDD2203  [8]
 LDCM0566  Fragment4 Ramos C41(0.85)  LDD2184  [8]
 LDCM0427  Fragment51 HCT 116 C41(1.12)  LDD0744  [2]
 LDCM0610  Fragment52 Ramos C41(0.53)  LDD2204  [8]
 LDCM0614  Fragment56 Ramos C41(0.44)  LDD2205  [8]
 LDCM0569  Fragment7 Ramos C41(0.53)  LDD2186  [8]
 LDCM0571  Fragment9 Ramos C41(0.86)  LDD2188  [8]
 LDCM0022  KB02 HEK-293T C41(1.00)  LDD1492  [7]
 LDCM0023  KB03 HEK-293T C41(0.99)  LDD1497  [7]
 LDCM0024  KB05 HMCB C41(2.38)  LDD3312  [9]
 LDCM0109  NEM HeLa H71(0.00); H69(0.00)  LDD0227  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
9 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840