Details of the Target

General Information of Target

Target ID LDTP10507
Target Name Zinc finger protein 512B (ZNF512B)
Gene Name ZNF512B
Gene ID 57473
Synonyms
KIAA1196; Zinc finger protein 512B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK
TESHHKAK
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q96KM6
Ensemble ID
ENST00000369888.6
HGNC ID
HGNC:29212

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C58(2.48)  LDD0168  [1]
DBIA
 Probe Info  		C752(1.15); C756(1.15); C757(1.15); C596(0.99)  LDD0078  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [3]
NAIA_4
 Probe Info  		N.A.  LDD2226  [4]
NAIA_5
 Probe Info  		C58(0.00); C6(0.00)  LDD2224  [4]
TFBX
 Probe Info  		C6(0.00); C58(0.00)  LDD0027  [5]
ENE
 Probe Info  		N.A.  LDD0006  [6]
IPM
 Probe Info  		C757(0.00); C321(0.00)  LDD0005  [6]
VSF
 Probe Info  		C6(0.00); C58(0.00)  LDD0007  [6]
Phosphinate-6
 Probe Info  		C58(0.00); C321(0.00); C6(0.00)  LDD0018  [7]
W1
 Probe Info  		N.A.  LDD0236  [8]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C218
 Probe Info  		10.85  LDD1892  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C58(2.48)  LDD0168  [1]
 LDCM0026  4SU-RNA+native RNA HEK-293T C58(7.05)  LDD0169  [1]
 LDCM0214  AC1 HCT 116 C129(1.15)  LDD0531  [2]
 LDCM0215  AC10 HEK-293T C129(0.62); C756(1.35); C757(1.04)  LDD0813  [2]
 LDCM0216  AC100 HEK-293T C129(1.01); C756(1.07)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C129(1.33); C756(0.95)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C129(1.38); C756(0.98)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C129(0.87); C756(0.90)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C129(0.93); C756(0.88)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C129(0.97); C756(1.46)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C129(1.24); C756(1.53)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C129(1.26); C756(0.93)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C129(1.16); C756(1.33)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C129(1.10); C756(0.99)  LDD0823  [2]
 LDCM0226  AC11 HEK-293T C129(0.58); C756(1.51); C757(0.98)  LDD0824  [2]
 LDCM0227  AC110 HEK-293T C129(1.47); C756(0.85)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C129(1.49); C756(0.75)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C129(1.27); C756(0.73)  LDD0827  [2]
 LDCM0230  AC113 HEK-293T C756(1.17)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C756(1.13)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C756(0.79)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C756(1.05)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C756(0.86)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C756(0.92)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C756(0.93)  LDD0834  [2]
 LDCM0237  AC12 HEK-293T C129(0.76); C756(0.94); C757(0.98)  LDD0835  [2]
 LDCM0238  AC120 HEK-293T C756(0.91)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C756(0.66)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C756(0.70)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C756(0.87)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C756(0.75)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C756(0.82)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C756(0.62)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C756(0.74)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C618(0.99); C623(0.99); C752(1.08); C757(1.08)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C618(1.28); C623(1.28); C752(1.19); C757(1.19)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C618(2.41); C623(2.41); C752(1.22); C757(1.22)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C618(0.77); C623(0.77); C752(1.01); C757(1.01)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C618(1.43); C623(1.43); C752(1.27); C757(1.27)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C618(1.15); C623(1.15); C752(1.37); C757(1.37)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C618(0.98); C623(0.98); C752(1.05); C757(1.05)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C618(0.82); C623(0.82); C752(1.00); C757(1.00)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C618(2.45); C623(2.45); C752(0.86); C757(0.86)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C618(1.03); C623(1.03); C752(1.04); C757(1.04)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C618(0.91); C623(0.91); C752(0.97); C757(0.97)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C618(1.15); C623(1.15); C752(1.07); C757(1.07)  LDD0856  [2]
 LDCM0259  AC14 HEK-293T C129(0.74); C756(1.25); C757(1.10)  LDD0857  [2]
 LDCM0260  AC140 HEK-293T C618(1.06); C623(1.06); C752(1.01); C757(1.01)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C618(0.99); C623(0.99); C752(1.10); C757(1.10)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C618(1.24); C623(1.24); C752(1.00); C757(1.00)  LDD0860  [2]
 LDCM0263  AC143 HCT 116 C129(1.10)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C129(0.88)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C129(0.80)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C129(0.94)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C129(0.91)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C129(0.86)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C129(0.83)  LDD0586  [2]
 LDCM0270  AC15 HEK-293T C129(0.51); C756(0.69); C757(1.20)  LDD0868  [2]
 LDCM0271  AC150 HCT 116 C129(0.71)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C129(0.95)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C129(0.74)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C129(1.01)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C129(0.90)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C129(0.81)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C129(0.85)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C129(0.72)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C129(1.14)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C129(0.95)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C129(1.02)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C129(1.24)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C129(0.70)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C129(0.90)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C129(0.80)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C129(0.91)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C129(0.94)  LDD0601  [2]
 LDCM0285  AC25 HEK-293T C756(0.81); C757(1.26)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C756(0.84); C757(1.03)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C756(0.87); C757(1.10)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C756(0.70); C757(1.05)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C756(0.88); C757(1.05)  LDD0887  [2]
 LDCM0290  AC3 HCT 116 C129(1.99)  LDD0607  [2]
 LDCM0291  AC30 HEK-293T C756(0.82); C757(1.00)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C756(1.20); C757(1.17)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C756(0.89); C757(1.17)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C756(0.85); C757(1.04)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C756(0.94); C757(0.96)  LDD0893  [2]
 LDCM0296  AC35 HEK-293T C756(1.25)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C756(0.95)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C756(1.18)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C756(0.89)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C756(1.02)  LDD0898  [2]
 LDCM0301  AC4 HCT 116 C129(1.48)  LDD0618  [2]
 LDCM0302  AC40 HEK-293T C756(0.96)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C756(0.95)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C756(1.00)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C756(0.88)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C756(0.94)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C756(1.05)  LDD0905  [2]
 LDCM0308  AC46 HEK-293T C752(1.09); C756(1.27); C757(1.09)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C752(1.08); C756(1.35); C757(1.08)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C752(1.21); C756(1.17); C757(1.21)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C752(1.13); C756(1.10); C757(1.13)  LDD0909  [2]
 LDCM0312  AC5 HCT 116 C129(1.81)  LDD0629  [2]
 LDCM0313  AC50 HEK-293T C752(0.97); C756(1.04); C757(0.97)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C752(1.06); C756(0.98); C757(1.06)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C752(1.02); C756(0.97); C757(1.02)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C752(0.85); C756(0.95); C757(0.85)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C752(1.20); C756(1.08); C757(1.20)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C752(0.98); C756(1.09); C757(0.98)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C752(1.28); C756(1.24); C757(1.28)  LDD0917  [2]
 LDCM0320  AC57 HEK-293T C129(0.78); C618(1.00); C623(1.00)  LDD0918  [2]
 LDCM0321  AC58 HEK-293T C129(1.01); C618(0.93); C623(0.93)  LDD0919  [2]
 LDCM0322  AC59 HEK-293T C129(0.87); C618(1.08); C623(1.08)  LDD0920  [2]
 LDCM0323  AC6 HEK-293T C129(1.09); C756(0.89); C757(0.99)  LDD0921  [2]
 LDCM0324  AC60 HEK-293T C129(0.84); C618(1.56); C623(1.56)  LDD0922  [2]
 LDCM0325  AC61 HEK-293T C129(1.07); C618(0.88); C623(0.88)  LDD0923  [2]
 LDCM0326  AC62 HEK-293T C129(1.08); C618(0.79); C623(0.79)  LDD0924  [2]
 LDCM0327  AC63 HEK-293T C129(1.21); C618(0.77); C623(0.77)  LDD0925  [2]
 LDCM0328  AC64 HEK-293T C129(1.03); C618(0.76); C623(0.76)  LDD0926  [2]
 LDCM0329  AC65 HEK-293T C129(0.88); C618(0.80); C623(0.80)  LDD0927  [2]
 LDCM0330  AC66 HEK-293T C129(1.05); C618(0.89); C623(0.89)  LDD0928  [2]
 LDCM0331  AC67 HEK-293T C129(1.05); C618(0.82); C623(0.82)  LDD0929  [2]
 LDCM0332  AC68 HEK-293T C129(1.29); C618(0.96); C623(0.96); C752(0.91)  LDD0930  [2]
 LDCM0333  AC69 HEK-293T C129(1.30); C618(0.69); C623(0.69); C752(0.94)  LDD0931  [2]
 LDCM0334  AC7 HEK-293T C129(0.73); C756(0.74); C757(0.83)  LDD0932  [2]
 LDCM0335  AC70 HEK-293T C129(0.80); C618(0.80); C623(0.80); C752(0.87)  LDD0933  [2]
 LDCM0336  AC71 HEK-293T C129(0.85); C618(1.16); C623(1.16); C752(0.97)  LDD0934  [2]
 LDCM0337  AC72 HEK-293T C129(0.93); C618(0.95); C623(0.95); C752(0.95)  LDD0935  [2]
 LDCM0338  AC73 HEK-293T C129(0.52); C618(1.04); C623(1.04); C752(1.10)  LDD0936  [2]
 LDCM0339  AC74 HEK-293T C129(0.82); C618(1.02); C623(1.02); C752(0.78)  LDD0937  [2]
 LDCM0340  AC75 HEK-293T C129(0.73); C618(1.26); C623(1.26); C752(0.92)  LDD0938  [2]
 LDCM0341  AC76 HEK-293T C129(1.26); C618(1.41); C623(1.41); C752(1.00)  LDD0939  [2]
 LDCM0342  AC77 HEK-293T C129(1.02); C618(1.39); C623(1.39); C752(0.83)  LDD0940  [2]
 LDCM0343  AC78 HEK-293T C129(1.02); C618(2.02); C623(2.02); C752(1.00)  LDD0941  [2]
 LDCM0344  AC79 HEK-293T C129(0.88); C618(1.11); C623(1.11); C752(1.01)  LDD0942  [2]
 LDCM0345  AC8 HEK-293T C129(0.65); C756(0.92); C757(0.94)  LDD0943  [2]
 LDCM0346  AC80 HEK-293T C129(0.87); C618(1.42); C623(1.42); C752(1.14)  LDD0944  [2]
 LDCM0347  AC81 HEK-293T C129(1.26); C618(1.52); C623(1.52); C752(1.26)  LDD0945  [2]
 LDCM0348  AC82 HEK-293T C129(1.30); C618(1.55); C623(1.55); C752(0.98)  LDD0946  [2]
 LDCM0349  AC83 HCT 116 C129(1.24)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C129(1.22)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C129(1.18)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C129(1.01)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C129(1.15)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C129(1.07)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C129(0.97)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C129(1.34)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C129(0.90)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C129(1.30)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C129(1.12)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C129(1.22)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C129(1.08)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C129(0.95)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C129(1.30)  LDD0681  [2]
 LDCM0365  AC98 HEK-293T C129(0.98); C756(1.28)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C129(1.07); C756(0.96)  LDD0964  [2]
 LDCM0248  AKOS034007472 HEK-293T C129(0.76); C756(0.84); C757(1.06)  LDD0846  [2]
 LDCM0356  AKOS034007680 HEK-293T C129(0.68); C756(0.88); C757(1.06)  LDD0954  [2]
 LDCM0275  AKOS034007705 HEK-293T C129(0.85); C756(0.69); C757(1.01)  LDD0873  [2]
 LDCM0020  ARS-1620 HCC44 C752(1.15); C756(1.15); C757(1.15); C596(0.99)  LDD0078  [2]
 LDCM0367  CL1 HCT 116 C129(1.04)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C129(1.48)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C129(1.26)  LDD0686  [2]
 LDCM0370  CL101 HEK-293T C129(1.19); C756(0.66); C757(0.94)  LDD0968  [2]
 LDCM0371  CL102 HEK-293T C129(0.81); C756(0.73); C757(1.01)  LDD0969  [2]
 LDCM0372  CL103 HEK-293T C129(0.72); C756(0.86); C757(1.07)  LDD0970  [2]
 LDCM0373  CL104 HEK-293T C129(0.80); C756(0.94); C757(1.00)  LDD0971  [2]
 LDCM0374  CL105 HCT 116 C129(0.92)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C129(0.90)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C129(0.90)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C129(0.96)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C129(0.82)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C129(1.12)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C129(0.96)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C129(0.95)  LDD0698  [2]
 LDCM0382  CL112 HEK-293T C756(0.82); C757(0.97)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C756(0.91); C757(1.02)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C756(0.66); C757(1.04)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C756(0.78); C757(1.12)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C756(0.77); C757(1.11)  LDD0984  [2]
 LDCM0387  CL117 HEK-293T C756(1.01)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C756(1.09)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C756(1.01)  LDD0987  [2]
 LDCM0390  CL12 HCT 116 C129(1.11)  LDD0707  [2]
 LDCM0391  CL120 HEK-293T C756(0.97)  LDD0989  [2]
 LDCM0392  CL121 HEK-293T C752(1.08); C756(0.96); C757(1.08)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C752(1.00); C756(1.00); C757(1.00)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C752(1.07); C756(1.09); C757(1.07)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C752(0.84); C756(0.99); C757(0.84)  LDD0993  [2]
 LDCM0396  CL125 HEK-293T C129(1.01); C618(0.96); C623(0.96)  LDD0994  [2]
 LDCM0397  CL126 HEK-293T C129(0.71); C618(0.97); C623(0.97)  LDD0995  [2]
 LDCM0398  CL127 HEK-293T C129(0.86); C618(1.00); C623(1.00)  LDD0996  [2]
 LDCM0399  CL128 HEK-293T C129(0.98); C618(1.06); C623(1.06)  LDD0997  [2]
 LDCM0400  CL13 HCT 116 C129(1.30)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C129(1.10)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C129(0.95)  LDD0719  [2]
 LDCM0403  CL16 HEK-293T C756(0.92)  LDD1001  [2]
 LDCM0404  CL17 HEK-293T C756(0.92)  LDD1002  [2]
 LDCM0405  CL18 HEK-293T C756(0.87)  LDD1003  [2]
 LDCM0406  CL19 HEK-293T C756(0.83)  LDD1004  [2]
 LDCM0407  CL2 HCT 116 C129(1.37)  LDD0724  [2]
 LDCM0408  CL20 HEK-293T C756(0.94)  LDD1006  [2]
 LDCM0409  CL21 HEK-293T C756(0.73)  LDD1007  [2]
 LDCM0410  CL22 HEK-293T C756(0.82)  LDD1008  [2]
 LDCM0411  CL23 HEK-293T C756(1.02)  LDD1009  [2]
 LDCM0412  CL24 HEK-293T C756(1.10)  LDD1010  [2]
 LDCM0413  CL25 HEK-293T C756(0.93)  LDD1011  [2]
 LDCM0414  CL26 HEK-293T C756(1.04)  LDD1012  [2]
 LDCM0415  CL27 HEK-293T C756(1.05)  LDD1013  [2]
 LDCM0416  CL28 HEK-293T C756(1.24)  LDD1014  [2]
 LDCM0417  CL29 HEK-293T C756(1.12)  LDD1015  [2]
 LDCM0418  CL3 HCT 116 C129(1.28)  LDD0735  [2]
 LDCM0419  CL30 HEK-293T C756(0.81)  LDD1017  [2]
 LDCM0420  CL31 HEK-293T C756(0.76)  LDD1018  [2]
 LDCM0421  CL32 HEK-293T C756(0.81)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C756(0.59)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C756(0.76)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C756(0.66)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C756(0.82)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C756(0.59)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C756(0.55)  LDD1026  [2]
 LDCM0429  CL4 HCT 116 C129(1.21)  LDD0746  [2]
 LDCM0430  CL40 HEK-293T C756(0.71)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C756(0.63)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C756(0.58)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C756(0.59)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C756(0.67)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C756(0.65)  LDD1033  [2]
 LDCM0436  CL46 HEK-293T C129(0.68)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C129(0.55)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C129(0.53)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C129(0.52)  LDD1037  [2]
 LDCM0440  CL5 HCT 116 C129(1.24)  LDD0757  [2]
 LDCM0441  CL50 HEK-293T C129(0.75)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C129(0.71)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C129(0.57)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C129(0.63)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C129(0.65)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C129(0.62)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C129(0.69)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C129(0.46)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C129(0.45)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C129(0.43)  LDD1048  [2]
 LDCM0451  CL6 HCT 116 C129(0.97)  LDD0768  [2]
 LDCM0452  CL60 HEK-293T C129(0.93)  LDD1050  [2]
 LDCM0453  CL61 HCT 116 C129(0.91)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C129(0.79)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C129(1.16)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C129(1.12)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C129(0.87)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C129(1.34)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C129(0.82)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C129(1.77)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C129(1.16)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C129(1.52)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C129(0.82)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C129(0.80)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C129(0.62)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C129(0.99)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C129(1.24)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C129(1.61)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C129(1.14)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C129(1.38)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C129(1.46)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C129(1.34)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C129(1.13)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C129(1.25)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C129(0.93)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C129(1.17)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C129(1.35)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C129(1.43)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C129(1.20)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C129(1.13)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C129(1.13)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C129(0.73)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C129(1.01)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C129(0.88)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C129(1.44)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C129(1.09)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C129(0.95)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C129(0.95)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C129(1.05)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C129(1.36)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C129(1.10)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C129(1.78)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C129(1.67)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C129(0.90); C353(1.06); C58(1.11)  LDD1698  [10]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C321(1.44); C757(0.95); C774(0.81)  LDD1702  [11]
 LDCM0468  Fragment33 HCT 116 C129(0.94)  LDD0785  [2]
 LDCM0427  Fragment51 HEK-293T C756(1.01)  LDD1025  [2]
 LDCM0022  KB02 HCT 116 C752(1.65); C596(1.56); C601(1.56); C756(1.67)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C752(2.70); C596(1.59); C601(1.59); C756(2.12)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C752(1.86); C596(1.62); C601(1.62); C756(1.26)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C618(1.02); C623(1.02); C596(1.32); C601(1.32)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
E3 ubiquitin-protein ligase SIAH1 (SIAH1) SINA (Seven in absentia) family Q8IUQ4
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
MyoD family inhibitor (MDFI) MDFI family Q99750
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 143 (ZNF143) GLI C2H2-type zinc-finger protein family P52747
Nucleus accumbens-associated protein 1 (NACC1) . Q96RE7
Other
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Rab GTPase-binding effector protein 1 (RABEP1) Rabaptin family Q15276
LIM domain-containing protein ajuba (AJUBA) Zyxin/ajuba family Q96IF1
Zyxin (ZYX) Zyxin/ajuba family Q15942
Four and a half LIM domains protein 3 (FHL3) . Q13643
TNF receptor-associated factor 1 (TRAF1) . Q13077

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
5 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
8 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
9 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761