Details of the Target

General Information of Target

Target ID LDTP09712
Target Name Ankyrin repeat and SOCS box protein 13 (ASB13)
Gene Name ASB13
Gene ID 79754
Synonyms
Ankyrin repeat and SOCS box protein 13; ASB-13
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAAS
LQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASP
LHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAK
LHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPL
TLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSYN
Target Bioclass
Other
Family
Ankyrin SOCS box (ASB) family
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Uniprot ID
Q8WXK3
Ensemble ID
ENST00000357700.11
HGNC ID
HGNC:19765

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
IGROV1 Deletion: p.C158LfsTer19 .
MFE319 SNV: p.Ter279RextTer34 .
NCIH2172 SNV: p.D84Y .
RKO SNV: p.K237E .
SKOV3 Insertion: p.I83AfsTer21 .
SW403 SNV: p.D147Y .
THP1 SNV: p.L186R .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C246(1.24)  LDD2182  [1]
DBIA
 Probe Info  		C231(0.62)  LDD0532  [2]
TFBX
 Probe Info  		N.A.  LDD0148  [3]
NAIA_5
 Probe Info  		C231(0.00); C246(0.00)  LDD2223  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HCT 116 C231(0.62)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C231(0.50)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C231(0.75)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C231(0.59)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C231(0.84)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C231(0.52)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C231(0.56)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C231(0.68)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C231(0.72)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C231(0.81)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C231(0.65)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C231(0.61)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C231(0.56)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C231(0.91)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C231(0.54)  LDD0546  [2]
 LDCM0230  AC113 PaTu 8988t C231(1.01)  LDD1109  [2]
 LDCM0231  AC114 PaTu 8988t C231(1.16)  LDD1110  [2]
 LDCM0232  AC115 PaTu 8988t C231(1.03)  LDD1111  [2]
 LDCM0233  AC116 PaTu 8988t C231(1.20)  LDD1112  [2]
 LDCM0234  AC117 PaTu 8988t C231(1.03)  LDD1113  [2]
 LDCM0235  AC118 PaTu 8988t C231(0.94)  LDD1114  [2]
 LDCM0236  AC119 PaTu 8988t C231(1.13)  LDD1115  [2]
 LDCM0237  AC12 HCT 116 C231(0.78)  LDD0554  [2]
 LDCM0238  AC120 PaTu 8988t C231(1.03)  LDD1117  [2]
 LDCM0239  AC121 PaTu 8988t C231(1.10)  LDD1118  [2]
 LDCM0240  AC122 PaTu 8988t C231(0.97)  LDD1119  [2]
 LDCM0241  AC123 PaTu 8988t C231(0.88)  LDD1120  [2]
 LDCM0242  AC124 PaTu 8988t C231(1.16)  LDD1121  [2]
 LDCM0243  AC125 PaTu 8988t C231(0.92)  LDD1122  [2]
 LDCM0244  AC126 PaTu 8988t C231(1.09)  LDD1123  [2]
 LDCM0245  AC127 PaTu 8988t C231(1.11)  LDD1124  [2]
 LDCM0246  AC128 PaTu 8988t C231(0.89)  LDD1125  [2]
 LDCM0247  AC129 PaTu 8988t C231(0.87)  LDD1126  [2]
 LDCM0249  AC130 PaTu 8988t C231(0.76)  LDD1128  [2]
 LDCM0250  AC131 PaTu 8988t C231(0.85)  LDD1129  [2]
 LDCM0251  AC132 PaTu 8988t C231(0.85)  LDD1130  [2]
 LDCM0252  AC133 PaTu 8988t C231(1.15)  LDD1131  [2]
 LDCM0253  AC134 PaTu 8988t C231(1.06)  LDD1132  [2]
 LDCM0254  AC135 PaTu 8988t C231(1.17)  LDD1133  [2]
 LDCM0255  AC136 PaTu 8988t C231(1.01)  LDD1134  [2]
 LDCM0256  AC137 PaTu 8988t C231(1.24)  LDD1135  [2]
 LDCM0257  AC138 PaTu 8988t C231(0.84)  LDD1136  [2]
 LDCM0258  AC139 PaTu 8988t C231(0.82)  LDD1137  [2]
 LDCM0259  AC14 HCT 116 C231(0.71)  LDD0576  [2]
 LDCM0260  AC140 PaTu 8988t C231(0.83)  LDD1139  [2]
 LDCM0261  AC141 PaTu 8988t C231(0.80)  LDD1140  [2]
 LDCM0262  AC142 PaTu 8988t C231(0.89)  LDD1141  [2]
 LDCM0263  AC143 HCT 116 C231(0.94)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C231(0.60)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C231(0.72)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C231(0.77)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C231(0.65)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C231(0.72)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C231(0.73)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C231(0.59)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C231(0.61)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C231(0.91)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C231(0.65)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C231(0.84)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C231(0.74)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C231(0.68)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C231(1.31)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C231(1.08)  LDD2161  [2]
 LDCM0276  AC17 PaTu 8988t C231(1.13)  LDD1155  [2]
 LDCM0277  AC18 PaTu 8988t C231(0.74)  LDD1156  [2]
 LDCM0278  AC19 PaTu 8988t C231(1.09)  LDD1157  [2]
 LDCM0280  AC20 PaTu 8988t C231(0.89)  LDD1159  [2]
 LDCM0281  AC21 PaTu 8988t C231(0.95)  LDD1160  [2]
 LDCM0282  AC22 PaTu 8988t C231(0.81)  LDD1161  [2]
 LDCM0283  AC23 PaTu 8988t C231(0.88)  LDD1162  [2]
 LDCM0284  AC24 PaTu 8988t C231(0.74)  LDD1163  [2]
 LDCM0285  AC25 HCT 116 C231(0.88)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C231(0.68)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C231(0.71)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C231(0.61)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C231(0.69)  LDD0606  [2]
 LDCM0291  AC30 HCT 116 C231(0.70)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C231(0.81)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C231(0.65)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C231(0.68)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C231(0.70)  LDD0612  [2]
 LDCM0296  AC35 PaTu 8988t C231(1.29)  LDD1175  [2]
 LDCM0297  AC36 PaTu 8988t C231(1.03)  LDD1176  [2]
 LDCM0298  AC37 PaTu 8988t C231(0.84)  LDD1177  [2]
 LDCM0299  AC38 PaTu 8988t C231(1.07)  LDD1178  [2]
 LDCM0300  AC39 PaTu 8988t C231(0.78)  LDD1179  [2]
 LDCM0302  AC40 PaTu 8988t C231(0.94)  LDD1181  [2]
 LDCM0303  AC41 PaTu 8988t C231(0.81)  LDD1182  [2]
 LDCM0304  AC42 PaTu 8988t C231(0.90)  LDD1183  [2]
 LDCM0305  AC43 PaTu 8988t C231(0.91)  LDD1184  [2]
 LDCM0306  AC44 PaTu 8988t C231(0.95)  LDD1185  [2]
 LDCM0307  AC45 PaTu 8988t C231(0.83)  LDD1186  [2]
 LDCM0320  AC57 HCT 116 C231(0.61)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C231(0.58)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C231(0.68)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C231(0.57)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C231(0.81)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C231(0.66)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C231(0.60)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C231(0.62)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C231(0.64)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C231(0.61)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C231(0.61)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C231(0.57)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C231(1.13)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C231(1.06)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C231(0.75)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C231(0.87)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C231(1.21)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C231(0.99)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C231(1.22)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C231(1.23)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C231(1.26)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C231(1.14)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C231(1.12)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C231(1.07)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C231(1.13)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C231(0.57)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C231(1.13)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C231(1.11)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C231(1.27)  LDD0665  [2]
 LDCM0349  AC83 PaTu 8988t C231(0.98)  LDD1228  [2]
 LDCM0350  AC84 PaTu 8988t C231(0.95)  LDD1229  [2]
 LDCM0351  AC85 PaTu 8988t C231(1.13)  LDD1230  [2]
 LDCM0352  AC86 PaTu 8988t C231(1.09)  LDD1231  [2]
 LDCM0353  AC87 PaTu 8988t C231(1.16)  LDD1232  [2]
 LDCM0354  AC88 PaTu 8988t C231(1.07)  LDD1233  [2]
 LDCM0355  AC89 PaTu 8988t C231(1.03)  LDD1234  [2]
 LDCM0357  AC90 PaTu 8988t C231(1.26)  LDD1236  [2]
 LDCM0358  AC91 PaTu 8988t C231(1.04)  LDD1237  [2]
 LDCM0359  AC92 PaTu 8988t C231(0.98)  LDD1238  [2]
 LDCM0360  AC93 PaTu 8988t C231(1.37)  LDD1239  [2]
 LDCM0361  AC94 PaTu 8988t C231(0.99)  LDD1240  [2]
 LDCM0362  AC95 PaTu 8988t C231(1.09)  LDD1241  [2]
 LDCM0363  AC96 PaTu 8988t C231(1.49)  LDD1242  [2]
 LDCM0364  AC97 PaTu 8988t C231(1.27)  LDD1243  [2]
 LDCM0365  AC98 HCT 116 C231(0.81)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C231(0.74)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C231(1.09)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C231(0.81)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C231(0.77)  LDD0592  [2]
 LDCM0367  CL1 PaTu 8988t C231(0.92)  LDD1246  [2]
 LDCM0368  CL10 PaTu 8988t C231(0.82)  LDD1247  [2]
 LDCM0370  CL101 HCT 116 C231(0.57)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C231(1.11)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C231(1.37)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C231(0.90)  LDD0690  [2]
 LDCM0374  CL105 PaTu 8988t C231(0.87)  LDD1253  [2]
 LDCM0375  CL106 PaTu 8988t C231(0.86)  LDD1254  [2]
 LDCM0376  CL107 PaTu 8988t C231(0.97)  LDD1255  [2]
 LDCM0377  CL108 PaTu 8988t C231(0.82)  LDD1256  [2]
 LDCM0378  CL109 PaTu 8988t C231(0.80)  LDD1257  [2]
 LDCM0379  CL11 PaTu 8988t C231(0.84)  LDD1258  [2]
 LDCM0380  CL110 PaTu 8988t C231(0.89)  LDD1259  [2]
 LDCM0381  CL111 PaTu 8988t C231(0.91)  LDD1260  [2]
 LDCM0382  CL112 HCT 116 C231(0.95)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C231(0.61)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C231(0.87)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C231(0.61)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C231(0.66)  LDD0703  [2]
 LDCM0387  CL117 PaTu 8988t C231(1.39)  LDD1266  [2]
 LDCM0388  CL118 PaTu 8988t C231(1.04)  LDD1267  [2]
 LDCM0389  CL119 PaTu 8988t C231(0.72)  LDD1268  [2]
 LDCM0390  CL12 PaTu 8988t C231(0.81)  LDD1269  [2]
 LDCM0391  CL120 PaTu 8988t C231(0.77)  LDD1270  [2]
 LDCM0396  CL125 HCT 116 C231(0.76)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C231(0.60)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C231(0.69)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C231(0.64)  LDD0716  [2]
 LDCM0400  CL13 PaTu 8988t C231(0.62)  LDD1279  [2]
 LDCM0401  CL14 PaTu 8988t C231(0.76)  LDD1280  [2]
 LDCM0402  CL15 PaTu 8988t C231(0.78)  LDD1281  [2]
 LDCM0403  CL16 HCT 116 C231(0.78)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C231(1.09)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C231(0.83)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C231(0.90)  LDD0723  [2]
 LDCM0407  CL2 PaTu 8988t C231(0.79)  LDD1286  [2]
 LDCM0408  CL20 HCT 116 C231(0.75)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C231(1.17)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C231(1.23)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C231(0.74)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C231(0.89)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C231(0.98)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C231(0.75)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C231(1.01)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C231(0.81)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C231(0.85)  LDD0734  [2]
 LDCM0418  CL3 PaTu 8988t C231(0.78)  LDD1297  [2]
 LDCM0419  CL30 HCT 116 C231(0.72)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C231(0.72)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C231(0.79)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C231(0.96)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C231(0.93)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C231(0.73)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C231(1.01)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C231(1.03)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C231(0.97)  LDD0745  [2]
 LDCM0429  CL4 PaTu 8988t C231(0.93)  LDD1308  [2]
 LDCM0430  CL40 HCT 116 C231(0.78)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C231(0.94)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C231(1.28)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C231(1.09)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C231(1.21)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C231(1.05)  LDD0752  [2]
 LDCM0440  CL5 PaTu 8988t C231(0.76)  LDD1319  [2]
 LDCM0451  CL6 PaTu 8988t C231(0.82)  LDD1330  [2]
 LDCM0453  CL61 HCT 116 C231(0.92)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C231(0.87)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C231(0.83)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C231(0.86)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C231(0.84)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C231(0.82)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C231(0.75)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C231(0.87)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C231(1.18)  LDD0778  [2]
 LDCM0462  CL7 PaTu 8988t C231(0.72)  LDD1341  [2]
 LDCM0463  CL70 HCT 116 C231(0.89)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C231(0.69)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C231(1.02)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C231(0.76)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C231(0.72)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C231(0.86)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C231(0.74)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C231(0.79)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C231(0.71)  LDD0789  [2]
 LDCM0473  CL8 PaTu 8988t C231(0.81)  LDD1352  [2]
 LDCM0474  CL80 HCT 116 C231(0.84)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C231(0.70)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C231(0.85)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C231(0.87)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C231(0.74)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C231(0.75)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C231(0.77)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C231(0.76)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C231(0.75)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C231(0.82)  LDD0800  [2]
 LDCM0484  CL9 PaTu 8988t C231(0.88)  LDD1363  [2]
 LDCM0485  CL90 HCT 116 C231(1.12)  LDD0802  [2]
 LDCM0625  F8 Ramos C246(0.56)  LDD2187  [1]
 LDCM0572  Fragment10 Ramos C246(0.59)  LDD2189  [1]
 LDCM0573  Fragment11 Ramos C246(1.18)  LDD2190  [1]
 LDCM0574  Fragment12 Ramos C246(1.14)  LDD2191  [1]
 LDCM0575  Fragment13 Ramos C246(1.03)  LDD2192  [1]
 LDCM0576  Fragment14 Ramos C246(1.04)  LDD2193  [1]
 LDCM0580  Fragment21 Ramos C246(0.89)  LDD2195  [1]
 LDCM0582  Fragment23 Ramos C246(0.89)  LDD2196  [1]
 LDCM0578  Fragment27 Ramos C246(0.85)  LDD2197  [1]
 LDCM0586  Fragment28 Ramos C246(0.71)  LDD2198  [1]
 LDCM0588  Fragment30 Ramos C246(0.94)  LDD2199  [1]
 LDCM0589  Fragment31 Ramos C246(1.05)  LDD2200  [1]
 LDCM0590  Fragment32 Ramos C246(0.71)  LDD2201  [1]
 LDCM0468  Fragment33 HCT 116 C231(0.76)  LDD0785  [2]
 LDCM0596  Fragment38 Ramos C246(0.77)  LDD2203  [1]
 LDCM0566  Fragment4 Ramos C246(0.78)  LDD2184  [1]
 LDCM0427  Fragment51 HCT 116 C231(0.90)  LDD0744  [2]
 LDCM0610  Fragment52 Ramos C246(1.32)  LDD2204  [1]
 LDCM0614  Fragment56 Ramos C246(1.09)  LDD2205  [1]
 LDCM0569  Fragment7 Ramos C246(1.36)  LDD2186  [1]
 LDCM0571  Fragment9 Ramos C246(1.24)  LDD2188  [1]
 LDCM0022  KB02 Ramos C246(1.24)  LDD2182  [1]
 LDCM0023  KB03 Ramos C246(1.11)  LDD2183  [1]
 LDCM0024  KB05 Ramos C246(3.81)  LDD2185  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Pachytene checkpoint protein 2 homolog (TRIP13) AAA ATPase family Q15645
Kallikrein-6 (KLK6) Peptidase S1 family Q92876
MAP/microtubule affinity-regulating kinase 3 (MARK3) CAMK Ser/Thr protein kinase family P27448
Coagulation factor XIII A chain (F13A1) Transglutaminase family P00488
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Alpha-synuclein (SNCA) Synuclein family P37840
Transcription factor
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
POU domain, class 6, transcription factor 2 (POU6F2) POU transcription factor family P78424
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Pogo transposable element with ZNF domain (POGZ) . Q7Z3K3
Zinc finger protein 581 (ZNF581) . Q9P0T4
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Oxoeicosanoid receptor 1 (OXER1) G-protein coupled receptor 1 family Q8TDS5
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hyaluronan and proteoglycan link protein 2 (HAPLN2) HAPLN family Q9GZV7
Other
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ankyrin repeat and SOCS box protein 9 (ASB9) Ankyrin SOCS box (ASB) family Q96DX5
Ataxin-1 (ATXN1) ATXN1 family P54253
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
Keratin-associated protein 15-1 (KRTAP15-1) PMG family Q3LI76
Protein VAC14 homolog (VAC14) VAC14 family Q08AM6
RING finger protein 11 (RNF11) . Q9Y3C5
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699
TAR DNA-binding protein 43 (TARDBP) . Q13148
Ubiquitin-associated protein 2 (UBAP2) . Q5T6F2

References

1 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264