Details of the Target

General Information of Target

Target ID LDTP07925
Target Name E3 ubiquitin-protein ligase HECW1 (HECW1)
Gene Name HECW1
Gene ID 23072
Synonyms
KIAA0322; NEDL1; E3 ubiquitin-protein ligase HECW1; EC 2.3.2.26; HECT, C2 and WW domain-containing protein 1; HECT-type E3 ubiquitin transferase HECW1; NEDD4-like E3 ubiquitin-protein ligase 1; hNEDL1
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MLLHLCSVKNLYQNRFLGLAAMASPSRNSQSRRRCKEPLRYSYNPDQFHNMDLRGGPHDG
VTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEV
LSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVK
NSAAPIFKSIGADETVQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSI
FPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGK
LSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPDDEEISLSTEPE
SAQIQDSPMNNLMESGSGEPRSEAPESSESWKPEQLGEGSVPDGPGNQSIELSRPAEEAA
VITEAGDQGMVSVGPEGAGELLAQVQKDIQPAPSAEELAEQLDLGEEASALLLEDGEAPA
STKEEPLEEEATTQSRAGREEEEKEQEEEGDVSTLEQGEGRLQLRASVKRKSRPCSLPVS
ELETVIASACGDPETPRTHYIRIHTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGL
SEVDTVAADPSALEEDREEPEGATPGTAHPGHSGGHFPSLANGAAQDGDTHPSTGSESDS
SPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCYSPSCYNGNRFASHTRFS
SVDSAKISESTVFSSQDDEEEENSAFESVPDSMQSPELDPESTNGAGPWQDELAAPSGHV
ERSPEGLESPVAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARID
SHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEED
SGSQSCEQAPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFITN
PEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLEL
PRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEAS
EVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLA
RNHTLREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRC
SPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLL
EGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSAN
DTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDL
EYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYI
ERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTE
YRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIE
KWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE
Target Bioclass
Enzyme
Subcellular location
Cytoplasm
Function
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
Uniprot ID
Q76N89
Ensemble ID
ENST00000395891.7
HGNC ID
HGNC:22195

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
BT549 Substitution: p.V1184T .
CCK81 SNV: p.R1232H .
CMK SNV: p.G622E .
COLO678 SNV: p.T717M .
COLO792 SNV: p.H1150Y .
DETROIT562 Substitution: p.V1184T .
DU145 SNV: p.V528L .
HCT15 SNV: p.S653I; p.A675V; p.T1363A .
HEC1 SNV: p.P768L .
HEC1B SNV: p.P768L .
HS936T SNV: p.G1426E .
HSC3 SNV: p.F733L .
HSC4 SNV: p.A1458V .
IGROV1 SNV: p.D1015G .
Ishikawa (Heraklio) 02 ER Deletion: p.S454VfsTer75 .
JURKAT SNV: p.A1167V; p.T1566A .
KYSE180 SNV: p.P453L .
LS180 SNV: p.P760L .
LS513 SNV: p.E586K .
MIAPACA2 SNV: p.H1337Y .
MOLT4 SNV: p.A623T .
NALM6 SNV: p.D46N; p.A147T .
NCIH1048 SNV: p.R1057P .
NCIH1155 SNV: p.Q197Ter; p.E488Ter .
NCIH2172 SNV: p.G1087V .
NCIH358 SNV: p.A675V .
RKO SNV: p.T894A .
RPMI7951 Substitution: p.V1184T .
SKMEL2 SNV: p.E1306G .
SKNMC Substitution: p.V1184T .
SNU1 SNV: p.T1595I .
SW1783 SNV: p.V722M .
SW837 SNV: p.D475H .
TE1 SNV: p.E935Q .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C1574(1.47)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C1574(1.47)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C1574(1.36)  LDD0532  [1]
 LDCM0226  AC11 HCT 116 C1574(1.45)  LDD0543  [1]
 LDCM0230  AC113 HCT 116 C1574(1.01)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C1574(1.38)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C1574(1.64)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C1574(1.38)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C1574(1.17)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C1574(1.38)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C1574(1.37)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C1574(1.26)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C1574(1.45)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C1574(1.13)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C1574(0.97)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C1574(1.09)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C1574(1.08)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C1574(1.13)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C1574(1.14)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C1574(1.26)  LDD0562  [1]
 LDCM0259  AC14 HCT 116 C1574(1.40)  LDD0576  [1]
 LDCM0263  AC143 HCT 116 C1574(1.36)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C1574(1.81)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C1574(1.29)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C1574(1.09)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C1574(1.77)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C1574(1.69)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C1574(1.67)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C1574(1.37)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C1574(1.28)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C1574(1.28)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C1574(1.71)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C1574(1.75)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C1574(1.65)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C1574(1.22)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C1574(1.14)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C1574(0.98)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C1574(1.15)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C1574(1.88)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C1574(1.05)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C1574(1.25)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C1574(0.98)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C1574(1.10)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C1574(1.05)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C1574(1.06)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C1574(1.11)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C1574(1.07)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C1574(1.30)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C1574(1.25)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C1574(1.38)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C1574(1.18)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C1574(1.38)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C1574(1.39)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C1574(1.31)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C1574(1.57)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C1574(1.52)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C1574(1.56)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C1574(1.01)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C1574(1.02)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C1574(1.03)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C1574(0.94)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C1574(1.05)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C1574(1.51)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C1574(1.19)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C1574(1.11)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C1574(1.05)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C1574(1.18)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C1574(1.17)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C1574(1.23)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C1574(1.08)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C1574(1.08)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C1574(0.93)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C1574(1.41)  LDD0628  [1]
 LDCM0312  AC5 HCT 116 C1574(1.56)  LDD0629  [1]
 LDCM0313  AC50 HCT 116 C1574(1.23)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C1574(0.72)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C1574(1.07)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C1574(1.08)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C1574(1.19)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C1574(1.17)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C1574(1.65)  LDD0636  [1]
 LDCM0320  AC57 HCT 116 C1574(1.61)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C1574(1.42)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C1574(1.55)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C1574(1.36)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C1574(1.49)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C1574(1.37)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C1574(1.60)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C1574(1.47)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C1574(1.75)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C1574(1.76)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C1574(1.67)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C1574(1.68)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C1574(1.17)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C1574(1.41)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C1574(1.21)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C1574(1.50)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C1574(1.42)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C1574(1.47)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C1574(1.53)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C1574(1.63)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C1574(2.06)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C1574(1.27)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C1574(1.39)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C1574(1.28)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C1574(1.51)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C1574(1.29)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C1574(1.30)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C1574(1.53)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C1574(2.09)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C1574(1.43)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C1574(1.42)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C1574(1.22)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C1574(1.06)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C1574(0.93)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C1574(1.07)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C1574(1.22)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C1574(0.85)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C1574(1.42)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C1574(1.29)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C1574(1.16)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C1574(1.08)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C1574(0.91)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C1574(1.24)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C1574(1.34)  LDD0681  [1]
 LDCM0248  AKOS034007472 HCT 116 C1574(1.15)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C1574(1.40)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C1574(2.09)  LDD0592  [1]
 LDCM0369  CL100 HCT 116 C1574(1.47)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C1574(1.46)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C1574(1.20)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C1574(1.14)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C1574(1.31)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C1574(1.21)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C1574(1.50)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C1574(1.68)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C1574(1.45)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C1574(1.13)  LDD0695  [1]
 LDCM0380  CL110 HCT 116 C1574(1.43)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C1574(1.22)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C1574(1.05)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C1574(1.58)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C1574(1.32)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C1574(1.20)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C1574(1.33)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C1574(1.32)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C1574(1.08)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C1574(1.16)  LDD0706  [1]
 LDCM0391  CL120 HCT 116 C1574(1.03)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C1574(1.11)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C1574(1.34)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C1574(1.19)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C1574(1.28)  LDD0712  [1]
 LDCM0396  CL125 HCT 116 C1574(1.14)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C1574(1.39)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C1574(1.13)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C1574(1.49)  LDD0716  [1]
 LDCM0420  CL31 HCT 116 C1574(1.35)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C1574(1.48)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C1574(1.49)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C1574(1.81)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C1574(1.50)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C1574(1.63)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C1574(1.63)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C1574(1.64)  LDD0745  [1]
 LDCM0430  CL40 HCT 116 C1574(1.17)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C1574(1.88)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C1574(1.64)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C1574(2.18)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C1574(1.30)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C1574(1.85)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C1574(0.96)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C1574(0.94)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C1574(0.96)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C1574(1.13)  LDD0756  [1]
 LDCM0441  CL50 HCT 116 C1574(1.02)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C1574(0.86)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C1574(0.81)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C1574(0.95)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C1574(0.87)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C1574(0.93)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C1574(1.39)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C1574(0.86)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C1574(0.93)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C1574(1.06)  LDD0767  [1]
 LDCM0452  CL60 HCT 116 C1574(0.97)  LDD0769  [1]
 LDCM0469  CL76 HCT 116 C1574(1.13)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C1574(1.02)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C1574(0.98)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C1574(1.37)  LDD0789  [1]
 LDCM0474  CL80 HCT 116 C1574(1.01)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C1574(1.23)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C1574(1.58)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C1574(1.41)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C1574(1.90)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C1574(1.00)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C1574(0.99)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C1574(1.26)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C1574(1.38)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C1574(2.17)  LDD0800  [1]
 LDCM0485  CL90 HCT 116 C1574(1.01)  LDD0802  [1]
 LDCM0486  CL91 HCT 116 C1574(1.14)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C1574(1.62)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C1574(1.25)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C1574(1.52)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C1574(1.37)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C1574(1.32)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C1574(1.32)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C1574(1.65)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C1574(1.61)  LDD0811  [1]
 LDCM0427  Fragment51 HCT 116 C1574(2.00)  LDD0744  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.