Details of the Target

General Information of Target

Target ID LDTP06306
Target Name Periostin (POSTN)
Gene Name POSTN
Gene ID 10631
Synonyms
OSF2; Periostin; PN; Osteoblast-specific factor 2; OSF-2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI
TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
Target Type
Literature-reported
Target Bioclass
Other
Subcellular location
Golgi apparatus
Function
Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.
TTD ID
T29187
Uniprot ID
Q15063
DrugMap ID
TT8ALTZ
Ensemble ID
ENST00000379742.4
HGNC ID
HGNC:16953

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 SNV: p.K53I .
AGS SNV: p.T785A .
HCC15 SNV: p.W531C .
HCC1806 SNV: p.T256A .
HEC1 SNV: p.I562N .
JURKAT Insertion: p.L521FfsTer19 .
LNCaP clone FGC SNV: p.H725Y .
LS123 SNV: p.C80F .
MOLT4 SNV: p.R657C IA-alkyne    Probe Info 
NCIH2172 SNV: p.E469D .
NCIH2286 SNV: p.P698H .
NUGC3 SNV: p.D811Y .
RKO SNV: p.S312P .
SHP77 SNV: p.Q836R .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C44(0.95)  LDD0531  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0167  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C44(0.95)  LDD0531  [1]
 LDCM0215  AC10 HEK-293T C80(1.23)  LDD0813  [1]
 LDCM0216  AC100 HCT 116 C80(0.94)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C80(1.05)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C80(0.81)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C80(0.98)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C80(1.08)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C80(1.17)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C80(1.03)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C80(1.19)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C80(1.00)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C80(0.96)  LDD0542  [1]
 LDCM0226  AC11 HEK-293T C80(0.83)  LDD0824  [1]
 LDCM0227  AC110 HCT 116 C80(0.96)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C80(1.08)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C80(0.99)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C80(1.23)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C80(0.83)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C80(0.88)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C80(0.99)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C80(0.92)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C80(0.71)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C80(0.81)  LDD0553  [1]
 LDCM0237  AC12 HEK-293T C80(0.95)  LDD0835  [1]
 LDCM0238  AC120 HCT 116 C80(0.74)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C80(0.80)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C80(0.89)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C80(0.95)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C80(1.12)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C80(0.80)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C80(0.94)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C80(0.82)  LDD0562  [1]
 LDCM0246  AC128 HCT 116 C80(0.73)  LDD0563  [1]
 LDCM0247  AC129 HCT 116 C80(0.81)  LDD0564  [1]
 LDCM0249  AC130 HCT 116 C80(1.07)  LDD0566  [1]
 LDCM0250  AC131 HCT 116 C80(0.97)  LDD0567  [1]
 LDCM0251  AC132 HCT 116 C80(0.88)  LDD0568  [1]
 LDCM0252  AC133 HCT 116 C80(0.97)  LDD0569  [1]
 LDCM0253  AC134 HCT 116 C80(1.21)  LDD0570  [1]
 LDCM0254  AC135 HCT 116 C80(0.96)  LDD0571  [1]
 LDCM0255  AC136 HCT 116 C80(1.08)  LDD0572  [1]
 LDCM0256  AC137 HCT 116 C80(1.06)  LDD0573  [1]
 LDCM0257  AC138 HCT 116 C80(1.08)  LDD0574  [1]
 LDCM0258  AC139 HCT 116 C80(1.35)  LDD0575  [1]
 LDCM0259  AC14 HEK-293T C80(1.20)  LDD0857  [1]
 LDCM0260  AC140 HCT 116 C80(0.96)  LDD0577  [1]
 LDCM0261  AC141 HCT 116 C80(1.16)  LDD0578  [1]
 LDCM0262  AC142 HCT 116 C80(1.03)  LDD0579  [1]
 LDCM0263  AC143 HCT 116 C44(0.85)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C44(1.01)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C44(0.94)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C44(1.14)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C44(0.95)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C44(1.20)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C44(1.26)  LDD0586  [1]
 LDCM0270  AC15 HEK-293T C80(1.36)  LDD0868  [1]
 LDCM0271  AC150 HCT 116 C44(1.02)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C44(0.99)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C44(1.10)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C44(1.54)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C44(0.91)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C44(1.10)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C44(1.24)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C44(1.16)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C44(0.91)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C44(0.89)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C44(1.07)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C44(1.17)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C44(0.51)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C44(0.67)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C44(0.72)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C44(0.67)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C44(0.91)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C80(0.98)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C80(0.99)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C80(1.04)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C80(1.17)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C80(1.35)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C44(1.08)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C80(1.42)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C80(1.05)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C80(1.26)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C80(1.25)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C80(0.88)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C44(1.01); C80(1.15)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C80(0.96); C44(1.09)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C80(0.91); C44(1.04)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C44(0.87); C80(1.07)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C44(1.13); C80(1.15)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C44(1.07)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C44(0.53); C80(1.23)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C80(1.04); C44(1.08)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C80(1.23); C44(1.37)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C80(1.15); C44(1.34)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C44(0.60); C80(1.10)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C80(1.02); C44(1.27)  LDD0624  [1]
 LDCM0308  AC46 HEK-293T C80(0.99)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C80(1.25)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C80(1.16)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C80(1.46)  LDD0909  [1]
 LDCM0312  AC5 HCT 116 C44(0.94)  LDD0629  [1]
 LDCM0313  AC50 HEK-293T C80(1.23)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C80(1.36)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C80(1.40)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C80(1.10)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C80(1.47)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C80(1.50)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C80(1.15)  LDD0917  [1]
 LDCM0320  AC57 HCT 116 C44(1.28)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C44(1.05)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C44(0.90)  LDD0639  [1]
 LDCM0323  AC6 HEK-293T C80(0.88)  LDD0921  [1]
 LDCM0324  AC60 HCT 116 C44(0.95)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C44(1.30)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C44(0.97)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C44(0.93)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C44(1.17)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C44(2.04)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C44(1.93)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C44(1.47)  LDD0648  [1]
 LDCM0332  AC68 HEK-293T C80(1.26)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C80(1.36)  LDD0931  [1]
 LDCM0334  AC7 HEK-293T C80(1.19)  LDD0932  [1]
 LDCM0335  AC70 HEK-293T C80(1.39)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C80(1.37)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C80(1.33)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C80(1.39)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C80(1.51)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C80(1.24)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C80(1.01)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C80(1.53)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C80(1.31)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C80(1.25)  LDD0942  [1]
 LDCM0345  AC8 HEK-293T C80(1.13)  LDD0943  [1]
 LDCM0346  AC80 HEK-293T C80(1.22)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C80(1.42)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C80(1.75)  LDD0946  [1]
 LDCM0349  AC83 HCT 116 C80(1.56)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C80(1.80)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C80(1.82)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C80(1.87)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C80(1.59)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C80(1.70)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C80(1.69)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C80(1.40)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C80(1.42)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C80(1.61)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C80(1.59)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C80(1.80)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C80(1.66)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C80(1.43)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C80(1.73)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C80(1.17)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C80(0.92)  LDD0683  [1]
 LDCM0248  AKOS034007472 HEK-293T C80(1.05)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C80(1.33)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C80(1.23)  LDD0873  [1]
 LDCM0367  CL1 HCT 116 C44(1.16)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C44(1.15)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C44(1.00)  LDD0686  [1]
 LDCM0370  CL101 HEK-293T C80(1.10)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C80(1.81)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C80(1.55)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C80(1.49)  LDD0971  [1]
 LDCM0374  CL105 HCT 116 C44(0.77)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C44(0.80)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C44(0.84)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C44(1.06)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C44(0.93)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C44(1.23)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C44(0.86)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C44(0.92)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C80(1.14)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C80(1.19)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C80(1.16)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C80(1.14)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C80(1.09)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C80(1.07); C44(1.60)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C80(1.14); C44(1.48)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C44(1.02); C80(1.09)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C44(1.27)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C80(1.14); C44(1.46)  LDD0708  [1]
 LDCM0392  CL121 HEK-293T C80(1.29)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C80(1.24)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C80(1.41)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C80(1.19)  LDD0993  [1]
 LDCM0396  CL125 HCT 116 C44(1.28)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C44(1.00)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C44(1.02)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C44(1.19)  LDD0716  [1]
 LDCM0400  CL13 HCT 116 C44(1.26)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C44(1.30)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C44(1.06)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C44(0.85)  LDD0720  [1]
 LDCM0404  CL17 HEK-293T C80(0.72)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C80(0.80)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C80(0.89)  LDD1004  [1]
 LDCM0407  CL2 HCT 116 C44(0.78)  LDD0724  [1]
 LDCM0408  CL20 HEK-293T C80(0.88)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C80(0.65)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C80(0.85)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C80(0.84)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C80(0.66)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C80(0.69)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C80(0.92)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C80(0.80)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C80(0.74)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C80(0.81)  LDD1015  [1]
 LDCM0418  CL3 HCT 116 C44(0.94)  LDD0735  [1]
 LDCM0419  CL30 HEK-293T C80(0.96)  LDD1017  [1]
 LDCM0420  CL31 PaTu 8988t C80(0.88)  LDD1299  [1]
 LDCM0421  CL32 HCT 116 C44(0.84)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C44(0.58)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C44(0.96)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C44(0.92)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C44(0.89)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C44(1.05)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C44(0.79)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C44(1.29)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C44(0.76)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C44(0.88)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C44(1.19)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C44(1.03)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C44(1.29)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C44(1.52)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C80(1.23)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C80(1.76)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C80(1.51)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C80(1.66)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C44(1.39)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C80(1.54)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C80(2.27)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C80(1.89)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C80(1.47)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C80(1.43)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C80(1.62)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C80(1.70)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C80(2.73)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C80(2.35)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C80(1.95)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C44(1.30)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C80(2.22)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C80(0.50)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C80(0.98)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C80(0.94)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C80(1.27)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C80(1.05)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C80(1.18)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C80(1.07)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C80(0.83)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C80(1.13)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C44(1.26)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C80(0.97)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C80(0.84)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C80(1.00)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C80(1.10)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C80(1.09)  LDD0784  [1]
 LDCM0473  CL8 HCT 116 C44(0.98)  LDD0790  [1]
 LDCM0480  CL86 HEK-293T C44(1.05)  LDD1683  [3]
 LDCM0484  CL9 HCT 116 C44(1.04)  LDD0801  [1]
 LDCM0486  CL91 HCT 116 C44(0.97)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C44(0.89)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C44(1.07)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C44(1.16)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C44(1.05)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C44(1.10)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C44(1.15)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C44(0.98)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C44(0.80)  LDD0811  [1]
 LDCM0468  Fragment33 HCT 116 C80(1.03)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C44(1.02)  LDD0744  [1]
 LDCM0022  KB02 A204 C60(0.78)  LDD2252  [4]
 LDCM0023  KB03 A204 C44(2.33)  LDD2669  [4]
 LDCM0024  KB05 MV4-11 C44(1.60)  LDD3338  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transforming growth factor-beta-induced protein ig-h3 (TGFBI) . Q15582

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840