Details of the Target

General Information of Target

Target ID LDTP04007
Target Name Huntingtin (HTT)
Gene Name HTT
Gene ID 3064
Synonyms
HD; IT15; Huntingtin; Huntington disease protein; HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQLPQPPPQAQP
LLPQPQPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSVRNSPE
FQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAP
RSLRAALWRFAELAHLVRPQKCRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMASFG
NFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLGLLV
PVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSAEQLVQVYEL
TLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTLTAVGGIGQLTAAKEESGGRSRSGSI
VELIAGGGSSCSPVLSRKQKGKVLLGEEEALEDDSESRSDVSSSALTASVKDEISGELAA
SSGVSTPGSAGHDIITEQPRSQHTLQADSVDLASCDLTSSATDGDEEDILSHSSSQVSAV
PSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDNQYLGLQIGQPQD
EDEEATGILPDEASEAFRNSSMALQQAHLLKNMSHCRQPSDSSVDKFVLRDEATEPGDQE
NKPCRIKGDIGQSTDDDSAPLVHCVRLLSASFLLTGGKNVLVPDRDVRVSVKALALSCVG
AAVALHPESFFSKLYKVPLDTTEYPEEQYVSDILNYIDHGDPQVRGATAILCGTLICSIL
SRSRFHVGDWMGTIRTLTGNTFSLADCIPLLRKTLKDESSVTCKLACTAVRNCVMSLCSS
SYSELGLQLIIDVLTLRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGL
LKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQGQADPVVAVARDQSSV
YLKLLMHETQPPSHFSVSTITRIYRGYNLLPSITDVTMENNLSRVIAAVSHELITSTTRA
LTFGCCEALCLLSTAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMATMILTLLSSAWFP
LDLSAHQDALILAGNLLAASAPKSLRSSWASEEEANPAATKQEEVWPALGDRALVPMVEQ
LFSHLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASVPLSP
KKGSEASAASRQSDTSGPVTTSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNST
EKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTLF
GTNLASQFDGLSSNPSKSQGRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQ
AEQENDTSGWFDVLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTT
CVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFF
LVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADA
GKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADIILPMLAK
QQMHIDSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPNTMASVSTVQLWISGILAIL
RVLISQSTEDIVLSRIQELSFSPYLISCTVINRLRDGDSTSTLEEHSEGKQIKNLPEETF
SRFLLQLVGILLEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAAT
RLFRSDGCGGSFYTLDSLNLRARSMITTHPALVLLWCQILLLVNHTDYRWWAEVQQTPKR
HSLSSTKLLSPQMSGEEEDSDLAAKLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLI
VNHIQDLISLSHEPPVQDFISAVHRNSAASGLFIQAIQSRCENLSTPTMLKKTLQCLEGI
HLSQSGAVLTLYVDRLLCTPFRVLARMVDILACRRVEMLLAANLQSSMAQLPMEELNRIQ
EYLQSSGLAQRHQRLYSLLDRFRLSTMQDSLSPSPPVSSHPLDGDGHVSLETVSPDKDWY
VHLVKSQCWTRSDSALLEGAELVNRIPAEDMNAFMMNSEFNLSLLAPCLSLGMSEISGGQ
KSALFEAAREVTLARVSGTVQQLPAVHHVFQPELPAEPAAYWSKLNDLFGDAALYQSLPT
LARALAQYLVVVSKLPSHLHLPPEKEKDIVKFVVATLEALSWHLIHEQIPLSLDLQAGLD
CCCLALQLPGLWSVVSSTEFVTHACSLIYCVHFILEAVAVQPGEQLLSPERRTNTPKAIS
EEEEEVDPNTQNPKYITAACEMVAEMVESLQSVLALGHKRNSGVPAFLTPLLRNIIISLA
RLPLVNSYTRVPPLVWKLGWSPKPGGDFGTAFPEIPVEFLQEKEVFKEFIYRINTLGWTS
RTQFEETWATLLGVLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPVAG
NPAVSCLEQQPRNKPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENIATHHLYQAWDPV
PSLSPATTGALISHEKLLLQINPERELGSMSYKLGQVSIHSVWLGNSITPLREEEWDEEE
EEEADAPAPSSPPTSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSSSARRTPAILISEV
VRSLLVVSDLFTERNQFELMYVTLTELRRVHPSEDEILAQYLVPATCKAAAVLGMDKAVA
EPVSRLLESTLRSSHLPSRVGALHGVLYVLECDLLDDTAKQLIPVISDYLLSNLKGIAHC
VNIHSQQHVLVMCATAFYLIENYPLDVGPEFSASIIQMCGVMLSGSEESTPSIIYHCALR
GLERLLLSEQLSRLDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKVSPGRTSD
PNPAAPDSESVIVAMERVSVLFDRIRKGFPCEARVVARILPQFLDDFFPPQDIMNKVIGE
FLSNQQPYPQFMATVVYKVFQTLHSTGQSSMVRDWVMLSLSNFTQRAPVAMATWSLSCFF
VSASTSPWVAAILPHVISRMGKLEQVDVNLFCLVATDFYRHQIEEELDRRAFQSVLEVVA
APGSPYHRLLTCLRNVHKVTTC
Target Type
Clinical trial
Target Bioclass
Transporter and channel
Family
Huntingtin family
Subcellular location
Cytoplasm; Cytoplasmic vesicle, autophagosome
Function [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function.; [Huntingtin, myristoylated N-terminal fragment]: Promotes the formation of autophagic vesicles.
TTD ID
T22496
Uniprot ID
P42858
DrugMap ID
TTUKLBM
Ensemble ID
ENST00000355072.11
HGNC ID
HGNC:4851
ChEMBL ID
CHEMBL5514

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 16 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
STPyne
 Probe Info  		K1431(6.25)  LDD0277  [2]
BTD
 Probe Info  		C278(1.19)  LDD2099  [3]
YY4-yne
 Probe Info  		2.36  LDD0400  [4]
AHL-Pu-1
 Probe Info  		C2971(2.24); C942(2.46)  LDD0169  [5]
Acrolein
 Probe Info  		C1152(0.00); C2013(0.00)  LDD0222  [6]
DBIA
 Probe Info  		C664(0.92)  LDD0078  [7]
IA-alkyne
 Probe Info  		C636(0.00); C942(0.00); C1152(0.00)  LDD0162  [8]
WYneN
 Probe Info  		N.A.  LDD0021  [9]
ENE
 Probe Info  		N.A.  LDD0006  [9]
IPM
 Probe Info  		C1441(0.00); C827(0.00); C2971(0.00); C1961(0.00)  LDD0005  [9]
TFBX
 Probe Info  		C1998(0.00); C2971(0.00); C942(0.00); C1961(0.00)  LDD0148  [10]
VSF
 Probe Info  		C1961(0.00); C2971(0.00)  LDD0007  [9]
Methacrolein
 Probe Info  		C636(0.00); C278(0.00)  LDD0218  [6]
AOyne
 Probe Info  		9.40  LDD0443  [11]
NAIA_5
 Probe Info  		C718(0.00); C1961(0.00); C202(0.00); C664(0.00)  LDD2223  [12]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C1889(0.66)  LDD2117  [3]
 LDCM0025  4SU-RNA DM93 C636(3.38); C1441(2.74)  LDD0170  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C2971(2.24); C942(2.46)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C103(1.57); C107(1.57); C202(0.99); C212(0.99)  LDD0531  [7]
 LDCM0215  AC10 HCT 116 C103(1.40); C107(1.40); C202(0.78); C212(0.78)  LDD0532  [7]
 LDCM0216  AC100 HCT 116 C103(0.44); C107(0.44)  LDD0533  [7]
 LDCM0217  AC101 HCT 116 C103(0.54); C107(0.54)  LDD0534  [7]
 LDCM0218  AC102 HCT 116 C103(0.45); C107(0.45)  LDD0535  [7]
 LDCM0219  AC103 HCT 116 C103(0.46); C107(0.46)  LDD0536  [7]
 LDCM0220  AC104 HCT 116 C103(0.49); C107(0.49)  LDD0537  [7]
 LDCM0221  AC105 HCT 116 C103(0.59); C107(0.59)  LDD0538  [7]
 LDCM0222  AC106 HCT 116 C103(0.49); C107(0.49)  LDD0539  [7]
 LDCM0223  AC107 HCT 116 C103(0.75); C107(0.81)  LDD0540  [7]
 LDCM0224  AC108 HCT 116 C103(0.35); C107(0.37)  LDD0541  [7]
 LDCM0225  AC109 HCT 116 C103(0.47); C107(0.37)  LDD0542  [7]
 LDCM0226  AC11 HCT 116 C103(1.24); C107(1.24); C202(0.77); C212(0.77)  LDD0543  [7]
 LDCM0227  AC110 HCT 116 C103(0.55); C107(0.50)  LDD0544  [7]
 LDCM0228  AC111 HCT 116 C103(0.46); C107(0.66)  LDD0545  [7]
 LDCM0229  AC112 HCT 116 C103(0.58); C107(0.56)  LDD0546  [7]
 LDCM0230  AC113 HEK-293T C1441(0.97); C664(0.97); C103(0.74); C107(0.69)  LDD0828  [7]
 LDCM0231  AC114 HEK-293T C1441(1.03); C664(0.92); C103(0.86); C107(0.94)  LDD0829  [7]
 LDCM0232  AC115 HEK-293T C1441(1.03); C664(1.22); C103(1.05); C107(1.20)  LDD0830  [7]
 LDCM0233  AC116 HEK-293T C1441(1.08); C664(1.09); C103(0.86); C107(0.88)  LDD0831  [7]
 LDCM0234  AC117 HEK-293T C1441(1.04); C664(1.41); C103(0.83); C107(0.94)  LDD0832  [7]
 LDCM0235  AC118 HEK-293T C1441(1.14); C664(1.06); C103(0.99); C107(1.21)  LDD0833  [7]
 LDCM0236  AC119 HEK-293T C1441(1.08); C664(1.24); C103(0.75); C107(0.69)  LDD0834  [7]
 LDCM0237  AC12 HCT 116 C103(1.06); C107(1.06); C202(0.69); C212(0.69)  LDD0554  [7]
 LDCM0238  AC120 HEK-293T C1441(1.08); C664(1.05); C103(1.96); C107(2.99)  LDD0836  [7]
 LDCM0239  AC121 HEK-293T C1441(1.12); C664(1.51); C103(0.74); C107(0.78)  LDD0837  [7]
 LDCM0240  AC122 HEK-293T C1441(1.16); C664(1.60); C103(0.78); C107(0.84)  LDD0838  [7]
 LDCM0241  AC123 HEK-293T C1441(1.13); C664(1.41); C103(0.68); C107(0.61)  LDD0839  [7]
 LDCM0242  AC124 HEK-293T C1441(1.05); C664(1.43); C103(0.77); C107(0.73)  LDD0840  [7]
 LDCM0243  AC125 HEK-293T C1441(1.28); C664(1.61); C103(0.68); C107(0.76)  LDD0841  [7]
 LDCM0244  AC126 HEK-293T C1441(1.42); C664(2.68); C103(0.71); C107(0.76)  LDD0842  [7]
 LDCM0245  AC127 HEK-293T C1441(1.49); C664(1.46); C103(0.79); C107(0.82)  LDD0843  [7]
 LDCM0246  AC128 HCT 116 C202(0.93); C212(0.93)  LDD0563  [7]
 LDCM0247  AC129 HCT 116 C202(0.92); C212(0.92)  LDD0564  [7]
 LDCM0249  AC130 HCT 116 C202(1.52); C212(1.52)  LDD0566  [7]
 LDCM0250  AC131 HCT 116 C202(1.18); C212(1.18)  LDD0567  [7]
 LDCM0251  AC132 HCT 116 C202(0.84); C212(0.84)  LDD0568  [7]
 LDCM0252  AC133 HCT 116 C202(0.95); C212(0.95)  LDD0569  [7]
 LDCM0253  AC134 HCT 116 C202(0.73); C212(0.73)  LDD0570  [7]
 LDCM0254  AC135 HCT 116 C202(0.77); C212(0.77)  LDD0571  [7]
 LDCM0255  AC136 HCT 116 C202(0.82); C212(0.82)  LDD0572  [7]
 LDCM0256  AC137 HCT 116 C202(0.65); C212(0.65)  LDD0573  [7]
 LDCM0257  AC138 HCT 116 C202(0.81); C212(0.81)  LDD0574  [7]
 LDCM0258  AC139 HCT 116 C202(0.83); C212(0.83)  LDD0575  [7]
 LDCM0259  AC14 HCT 116 C103(1.42); C107(1.42); C202(0.70); C212(0.70)  LDD0576  [7]
 LDCM0260  AC140 HCT 116 C202(1.19); C212(1.19)  LDD0577  [7]
 LDCM0261  AC141 HCT 116 C202(0.90); C212(0.90)  LDD0578  [7]
 LDCM0262  AC142 HCT 116 C202(0.71); C212(0.71)  LDD0579  [7]
 LDCM0263  AC143 HCT 116 C103(0.56); C107(0.56)  LDD0580  [7]
 LDCM0264  AC144 HCT 116 C103(0.82); C107(0.82)  LDD0581  [7]
 LDCM0265  AC145 HCT 116 C103(1.07); C107(1.07)  LDD0582  [7]
 LDCM0266  AC146 HCT 116 C103(1.01); C107(1.01)  LDD0583  [7]
 LDCM0267  AC147 HCT 116 C103(0.62); C107(0.62)  LDD0584  [7]
 LDCM0268  AC148 HCT 116 C103(1.19); C107(1.19)  LDD0585  [7]
 LDCM0269  AC149 HCT 116 C103(1.18); C107(1.18)  LDD0586  [7]
 LDCM0270  AC15 HCT 116 C202(0.74); C212(0.74); C103(1.09); C107(1.09)  LDD0587  [7]
 LDCM0271  AC150 HCT 116 C103(0.90); C107(0.90)  LDD0588  [7]
 LDCM0272  AC151 HCT 116 C103(0.75); C107(0.75)  LDD0589  [7]
 LDCM0273  AC152 HCT 116 C103(1.83); C107(1.83)  LDD0590  [7]
 LDCM0274  AC153 HCT 116 C103(0.80); C107(0.80)  LDD0591  [7]
 LDCM0621  AC154 HCT 116 C103(0.78); C107(0.78)  LDD2158  [7]
 LDCM0622  AC155 HCT 116 C103(0.93); C107(0.93)  LDD2159  [7]
 LDCM0623  AC156 HCT 116 C103(0.95); C107(0.95)  LDD2160  [7]
 LDCM0624  AC157 HCT 116 C103(0.63); C107(0.63)  LDD2161  [7]
 LDCM0276  AC17 HCT 116 C103(0.79); C107(0.79); C2013(0.93)  LDD0593  [7]
 LDCM0277  AC18 HCT 116 C2013(0.73); C103(0.96); C107(0.96)  LDD0594  [7]
 LDCM0278  AC19 HCT 116 C2013(0.75); C103(0.92); C107(0.92)  LDD0595  [7]
 LDCM0279  AC2 HCT 116 C202(1.13); C212(1.13); C103(1.67); C107(1.67)  LDD0596  [7]
 LDCM0280  AC20 HCT 116 C103(0.85); C107(0.85); C2013(0.91)  LDD0597  [7]
 LDCM0281  AC21 HCT 116 C2013(0.79); C103(0.84); C107(0.84)  LDD0598  [7]
 LDCM0282  AC22 HCT 116 C2013(0.87); C103(0.94); C107(0.94)  LDD0599  [7]
 LDCM0283  AC23 HCT 116 C2013(0.87); C103(0.97); C107(0.97)  LDD0600  [7]
 LDCM0284  AC24 HCT 116 C2013(0.97); C103(1.00); C107(1.00)  LDD0601  [7]
 LDCM0285  AC25 HCT 116 C2013(0.69); C103(1.04); C107(1.04)  LDD0602  [7]
 LDCM0286  AC26 HCT 116 C2013(0.64); C103(0.83); C107(0.83)  LDD0603  [7]
 LDCM0287  AC27 HCT 116 C2013(0.62); C103(1.06); C107(1.06)  LDD0604  [7]
 LDCM0288  AC28 HCT 116 C2013(0.61); C103(0.96); C107(0.96)  LDD0605  [7]
 LDCM0289  AC29 HCT 116 C2013(0.61); C103(0.88); C107(0.88)  LDD0606  [7]
 LDCM0290  AC3 HCT 116 C202(1.07); C212(1.07); C103(2.87); C107(2.87)  LDD0607  [7]
 LDCM0291  AC30 HCT 116 C2013(0.59); C103(0.95); C107(0.95)  LDD0608  [7]
 LDCM0292  AC31 HCT 116 C2013(0.52); C103(0.88); C107(0.88)  LDD0609  [7]
 LDCM0293  AC32 HCT 116 C2013(0.57); C103(0.97); C107(0.97)  LDD0610  [7]
 LDCM0294  AC33 HCT 116 C2013(0.50); C103(0.98); C107(0.98)  LDD0611  [7]
 LDCM0295  AC34 HCT 116 C2013(0.58); C103(1.07); C107(1.07)  LDD0612  [7]
 LDCM0296  AC35 HCT 116 C103(0.95); C107(0.95); C2013(1.02)  LDD0613  [7]
 LDCM0297  AC36 HCT 116 C2013(0.88); C103(1.18); C107(1.18)  LDD0614  [7]
 LDCM0298  AC37 HCT 116 C2013(0.90); C103(1.17); C107(1.17)  LDD0615  [7]
 LDCM0299  AC38 HCT 116 C2013(0.89); C103(0.99); C107(0.99)  LDD0616  [7]
 LDCM0300  AC39 HCT 116 C2013(1.03); C103(1.04); C107(1.04)  LDD0617  [7]
 LDCM0301  AC4 HCT 116 C202(1.08); C212(1.08); C103(2.98); C107(2.98)  LDD0618  [7]
 LDCM0302  AC40 HCT 116 C103(0.83); C107(0.83); C2013(0.94)  LDD0619  [7]
 LDCM0303  AC41 HCT 116 C103(0.72); C107(0.72); C2013(0.87)  LDD0620  [7]
 LDCM0304  AC42 HCT 116 C2013(1.09); C103(1.43); C107(1.43)  LDD0621  [7]
 LDCM0305  AC43 HCT 116 C103(0.86); C107(0.86); C2013(0.90)  LDD0622  [7]
 LDCM0306  AC44 HCT 116 C2013(0.89); C103(1.59); C107(1.59)  LDD0623  [7]
 LDCM0307  AC45 HCT 116 C2013(1.02); C103(1.44); C107(1.44)  LDD0624  [7]
 LDCM0308  AC46 HCT 116 C2013(0.92)  LDD0625  [7]
 LDCM0309  AC47 HCT 116 C2013(1.01)  LDD0626  [7]
 LDCM0310  AC48 HCT 116 C2013(1.02)  LDD0627  [7]
 LDCM0311  AC49 HCT 116 C2013(1.15)  LDD0628  [7]
 LDCM0312  AC5 HCT 116 C202(0.94); C212(0.94); C103(3.97); C107(3.97)  LDD0629  [7]
 LDCM0313  AC50 HCT 116 C2013(1.06)  LDD0630  [7]
 LDCM0314  AC51 HCT 116 C2013(1.06)  LDD0631  [7]
 LDCM0315  AC52 HCT 116 C2013(0.99)  LDD0632  [7]
 LDCM0316  AC53 HCT 116 C2013(0.91)  LDD0633  [7]
 LDCM0317  AC54 HCT 116 C2013(1.07)  LDD0634  [7]
 LDCM0318  AC55 HCT 116 C2013(1.04)  LDD0635  [7]
 LDCM0319  AC56 HCT 116 C2013(1.37)  LDD0636  [7]
 LDCM0320  AC57 HCT 116 C103(0.83); C107(0.83); C2013(0.91)  LDD0637  [7]
 LDCM0321  AC58 HCT 116 C2013(0.88); C103(0.96); C107(0.96)  LDD0638  [7]
 LDCM0322  AC59 HCT 116 C103(0.97); C107(0.97); C2013(1.00)  LDD0639  [7]
 LDCM0323  AC6 HCT 116 C103(0.88); C107(0.88); C202(1.05); C212(1.05)  LDD0640  [7]
 LDCM0324  AC60 HCT 116 C2013(0.87); C103(1.23); C107(1.23)  LDD0641  [7]
 LDCM0325  AC61 HCT 116 C2013(0.78); C103(0.86); C107(0.86)  LDD0642  [7]
 LDCM0326  AC62 HCT 116 C103(0.97); C107(0.97); C2013(1.02)  LDD0643  [7]
 LDCM0327  AC63 HCT 116 C2013(0.82); C103(0.98); C107(0.98)  LDD0644  [7]
 LDCM0328  AC64 HCT 116 C2013(1.05); C103(1.09); C107(1.09)  LDD0645  [7]
 LDCM0329  AC65 HCT 116 C2013(1.36); C103(1.40); C107(1.40)  LDD0646  [7]
 LDCM0330  AC66 HCT 116 C103(1.23); C107(1.23); C2013(1.30)  LDD0647  [7]
 LDCM0331  AC67 HCT 116 C103(1.08); C107(1.08); C2013(1.28)  LDD0648  [7]
 LDCM0332  AC68 HCT 116 C202(0.68); C212(0.68); C103(1.10); C107(1.10)  LDD0649  [7]
 LDCM0333  AC69 HCT 116 C202(0.79); C212(0.79); C103(1.04); C107(1.04)  LDD0650  [7]
 LDCM0334  AC7 HCT 116 C202(0.97); C212(0.97); C103(1.19); C107(1.19)  LDD0651  [7]
 LDCM0335  AC70 HCT 116 C202(0.73); C212(0.73); C103(1.35); C107(1.35)  LDD0652  [7]
 LDCM0336  AC71 HCT 116 C103(0.94); C107(0.94); C202(0.97); C212(0.97)  LDD0653  [7]
 LDCM0337  AC72 HCT 116 C202(0.82); C212(0.82); C103(0.91); C107(0.91)  LDD0654  [7]
 LDCM0338  AC73 HCT 116 C202(1.24); C212(1.24); C103(1.41); C107(1.41)  LDD0655  [7]
 LDCM0339  AC74 HCT 116 C202(0.90); C212(0.90); C103(1.35); C107(1.35)  LDD0656  [7]
 LDCM0340  AC75 HCT 116 C202(1.17); C212(1.17); C103(1.95); C107(1.95)  LDD0657  [7]
 LDCM0341  AC76 HCT 116 C202(0.90); C212(0.90); C103(1.37); C107(1.37)  LDD0658  [7]
 LDCM0342  AC77 HCT 116 C202(1.26); C212(1.26); C103(1.31); C107(1.31)  LDD0659  [7]
 LDCM0343  AC78 HCT 116 C202(0.87); C212(0.87); C103(0.94); C107(0.94)  LDD0660  [7]
 LDCM0344  AC79 HCT 116 C202(0.92); C212(0.92); C103(0.94); C107(0.94)  LDD0661  [7]
 LDCM0345  AC8 HCT 116 C202(0.87); C212(0.87); C103(1.14); C107(1.14)  LDD0662  [7]
 LDCM0346  AC80 HCT 116 C202(0.93); C212(0.93); C103(1.08); C107(1.08)  LDD0663  [7]
 LDCM0347  AC81 HCT 116 C202(0.50); C212(0.50); C103(0.79); C107(0.79)  LDD0664  [7]
 LDCM0348  AC82 HCT 116 C202(1.11); C212(1.11); C103(1.67); C107(1.67)  LDD0665  [7]
 LDCM0349  AC83 HCT 116 C103(1.32); C107(1.32)  LDD0666  [7]
 LDCM0350  AC84 HCT 116 C103(1.30); C107(1.30)  LDD0667  [7]
 LDCM0351  AC85 HCT 116 C103(1.07); C107(1.07)  LDD0668  [7]
 LDCM0352  AC86 HCT 116 C103(1.17); C107(1.17)  LDD0669  [7]
 LDCM0353  AC87 HCT 116 C103(0.98); C107(0.98)  LDD0670  [7]
 LDCM0354  AC88 HCT 116 C103(1.32); C107(1.32)  LDD0671  [7]
 LDCM0355  AC89 HCT 116 C103(1.44); C107(1.44)  LDD0672  [7]
 LDCM0357  AC90 HCT 116 C103(1.88); C107(1.88)  LDD0674  [7]
 LDCM0358  AC91 HCT 116 C103(1.43); C107(1.43)  LDD0675  [7]
 LDCM0359  AC92 HCT 116 C103(1.09); C107(1.09)  LDD0676  [7]
 LDCM0360  AC93 HCT 116 C103(1.10); C107(1.10)  LDD0677  [7]
 LDCM0361  AC94 HCT 116 C103(0.95); C107(0.95)  LDD0678  [7]
 LDCM0362  AC95 HCT 116 C103(1.01); C107(1.01)  LDD0679  [7]
 LDCM0363  AC96 HCT 116 C103(1.14); C107(1.14)  LDD0680  [7]
 LDCM0364  AC97 HCT 116 C103(1.16); C107(1.16)  LDD0681  [7]
 LDCM0365  AC98 HCT 116 C103(0.78); C107(0.78)  LDD0682  [7]
 LDCM0366  AC99 HCT 116 C103(0.50); C107(0.50)  LDD0683  [7]
 LDCM0248  AKOS034007472 HCT 116 C103(1.08); C107(1.08); C202(0.96); C212(0.96)  LDD0565  [7]
 LDCM0356  AKOS034007680 HCT 116 C202(0.78); C212(0.78); C103(1.35); C107(1.35)  LDD0673  [7]
 LDCM0275  AKOS034007705 HCT 116 C202(1.03); C212(1.03); C103(1.28); C107(1.28)  LDD0592  [7]
 LDCM0020  ARS-1620 HCC44 C664(0.92)  LDD0078  [7]
 LDCM0108  Chloroacetamide HeLa C1152(0.00); C2013(0.00)  LDD0222  [6]
 LDCM0632  CL-Sc Hep-G2 C664(1.90); C278(1.25); C1524(1.17); C942(0.24)  LDD2227  [12]
 LDCM0367  CL1 HCT 116 C2013(1.06)  LDD0684  [7]
 LDCM0368  CL10 HCT 116 C2013(0.95)  LDD0685  [7]
 LDCM0369  CL100 HCT 116 C202(1.14); C212(1.14); C103(1.77); C107(1.77)  LDD0686  [7]
 LDCM0370  CL101 HCT 116 C202(0.81); C212(0.81); C103(1.11); C107(1.11)  LDD0687  [7]
 LDCM0371  CL102 HCT 116 C202(0.78); C212(0.78); C103(1.13); C107(1.13)  LDD0688  [7]
 LDCM0372  CL103 HCT 116 C202(0.85); C212(0.85); C103(0.99); C107(0.99)  LDD0689  [7]
 LDCM0373  CL104 HCT 116 C202(0.96); C212(0.96); C103(1.13); C107(1.13)  LDD0690  [7]
 LDCM0374  CL105 HCT 116 C2013(0.79); C103(0.84); C107(0.84)  LDD0691  [7]
 LDCM0375  CL106 HCT 116 C2013(0.79); C103(0.90); C107(0.90)  LDD0692  [7]
 LDCM0376  CL107 HCT 116 C2013(0.90); C103(1.06); C107(1.06)  LDD0693  [7]
 LDCM0377  CL108 HCT 116 C2013(0.86); C103(1.28); C107(1.28)  LDD0694  [7]
 LDCM0378  CL109 HCT 116 C2013(0.81); C103(0.99); C107(0.99)  LDD0695  [7]
 LDCM0379  CL11 HCT 116 C2013(1.17)  LDD0696  [7]
 LDCM0380  CL110 HCT 116 C2013(0.73); C103(0.91); C107(0.91)  LDD0697  [7]
 LDCM0381  CL111 HCT 116 C2013(0.80); C103(0.87); C107(0.87)  LDD0698  [7]
 LDCM0382  CL112 HCT 116 C2013(0.63); C103(1.14); C107(1.14)  LDD0699  [7]
 LDCM0383  CL113 HCT 116 C2013(0.62); C103(0.86); C107(0.86)  LDD0700  [7]
 LDCM0384  CL114 HCT 116 C2013(0.58); C103(0.90); C107(0.90)  LDD0701  [7]
 LDCM0385  CL115 HCT 116 C2013(0.62); C103(0.92); C107(0.92)  LDD0702  [7]
 LDCM0386  CL116 HCT 116 C2013(0.68); C103(1.05); C107(1.05)  LDD0703  [7]
 LDCM0387  CL117 HCT 116 C2013(1.07); C103(1.24); C107(1.24)  LDD0704  [7]
 LDCM0388  CL118 HCT 116 C2013(0.95); C103(1.71); C107(1.71)  LDD0705  [7]
 LDCM0389  CL119 HCT 116 C2013(0.83); C103(0.94); C107(0.94)  LDD0706  [7]
 LDCM0390  CL12 HCT 116 C2013(1.04)  LDD0707  [7]
 LDCM0391  CL120 HCT 116 C103(0.74); C107(0.74); C2013(0.94)  LDD0708  [7]
 LDCM0392  CL121 HCT 116 C2013(0.85)  LDD0709  [7]
 LDCM0393  CL122 HCT 116 C2013(0.97)  LDD0710  [7]
 LDCM0394  CL123 HCT 116 C2013(0.94)  LDD0711  [7]
 LDCM0395  CL124 HCT 116 C2013(1.12)  LDD0712  [7]
 LDCM0396  CL125 HCT 116 C103(0.75); C107(0.75); C2013(1.07)  LDD0713  [7]
 LDCM0397  CL126 HCT 116 C2013(0.88); C103(0.95); C107(0.95)  LDD0714  [7]
 LDCM0398  CL127 HCT 116 C103(0.86); C107(0.86); C2013(0.90)  LDD0715  [7]
 LDCM0399  CL128 HCT 116 C2013(0.86); C103(1.05); C107(1.05)  LDD0716  [7]
 LDCM0400  CL13 HCT 116 C2013(1.05)  LDD0717  [7]
 LDCM0401  CL14 HCT 116 C2013(0.92)  LDD0718  [7]
 LDCM0402  CL15 HCT 116 C2013(0.99)  LDD0719  [7]
 LDCM0403  CL16 HEK-293T C1441(1.16); C664(1.01); C103(1.21); C107(0.92)  LDD1001  [7]
 LDCM0404  CL17 HEK-293T C1441(1.82); C664(1.77); C103(0.94); C107(0.88)  LDD1002  [7]
 LDCM0405  CL18 HEK-293T C1441(1.41); C664(1.11); C103(1.13); C107(1.09)  LDD1003  [7]
 LDCM0406  CL19 HEK-293T C1441(1.04); C664(1.08); C103(1.04); C107(1.00)  LDD1004  [7]
 LDCM0407  CL2 HCT 116 C2013(1.09)  LDD0724  [7]
 LDCM0408  CL20 HEK-293T C1441(0.97); C664(1.34); C103(0.93); C107(0.91)  LDD1006  [7]
 LDCM0409  CL21 HEK-293T C1441(5.75); C664(2.46); C103(1.04); C107(1.11)  LDD1007  [7]
 LDCM0410  CL22 HEK-293T C1441(1.02); C664(1.39); C103(1.08); C107(1.08)  LDD1008  [7]
 LDCM0411  CL23 HEK-293T C1441(1.08); C664(1.54); C103(1.03); C107(1.08)  LDD1009  [7]
 LDCM0412  CL24 HEK-293T C1441(1.22); C664(1.46); C103(1.15); C107(1.19)  LDD1010  [7]
 LDCM0413  CL25 HEK-293T C1441(1.71); C664(1.78); C103(1.05); C107(1.09)  LDD1011  [7]
 LDCM0414  CL26 HEK-293T C1441(1.15); C664(1.40); C103(1.05); C107(1.06)  LDD1012  [7]
 LDCM0415  CL27 HEK-293T C1441(1.39); C664(1.36); C103(1.02); C107(1.05)  LDD1013  [7]
 LDCM0416  CL28 HEK-293T C1441(1.29); C664(1.53); C103(1.08); C107(1.26)  LDD1014  [7]
 LDCM0417  CL29 HEK-293T C1441(0.96); C664(1.60); C103(1.08); C107(0.98)  LDD1015  [7]
 LDCM0418  CL3 HCT 116 C2013(0.90)  LDD0735  [7]
 LDCM0419  CL30 HEK-293T C1441(1.13); C664(2.03); C103(0.98); C107(1.04)  LDD1017  [7]
 LDCM0420  CL31 HEK-293T C1441(1.14); C664(0.97); C1808(0.93); C103(1.05)  LDD1018  [7]
 LDCM0421  CL32 HEK-293T C1441(1.40); C664(1.10); C1808(1.06); C103(0.98)  LDD1019  [7]
 LDCM0422  CL33 HEK-293T C1441(1.85); C664(2.84); C1808(1.30); C103(0.92)  LDD1020  [7]
 LDCM0423  CL34 HEK-293T C1441(1.40); C664(1.37); C1808(0.84); C103(0.85)  LDD1021  [7]
 LDCM0424  CL35 HEK-293T C1441(1.10); C664(1.26); C1808(1.03); C103(0.92)  LDD1022  [7]
 LDCM0425  CL36 HEK-293T C1441(1.80); C664(1.25); C1808(1.08); C103(0.88)  LDD1023  [7]
 LDCM0426  CL37 HEK-293T C1441(1.50); C664(1.30); C1808(1.19); C103(0.86)  LDD1024  [7]
 LDCM0428  CL39 HEK-293T C1441(1.68); C664(3.55); C1808(0.97); C103(0.76)  LDD1026  [7]
 LDCM0429  CL4 HCT 116 C2013(0.96)  LDD0746  [7]
 LDCM0430  CL40 HEK-293T C1441(1.33); C664(1.21); C1808(1.13); C103(0.93)  LDD1028  [7]
 LDCM0431  CL41 HEK-293T C1441(1.83); C664(2.92); C1808(1.09); C103(0.83)  LDD1029  [7]
 LDCM0432  CL42 HEK-293T C1441(1.54); C664(2.33); C1808(1.01); C103(0.89)  LDD1030  [7]
 LDCM0433  CL43 HEK-293T C1441(1.59); C664(2.20); C1808(0.89); C103(0.69)  LDD1031  [7]
 LDCM0434  CL44 HEK-293T C1441(1.16); C664(1.38); C1808(1.02); C103(0.88)  LDD1032  [7]
 LDCM0435  CL45 HEK-293T C1441(2.07); C664(3.13); C1808(1.04); C103(0.76)  LDD1033  [7]
 LDCM0436  CL46 HCT 116 C103(0.81); C107(0.81)  LDD0753  [7]
 LDCM0437  CL47 HCT 116 C103(0.86); C107(0.86)  LDD0754  [7]
 LDCM0438  CL48 HCT 116 C103(0.96); C107(0.96)  LDD0755  [7]
 LDCM0439  CL49 HCT 116 C103(0.76); C107(0.76)  LDD0756  [7]
 LDCM0440  CL5 HCT 116 C2013(1.04)  LDD0757  [7]
 LDCM0441  CL50 HCT 116 C103(0.86); C107(0.86)  LDD0758  [7]
 LDCM0442  CL51 HCT 116 C103(0.81); C107(0.81)  LDD0759  [7]
 LDCM0443  CL52 HCT 116 C103(0.92); C107(0.92)  LDD0760  [7]
 LDCM0444  CL53 HCT 116 C103(0.81); C107(0.81)  LDD0761  [7]
 LDCM0445  CL54 HCT 116 C103(0.86); C107(0.86)  LDD0762  [7]
 LDCM0446  CL55 HCT 116 C103(0.91); C107(0.91)  LDD0763  [7]
 LDCM0447  CL56 HCT 116 C103(0.80); C107(0.80)  LDD0764  [7]
 LDCM0448  CL57 HCT 116 C103(0.69); C107(0.69)  LDD0765  [7]
 LDCM0449  CL58 HCT 116 C103(1.03); C107(1.03)  LDD0766  [7]
 LDCM0450  CL59 HCT 116 C103(0.91); C107(0.91)  LDD0767  [7]
 LDCM0451  CL6 HCT 116 C2013(0.94)  LDD0768  [7]
 LDCM0452  CL60 HCT 116 C103(0.85); C107(0.85)  LDD0769  [7]
 LDCM0453  CL61 HCT 116 C103(0.84); C107(0.84)  LDD0770  [7]
 LDCM0454  CL62 HCT 116 C103(0.90); C107(0.90)  LDD0771  [7]
 LDCM0455  CL63 HCT 116 C103(0.78); C107(0.78)  LDD0772  [7]
 LDCM0456  CL64 HCT 116 C103(0.86); C107(0.86)  LDD0773  [7]
 LDCM0457  CL65 HCT 116 C103(0.80); C107(0.80)  LDD0774  [7]
 LDCM0458  CL66 HCT 116 C103(1.00); C107(1.00)  LDD0775  [7]
 LDCM0459  CL67 HCT 116 C103(0.86); C107(0.86)  LDD0776  [7]
 LDCM0460  CL68 HCT 116 C103(0.67); C107(0.67)  LDD0777  [7]
 LDCM0461  CL69 HCT 116 C103(0.91); C107(0.91)  LDD0778  [7]
 LDCM0462  CL7 HCT 116 C2013(1.16)  LDD0779  [7]
 LDCM0463  CL70 HCT 116 C103(1.05); C107(1.05)  LDD0780  [7]
 LDCM0464  CL71 HCT 116 C103(0.86); C107(0.86)  LDD0781  [7]
 LDCM0465  CL72 HCT 116 C103(1.06); C107(1.06)  LDD0782  [7]
 LDCM0466  CL73 HCT 116 C103(1.03); C107(1.03)  LDD0783  [7]
 LDCM0467  CL74 HCT 116 C103(0.73); C107(0.73)  LDD0784  [7]
 LDCM0469  CL76 HEK-293T C1441(1.03); C664(0.80); C1808(1.07); C103(1.20)  LDD1067  [7]
 LDCM0470  CL77 HEK-293T C1441(4.31); C664(1.17); C1808(1.00); C103(1.31)  LDD1068  [7]
 LDCM0471  CL78 HEK-293T C1441(1.28); C664(0.52); C1808(0.91); C103(1.25)  LDD1069  [7]
 LDCM0472  CL79 HEK-293T C1441(1.33); C664(0.76); C1808(1.05); C103(0.90)  LDD1070  [7]
 LDCM0473  CL8 HCT 116 C2013(1.07)  LDD0790  [7]
 LDCM0474  CL80 HEK-293T C1441(1.16); C664(0.82); C1808(1.11); C103(0.77)  LDD1072  [7]
 LDCM0475  CL81 HEK-293T C1441(1.47); C664(0.90); C1808(1.00); C103(1.09)  LDD1073  [7]
 LDCM0476  CL82 HEK-293T C1441(1.08); C664(1.05); C1808(1.01); C103(1.71)  LDD1074  [7]
 LDCM0477  CL83 HEK-293T C1441(1.32); C664(1.05); C1808(0.94); C103(1.29)  LDD1075  [7]
 LDCM0478  CL84 HEK-293T C1441(4.66); C664(0.82); C1808(1.23); C103(0.80)  LDD1076  [7]
 LDCM0479  CL85 HEK-293T C1441(1.24); C664(0.74); C1808(1.13); C103(0.93)  LDD1077  [7]
 LDCM0480  CL86 HEK-293T C1441(1.38); C664(0.77); C1808(1.13); C103(0.86)  LDD1078  [7]
 LDCM0481  CL87 HEK-293T C1441(1.44); C664(1.02); C1808(1.14); C103(0.92)  LDD1079  [7]
 LDCM0482  CL88 HEK-293T C1441(1.28); C664(0.93); C1808(1.32); C103(0.87)  LDD1080  [7]
 LDCM0483  CL89 HEK-293T C1441(1.54); C664(0.72); C1808(0.91); C103(0.97)  LDD1081  [7]
 LDCM0484  CL9 HCT 116 C2013(1.01)  LDD0801  [7]
 LDCM0485  CL90 HEK-293T C1441(2.66); C664(1.66); C1808(1.03); C103(0.61)  LDD1083  [7]
 LDCM0486  CL91 HCT 116 C103(1.22); C107(1.22); C202(1.02); C212(1.02)  LDD0803  [7]
 LDCM0487  CL92 HCT 116 C103(1.05); C107(1.05); C202(0.89); C212(0.89)  LDD0804  [7]
 LDCM0488  CL93 HCT 116 C103(1.02); C107(1.02); C202(1.08); C212(1.08)  LDD0805  [7]
 LDCM0489  CL94 HCT 116 C103(0.64); C107(0.64); C202(1.00); C212(1.00)  LDD0806  [7]
 LDCM0490  CL95 HCT 116 C103(1.02); C107(1.02); C202(0.91); C212(0.91)  LDD0807  [7]
 LDCM0491  CL96 HCT 116 C103(1.17); C107(1.17); C202(1.03); C212(1.03)  LDD0808  [7]
 LDCM0492  CL97 HCT 116 C103(1.78); C107(1.78); C202(1.15); C212(1.15)  LDD0809  [7]
 LDCM0493  CL98 HCT 116 C103(2.48); C107(2.48); C202(0.97); C212(0.97)  LDD0810  [7]
 LDCM0494  CL99 HCT 116 C103(2.66); C107(2.66); C202(1.04); C212(1.04)  LDD0811  [7]
 LDCM0495  E2913 HEK-293T C664(1.03); C278(1.03); C823(0.98); C2971(1.09)  LDD1698  [13]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C1998(2.04); C1889(1.46)  LDD1702  [3]
 LDCM0202  EV-93 T cell C1441(17.36)  LDD0514  [14]
 LDCM0625  F8 Ramos C1998(0.90); C2013(0.64); C942(1.22); C278(1.48)  LDD2187  [15]
 LDCM0572  Fragment10 Ramos C1998(1.66); C2013(0.59); C942(1.71); C278(0.72)  LDD2189  [15]
 LDCM0573  Fragment11 Ramos C1998(0.89); C2013(1.78); C942(1.15); C278(20.00)  LDD2190  [15]
 LDCM0574  Fragment12 Ramos C1998(0.82); C2013(0.47); C942(0.70); C278(0.46)  LDD2191  [15]
 LDCM0575  Fragment13 Ramos C1998(0.88); C2013(0.75); C942(0.79); C278(1.27)  LDD2192  [15]
 LDCM0576  Fragment14 Ramos C1998(0.43); C2013(0.65); C942(0.83); C278(0.94)  LDD2193  [15]
 LDCM0579  Fragment20 Ramos C1998(1.14); C2013(0.56); C942(0.83); C278(0.54)  LDD2194  [15]
 LDCM0580  Fragment21 Ramos C1998(0.88); C2013(0.78); C942(0.77); C278(0.52)  LDD2195  [15]
 LDCM0582  Fragment23 Ramos C1998(1.32); C2013(0.68); C942(0.68); C278(0.24)  LDD2196  [15]
 LDCM0578  Fragment27 Ramos C1998(0.81); C2013(0.77); C942(0.78); C278(0.83)  LDD2197  [15]
 LDCM0586  Fragment28 Ramos C1998(0.93); C2013(0.82); C942(1.12); C278(1.76)  LDD2198  [15]
 LDCM0588  Fragment30 Ramos C1998(1.25); C2013(1.15); C942(1.15); C278(1.22)  LDD2199  [15]
 LDCM0589  Fragment31 Ramos C1998(0.94); C2013(1.10); C942(0.69); C278(1.11)  LDD2200  [15]
 LDCM0590  Fragment32 Ramos C1998(0.88); C2013(0.47); C942(2.11); C278(0.70)  LDD2201  [15]
 LDCM0468  Fragment33 HCT 116 C103(0.86); C107(0.86)  LDD0785  [7]
 LDCM0596  Fragment38 Ramos C1998(0.73); C2013(0.72); C942(0.73); C278(1.24)  LDD2203  [15]
 LDCM0566  Fragment4 Ramos C1998(0.70); C2013(0.51); C942(1.22); C278(0.46)  LDD2184  [15]
 LDCM0427  Fragment51 HEK-293T C1441(1.29); C664(1.18); C1808(0.74); C103(0.86)  LDD1025  [7]
 LDCM0610  Fragment52 Ramos C1998(0.96); C2013(0.66); C942(0.92); C278(0.93)  LDD2204  [15]
 LDCM0614  Fragment56 Ramos C1998(1.04); C2013(0.87); C942(1.01); C278(1.49)  LDD2205  [15]
 LDCM0569  Fragment7 Ramos C1998(0.73); C2013(0.55); C942(0.70); C278(0.78)  LDD2186  [15]
 LDCM0571  Fragment9 Ramos C1998(1.43); C2013(0.60); C942(1.01); C278(0.59)  LDD2188  [15]
 LDCM0022  KB02 HCT 116 C823(2.42); C431(2.33); C664(2.11); C1998(1.46)  LDD0080  [7]
 LDCM0023  KB03 HCT 116 C823(2.95); C431(2.19); C664(1.29); C1998(1.85)  LDD0081  [7]
 LDCM0024  KB05 HCT 116 C823(4.11); C431(2.08); C664(2.00); C1998(1.57)  LDD0082  [7]
 LDCM0109  NEM HeLa N.A.  LDD0233  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C278(1.19)  LDD2099  [3]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C827(0.91)  LDD2118  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C2013(0.43)  LDD2127  [3]
 LDCM0154  YY4 T cell 2.36  LDD0400  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 198 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) 2-oxoacid dehydrogenase family P36957
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) CNPase family P09543
26S proteasome regulatory subunit 6A (PSMC3) AAA ATPase family P17980
Transitional endoplasmic reticulum ATPase (VCP) AAA ATPase family P55072
Vacuolar protein sorting-associated protein 4B (VPS4B) AAA ATPase family O75351
AFG3-like protein 2 (AFG3L2) AAA ATPase family; Peptidase M41 family Q9Y4W6
Alpha/beta hydrolase domain-containing protein 17C (ABHD17C) ABHD17 family Q6PCB6
Actin, cytoplasmic 1 (ACTB) Actin family P60709
Actin, cytoplasmic 2 (ACTG1) Actin family P63261
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) Adenylate kinase family Q9UIJ7
S-adenosylmethionine synthase isoform type-1 (MAT1A) AdoMet synthase family Q00266
Acylglycerol kinase, mitochondrial (AGK) AGK family Q53H12
Aldo-keto reductase family 1 member A1 (AKR1A1) Aldo/keto reductase family P14550
2-oxoglutarate dehydrogenase complex component E1 (OGDH) Alpha-ketoglutarate dehydrogenase family Q02218
Piwi-like protein 1 (PIWIL1) Argonaute family Q96J94
Creatine kinase M-type (CKM) ATP:guanido phosphotransferase family P06732
E3 ubiquitin-protein ligase BRE1A (RNF20) BRE1 family Q5VTR2
E3 ubiquitin-protein ligase BRE1B (RNF40) BRE1 family O75150
CCR4-NOT transcription complex subunit 7 (CNOT7) CAF1 family Q9UIV1
Prostaglandin-H2 D-isomerase (PTGDS) Lipocalin family P41222
Phosphatidate cytidylyltransferase 2 (CDS2) CDS family O95674
Protein arginine N-methyltransferase 2 (PRMT2) Protein arginine N-methyltransferase family P55345
Histone-lysine N-methyltransferase SETD2 (SETD2) Histone-lysine methyltransferase family Q9BYW2
Glutamine--tRNA ligase (QARS1) Class-I aminoacyl-tRNA synthetase family P47897
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) Class-I pyridine nucleotide-disulfide oxidoreductase family P09622
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) Complex I LYR family Q9Y6M9
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) Complex I NDUFA13 subunit family Q9P0J0
Normal mucosa of esophagus-specific gene 1 protein (NMES1) Complex I NDUFA4 subunit family Q9C002
NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial (NDUFA9) Complex I NDUFA9 subunit family Q16795
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) Complex I NDUFB10 subunit family O96000
NADH dehydrogenase iron-sulfur protein 5 (NDUFS5) Complex I NDUFS5 subunit family O43920
Amine oxidase [copper-containing] 3 (AOC3) Copper/topaquinone oxidase family Q16853
COP9 signalosome complex subunit 3 (COPS3) CSN3 family Q9UNS2
Cullin-3 (CUL3) Cullin family Q13618
Cullin-5 (CUL5) Cullin family Q93034
Peptidyl-prolyl cis-trans isomerase H (PPIH) Cyclophilin-type PPIase family O43447
Cystathionine beta-synthase (CBS) Cysteine synthase/cystathionine beta-synthase family P35520
Cytochrome c1, heme protein, mitochondrial (CYC1) Cytochrome c family P08574
Cytochrome c oxidase subunit 6A1, mitochondrial (COX6A1) Cytochrome c oxidase subunit 6A family P12074
Cytochrome c oxidase subunit 6C (COX6C) Cytochrome c oxidase subunit 6c family P09669
Cytochrome P450 3A5 (CYP3A5) Cytochrome P450 family P20815
Probable ATP-dependent RNA helicase DDX20 (DDX20) DEAD box helicase family Q9UHI6
Nucleolar RNA helicase 2 (DDX21) DEAD box helicase family Q9NR30
Probable ATP-dependent RNA helicase DDX41 (DDX41) DEAD box helicase family Q9UJV9
ATP-dependent RNA helicase DDX39A (DDX39A) DEAD box helicase family O00148
Palmitoyltransferase ZDHHC17 (ZDHHC17) DHHC palmitoyltransferase family Q8IUH5
5' exonuclease Apollo (DCLRE1B) DNA repair metallo-beta-lactamase (DRMBL) family Q9H816
Alpha-enolase (ENO1) Enolase family P06733
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) Enoyl-CoA hydratase/isomerase family Q13011
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family P40939
DNA primase small subunit (PRIM1) Eukaryotic-type primase small subunit family P49642
Serine protease FAM111B (FAM111B) FAM111 family Q6SJ93
FAST kinase domain-containing protein 1, mitochondrial (FASTKD1) FAST kinase family Q53R41
Fructose-1,6-bisphosphatase 1 (FBP1) FBPase class 1 family P09467
Protein adenylyltransferase FICD (FICD) Fic family Q9BVA6
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) FKBP-type PPIase family P26885
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2) GART family; Aldehyde dehydrogenase family Q3SY69
Ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2) GDA1/CD39 NTPase family Q9Y5L3
Nucleoside diphosphate phosphatase ENTPD5 (ENTPD5) GDA1/CD39 NTPase family O75356
Glucose-fructose oxidoreductase domain-containing protein 1 (GFOD1) Gfo/Idh/MocA family Q9NXC2
Glutathione peroxidase 7 (GPX7) Glutathione peroxidase family Q96SL4
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Glyceraldehyde-3-phosphate dehydrogenase family P04406
Lysozyme g-like protein 1 (LYG1) Glycosyl hydrolase 23 family Q8N1E2
Hyaluronidase-2 (HYAL2) Glycosyl hydrolase 56 family Q12891
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) Glycosyltransferase 2 family Q8N4A0
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) Glycosyltransferase 4 family Q9H3H5
Alpha-1,3/1,6-mannosyltransferase ALG2 (ALG2) Glycosyltransferase group 1 family Q9H553
Eyes absent homolog 3 (EYA3) EYA family Q99504
Heat shock cognate 71 kDa protein (HSPA8) Heat shock protein 70 family P11142
F-box DNA helicase 1 (FBH1) Helicase family Q8NFZ0
Hexokinase-3 (HK3) Hexokinase family P52790
Histone deacetylase 6 (HDAC6) Histone deacetylase family Q9UBN7
Polyamine deacetylase HDAC10 (HDAC10) Histone deacetylase family Q969S8
Porphobilinogen deaminase (HMBS) HMBS family P08397
X-ray repair cross-complementing protein 6 (XRCC6) Ku70 family P12956
Glutathione S-transferase LANCL1 (LANCL1) LanC-like protein family O43813
L-lactate dehydrogenase A-like 6B (LDHAL6B) LDH family Q9BYZ2
L-lactate dehydrogenase B chain (LDHB) LDH family P07195
Phosphatidate phosphatase LPIN1 (LPIN1) Lipin family Q14693
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) RNA-metabolizing metallo-beta-lactamase-like family Q9UKF6
Dihydropyrimidinase-related protein 1 (CRMP1) Hydantoinase/dihydropyrimidinase family Q14194
Dihydropyrimidinase-related protein 5 (DPYSL5) Hydantoinase/dihydropyrimidinase family Q9BPU6
Methylmalonyl-CoA mutase, mitochondrial (MMUT) Methylmalonyl-CoA mutase family P22033
[F-actin]-monooxygenase MICAL2 (MICAL2) Mical family O94851
Double-strand break repair protein MRE11 (MRE11) MRE11/RAD32 family P49959
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2) MsrB Met sulfoxide reductase family Q9Y3D2
Histone acetyltransferase KAT5 (KAT5) MYST (SAS/MOZ) family Q92993
dTDP-D-glucose 4,6-dehydratase (TGDS) NAD(P)-dependent epimerase/dehydratase family O95455
Nucleoside diphosphate kinase homolog 5 (NME5) NDK family P56597
Nucleoside diphosphate kinase, mitochondrial (NME4) NDK family O00746
Diphosphoinositol polyphosphate phosphohydrolase 2 (NUDT4) Nudix hydrolase family Q9NZJ9
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) P4HA family P13674
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (PDK2) PDK/BCKDK protein kinase family Q15119
E3 ubiquitin-protein ligase pellino homolog 1 (PELI1) Pellino family Q96FA3
Caspase-3 (CASP3) Peptidase C14A family P42574
Caspase-6 (CASP6) Peptidase C14A family P55212
Caspase-7 (CASP7) Peptidase C14A family P55210
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) Peptidase C19 family Q93008
Ubiquitin carboxyl-terminal hydrolase 24 (USP24) Peptidase C19 family Q9UPU5
Ubl carboxyl-terminal hydrolase 18 (USP18) Peptidase C19 family Q9UMW8
Calpain-10 (CAPN10) Peptidase C2 family Q9HC96
Cysteine protease ATG4C (ATG4C) Peptidase C54 family Q96DT6
Parkinson disease protein 7 (PARK7) Peptidase C56 family Q99497
MPN domain-containing protein (MPND) Peptidase M67 family Q8N594
26S proteasome non-ATPase regulatory subunit 7 (PSMD7) Peptidase M67A family P51665
26S proteasome non-ATPase regulatory subunit 14 (PSMD14) Peptidase M67A family O00487
Kallikrein-8 (KLK8) Peptidase S1 family O60259
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) Peptidase S14 family Q16740
Proteasome subunit alpha type-1 (PSMA1) Peptidase T1A family P25786
Proteasome subunit alpha type-4 (PSMA4) Peptidase T1A family P25789
Proteasome subunit alpha type-6 (PSMA6) Peptidase T1A family P60900
Proteasome subunit alpha type-7 (PSMA7) Peptidase T1A family O14818
Proteasome subunit beta type-1 (PSMB1) Peptidase T1B family P20618
Proteasome subunit beta type-2 (PSMB2) Peptidase T1B family P49721
Proteasome subunit beta type-3 (PSMB3) Peptidase T1B family P49720
Proteasome subunit beta type-6 (PSMB6) Peptidase T1B family P28072
Phenylalanine--tRNA ligase beta subunit (FARSB) Phenylalanyl-tRNA synthetase beta subunit family Q9NSD9
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PPP2R5E) Phosphatase 2A regulatory subunit B56 family Q16537
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) PI3/PI4-kinase family P42336
E3 SUMO-protein ligase PIAS1 (PIAS1) PIAS family O75925
E3 SUMO-protein ligase PIAS4 (PIAS4) PIAS family Q8N2W9
Protein prune homolog 2 (PRUNE2) PPase class C family Q8WUY3
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) PPP phosphatase family P62136
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) Proteasome subunit S3 family O43242
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) Proteasome subunit S5A family P55036
Endoplasmic reticulum resident protein 27 (ERP27) Protein disulfide isomerase family Q96DN0
Thioredoxin domain-containing protein 11 (TXNDC11) Protein disulfide isomerase family Q6PKC3
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) AGC Ser/Thr protein kinase family P17612
RAC-alpha serine/threonine-protein kinase (AKT1) AGC Ser/Thr protein kinase family P31749
MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) CAMK Ser/Thr protein kinase family Q9BUB5
Calcium/calmodulin-dependent protein kinase type 1 (CAMK1) CAMK Ser/Thr protein kinase family Q14012
Glycogen synthase kinase-3 alpha (GSK3A) CMGC Ser/Thr protein kinase family P49840
Serine/threonine-protein kinase NLK (NLK) CMGC Ser/Thr protein kinase family Q9UBE8
Serine/threonine-protein kinase Nek8 (NEK8) NEK Ser/Thr protein kinase family Q86SG6
Serine/threonine-protein kinase PINK1, mitochondrial (PINK1) Ser/Thr protein kinase family Q9BXM7
Serine/threonine-protein kinase ULK1 (ULK1) Ser/Thr protein kinase family O75385
Cell division cycle 7-related protein kinase (CDC7) Ser/Thr protein kinase family O00311
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) STE Ser/Thr protein kinase family Q99683
Serine/threonine-protein kinase PAK 2 (PAK2) STE Ser/Thr protein kinase family Q13177
Serine/threonine-protein kinase PAK 5 (PAK5) STE Ser/Thr protein kinase family Q9P286
Serine/threonine-protein kinase TAO3 (TAOK3) STE Ser/Thr protein kinase family Q9H2K8
TGF-beta receptor type-2 (TGFBR2) TKL Ser/Thr protein kinase family P37173
Protein-tyrosine kinase 6 (PTK6) Tyr protein kinase family Q13882
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) Purine/pyrimidine phosphoribosyltransferase family P00492
Pyruvate kinase PKM (PKM) Pyruvate kinase family P14618
RNA exonuclease 4 (REXO4) REXO4 family Q9GZR2
N-acetylaspartylglutamate synthase A (RIMKLA) RimK family Q8IXN7
Zinc-regulated GTPase metalloprotein activator 1C (ZNG1C) SIMIBI class G3E GTPase family Q5JTY5
ADP-ribosylation factor-like protein 16 (ARL16) Arf family Q0P5N6
Ras-related protein Rab-35 (RAB35) Rab family Q15286
Ras-related protein Rab-5B (RAB5B) Rab family P61020
GTP-binding nuclear protein Ran (RAN) Ran family P62826
Ras-like protein family member 11A (RASL11A) Ras family Q6T310
Chromodomain-helicase-DNA-binding protein 3 (CHD3) SNF2/RAD54 helicase family Q12873
DNA excision repair protein ERCC-6-like (ERCC6L) SNF2/RAD54 helicase family Q2NKX8
Signal peptidase complex subunit 3 (SPCS3) SPCS3 family P61009
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (SSU72) SSU72 phosphatase family Q9NP77
Inactive C-alpha-formylglycine-generating enzyme 2 (SUMF2) Sulfatase-modifying factor family Q8NBJ7
Terminal nucleotidyltransferase 5B (TENT5B) TENT family Q96A09
Thioredoxin, mitochondrial (TXN2) Thioredoxin family Q99757
TNF receptor-associated factor 2 (TRAF2) TNF receptor-associated factor family Q12933
Dynamin-1 (DNM1) Dynamin/Fzo/YdjA family Q05193
Atlastin-1 (ATL1) GB1/RHD3 GTPase family Q8WXF7
RING finger protein 112 (RNF112) GB1/RHD3 GTPase family Q9ULX5
GTP-binding protein 4 (GTPBP4) OBG GTPase family Q9BZE4
Elongation factor 2 (EEF2) Classic translation factor GTPase family P13639
Elongation factor 1-alpha 2 (EEF1A2) Classic translation factor GTPase family Q05639
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) Classic translation factor GTPase family P41091
GTPase IMAP family member 2 (GIMAP2) AIG1/Toc34/Toc159-like paraseptin GTPase family Q9UG22
Septin-4 (SEPTIN4) Septin GTPase family O43236
Septin-6 (SEPTIN6) Septin GTPase family Q14141
Transaldolase (TALDO1) Transaldolase family P37837
E3 ubiquitin-protein ligase TRIM21 (TRIM21) TRIM/RBCC family P19474
Tripartite motif-containing protein 49 (TRIM49) TRIM/RBCC family P0CI25
Triosephosphate isomerase (TPI1) Triosephosphate isomerase family P60174
Tubulin alpha-1A chain (TUBA1A) Tubulin family Q71U36
Ubiquitin-like modifier-activating enzyme 1 (UBA1) Ubiquitin-activating E1 family P22314
SUMO-conjugating enzyme UBC9 (UBE2I) Ubiquitin-conjugating enzyme family P63279
Ubiquitin-conjugating enzyme E2 D4 (UBE2D4) Ubiquitin-conjugating enzyme family Q9Y2X8
Ubiquitin-conjugating enzyme E2 H (UBE2H) Ubiquitin-conjugating enzyme family P62256
Ubiquitin-conjugating enzyme E2 K (UBE2K) Ubiquitin-conjugating enzyme family P61086
Small ribosomal subunit protein uS3 (RPS3) Universal ribosomal protein uS3 family P23396
Synaptic vesicle membrane protein VAT-1 homolog-like (VAT1L) Zinc-containing alcohol dehydrogenase family Q9HCJ6
CREB-binding protein (CREBBP) . Q92793
Cytosolic phospholipase A2 gamma (PLA2G4C) . Q9UP65
E3 ubiquitin-protein ligase CBL (CBL) . P22681
E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1) . Q9NPC3
E3 ubiquitin-protein ligase CHIP (STUB1) . Q9UNE7
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
E3 ubiquitin-protein ligase makorin-2 (MKRN2) . Q9H000
E3 ubiquitin-protein ligase RNF183 (RNF183) . Q96D59
Fatty acid synthase (FASN) . P49327
G2/M phase-specific E3 ubiquitin-protein ligase (G2E3) . Q7L622
LON peptidase N-terminal domain and RING finger protein 2 (LONRF2) . Q1L5Z9
Methyltransferase-like protein 27 (METTL27) . Q8N6F8
NEDD4-like E3 ubiquitin-protein ligase WWP2 (WWP2) . O00308
pre-mRNA splicing regulator USH1G (USH1G) . Q495M9
Ras GTPase-activating protein-binding protein 1 (G3BP1) . Q13283
Transporter and channel
Click To Hide/Show 52 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Amyloid-beta precursor protein (APP) APP family P05067
ATP synthase subunit alpha, mitochondrial (ATP5F1A) ATPase alpha/beta chains family P25705
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) ATPase alpha/beta chains family P21281
ATP synthase subunit O, mitochondrial (ATP5PO) ATPase delta chain family P48047
Flotillin-1 (FLOT1) Band 7/mec-2 family O75955
B-cell receptor-associated protein 31 (BCAP31) BCAP29/BCAP31 family P51572
Beclin-1 (BECN1) Beclin family Q14457
Clarin-3 (CLRN3) Clarin family Q8NCR9
Glioma pathogenesis-related protein 1 (GLIPR1) CRISP family P48060
Choline transporter-like protein 5 (SLC44A5) CTL (choline transporter-like) family Q8NCS7
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) Cytochrome c oxidase subunit 5B family P10606
Excitatory amino acid transporter 2 (SLC1A2) Dicarboxylate/amino acid:cation symporter (DAACS) family P43004
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) Eukaryotic ATPase B chain family P24539
Voltage-dependent anion-selective channel protein 2 (VDAC2) Eukaryotic mitochondrial porin family P45880
Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) HEY family Q9UBP5
Huntingtin (HTT) Huntingtin family P42858
Importin subunit alpha-4 (KPNA3) Importin alpha family O00505
Importin-4 (IPO4) Importin beta family Q8TEX9
Calcium-activated potassium channel subunit beta-2 (KCNMB2) KCNMB (TC 8.A.14.1) family Q9Y691
Dihydropyrimidinase-related protein 2 (DPYSL2) Hydantoinase/dihydropyrimidinase family Q16555
MICOS complex subunit MIC60 (IMMT) MICOS complex subunit Mic60 family Q16891
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) Mitochondrial carrier (TC 2.A.29) family Q02978
BOS complex subunit NCLN (NCLN) Nicastrin family Q969V3
Peroxisome proliferator-activated receptor alpha (PPARA) Nuclear hormone receptor family Q07869
Nucleoporin p58/p45 (NUP58) NUP58 family Q9BVL2
Cellular tumor antigen p53 (TP53) P53 family P04637
Major prion protein (PRNP) Prion family P04156
Ran GTPase-activating protein 1 (RANGAP1) RNA1 family P46060
Exocyst complex component 5 (EXOC5) SEC10 family O00471
Voltage-gated potassium channel subunit beta-2 (KCNAB2) Shaker potassium channel beta subunit family Q13303
Huntingtin-interacting protein 1 (HIP1) SLA2 family O00291
Alpha-crystallin A chain (CRYAA) Small heat shock protein (HSP20) family P02489
Sorting nexin-12 (SNX12) Sorting nexin family Q9UMY4
Sorting nexin-2 (SNX2) Sorting nexin family O60749
Sorting nexin-33 (SNX33) Sorting nexin family Q8WV41
Syntaxin-binding protein 1 (STXBP1) STXBP/unc-18/SEC1 family P61764
Synaptophysin (SYP) Synaptophysin/synaptobrevin family P08247
Alpha-synuclein (SNCA) Synuclein family P37840
Transmembrane protein 106B (TMEM106B) TMEM106 family Q9NUM4
Transmembrane protein 205 (TMEM205) TMEM205 family Q6UW68
Transmembrane protein 47 (TMEM47) TMEM47 family Q9BQJ4
V-type proton ATPase subunit H (ATP6V1H) V-ATPase H subunit family Q9UI12
V-type proton ATPase subunit d 1 (ATP6V0D1) V-ATPase V0D/AC39 subunit family P61421
V-type proton ATPase subunit S1 (ATP6AP1) Vacuolar ATPase subunit S1 family Q15904
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) WD repeat G protein beta family P62873
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) WD repeat G protein beta family P62879
mRNA export factor RAE1 (RAE1) WD repeat rae1 family P78406
Adiponectin (ADIPOQ) . Q15848
Optineurin (OPTN) . Q96CV9
Syntenin-1 (SDCBP) . O00560
TBC1 domain family member 5 (TBC1D5) . Q92609
Uncharacterized protein CXorf38 (CXorf38) . Q8TB03
Transcription factor
Click To Hide/Show 66 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C11 (HOXC11) Abd-B homeobox family O43248
Homeobox protein Hox-A5 (HOXA5) Antp homeobox family P20719
Homeobox protein Hox-C4 (HOXC4) Antp homeobox family P09017
Basic leucine zipper transcriptional factor ATF-like (BATF) BZIP family Q16520
Cyclic AMP-responsive element-binding protein 1 (CREB1) BZIP family P16220
Cell division cycle 5-like protein (CDC5L) CEF1 family Q99459
Homeobox protein DLX-3 (DLX3) Distal-less homeobox family O60479
Transcription factor E2F8 (E2F8) E2F/DP family A0AVK6
Transcription factor Spi-B (SPIB) ETS family Q01892
G-protein coupled receptor-associated sorting protein 2 (GPRASP2) GPRASP family Q96D09
High mobility group protein B1 (HMGB1) HMGB family P09429
Krueppel-like factor 3 (KLF3) Krueppel C2H2-type zinc-finger protein family P57682
Zinc finger and BTB domain-containing protein 16 (ZBTB16) Krueppel C2H2-type zinc-finger protein family Q05516
Zinc finger and SCAN domain-containing protein 9 (ZSCAN9) Krueppel C2H2-type zinc-finger protein family O15535
Zinc finger protein 138 (ZNF138) Krueppel C2H2-type zinc-finger protein family P52744
Zinc finger protein 19 (ZNF19) Krueppel C2H2-type zinc-finger protein family P17023
Zinc finger protein 2 (ZNF2) Krueppel C2H2-type zinc-finger protein family Q9BSG1
Zinc finger protein 281 (ZNF281) Krueppel C2H2-type zinc-finger protein family Q9Y2X9
Zinc finger protein 286A (ZNF286A) Krueppel C2H2-type zinc-finger protein family Q9HBT8
Zinc finger protein 436 (ZNF436) Krueppel C2H2-type zinc-finger protein family Q9C0F3
Zinc finger protein 497 (ZNF497) Krueppel C2H2-type zinc-finger protein family Q6ZNH5
Zinc finger protein 500 (ZNF500) Krueppel C2H2-type zinc-finger protein family O60304
Zinc finger protein 57 (ZNF57) Krueppel C2H2-type zinc-finger protein family Q68EA5
Zinc finger protein 572 (ZNF572) Krueppel C2H2-type zinc-finger protein family Q7Z3I7
Zinc finger protein 655 (ZNF655) Krueppel C2H2-type zinc-finger protein family Q8N720
Zinc finger protein 697 (ZNF697) Krueppel C2H2-type zinc-finger protein family Q5TEC3
Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) Krueppel C2H2-type zinc-finger protein family Q9BRR0
Zinc finger protein with KRAB and SCAN domains 8 (ZKSCAN8) Krueppel C2H2-type zinc-finger protein family Q15776
Zinc finger protein ZFP2 (ZFP2) Krueppel C2H2-type zinc-finger protein family Q6ZN57
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) LRRFIP family Q32MZ4
Homeobox protein MSX-2 (MSX2) Msh homeobox family P35548
Nuclear receptor corepressor 1 (NCOR1) N-CoR nuclear receptor corepressors family O75376
NAC-alpha domain-containing protein 1 (NACAD) NAC-alpha family O15069
Peroxisome proliferator-activated receptor gamma (PPARG) Nuclear hormone receptor family P37231
Retinoic acid receptor RXR-gamma (RXRG) Nuclear hormone receptor family P48443
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Krueppel-like factor 12 (KLF12) Sp1 C2H2-type zinc-finger protein family Q9Y4X4
Transcription factor Sp3 (SP3) Sp1 C2H2-type zinc-finger protein family Q02447
Transcription factor Sp6 (SP6) Sp1 C2H2-type zinc-finger protein family Q3SY56
Sterol regulatory element-binding protein 1 (SREBF1) SREBP family P36956
Pre-B-cell leukemia transcription factor 4 (PBX4) TALE/PBX homeobox family Q9BYU1
Zinc fingers and homeoboxes protein 1 (ZHX1) ZHX family Q9UKY1
Zinc finger protein ZXDC (ZXDC) ZXD family Q2QGD7
Achaete-scute homolog 4 (ASCL4) . Q6XD76
Deoxynucleotidyltransferase terminal-interacting protein 1 (DNTTIP1) . Q9H147
DNA-binding protein inhibitor ID-2 (ID2) . Q02363
Forkhead box protein D4-like 6 (FOXD4L6) . Q3SYB3
Forkhead box protein R1 (FOXR1) . Q6PIV2
High mobility group protein 20A (HMG20A) . Q9NP66
Homeobox protein MOX-1 (MEOX1) . P50221
LIM/homeobox protein Lhx5 (LHX5) . Q9H2C1
LIM/homeobox protein Lhx6 (LHX6) . Q9UPM6
LIM/homeobox protein Lhx8 (LHX8) . Q68G74
Methyl-CpG-binding domain protein 1 (MBD1) . Q9UIS9
Myeloid cell nuclear differentiation antigen (MNDA) . P41218
Neurogenic differentiation factor 1 (NEUROD1) . Q13562
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (HMG20B) . Q9P0W2
T-box brain protein 1 (TBR1) . Q16650
T-box transcription factor TBX22 (TBX22) . Q9Y458
Transcription factor HES-4 (HES4) . Q9HCC6
Transcription factor SOX-14 (SOX14) . O95416
Transcription factor SOX-7 (SOX7) . Q9BT81
Twist-related protein 1 (TWIST1) . Q15672
Twist-related protein 2 (TWIST2) . Q8WVJ9
Zinc finger protein 366 (ZNF366) . Q8N895
Zinc fingers and homeoboxes protein 1, isoform 2 (ZHX1-C8orf76) . Q96EF9
GPCR
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Membrane progestin receptor alpha (PAQR7) ADIPOR family Q86WK9
Probable G-protein coupled receptor 141 (GPR141) G-protein coupled receptor 1 family Q7Z602
Frizzled-4 (FZD4) G-protein coupled receptor Fz/Smo family Q9ULV1
Cytokine and receptor
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Granulocyte-macrophage colony-stimulating factor (CSF2) GM-CSF family P04141
Tumor necrosis factor ligand superfamily member 15 (TNFSF15) Tumor necrosis factor family O95150
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) . O00300
Other
Click To Hide/Show 347 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
14-3-3 protein beta/alpha (YWHAB) 14-3-3 family P31946
Mth938 domain-containing protein (AAMDC) AAMDC family Q9H7C9
Drebrin-like protein (DBNL) ABP1 family Q9UJU6
Beta-centractin (ACTR1B) Actin family P42025
AP-3 complex subunit beta-1 (AP3B1) Adaptor complexes large subunit family O00203
AP-3 complex subunit mu-1 (AP3M1) Adaptor complexes medium subunit family Q9Y2T2
Coatomer subunit delta (ARCN1) Adaptor complexes medium subunit family P48444
Serrate RNA effector molecule homolog (SRRT) ARS2 family Q9BXP5
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1) BACURD family Q13829
Catenin beta-1 (CTNNB1) Beta-catenin family P35222
Beta-crystallin A2 (CRYBA2) Beta/gamma-crystallin family P53672
Protein BEX3 (BEX3) BEX family Q00994
Cdc42 effector protein 4 (CDC42EP4) BORG/CEP family Q9H3Q1
Protein BRICK1 (BRK1) BRK1 family Q8WUW1
Nuclear nucleic acid-binding protein C1D (C1D) C1D family Q13901
Transgelin-2 (TAGLN2) Calponin family P37802
Centrin-2 (CETN2) Centrin family P41208
Deuterosome assembly protein 1 (DEUP1) CEP63 family Q05D60
Lipid transferase CIDEB (CIDEB) CIDE family Q9UHD4
CCR4-NOT transcription complex subunit 10 (CNOT10) CNOT10 family Q9H9A5
Conserved oligomeric Golgi complex subunit 8 (COG8) COG8 family Q96MW5
Reticulocalbin-1 (RCN1) CREC family Q15293
Adapter molecule crk (CRK) CRK family P46108
Pre-mRNA-splicing factor SYF1 (XAB2) Crooked-neck family Q9HCS7
Cyclin-C (CCNC) Cyclin family P24863
G1/S-specific cyclin-E2 (CCNE2) Cyclin family O96020
Cyclin-G1 (CCNG1) Cyclin family P51959
Death domain-associated protein 6 (DAXX) DAXX family Q9UER7
DAP3-binding cell death enhancer 1 (DELE1) DELE1 family Q14154
DnaJ homolog subfamily C member 11 (DNAJC11) DNAJC11 family Q9NVH1
Dynactin subunit 2 (DCTN2) Dynactin subunit 2 family Q13561
Dynactin subunit 4 (DCTN4) Dynactin subunit 4 family Q9UJW0
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) Dynein heavy chain family Q14204
Dynein light chain 1, cytoplasmic (DYNLL1) Dynein light chain family P63167
Chromatin modification-related protein MEAF6 (MEAF6) EAF6 family Q9HAF1
Elongation factor 1-beta (EEF1B2) EF-1-beta/EF-1-delta family P24534
Elongation factor 1-delta (EEF1D) EF-1-beta/EF-1-delta family P29692
EF-hand calcium-binding domain-containing protein 4B (CRACR2A) EFCAB4 family Q9BSW2
Eukaryotic translation initiation factor 1A, Y-chromosomal (EIF1AY) EIF-1A family O14602
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) EIF-2-beta/eIF-5 family P20042
Eukaryotic translation initiation factor 5 (EIF5) EIF-2-beta/eIF-5 family P55010
Eukaryotic translation initiation factor 3 subunit G (EIF3G) EIF-3 subunit G family O75821
Eukaryotic translation initiation factor 3 subunit I (EIF3I) EIF-3 subunit I family Q13347
Elongator complex protein 1 (ELP1) ELP1/IKA1 family O95163
Endophilin-A2 (SH3GL1) Endophilin family Q99961
Endophilin-A3 (SH3GL3) Endophilin family Q99963
Endophilin-B2 (SH3GLB2) Endophilin family Q9NR46
Activator of basal transcription 1 (ABT1) ESF2/ABP1 family Q9ULW3
Eukaryotic translation initiation factor 4E type 2 (EIF4E2) Eukaryotic initiation factor 4E family O60573
Protein pelota homolog (PELO) Eukaryotic release factor 1 family Q9BRX2
Large ribosomal subunit protein eL13 (RPL13) Eukaryotic ribosomal protein eL13 family P26373
Large ribosomal subunit protein eL15 (RPL15) Eukaryotic ribosomal protein eL15 family P61313
Large ribosomal subunit protein eL18 (RPL18) Eukaryotic ribosomal protein eL18 family Q07020
Large ribosomal subunit protein eL19 (RPL19) Eukaryotic ribosomal protein eL19 family P84098
Large ribosomal subunit protein eL22 (RPL22) Eukaryotic ribosomal protein eL22 family P35268
Large ribosomal subunit protein eL27 (RPL27) Eukaryotic ribosomal protein eL27 family P61353
Large ribosomal subunit protein eL31 (RPL31) Eukaryotic ribosomal protein eL31 family P62899
H/ACA ribonucleoprotein complex subunit 2 (NHP2) Eukaryotic ribosomal protein eL8 family Q9NX24
Small ribosomal subunit protein eS12 (RPS12) Eukaryotic ribosomal protein eS12 family P25398
Small ribosomal subunit protein eS19 (RPS19) Eukaryotic ribosomal protein eS19 family P39019
Armadillo repeat-containing X-linked protein 5 (ARMCX5) Eutherian X-chromosome-specific Armcx family Q6P1M9
Hsc70-interacting protein (ST13) FAM10 family P50502
Protein FAM163A (FAM163A) FAM163 family Q96GL9
Protein FAM167A (FAM167A) FAM167 (SEC) family Q96KS9
Protein FAM78A (FAM78A) FAM78 family Q5JUQ0
Protein FAM9A (FAM9A) FAM9 family Q8IZU1
Ferritin light chain (FTL) Ferritin family P02792
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) Fibulin family Q12805
Guanine nucleotide-binding protein G(o) subunit alpha (GNAO1) G-alpha family P09471
GRB2-associated-binding protein 2 (GAB2) GAB family Q9UQC2
X antigen family member 3 (XAGE3) GAGE family Q8WTP9
Centromere protein V (CENPV) Gfa family Q7Z7K6
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Golgi phosphoprotein 3-like (GOLPH3L) GOLPH3/VPS74 family Q9H4A5
GRB2-related adapter protein (GRAP) GRB2/sem-5/DRK family Q13588
HAUS augmin-like complex subunit 7 (HAUS7) HAUS7 family Q99871
HCLS1-associated protein X-1 (HAX1) HAX1 family O00165
Heat shock 70 kDa protein 1A (HSPA1A) Heat shock protein 70 family P0DMV8
Heat shock-related 70 kDa protein 2 (HSPA2) Heat shock protein 70 family P54652
Histone H2B type 1-H (H2BC9) Histone H2B family Q93079
Histone H3.1 (H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12) Histone H3 family P68431
Histone H3.2 (H3C15; H3C14; H3C13) Histone H3 family Q71DI3
Histone H3.3C (H3-5) Histone H3 family Q6NXT2
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) Histone H4 family P62805
Baculoviral IAP repeat-containing protein 5 (BIRC5) IAP family O15392
Intraflagellar transport protein 57 homolog (IFT57) IFT57 family Q9NWB7
Inhibitor of growth protein 4 (ING4) ING family Q9UNL4
Axonemal dynein light intermediate polypeptide 1 (DNALI1) Inner dynein arm light chain family O14645
Desmin (DES) Intermediate filament family P17661
Glial fibrillary acidic protein (GFAP) Intermediate filament family P14136
Keratin, type I cuticular Ha3-II (KRT33B) Intermediate filament family Q14525
Keratin, type I cytoskeletal 18 (KRT18) Intermediate filament family P05783
Keratin, type I cytoskeletal 19 (KRT19) Intermediate filament family P08727
Keratin, type I cytoskeletal 20 (KRT20) Intermediate filament family P35900
Vimentin (VIM) Intermediate filament family P08670
Mitochondrial assembly of ribosomal large subunit protein 1 (MALSU1) Iojap/RsfS family Q96EH3
Janus kinase and microtubule-interacting protein 1 (JAKMIP1) JAKMIP family Q96N16
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 8-1 (KRTAP8-1) KRTAP type 8 family Q8IUC2
Keratin-associated protein 9-2 (KRTAP9-2) KRTAP type 9 family Q9BYQ4
Lebercilin-like protein (LCA5L) LCA5 family O95447
Late cornified envelope protein 1B (LCE1B) LCE family Q5T7P3
Protein LDOC1 (LDOC1) LDOC1 family O95751
Protein lin-28 homolog A (LIN28A) Lin-28 family Q9H9Z2
Putative RNA-binding protein Luc7-like 2 (LUC7L2) Luc7 family Q9Y383
Repressor of RNA polymerase III transcription MAF1 homolog (MAF1) MAF1 family Q9H063
Protein PALS1 (PALS1) MAGUK family Q8N3R9
Mediator of RNA polymerase II transcription subunit 15 (MED15) Mediator complex subunit 15 family Q96RN5
Mediator of RNA polymerase II transcription subunit 28 (MED28) Mediator complex subunit 28 family Q9H204
Mediator of RNA polymerase II transcription subunit 30 (MED30) Mediator complex subunit 30 family Q96HR3
Mediator of RNA polymerase II transcription subunit 31 (MED31) Mediator complex subunit 31 family Q9Y3C7
Metallothionein-2 (MT2A) Type 1 family P02795
MICOS complex subunit MIC19 (CHCHD3) MICOS complex subunit Mic19 family Q9NX63
MORF4 family-associated protein 1 (MRFAP1) MORF4 family-associated protein family Q9Y605
MORF4 family-associated protein 1-like 1 (MRFAP1L1) MORF4 family-associated protein family Q96HT8
Protein MTSS 1 (MTSS1) MTSS family O43312
Neuronal membrane glycoprotein M6-a (GPM6A) Myelin proteolipid protein family P51674
Nuclear receptor 2C2-associated protein (NR2C2AP) NR2C2AP family Q86WQ0
Nucleosome assembly protein 1-like 2 (NAP1L2) Nucleosome assembly protein (NAP) family Q9ULW6
Otogelin-like protein (OTOGL) Otogelin family Q3ZCN5
Phosphofurin acidic cluster sorting protein 1 (PACS1) PACS family Q6VY07
Protein kinase C and casein kinase substrate in neurons protein 1 (PACSIN1) PACSIN family Q9BY11
Palmdelphin (PALMD) Paralemmin family Q9NP74
Pescadillo homolog (PES1) Pescadillo family O00541
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) PI3K p85 subunit family P27986
Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2) PI3K p85 subunit family O00459
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) PI3K p85 subunit family Q92569
PIH1 domain-containing protein 2 (PIH1D2) PIH1 family Q8WWB5
Oocyte-secreted protein 2 (OOSP2) PLAC1 family Q86WS3
Periplakin (PPL) Plakin or cytolinker family O60437
Plectin (PLEC) Plakin or cytolinker family Q15149
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
Profilin-2 (PFN2) Profilin family P35080
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31) PRP31 family Q8WWY3
Pre-mRNA-processing factor 40 homolog A (PRPF40A) PRPF40 family O75400
Protein PRRC1 (PRRC1) PRRC1 family Q96M27
UV excision repair protein RAD23 homolog A (RAD23A) RAD23 family P54725
RNA-binding protein 5 (RBM5) RBM5/RBM10 family P52756
Calcipressin-3 (RCAN3) RCAN family Q9UKA8
RAD50-interacting protein 1 (RINT1) RINT1 family Q6NUQ1
Protein ripply2 (RIPPLY2) Ripply family Q5TAB7
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) RRM HNRPC family P07910
Splicing factor 3B subunit 3 (SF3B3) RSE1 family Q15393
RUS family member 1 (RUSF1) RUS1 family Q96GQ5
Protein S100-P (S100P) S-100 family P25815
Histone deacetylase complex subunit SAP30 (SAP30) SAP30 family O75446
Protein transport protein Sec23B (SEC23B) SEC23/SEC24 family Q15437
Splicing factor 3A subunit 3 (SF3A3) SF3A3 family Q12874
Sideroflexin-3 (SFXN3) Sideroflexin family Q9BWM7
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) Small Tim family O60220
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) SMARCD family Q96GM5
Alpha-soluble NSF attachment protein (NAPA) SNAP family P54920
Synaptosomal-associated protein 29 (SNAP29) SNAP-25 family O95721
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) SNF5 family Q12824
Charged multivesicular body protein 1a (CHMP1A) SNF7 family Q9HD42
Charged multivesicular body protein 2a (CHMP2A) SNF7 family O43633
Charged multivesicular body protein 4b (CHMP4B) SNF7 family Q9H444
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) SnRNP core protein family P62316
U6 snRNA-associated Sm-like protein LSm8 (LSM8) SnRNP Sm proteins family O95777
Small nuclear ribonucleoprotein F (SNRPF) SnRNP Sm proteins family P62306
SNW domain-containing protein 1 (SNW1) SNW family Q13573
Sperm protein associated with the nucleus on the X chromosome C (SPANXC) SPAN-X family Q9NY87
Spermatogenesis-associated protein 2-like protein (SPATA2L) SPATA2 family Q8IUW3
Splicing factor U2AF 35 kDa subunit (U2AF1) Splicing factor SR family Q01081
Signal transducing adapter molecule 2 (STAM2) STAM family O75886
CST complex subunit STN1 (STN1) STN1 family Q9H668
Sec1 family domain-containing protein 1 (SCFD1) STXBP/unc-18/SEC1 family Q8WVM8
Symplekin (SYMPK) Symplekin family Q92797
Synaptotagmin-2 (SYT2) Synaptotagmin family Q8N9I0
Synaptotagmin-3 (SYT3) Synaptotagmin family Q9BQG1
Transforming acidic coiled-coil-containing protein 1 (TACC1) TACC family O75410
Centromere protein S (CENPS) TAF9 family Q8N2Z9
Protein TASOR 2 (TASOR2) TASOR family Q5VWN6
T-complex protein 1 subunit alpha (TCP1) TCP-1 chaperonin family P17987
T-complex protein 1 subunit beta (CCT2) TCP-1 chaperonin family P78371
T-complex protein 1 subunit epsilon (CCT5) TCP-1 chaperonin family P48643
T-complex protein 1 subunit theta (CCT8) TCP-1 chaperonin family P50990
T-complex protein 1 subunit zeta (CCT6A) TCP-1 chaperonin family P40227
T-complex protein 10A homolog 1 (TCP10L) TCP10 family Q8TDR4
CST complex subunit TEN1 (TEN1) TEN1 family Q86WV5
Tigger transposable element-derived protein 1 (TIGD1) Tigger transposable element derived protein family Q96MW7
Translation machinery-associated protein 16 (TMA16) TMA16 family Q96EY4
Transmembrane protein 115 (TMEM115) TMEM115 family Q12893
Transmembrane protein 43 (TMEM43) TMEM43 family Q9BTV4
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) Tom22 family Q9NS69
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) TTC19 family Q6DKK2
Tubulin beta chain (TUBB) Tubulin family P07437
Tubulin beta-6 chain (TUBB6) Tubulin family Q9BUF5
Polyubiquitin-C (UBC) Ubiquitin family P0CG48
Small ubiquitin-related modifier 1 (SUMO1) Ubiquitin family P63165
Small ubiquitin-related modifier 3 (SUMO3) Ubiquitin family P55854
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) Ubiquitin family; Eukaryotic ribosomal protein eS31 family P62979
Ubiquitin recognition factor in ER-associated degradation protein 1 (UFD1) UFD1 family Q92890
Large ribosomal subunit protein uL13m (MRPL13) Universal ribosomal protein uL13 family Q9BYD1
Ribosomal protein uL24-like (RPL26L1) Universal ribosomal protein uL24 family Q9UNX3
Large ribosomal subunit protein uL4 (RPL4) Universal ribosomal protein uL4 family P36578
Small ribosomal subunit protein uS7 (RPS5) Universal ribosomal protein uS7 family P46782
Small ribosomal subunit protein uS8 (RPS15A) Universal ribosomal protein uS8 family P62244
Bublin coiled-coil protein (BBLN) UPF0184 (EST00098) family Q9BUW7
U3 small nucleolar RNA-associated protein 14 homolog A (UTP14A) UTP14 family Q9BVJ6
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) UTP6 family Q9NYH9
Protein VAC14 homolog (VAC14) VAC14 family Q08AM6
Vacuolar protein sorting-associated protein 28 homolog (VPS28) VPS28 family Q9UK41
Vacuolar protein sorting-associated protein 37A (VPS37A) VPS37 family Q8NEZ2
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) WAL family Q9NRL2
DDB1- and CUL4-associated factor 7 (DCAF7) WD repeat DCAF7 family P61962
TLE family member 5 (TLE5) WD repeat Groucho/TLE family Q08117
POC1 centriolar protein homolog A (POC1A) WD repeat POC1 family Q8NBT0
Serine-threonine kinase receptor-associated protein (STRAP) WD repeat STRAP family Q9Y3F4
WD repeat-containing protein 91 (WDR91) WD repeat WDR91 family A4D1P6
Protein YIF1A (YIF1A) YIF1 family O95070
Zinc finger CCHC domain-containing protein 12 (ZCCHC12) ZCCHC12 family Q6PEW1
Fasciculation and elongation protein zeta-1 (FEZ1) Zygin family Q99689
Fasciculation and elongation protein zeta-2 (FEZ2) Zygin family Q9UHY8
Thyroid receptor-interacting protein 6 (TRIP6) Zyxin/ajuba family Q15654
40-kDa huntingtin-associated protein (F8A1; F8A2; F8A3) . P23610
Abscission/NoCut checkpoint regulator (ZFYVE19) . Q96K21
ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3) . Q9NP61
ARF GTPase-activating protein GIT1 (GIT1) . Q9Y2X7
Arfaptin-2 (ARFIP2) . P53365
BTB/POZ domain-containing protein KCTD17 (KCTD17) . Q8N5Z5
C-type lectin domain family 11 member A (CLEC11A) . Q9Y240
C-type lectin domain family 2 member B (CLEC2B) . Q92478
Cadherin-13 (CDH13) . P55290
Calicin (CCIN) . Q13939
CD59 glycoprotein (CD59) . P13987
CDK-activating kinase assembly factor MAT1 (MNAT1) . P51948
Cell division cycle-associated protein 7 (CDCA7) . Q9BWT1
Centrosomal protein of 126 kDa (CEP126) . Q9P2H0
Centrosomal protein of 55 kDa (CEP55) . Q53EZ4
Chromobox protein homolog 1 (CBX1) . P83916
Ciliary-associated calcium-binding coiled-coil protein 1 (CABCOCO1) . Q8IVU9
Coatomer subunit beta (COPB1) . P53618
Coiled-coil domain-containing protein 120 (CCDC120) . Q96HB5
Coiled-coil domain-containing protein 9 (CCDC9) . Q9Y3X0
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) . Q9Y6H1
Complement C1q tumor necrosis factor-related protein 3 (C1QTNF3) . Q9BXJ4
Cysteine and glycine-rich protein 3 (CSRP3) . P50461
DAZ-associated protein 2 (DAZAP2) . Q15038
DENN domain-containing protein 2B (DENND2B) . P78524
DnaJ homolog subfamily A member 1 (DNAJA1) . P31689
DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3) . Q96EY1
DnaJ homolog subfamily B member 4 (DNAJB4) . Q9UDY4
DnaJ homolog subfamily C member 21 (DNAJC21) . Q5F1R6
DnaJ homolog subfamily C member 4 (DNAJC4) . Q9NNZ3
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) . Q9UN19
Endothelial differentiation-related factor 1 (EDF1) . O60869
Enkurin (ENKUR) . Q8TC29
Ephexin-1 (NGEF) . Q8N5V2
Erythroid differentiation-related factor 1 (EDRF1) . Q3B7T1
Ezrin (EZR) . P15311
Fanconi anemia group F protein (FANCF) . Q9NPI8
Fibronectin type 3 and ankyrin repeat domains protein 1 (FANK1) . Q8TC84
FMR1-interacting protein NUFIP2 (NUFIP2) . Q7Z417
Formin-binding protein 4 (FNBP4) . Q8N3X1
Four and a half LIM domains protein 3 (FHL3) . Q13643
General transcription factor 3C polypeptide 3 (GTF3C3) . Q9Y5Q9
Glutamate-rich protein 2 (ERICH2) . A1L162
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) . Q8IV16
Grancalcin (GCA) . P28676
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) . P61978
HIRA-interacting protein 3 (HIRIP3) . Q9BW71
Huntingtin-interacting protein K (HYPK) . Q9NX55
Huntingtin-interacting protein M (H2AP) . O75409
INO80 complex subunit E (INO80E) . Q8NBZ0
Insulin-like growth factor-binding protein 4 (IGFBP4) . P22692
Kelch-like protein 12 (KLHL12) . Q53G59
Kelch-like protein 20 (KLHL20) . Q9Y2M5
La-related protein 4B (LARP4B) . Q92615
Leucine-rich repeat-containing protein 45 (LRRC45) . Q96CN5
Ligand of Numb protein X 2 (LNX2) . Q8N448
Lupus La protein (SSB) . P05455
Matrin-3 (MATR3) . P43243
Melanoma-associated antigen 3 (MAGEA3) . P43357
Melanoma-associated antigen B18 (MAGEB18) . Q96M61
Melanoma-associated antigen B6 (MAGEB6) . Q8N7X4
Methyl-CpG-binding protein 2 (MECP2) . P51608
Microspherule protein 1 (MCRS1) . Q96EZ8
Mortality factor 4-like protein 2 (MORF4L2) . Q15014
Nebulette (NEBL) . O76041
Necdin (NDN) . Q99608
Neutrophil cytosol factor 1 (NCF1) . P14598
Next to BRCA1 gene 1 protein (NBR1) . Q14596
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) . Q9Y239
Osteoclast-stimulating factor 1 (OSTF1) . Q92882
Paired amphipathic helix protein Sin3a (SIN3A) . Q96ST3
PDZ and LIM domain protein 5 (PDLIM5) . Q96HC4
PDZK1-interacting protein 1 (PDZK1IP1) . Q13113
Placental protein 13-like (LGALS14) . Q8TCE9
Pleckstrin homology domain-containing family G member 7 (PLEKHG7) . Q6ZR37
Polyglutamine-binding protein 1 (PQBP1) . O60828
PRKCA-binding protein (PICK1) . Q9NRD5
Progesterone-induced-blocking factor 1 (PIBF1) . Q8WXW3
Protein MGARP (MGARP) . Q8TDB4
Protein phosphatase 1 regulatory inhibitor subunit 16B (PPP1R16B) . Q96T49
Protein TFG (TFG) . Q92734
Putative BPES syndrome breakpoint region protein (BPESC1) . Q9GZL8
Putative uncharacterized protein encoded by LINC00518 (LINC00518) . Q8N0U6
Putative uncharacterized protein LOC152225 . Q0VG73
Putative uncharacterized protein RUSC1-AS1 (RUSC1-AS1) . Q66K80
Rap guanine nucleotide exchange factor 4 (RAPGEF4) . Q8WZA2
Ras association domain-containing protein 2 (RASSF2) . P50749
Ras GTPase-activating protein 1 (RASA1) . P20936
Rho GTPase-activating protein 24 (ARHGAP24) . Q8N264
RING1 and YY1-binding protein (RYBP) . Q8N488
RUN and FYVE domain-containing protein 4 (RUFY4) . Q6ZNE9
Selenocysteine insertion sequence-binding protein 2 (SECISBP2) . Q96T21
Sequestosome-1 (SQSTM1) . Q13501
Serine protease inhibitor Kazal-type 13 (SPINK13) . Q1W4C9
SERTA domain-containing protein 1 (SERTAD1) . Q9UHV2
Shieldin complex subunit 1 (SHLD1) . Q8IYI0
SLIT-ROBO Rho GTPase-activating protein 1 (SRGAP1) . Q7Z6B7
SLIT-ROBO Rho GTPase-activating protein 2 (SRGAP2) . O75044
SLIT-ROBO Rho GTPase-activating protein 3 (SRGAP3) . O43295
Small kinetochore-associated protein (KNSTRN) . Q9Y448
Sorbin and SH3 domain-containing protein 1 (SORBS1) . Q9BX66
Sperm-associated microtubule inner protein 4 (SPMIP4) . Q8N865
Spermatogenesis-associated protein 12 (SPATA12) . Q7Z6I5
Spermatogenesis-associated protein 22 (SPATA22) . Q8NHS9
Spindle assembly abnormal protein 6 homolog (SASS6) . Q6UVJ0
Splicing regulator RBM11 (RBM11) . P57052
Sprouty-related, EVH1 domain-containing protein 2 (SPRED2) . Q7Z698
Steroidogenic acute regulatory protein, mitochondrial (STAR) . P49675
Superkiller complex protein 8 (SKIC8) . Q9GZS3
Suppressor of cytokine signaling 4 (SOCS4) . Q8WXH5
Synaptonemal complex central element protein 3 (SYCE3) . A1L190
Testis-specific expressed protein 55 (TEX55) . Q96M34
Tetratricopeptide repeat protein 1 (TTC1) . Q99614
TNFAIP3-interacting protein 3 (TNIP3) . Q96KP6
TRAF family member-associated NF-kappa-B activator (TANK) . Q92844
TRAF-type zinc finger domain-containing protein 1 (TRAFD1) . O14545
Transcription elongation regulator 1 (TCERG1) . O14776
Transcription factor Gibbin (AHDC1) . Q5TGY3
Trefoil factor 2 (TFF2) . Q03403
Ubiquilin-2 (UBQLN2) . Q9UHD9
Ubiquitin-associated domain-containing protein 1 (UBAC1) . Q9BSL1
Uncharacterized protein C1orf94 (C1orf94) . Q6P1W5
Uncharacterized protein C20orf141 (C20orf141) . Q9NUB4
Uncharacterized protein C7orf50 (C7orf50) . Q9BRJ6
Uncharacterized protein KIAA0408 (KIAA0408) . Q6ZU52
VIP36-like protein (LMAN2L) . Q9H0V9
WD repeat and FYVE domain-containing protein 3 (WDFY3) . Q8IZQ1
WW domain-binding protein 4 (WBP4) . O75554
WW domain-containing adapter protein with coiled-coil (WAC) . Q9BTA9
Z-DNA-binding protein 1 (ZBP1) . Q9H171
Zinc finger matrin-type protein 2 (ZMAT2) . Q96NC0

The Drug(s) Related To This Target

Approved
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Copper . DB09130
Preclinical
Click To Hide/Show 2 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Huntingtin Gene Antisense Antisense drug D00QIJ
Aln-htt RNAi therapeutics D0V7VX

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 A Chemical Proteomic Probe for the Mitochondrial Pyruvate Carrier Complex. Angew Chem Int Ed Engl. 2020 Mar 2;59(10):3896-3899. doi: 10.1002/anie.201914391. Epub 2020 Feb 11.
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
7 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
8 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
9 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
10 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
11 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
14 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
15 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578