General Information of Experiment

Probe Name C179  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 11 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03374  Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) 60.1
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 14.5
 LDTP05372  Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) 14.4
 LDTP01562  Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) 13.8
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 12.7
 LDTP06645  Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) 9.3
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 7.4
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 6.8
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 6.3
 LDTP01707  Thioredoxin domain-containing protein 12 (TXNDC12) 5.9
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) 5.5
Transporter and channel
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 22.9
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 19.0
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 11.2
 LDTP04592  Monocarboxylate transporter 1 (SLC16A1) 7.8
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 7.7
Other
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15623  Neuferricin (CYB5D2) 24.3
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 12.0
 LDTP11328  Splicing factor 3B subunit 5 (SF3B5) 7.3
 LDTP11825  Phosducin-like protein 3 (PDCL3) 6.3
 LDTP13630  Neudesin (NENF) 5.4

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587