General Information of Experiment

Probe Name IA-alkyne  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
Isotope tag
Competitor Name EV-3  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cell lysate (T cell)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 22 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP05893  Baculoviral IAP repeat-containing protein 2 (BIRC2) C45 20.0
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) C32 20.0
 LDTP05943  Myotubularin-related protein 1 (MTMR1) C117 20.0
 LDTP12428  Omega-amidase NIT2 (NIT2) C153 20.0
 LDTP12784  Pyroglutamyl-peptidase 1 (PGPEP1) C149 20.0
 LDTP18123  Isochorismatase domain-containing protein 2 (ISOC2) C114 17.3
 LDTP03540  Heme oxygenase 2 (HMOX2) C282 14.7
 LDTP17247  5'-nucleotidase domain-containing protein 1 (NT5DC1) C119 13.9
 LDTP07407  Desumoylating isopeptidase 1 (DESI1) C108 13.8
 LDTP01707  Thioredoxin domain-containing protein 12 (TXNDC12) C66 13.2
 LDTP10676  Inositol polyphosphate-4-phosphatase type I A (INPP4A) C275, C286 10.7
 LDTP02852  Methylated-DNA--protein-cysteine methyltransferase (MGMT) C145 9.3
 LDTP03330  Proteasome subunit alpha type-1 (PSMA1) C148, C156 8.8
 LDTP14159  Ubiquitin carboxyl-terminal hydrolase 16 (USP16) C205 8.8
 LDTP01394  DNA fragmentation factor subunit beta (DFFB) C194 8.5
 LDTP05992  Bleomycin hydrolase (BLMH) C73 8.1
 LDTP11437  Peroxisomal trans-2-enoyl-CoA reductase (PECR) C191 5.9
 LDTP05927  G/T mismatch-specific thymine DNA glycosylase (TDG) C233 5.9
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) C286, C289 5.1
 LDTP03458  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) C296 4.8
 LDTP02765  Aldo-keto reductase family 1 member B1 (AKR1B1) C299, C304 4.5
 LDTP12539  DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) C130 4.1
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP03194  Granulysin (GNLY) C43, C45, C46 10.7
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP02338  CD48 antigen (CD48) C148 9.3
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP13515  Zinc finger protein 346 (ZNF346) C68 14.4
 LDTP04780  Ubiquitin-associated and SH3 domain-containing protein A (UBASH3A) C435 8.0
 LDTP10452  Conserved oligomeric Golgi complex subunit 3 (COG3) C65 7.6

References

1 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.