General Information of Experiment

Probe Name aONE  Probe Info 
Probe concentration 50 uM
Criteria Qualitation: Labeling site identification
Quantitative Method
Isotope tag
In Vivo Experiment Model Model Type Living cell
Derived Tissue Colon
Disease Model Colon carcinoma [ICD-11:2B90]
Model Name Human colon carcinoma cells (RKO)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP02159  Alpha-enolase (ENO1) K80
 LDTP02159  Alpha-enolase (ENO1) K5
 LDTP05077  Casein kinase II subunit alpha (CSNK2A1) K102
 LDTP07672  E3 ubiquitin-protein ligase LRSAM1 (LRSAM1) K138
 LDTP02672  Elongation factor 2 (EEF2) K318
 LDTP13401  Probable ATP-dependent RNA helicase DDX41 (DDX41) K366
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP03385  14-3-3 protein theta (YWHAQ) K9
 LDTP07361  Bridge-like lipid transfer protein family member 3A (BLTP3A) K255
 LDTP01116  Disintegrin and metalloproteinase domain-containing protein 11 (ADAM11) K278
Other
Click to Show/Hide to Show 19 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP18445  Fibrosin-1-like protein (FBRSL1) K118
 LDTP02364  Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) K106
 LDTP04495  Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) K127
 LDTP02845  Histone H1.2 (H1-2) K46
 LDTP02844  Histone H1.3 (H1-3) K47
 LDTP02494  Histone H1.4 (H1-4) K46
 LDTP06627  Histone H2A type 2-C (H2AC20) K120
 LDTP01054  Histone H2B type 1-K (H2BC12) K109
 LDTP01054  Histone H2B type 1-K (H2BC12) K117
 LDTP08787  Histone H2B type 3-B (H2BC26) K117
 LDTP08787  Histone H2B type 3-B (H2BC26) K109
 LDTP05004  Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) K78
 LDTP05004  Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) K92
 LDTP14736  NACHT, LRR and PYD domains-containing protein 11 (NLRP11) K172
 LDTP02990  Nucleolin (NCL) K398
 LDTP02218  Profilin-1 (PFN1) K108
 LDTP11520  Protocadherin-11 Y-linked (PCDH11Y) K96
 LDTP06880  Rho GTPase-activating protein 29 (ARHGAP29) K1059
 LDTP05522  Sperm-associated antigen 1 (SPAG1) K190

References

1 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764