Details of the Target

General Information of Target

Target ID LDTP19858
Target Name Protein KTI12 homolog (KTI12)
Gene Name KTI12
Gene ID 112970
Synonyms
Protein KTI12 homolog
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MFFTISRKNMSQKLSLLLLVFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKAL
AEENKNTVDVENGASMAGYADLKRTIAVLLDDILQRLVKLENKVDYIVVNGSAANTTNGT
SGNLVPVTTNKRTNVSGSIR
Target Bioclass
Other
Family
KTI12 family
Uniprot ID
Q96EK9
Ensemble ID
ENST00000371614.2
HGNC ID
HGNC:25160

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
Acrolein
 Probe Info  		N.A.  LDD0221  [2]
DBIA
 Probe Info  		C103(1.04); C107(1.04)  LDD0531  [3]
ATP probe
 Probe Info  		N.A.  LDD0199  [4]
m-APA
 Probe Info  		N.A.  LDD2232  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [6]
IA-alkyne
 Probe Info  		C7(0.00); C103(0.00); C107(0.00)  LDD0036  [6]
Lodoacetamide azide
 Probe Info  		C7(0.00); C93(0.00)  LDD0037  [6]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [7]
TFBX
 Probe Info  		N.A.  LDD0027  [7]
W1
 Probe Info  		N.A.  LDD0236  [1]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info  		N.A.  LDD0396  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C103(1.04); C107(1.04)  LDD0531  [3]
 LDCM0215  AC10 HEK-293T C103(1.06); C107(1.06)  LDD0813  [3]
 LDCM0216  AC100 HCT 116 C103(0.95); C107(0.95); C93(1.00)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C103(1.21); C107(1.18); C93(1.11)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C103(1.35); C107(1.29); C93(1.09)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C103(1.29); C107(1.26); C93(0.95)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C103(2.00); C107(1.97); C93(1.61)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C103(1.15); C107(1.16); C93(0.82)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C103(1.17); C107(1.25); C93(0.82)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C103(1.64); C107(1.69); C93(1.36)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C103(0.85); C107(0.93); C93(0.89)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C103(1.59); C107(1.55); C93(1.32)  LDD0542  [3]
 LDCM0226  AC11 HEK-293T C103(1.04); C107(1.04)  LDD0824  [3]
 LDCM0227  AC110 HCT 116 C103(1.49); C107(1.43); C93(0.96)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C103(2.37); C107(2.36); C93(1.25)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C103(1.72); C107(1.68); C93(1.03)  LDD0546  [3]
 LDCM0230  AC113 HEK-293T C93(0.66)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C93(0.62)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C93(0.61)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C93(0.83)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C93(0.86)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C93(0.65)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C93(0.78)  LDD0834  [3]
 LDCM0237  AC12 HEK-293T C103(1.32); C107(1.32)  LDD0835  [3]
 LDCM0238  AC120 HEK-293T C93(0.81)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C93(0.84)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C93(0.62)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C93(1.14)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C93(1.01)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C93(0.73)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C93(0.98)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C93(1.00)  LDD0843  [3]
 LDCM0246  AC128 HEK-293T C93(1.33)  LDD0844  [3]
 LDCM0247  AC129 HEK-293T C93(1.76)  LDD0845  [3]
 LDCM0249  AC130 HEK-293T C93(1.28)  LDD0847  [3]
 LDCM0250  AC131 HEK-293T C93(2.62)  LDD0848  [3]
 LDCM0251  AC132 HEK-293T C93(2.01)  LDD0849  [3]
 LDCM0252  AC133 HEK-293T C93(0.95)  LDD0850  [3]
 LDCM0253  AC134 HEK-293T C93(1.33)  LDD0851  [3]
 LDCM0254  AC135 HEK-293T C93(1.07)  LDD0852  [3]
 LDCM0255  AC136 HEK-293T C93(1.12)  LDD0853  [3]
 LDCM0256  AC137 HEK-293T C93(0.99)  LDD0854  [3]
 LDCM0257  AC138 HEK-293T C93(1.21)  LDD0855  [3]
 LDCM0258  AC139 HEK-293T C93(1.62)  LDD0856  [3]
 LDCM0259  AC14 HEK-293T C103(1.20); C107(1.20)  LDD0857  [3]
 LDCM0260  AC140 HEK-293T C93(1.37)  LDD0858  [3]
 LDCM0261  AC141 HEK-293T C93(1.22)  LDD0859  [3]
 LDCM0262  AC142 HEK-293T C93(1.25)  LDD0860  [3]
 LDCM0263  AC143 HEK-293T C103(1.12); C107(1.12); C93(0.86)  LDD0861  [3]
 LDCM0264  AC144 HEK-293T C103(1.21); C107(1.21); C93(0.95)  LDD0862  [3]
 LDCM0265  AC145 HEK-293T C103(2.85); C107(2.85); C93(1.00)  LDD0863  [3]
 LDCM0266  AC146 HEK-293T C103(2.27); C107(2.27); C93(1.19)  LDD0864  [3]
 LDCM0267  AC147 HEK-293T C103(2.45); C107(2.45); C93(0.88)  LDD0865  [3]
 LDCM0268  AC148 HEK-293T C103(2.48); C107(2.48); C93(0.71)  LDD0866  [3]
 LDCM0269  AC149 HEK-293T C103(1.86); C107(1.86); C93(0.81)  LDD0867  [3]
 LDCM0270  AC15 HEK-293T C103(1.12); C107(1.12)  LDD0868  [3]
 LDCM0271  AC150 HEK-293T C103(2.90); C107(2.90); C93(0.82)  LDD0869  [3]
 LDCM0272  AC151 HEK-293T C103(3.24); C107(3.24); C93(0.97)  LDD0870  [3]
 LDCM0273  AC152 HEK-293T C103(1.04); C107(1.04); C93(0.82)  LDD0871  [3]
 LDCM0274  AC153 HEK-293T C103(0.84); C107(0.84); C93(0.87)  LDD0872  [3]
 LDCM0621  AC154 HEK-293T C103(1.25); C107(1.25); C93(1.29)  LDD2162  [3]
 LDCM0622  AC155 HEK-293T C103(1.03); C107(1.03); C93(0.88)  LDD2163  [3]
 LDCM0623  AC156 HEK-293T C103(1.52); C107(1.52); C93(1.05)  LDD2164  [3]
 LDCM0624  AC157 HEK-293T C103(0.94); C107(0.94); C93(0.74)  LDD2165  [3]
 LDCM0276  AC17 HCT 116 C103(0.38); C107(0.38)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C103(1.41); C107(1.41)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C103(0.99); C107(0.99)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C103(0.84); C107(0.84)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C103(1.06); C107(1.06)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C103(0.91); C107(0.91)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C103(0.33); C107(0.33)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C103(0.58); C107(0.58)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C103(1.72); C107(1.72)  LDD0601  [3]
 LDCM0285  AC25 HEK-293T C93(1.15)  LDD1524  [10]
 LDCM0287  AC27 HEK-293T C93(1.17)  LDD1526  [10]
 LDCM0288  AC28 HEK-293T C93(0.98)  LDD1527  [10]
 LDCM0289  AC29 HEK-293T C93(1.00)  LDD1528  [10]
 LDCM0290  AC3 HCT 116 C103(0.91); C107(0.91)  LDD0607  [3]
 LDCM0291  AC30 HEK-293T C93(1.07)  LDD1530  [10]
 LDCM0292  AC31 HEK-293T C93(1.01)  LDD1531  [10]
 LDCM0294  AC33 HEK-293T C93(0.99)  LDD1533  [10]
 LDCM0296  AC35 HCT 116 C103(0.87); C107(0.87)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C103(0.95); C107(0.95)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C103(1.00); C107(1.00)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C103(0.84); C107(0.84)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C103(0.94); C107(0.94)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C103(0.88); C107(0.88)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C103(1.15); C107(1.15)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C103(1.08); C107(1.08)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C103(0.98); C107(0.98)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C103(0.97); C107(0.97)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C103(1.08); C107(1.08)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C103(1.19); C107(1.19)  LDD0624  [3]
 LDCM0308  AC46 HEK-293T C103(1.28); C107(1.28)  LDD0906  [3]
 LDCM0309  AC47 HEK-293T C103(1.17); C107(1.17)  LDD0907  [3]
 LDCM0310  AC48 HEK-293T C103(1.47); C107(1.47)  LDD0908  [3]
 LDCM0311  AC49 HEK-293T C103(0.75); C107(0.75)  LDD0909  [3]
 LDCM0312  AC5 HCT 116 C103(0.90); C107(0.90)  LDD0629  [3]
 LDCM0313  AC50 HEK-293T C103(1.16); C107(1.16)  LDD0911  [3]
 LDCM0314  AC51 HEK-293T C103(0.89); C107(0.89)  LDD0912  [3]
 LDCM0315  AC52 HEK-293T C103(2.21); C107(2.21)  LDD0913  [3]
 LDCM0316  AC53 HEK-293T C103(1.82); C107(1.82)  LDD0914  [3]
 LDCM0317  AC54 HEK-293T C103(1.89); C107(1.89)  LDD0915  [3]
 LDCM0318  AC55 HEK-293T C103(1.08); C107(1.08)  LDD0916  [3]
 LDCM0319  AC56 HEK-293T C103(1.25); C107(1.25)  LDD0917  [3]
 LDCM0320  AC57 HCT 116 C93(0.94)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C93(1.17)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C93(1.11)  LDD0639  [3]
 LDCM0323  AC6 HEK-293T C103(1.03); C107(1.03)  LDD0921  [3]
 LDCM0324  AC60 HCT 116 C93(1.09)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C93(1.12)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C93(1.14)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C93(1.30)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C93(1.27)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C93(1.12)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C93(1.48)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C93(1.61)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C93(0.91)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C93(0.94)  LDD0650  [3]
 LDCM0334  AC7 HEK-293T C103(0.97); C107(0.97)  LDD0932  [3]
 LDCM0335  AC70 HCT 116 C93(0.85)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C93(0.98)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C93(0.94)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C93(0.89)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C93(0.94)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C93(1.02)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C93(0.88)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C93(0.84)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C93(0.80)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C93(0.98)  LDD0661  [3]
 LDCM0345  AC8 HEK-293T C103(1.11); C107(1.11)  LDD0943  [3]
 LDCM0346  AC80 HCT 116 C93(0.97)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C93(0.86)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C93(1.16)  LDD0665  [3]
 LDCM0365  AC98 HCT 116 C107(0.89); C93(0.89); C103(0.91)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C93(0.84); C107(0.86); C103(0.92)  LDD0683  [3]
 LDCM0248  AKOS034007472 HEK-293T C103(1.01); C107(1.01)  LDD0846  [3]
 LDCM0356  AKOS034007680 HEK-293T C103(1.12); C107(1.12)  LDD0954  [3]
 LDCM0275  AKOS034007705 HEK-293T C103(1.25); C107(1.25)  LDD0873  [3]
 LDCM0632  CL-Sc Hep-G2 C7(1.31)  LDD2227  [8]
 LDCM0367  CL1 HCT 116 C93(0.93)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C93(1.11)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C103(0.98); C107(0.98)  LDD0686  [3]
 LDCM0370  CL101 HEK-293T C103(1.02); C107(1.02)  LDD0968  [3]
 LDCM0371  CL102 HEK-293T C103(1.22); C107(1.22)  LDD0969  [3]
 LDCM0372  CL103 HEK-293T C103(0.94); C107(0.94)  LDD0970  [3]
 LDCM0373  CL104 HEK-293T C103(0.96); C107(0.96)  LDD0971  [3]
 LDCM0374  CL105 HCT 116 C103(0.24); C107(0.24)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C103(0.22); C107(0.22)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C103(0.15); C107(0.15)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C103(0.17); C107(0.17)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C103(0.12); C107(0.12)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C93(0.87)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C103(0.25); C107(0.25)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C103(0.42); C107(0.42)  LDD0698  [3]
 LDCM0387  CL117 HCT 116 C103(1.52); C107(1.52)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C103(0.98); C107(0.98)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C103(1.08); C107(1.08)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C93(1.05)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C103(1.04); C107(1.04)  LDD0708  [3]
 LDCM0392  CL121 HEK-293T C103(1.64); C107(1.64)  LDD0990  [3]
 LDCM0393  CL122 HEK-293T C103(0.77); C107(0.77)  LDD0991  [3]
 LDCM0394  CL123 HEK-293T C103(0.84); C107(0.84)  LDD0992  [3]
 LDCM0395  CL124 HEK-293T C103(1.27); C107(1.27)  LDD0993  [3]
 LDCM0396  CL125 HCT 116 C93(0.96)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C93(1.33)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C93(0.97)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C93(0.94)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C93(1.21)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C93(1.17)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C93(0.94)  LDD0719  [3]
 LDCM0403  CL16 HEK-293T C103(0.78); C107(0.78)  LDD1001  [3]
 LDCM0404  CL17 HCT 116 C93(1.10)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C93(1.00)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C93(1.05)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C93(0.85)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C93(1.28)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C93(1.04)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C93(1.14)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C93(1.17)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C93(1.39)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C93(1.04)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C93(0.95)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C93(1.17)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C93(0.90)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C93(1.66)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C93(0.90)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C93(1.36)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C93(1.27)  LDD0737  [3]
 LDCM0421  CL32 HEK-293T C93(0.75)  LDD1019  [3]
 LDCM0422  CL33 HEK-293T C93(0.78)  LDD1020  [3]
 LDCM0423  CL34 HEK-293T C93(0.77)  LDD1021  [3]
 LDCM0424  CL35 HEK-293T C93(0.81)  LDD1022  [3]
 LDCM0425  CL36 HEK-293T C93(0.77)  LDD1023  [3]
 LDCM0426  CL37 HEK-293T C93(1.00)  LDD1024  [3]
 LDCM0428  CL39 HEK-293T C93(0.88)  LDD1026  [3]
 LDCM0429  CL4 HCT 116 C93(0.76)  LDD0746  [3]
 LDCM0430  CL40 HEK-293T C93(0.88)  LDD1028  [3]
 LDCM0431  CL41 HEK-293T C93(0.80)  LDD1029  [3]
 LDCM0432  CL42 HEK-293T C93(0.87)  LDD1030  [3]
 LDCM0433  CL43 HEK-293T C93(1.03)  LDD1031  [3]
 LDCM0434  CL44 HEK-293T C93(1.10)  LDD1032  [3]
 LDCM0435  CL45 HEK-293T C93(1.00)  LDD1033  [3]
 LDCM0436  CL46 HCT 116 C93(1.01)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C93(0.81)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C93(0.76)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C93(0.84)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C93(0.97)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C93(0.89)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C93(1.05)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C93(1.05)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C93(0.83)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C93(0.94)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C93(0.88)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C93(0.75)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C93(0.94)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C93(1.08)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C93(0.91)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C93(1.14)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C93(0.93)  LDD0769  [3]
 LDCM0453  CL61 HCT 116 C103(0.78); C107(0.78); C93(0.85)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C103(0.81); C107(0.81); C93(0.71)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C103(1.49); C107(1.49); C93(1.03)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C103(0.97); C107(0.97); C93(0.90)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C103(1.23); C107(1.23); C93(1.28)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C103(1.11); C107(1.11); C93(0.92)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C103(1.12); C107(1.12); C93(2.10)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C103(1.42); C107(1.42); C93(2.76)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C103(0.96); C107(0.96); C93(1.23)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C93(1.17)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C103(0.86); C107(0.86); C93(1.30)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C103(1.06); C107(1.06); C93(1.20)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C103(1.35); C107(1.35); C93(1.58)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C103(1.23); C107(1.23); C93(1.64)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C103(1.36); C107(1.36); C93(1.89)  LDD0784  [3]
 LDCM0469  CL76 HCT 116 C93(1.01)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C93(1.22)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C93(1.05)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C93(0.91)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C93(0.82)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C93(0.91)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C93(0.91)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C93(0.91)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C93(0.97)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C93(0.77)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C93(0.95)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C93(0.99)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C93(1.07)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C93(1.19)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C93(1.29)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C93(0.82)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C93(1.34)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C103(1.18); C107(1.18)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C103(1.35); C107(1.35)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C103(0.79); C107(0.79)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C103(1.16); C107(1.16)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C103(0.99); C107(0.99)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C103(1.34); C107(1.34)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C103(1.33); C107(1.33)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C103(0.91); C107(0.91)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C103(1.00); C107(1.00)  LDD0811  [3]
 LDCM0625  F8 Ramos C7(0.88); C93(0.83)  LDD2187  [11]
 LDCM0572  Fragment10 Ramos C7(0.53); C93(0.73)  LDD2189  [11]
 LDCM0573  Fragment11 Ramos C7(1.40)  LDD2190  [11]
 LDCM0574  Fragment12 Ramos C7(0.66); C93(0.83)  LDD2191  [11]
 LDCM0575  Fragment13 Ramos C7(0.67); C93(0.88)  LDD2192  [11]
 LDCM0576  Fragment14 Ramos C7(0.94); C93(0.85)  LDD2193  [11]
 LDCM0579  Fragment20 Ramos C7(0.48); C93(0.88)  LDD2194  [11]
 LDCM0580  Fragment21 Ramos C7(0.67); C93(0.87)  LDD2195  [11]
 LDCM0582  Fragment23 Ramos C7(0.52); C93(0.77)  LDD2196  [11]
 LDCM0578  Fragment27 Ramos C7(0.64); C93(0.98)  LDD2197  [11]
 LDCM0586  Fragment28 Ramos C7(1.13); C93(0.72)  LDD2198  [11]
 LDCM0588  Fragment30 Ramos C7(0.57); C93(0.74)  LDD2199  [11]
 LDCM0589  Fragment31 Ramos C7(0.72); C93(0.79)  LDD2200  [11]
 LDCM0590  Fragment32 Ramos C7(0.41); C93(0.65)  LDD2201  [11]
 LDCM0468  Fragment33 HCT 116 C103(1.24); C107(1.24); C93(1.01)  LDD0785  [3]
 LDCM0596  Fragment38 Ramos C7(1.00); C93(0.79)  LDD2203  [11]
 LDCM0566  Fragment4 Ramos C7(0.78); C93(0.76)  LDD2184  [11]
 LDCM0427  Fragment51 HEK-293T C93(1.30)  LDD1025  [3]
 LDCM0610  Fragment52 Ramos C7(0.93)  LDD2204  [11]
 LDCM0614  Fragment56 Ramos C7(0.65); C93(0.85)  LDD2205  [11]
 LDCM0569  Fragment7 Ramos C7(0.77); C93(0.63)  LDD2186  [11]
 LDCM0571  Fragment9 Ramos C7(0.73); C93(0.77)  LDD2188  [11]
 LDCM0107  IAA HeLa N.A.  LDD0221  [2]
 LDCM0022  KB02 HEK-293T C93(1.11)  LDD1492  [10]
 LDCM0023  KB03 HEK-293T C93(1.04)  LDD1497  [10]
 LDCM0024  KB05 MKN-1 C93(1.95)  LDD3331  [12]
 LDCM0109  NEM HeLa N.A.  LDD0223  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Four and a half LIM domains protein 3 (FHL3) . Q13643

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
5 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
12 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840