Details of the Target

General Information of Target

Target ID LDTP16125
Target Name Protein Abitram (ABITRAM)
Gene Name ABITRAM
Gene ID 54942
Synonyms
C9orf6; FAM206A; Protein Abitram; Actin-binding transcription modulator; Protein Simiate
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MWRLLARASAPLLRVPLSDSWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVP
KVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFA
IWRVPAPFKPITRKSVGHRMGGGKGAIDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVA
HKLPFAAKAVSRGTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGK
YWGKFYMPKRV
Target Bioclass
Other
Family
ABITRAM family
Subcellular location
Nucleus speckle
Function Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons.
Uniprot ID
Q9NX38
Ensemble ID
ENST00000322940.11
HGNC ID
HGNC:1364

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C74(1.10)  LDD0078  [1]
IA-alkyne
 Probe Info  		C46(0.00); C74(0.00)  LDD0167  [2]
IPM
 Probe Info  		N.A.  LDD0025  [3]
NAIA_5
 Probe Info  		C99(0.00); C46(0.00)  LDD2223  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C74(0.82)  LDD0812  [1]
 LDCM0215  AC10 HCT 116 C74(1.16)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C33(1.18); C37(1.18)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C33(0.97); C37(0.97)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C33(1.01); C37(1.01)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C33(1.00); C37(1.00)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C33(1.06); C37(1.06)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C33(1.07); C37(1.07)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C33(0.76); C37(0.76)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C33(0.85); C37(0.85)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C33(0.82); C37(0.82)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C33(1.02); C37(1.02)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C74(1.12)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C33(0.87); C37(0.87)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C33(0.91); C37(0.91)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C33(0.93); C37(0.93)  LDD0546  [1]
 LDCM0237  AC12 HCT 116 C74(0.94)  LDD0554  [1]
 LDCM0246  AC128 HEK-293T C74(1.06)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C74(1.09)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C74(1.17)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C74(1.24)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C74(1.20)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C74(1.62)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C74(1.12)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C74(1.02)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C74(1.00)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C74(1.20)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C74(1.05)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C74(0.80)  LDD0856  [1]
 LDCM0259  AC14 HCT 116 C74(1.12)  LDD0576  [1]
 LDCM0260  AC140 HEK-293T C74(1.26)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C74(1.38)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C74(1.31)  LDD0860  [1]
 LDCM0263  AC143 HCT 116 C33(0.73); C37(0.73)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C33(1.06); C37(1.06)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C33(0.74); C37(0.74)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C33(0.91); C37(0.91)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C33(1.01); C37(1.01)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C33(1.01); C37(1.01)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C33(0.75); C37(0.75)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C74(1.49)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C33(0.83); C37(0.83)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C33(0.75); C37(0.75)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C33(0.89); C37(0.89)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C33(1.05); C37(1.05)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C33(0.82); C37(0.82)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C33(0.64); C37(0.64)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C33(0.84); C37(0.84)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C33(1.10); C37(1.10)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C74(0.91)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C74(2.29)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C74(0.91)  LDD0595  [1]
 LDCM0279  AC2 HEK-293T C74(1.16)  LDD0877  [1]
 LDCM0280  AC20 HCT 116 C74(0.97)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C74(1.17)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C74(1.01)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C74(1.04)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C74(0.89)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C74(0.90)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C74(0.72)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C74(1.14)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C74(1.17)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C74(0.96)  LDD0606  [1]
 LDCM0290  AC3 HEK-293T C74(0.84)  LDD0888  [1]
 LDCM0291  AC30 HCT 116 C74(1.07)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C74(0.96)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C74(1.92)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C74(1.09)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C74(1.41)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C74(1.04)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C74(0.97)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C74(0.84)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C74(1.26)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C74(1.08)  LDD0617  [1]
 LDCM0301  AC4 HEK-293T C74(1.00)  LDD0899  [1]
 LDCM0302  AC40 HCT 116 C74(1.27)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C74(1.00)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C74(0.96)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C74(1.43)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C74(0.98)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C74(0.76)  LDD0624  [1]
 LDCM0308  AC46 PaTu 8988t C74(0.91)  LDD1187  [1]
 LDCM0309  AC47 PaTu 8988t C74(0.98)  LDD1188  [1]
 LDCM0310  AC48 PaTu 8988t C74(1.38)  LDD1189  [1]
 LDCM0311  AC49 PaTu 8988t C74(1.10)  LDD1190  [1]
 LDCM0312  AC5 HEK-293T C74(1.07)  LDD0910  [1]
 LDCM0313  AC50 PaTu 8988t C74(1.17)  LDD1192  [1]
 LDCM0314  AC51 PaTu 8988t C74(0.98)  LDD1193  [1]
 LDCM0315  AC52 PaTu 8988t C74(1.09)  LDD1194  [1]
 LDCM0316  AC53 PaTu 8988t C74(1.27)  LDD1195  [1]
 LDCM0317  AC54 PaTu 8988t C74(1.58)  LDD1196  [1]
 LDCM0318  AC55 PaTu 8988t C74(1.13)  LDD1197  [1]
 LDCM0319  AC56 PaTu 8988t C74(1.24)  LDD1198  [1]
 LDCM0320  AC57 HEK-293T C74(1.47)  LDD1559  [5]
 LDCM0321  AC58 HEK-293T C74(1.02)  LDD1560  [5]
 LDCM0322  AC59 HEK-293T C74(1.03)  LDD1561  [5]
 LDCM0323  AC6 HCT 116 C74(1.28)  LDD0640  [1]
 LDCM0324  AC60 HEK-293T C74(0.86)  LDD1563  [5]
 LDCM0325  AC61 HEK-293T C74(1.07)  LDD1564  [5]
 LDCM0326  AC62 HEK-293T C74(1.06)  LDD1565  [5]
 LDCM0327  AC63 HEK-293T C74(1.20)  LDD1566  [5]
 LDCM0328  AC64 HEK-293T C74(1.02)  LDD1567  [5]
 LDCM0332  AC68 HEK-293T C74(1.01)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C74(1.05)  LDD0931  [1]
 LDCM0334  AC7 HCT 116 C74(1.01)  LDD0651  [1]
 LDCM0335  AC70 HEK-293T C74(0.96)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C74(0.98)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C74(1.04)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C74(1.17)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C74(1.09)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C74(1.38)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C74(1.13)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C74(0.99)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C74(0.96)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C74(1.00)  LDD0942  [1]
 LDCM0345  AC8 HCT 116 C74(1.16)  LDD0662  [1]
 LDCM0346  AC80 HEK-293T C74(1.23)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C74(1.22)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C74(1.04)  LDD0946  [1]
 LDCM0349  AC83 HCT 116 C33(1.04); C37(1.04); C74(1.23)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C33(0.96); C37(0.96); C74(1.22)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C74(1.01); C33(1.03); C37(1.03)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C33(1.03); C37(1.03); C74(1.16)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C74(1.04); C33(1.18); C37(1.18)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C74(0.93); C33(1.27); C37(1.27)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C74(0.82); C33(1.04); C37(1.04)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C33(0.99); C37(0.99); C74(1.01)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C74(0.82); C33(1.25); C37(1.25)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C74(0.66); C33(1.06); C37(1.06)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C74(0.65); C33(0.92); C37(0.92)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C74(0.57); C33(1.13); C37(1.13)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C74(0.72); C33(1.23); C37(1.23)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C74(0.60); C33(1.12); C37(1.12)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C74(0.81); C33(1.13); C37(1.13)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C33(0.97); C37(0.97)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C33(0.88); C37(0.88)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C74(1.03)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C74(1.01)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C74(1.40)  LDD0592  [1]
 LDCM0020  ARS-1620 HCC44 C74(1.10)  LDD0078  [1]
 LDCM0367  CL1 HCT 116 C33(0.89); C37(0.89)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C33(0.86); C37(0.86)  LDD0685  [1]
 LDCM0369  CL100 HEK-293T C74(1.00)  LDD0967  [1]
 LDCM0370  CL101 HCT 116 C74(1.23)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C74(1.06)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C74(1.13)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C74(1.13)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C74(1.07)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C74(1.31)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C74(1.08)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C74(1.56)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C74(1.23)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C33(0.65); C37(0.65)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C74(1.85)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C74(1.32)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C74(1.31)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C74(1.42)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C74(1.43)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C74(1.11)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C74(1.02)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C74(1.44)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C74(1.33)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C74(1.14)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C33(0.84); C37(0.84)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C74(1.18)  LDD0708  [1]
 LDCM0392  CL121 PaTu 8988t C74(1.16)  LDD1271  [1]
 LDCM0393  CL122 PaTu 8988t C74(1.04)  LDD1272  [1]
 LDCM0394  CL123 PaTu 8988t C74(1.56)  LDD1273  [1]
 LDCM0395  CL124 PaTu 8988t C74(1.37)  LDD1274  [1]
 LDCM0396  CL125 HEK-293T C74(0.78)  LDD1600  [5]
 LDCM0398  CL127 HEK-293T C74(1.04); C99(1.70)  LDD1602  [5]
 LDCM0399  CL128 HEK-293T C74(1.12)  LDD1603  [5]
 LDCM0400  CL13 HCT 116 C33(0.69); C37(0.69)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C33(0.85); C37(0.85)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C33(0.84); C37(0.84)  LDD0719  [1]
 LDCM0403  CL16 HEK-293T C74(1.09)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C74(1.36)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C74(1.07)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C74(1.12)  LDD1004  [1]
 LDCM0407  CL2 HCT 116 C33(0.90); C37(0.90)  LDD0724  [1]
 LDCM0408  CL20 HEK-293T C74(1.29)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C74(1.37)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C74(1.31)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C74(0.94)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C74(1.21)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C74(1.22)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C74(1.08)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C74(1.20)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C74(1.15)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C74(1.15)  LDD1015  [1]
 LDCM0418  CL3 HCT 116 C33(0.94); C37(0.94)  LDD0735  [1]
 LDCM0419  CL30 HEK-293T C74(1.06)  LDD1017  [1]
 LDCM0420  CL31 PaTu 8988t C74(1.40)  LDD1299  [1]
 LDCM0421  CL32 PaTu 8988t C74(1.35)  LDD1300  [1]
 LDCM0422  CL33 PaTu 8988t C74(2.78)  LDD1301  [1]
 LDCM0423  CL34 PaTu 8988t C74(1.63)  LDD1302  [1]
 LDCM0424  CL35 PaTu 8988t C74(1.79)  LDD1303  [1]
 LDCM0425  CL36 PaTu 8988t C74(1.30)  LDD1304  [1]
 LDCM0426  CL37 PaTu 8988t C74(1.91)  LDD1305  [1]
 LDCM0428  CL39 PaTu 8988t C74(2.42)  LDD1307  [1]
 LDCM0429  CL4 HCT 116 C33(0.68); C37(0.68)  LDD0746  [1]
 LDCM0430  CL40 PaTu 8988t C74(1.56)  LDD1309  [1]
 LDCM0431  CL41 PaTu 8988t C74(1.94)  LDD1310  [1]
 LDCM0432  CL42 PaTu 8988t C74(1.65)  LDD1311  [1]
 LDCM0433  CL43 PaTu 8988t C74(2.33)  LDD1312  [1]
 LDCM0434  CL44 PaTu 8988t C74(2.03)  LDD1313  [1]
 LDCM0435  CL45 PaTu 8988t C74(3.02)  LDD1314  [1]
 LDCM0436  CL46 HCT 116 C74(1.19)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C74(1.07)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C74(0.99)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C74(1.15)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C33(0.77); C37(0.77)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C74(1.22)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C74(1.31)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C74(1.24)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C74(1.21)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C74(1.21)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C74(1.01)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C74(1.14)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C74(1.26)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C74(1.20)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C74(1.05)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C33(0.92); C37(0.92)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C74(1.20)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C74(0.80)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C74(0.78)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C74(1.20)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C74(1.13)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C74(0.93)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C74(1.17)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C74(1.09)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C74(1.11)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C74(1.02)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C33(0.77); C37(0.77)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C74(1.26)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C74(1.05)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C74(0.90)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C74(1.00)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C74(1.17)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C74(1.09)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C74(1.01)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C74(1.13)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C74(0.88)  LDD0789  [1]
 LDCM0473  CL8 HCT 116 C33(1.03); C37(1.03)  LDD0790  [1]
 LDCM0474  CL80 HCT 116 C74(1.00)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C74(0.90)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C74(0.80)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C74(0.91)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C74(1.05)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C74(1.12)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C74(1.02)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C74(0.89)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C74(0.92)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C74(0.99)  LDD0800  [1]
 LDCM0484  CL9 HCT 116 C33(0.70); C37(0.70)  LDD0801  [1]
 LDCM0485  CL90 HCT 116 C74(1.44)  LDD0802  [1]
 LDCM0486  CL91 HEK-293T C74(1.16)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C74(1.20)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C74(1.04)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C74(1.33)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C74(1.50)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C74(1.09)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C74(1.45)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C74(1.04)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C74(1.11)  LDD1092  [1]
 LDCM0495  E2913 HEK-293T C74(0.98); C99(1.35)  LDD1698  [5]
 LDCM0625  F8 Ramos C74(1.52)  LDD2187  [6]
 LDCM0572  Fragment10 Ramos C74(1.19)  LDD2189  [6]
 LDCM0573  Fragment11 Ramos C74(0.41)  LDD2190  [6]
 LDCM0574  Fragment12 Ramos C74(0.93)  LDD2191  [6]
 LDCM0575  Fragment13 Ramos C74(1.13)  LDD2192  [6]
 LDCM0576  Fragment14 Ramos C74(0.78)  LDD2193  [6]
 LDCM0579  Fragment20 Ramos C74(0.68)  LDD2194  [6]
 LDCM0580  Fragment21 Ramos C74(0.75)  LDD2195  [6]
 LDCM0582  Fragment23 Ramos C74(0.81)  LDD2196  [6]
 LDCM0578  Fragment27 Ramos C74(1.10)  LDD2197  [6]
 LDCM0586  Fragment28 Ramos C74(5.59)  LDD2198  [6]
 LDCM0588  Fragment30 Ramos C74(1.07)  LDD2199  [6]
 LDCM0589  Fragment31 Ramos C74(0.69)  LDD2200  [6]
 LDCM0590  Fragment32 Ramos C74(1.59)  LDD2201  [6]
 LDCM0468  Fragment33 HCT 116 C74(1.27)  LDD0785  [1]
 LDCM0596  Fragment38 Ramos C74(0.45)  LDD2203  [6]
 LDCM0566  Fragment4 Ramos C74(0.60)  LDD2184  [6]
 LDCM0427  Fragment51 PaTu 8988t C74(1.75)  LDD1306  [1]
 LDCM0614  Fragment56 Ramos C74(1.14)  LDD2205  [6]
 LDCM0569  Fragment7 Ramos C74(0.72)  LDD2186  [6]
 LDCM0571  Fragment9 Ramos C74(0.99)  LDD2188  [6]
 LDCM0022  KB02 HCT 116 C74(1.81)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C74(1.28)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C74(1.61)  LDD0082  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
tRNA pseudouridine synthase Pus10 (PUS10) Pseudouridine synthase Pus10 family Q3MIT2
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox-containing protein 1 (HMBOX1) . Q6NT76
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
LRP chaperone MESD (MESD) MESD family Q14696
Uncharacterized protein C4orf19 (C4orf19) . Q8IY42

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
6 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578