Details of the Target

General Information of Target

Target ID LDTP14434
Target Name Putative transcription factor Ovo-like 1 (OVOL1)
Gene Name OVOL1
Gene ID 5017
Synonyms
Putative transcription factor Ovo-like 1; hOvo1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPT
NAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVA
VDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGATCTINWR
KNDRSFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQIDVTK
MSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKK
FRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
Uniprot ID
O14753
Ensemble ID
ENST00000335987.8
HGNC ID
HGNC:8525

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C11(1.16); C15(1.16)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C11(1.16); C15(1.16)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C11(0.92); C15(0.92)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C11(0.89); C15(0.89)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C11(0.78); C15(0.78)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C11(0.76); C15(0.76)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C11(1.12); C15(1.12)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C11(1.02); C15(1.02)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C11(0.99); C15(0.99)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C11(1.01); C15(1.01)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C11(0.57); C15(0.95)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C11(0.73); C15(0.87)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C11(0.86); C15(0.87)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C11(0.84); C15(0.84)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C11(0.76); C15(0.88)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C11(0.86); C15(0.94)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C11(0.71); C15(0.98)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C11(1.09); C15(1.09)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C11(1.05); C15(1.05)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C11(1.16); C15(1.16)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C11(1.22); C15(1.22)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C11(1.05); C15(1.05)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C11(0.98); C15(0.98)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C11(1.34); C15(1.34)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C11(0.78); C15(0.78)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C11(1.00); C15(1.00)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C11(1.10); C15(1.10)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C11(1.28); C15(1.28)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C11(1.18); C15(1.18)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C11(1.17); C15(1.17)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C11(1.06); C15(1.06)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C11(1.40); C15(1.40)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C11(1.47); C15(1.47)  LDD0562  [1]
 LDCM0246  AC128 HCT 116 C11(1.06); C15(1.06)  LDD0563  [1]
 LDCM0247  AC129 HCT 116 C11(0.99); C15(0.99)  LDD0564  [1]
 LDCM0249  AC130 HCT 116 C11(1.26); C15(1.26)  LDD0566  [1]
 LDCM0250  AC131 HCT 116 C11(0.94); C15(0.94)  LDD0567  [1]
 LDCM0251  AC132 HCT 116 C11(0.94); C15(0.94)  LDD0568  [1]
 LDCM0252  AC133 HCT 116 C11(1.21); C15(1.21)  LDD0569  [1]
 LDCM0253  AC134 HCT 116 C11(1.34); C15(1.34)  LDD0570  [1]
 LDCM0254  AC135 HCT 116 C11(1.10); C15(1.10)  LDD0571  [1]
 LDCM0255  AC136 HCT 116 C11(1.17); C15(1.17)  LDD0572  [1]
 LDCM0256  AC137 HCT 116 C11(1.09); C15(1.09)  LDD0573  [1]
 LDCM0257  AC138 HCT 116 C11(0.83); C15(0.83)  LDD0574  [1]
 LDCM0258  AC139 HCT 116 C11(1.05); C15(1.05)  LDD0575  [1]
 LDCM0259  AC14 HCT 116 C11(0.85); C15(0.85)  LDD0576  [1]
 LDCM0260  AC140 HCT 116 C11(1.27); C15(1.27)  LDD0577  [1]
 LDCM0261  AC141 HCT 116 C11(1.00); C15(1.00)  LDD0578  [1]
 LDCM0262  AC142 HCT 116 C11(1.12); C15(1.12)  LDD0579  [1]
 LDCM0263  AC143 HCT 116 C11(1.22); C15(1.22)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C11(1.39); C15(1.39)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C11(1.13); C15(1.13)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C11(1.23); C15(1.23)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C11(1.15); C15(1.15)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C11(1.44); C15(1.44)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C11(1.34); C15(1.34)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C11(1.14); C15(1.14)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C11(1.13); C15(1.13)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C11(1.11); C15(1.11)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C11(1.29); C15(1.29)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C11(1.58); C15(1.58)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C11(1.19); C15(1.19)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C11(1.63); C15(1.63)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C11(1.37); C15(1.37)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C11(1.30); C15(1.30)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C11(1.28); C15(1.28)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C11(0.99); C15(0.99)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C11(1.36); C15(1.36)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C11(1.16); C15(1.16)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C11(1.35); C15(1.35)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C11(1.12); C15(1.12)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C11(1.25); C15(1.25)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C11(0.92); C15(0.92)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C11(1.26); C15(1.26)  LDD0601  [1]
 LDCM0290  AC3 HCT 116 C11(0.96); C15(0.96)  LDD0607  [1]
 LDCM0296  AC35 HCT 116 C11(1.67); C15(1.67)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C11(1.54); C15(1.54)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C11(1.78); C15(1.78)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C11(1.49); C15(1.49)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C11(1.78); C15(1.78)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C11(1.14); C15(1.14)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C11(2.11); C15(2.11)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C11(1.53); C15(1.53)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C11(1.60); C15(1.60)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C11(1.80); C15(1.80)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C11(1.82); C15(1.82)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C11(2.02); C15(2.02)  LDD0624  [1]
 LDCM0312  AC5 HCT 116 C11(1.21); C15(1.21)  LDD0629  [1]
 LDCM0320  AC57 HCT 116 C11(1.00); C15(1.00)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C11(1.15); C15(1.15)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C11(1.15); C15(1.15)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C11(1.21); C15(1.21)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C11(1.24); C15(1.24)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C11(1.11); C15(1.11)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C11(1.20); C15(1.20)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C11(1.47); C15(1.47)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C11(1.34); C15(1.34)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C11(1.16); C15(1.16)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C11(1.17); C15(1.17)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C11(1.34); C15(1.34)  LDD0648  [1]
 LDCM0334  AC7 HCT 116 C11(0.84); C15(0.84)  LDD0651  [1]
 LDCM0345  AC8 HCT 116 C11(0.82); C15(0.82)  LDD0662  [1]
 LDCM0349  AC83 HCT 116 C11(1.25); C15(1.25)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C11(1.26); C15(1.26)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C11(0.99); C15(0.99)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C11(1.17); C15(1.17)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C11(1.02); C15(1.02)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C11(1.19); C15(1.19)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C11(1.23); C15(1.23)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C11(1.04); C15(1.04)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C11(1.37); C15(1.37)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C11(1.44); C15(1.44)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C11(0.96); C15(0.96)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C11(1.07); C15(1.07)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C11(1.21); C15(1.21)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C11(1.32); C15(1.32)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C11(1.27); C15(1.27)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C11(1.10); C15(1.10)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C11(0.92); C15(0.92)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C11(0.83); C15(0.83)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C11(0.86); C15(0.86)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C11(1.22); C15(1.22)  LDD0592  [1]
 LDCM0369  CL100 HCT 116 C11(1.14); C15(1.14)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C11(1.17); C15(1.17)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C11(0.85); C15(0.85)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C11(1.22); C15(1.22)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C11(1.11); C15(1.11)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C11(1.37); C15(1.37)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C11(1.30); C15(1.30)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C11(1.06); C15(1.06)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C11(1.49); C15(1.49)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C11(1.17); C15(1.17)  LDD0695  [1]
 LDCM0380  CL110 HCT 116 C11(1.97); C15(1.97)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C11(1.37); C15(1.37)  LDD0698  [1]
 LDCM0387  CL117 HCT 116 C11(1.49); C15(1.49)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C11(1.34); C15(1.34)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C11(1.60); C15(1.60)  LDD0706  [1]
 LDCM0391  CL120 HCT 116 C11(1.67); C15(1.67)  LDD0708  [1]
 LDCM0396  CL125 HCT 116 C11(0.99); C15(0.99)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C11(0.80); C15(0.80)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C11(0.89); C15(0.89)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C11(1.06); C15(1.06)  LDD0716  [1]
 LDCM0403  CL16 HCT 116 C11(1.13); C15(1.13)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C11(0.99); C15(0.99)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C11(1.04); C15(1.04)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C11(0.96); C15(0.96)  LDD0723  [1]
 LDCM0408  CL20 HCT 116 C11(1.00); C15(1.00)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C11(1.11); C15(1.11)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C11(1.13); C15(1.13)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C11(0.98); C15(0.98)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C11(1.05); C15(1.05)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C11(1.13); C15(1.13)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C11(0.96); C15(0.96)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C11(0.98); C15(0.98)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C11(1.06); C15(1.06)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C11(0.98); C15(0.98)  LDD0734  [1]
 LDCM0419  CL30 HCT 116 C11(1.01); C15(1.01)  LDD0736  [1]
 LDCM0421  CL32 HCT 116 C11(0.90); C15(0.90)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C11(0.85); C15(0.85)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C11(0.83); C15(0.83)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C11(0.97); C15(0.97)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C11(0.63); C15(0.63)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C11(0.77); C15(0.77)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C11(0.91); C15(0.91)  LDD0745  [1]
 LDCM0430  CL40 HCT 116 C11(0.66); C15(0.66)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C11(0.75); C15(0.75)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C11(0.41); C15(0.41)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C11(0.76); C15(0.76)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C11(0.77); C15(0.77)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C11(0.69); C15(0.69)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C11(0.82); C15(0.82)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C11(0.85); C15(0.85)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C11(0.72); C15(0.72)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C11(0.70); C15(0.70)  LDD0756  [1]
 LDCM0441  CL50 HCT 116 C11(0.77); C15(0.77)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C11(0.70); C15(0.70)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C11(0.92); C15(0.92)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C11(0.79); C15(0.79)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C11(0.91); C15(0.91)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C11(0.65); C15(0.65)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C11(0.71); C15(0.71)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C11(0.56); C15(0.56)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C11(0.67); C15(0.67)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C11(0.56); C15(0.56)  LDD0767  [1]
 LDCM0452  CL60 HCT 116 C11(0.55); C15(0.55)  LDD0769  [1]
 LDCM0486  CL91 HCT 116 C11(1.06); C15(1.06)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C11(0.93); C15(0.93)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C11(0.96); C15(0.96)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C11(1.14); C15(1.14)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C11(1.18); C15(1.18)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C11(1.28); C15(1.28)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C11(1.07); C15(1.07)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C11(1.01); C15(1.01)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C11(1.19); C15(1.19)  LDD0811  [1]
 LDCM0427  Fragment51 HCT 116 C11(0.75); C15(0.75)  LDD0744  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Lamin-B2 (LMNB2) Intermediate filament family Q03252

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.