Details of the Target

General Information of Target

Target ID LDTP07094
Target Name Acyl-coenzyme A thioesterase THEM4 (THEM4)
Gene Name THEM4
Gene ID 117145
Synonyms
CTMP; Acyl-coenzyme A thioesterase THEM4; Acyl-CoA thioesterase THEM4; EC 3.1.2.2; Carboxyl-terminal modulator protein; Thioesterase superfamily member 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLRSCAARLRTLGALCLPPVGRRLPGSEPRPELRSFSSEEVILKDCSVPNPSWNKDLRLL
FDQFMKKCEDGSWKRLPSYKRTPTEWIQDFKTHFLDPKLMKEEQMSQAQLFTRSFDDGLG
FEYVMFYNDIEKRMVCLFQGGPYLEGPPGFIHGGAIATMIDATVGMCAMMAGGIVMTANL
NINYKRPIPLCSVVMINSQLDKVEGRKFFVSCNVQSVDEKTLYSEATSLFIKLNPAKSLT
Target Bioclass
Enzyme
Family
THEM4/THEM5 thioesterase family
Subcellular location
Cell membrane
Function
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According toinhibits AKT1 phosphorylation and activity. According toenhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
Uniprot ID
Q5T1C6
Ensemble ID
ENST00000368814.8
HGNC ID
HGNC:17947

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		14.23  LDD0403  [1]
DBIA
 Probe Info  		C46(1.10)  LDD0531  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [3]
AOyne
 Probe Info  		8.60  LDD0443  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C46(1.10)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C46(1.05)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C46(0.67)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C46(0.85)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C46(0.84)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C46(0.93)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C46(0.92)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C46(0.84)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C46(0.71)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C46(0.76)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C46(0.72)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C46(1.02)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C46(0.84)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C46(0.84)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C46(0.77)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C46(0.86)  LDD0546  [2]
 LDCM0237  AC12 HCT 116 C46(1.09)  LDD0554  [2]
 LDCM0259  AC14 HCT 116 C46(0.79)  LDD0576  [2]
 LDCM0270  AC15 HCT 116 C46(1.05)  LDD0587  [2]
 LDCM0276  AC17 HEK-293T C191(0.88); C46(0.87)  LDD1515  [5]
 LDCM0277  AC18 HEK-293T C191(0.80); C46(0.73)  LDD1516  [5]
 LDCM0278  AC19 HEK-293T C191(0.50); C46(1.14)  LDD1517  [5]
 LDCM0279  AC2 HCT 116 C46(1.03)  LDD0596  [2]
 LDCM0280  AC20 HEK-293T C191(0.91); C46(0.99)  LDD1519  [5]
 LDCM0281  AC21 HEK-293T C191(1.02); C46(0.67)  LDD1520  [5]
 LDCM0282  AC22 HEK-293T C191(1.03); C46(0.97)  LDD1521  [5]
 LDCM0283  AC23 HEK-293T C191(0.83); C46(0.90)  LDD1522  [5]
 LDCM0284  AC24 HEK-293T C46(1.00)  LDD1523  [5]
 LDCM0285  AC25 HCT 116 C46(0.99)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C46(0.87)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C46(0.85)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C46(0.93)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C46(0.84)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C46(1.06)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C46(0.83)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C46(0.97)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C46(0.79)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C46(0.83)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C46(0.90)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C46(1.01)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C46(0.87)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C46(0.84)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C46(1.03)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C46(1.19)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C46(1.11)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C46(0.95)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C46(0.71)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C46(0.93)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C46(0.79)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C46(0.95)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C46(0.84)  LDD0624  [2]
 LDCM0308  AC46 HEK-293T C191(1.02); C46(1.26)  LDD1547  [5]
 LDCM0309  AC47 HEK-293T C191(0.92); C46(1.02)  LDD1548  [5]
 LDCM0310  AC48 HEK-293T C46(1.02)  LDD1549  [5]
 LDCM0311  AC49 HEK-293T C191(0.98); C46(0.78)  LDD1550  [5]
 LDCM0312  AC5 HCT 116 C46(1.09)  LDD0629  [2]
 LDCM0313  AC50 HEK-293T C191(0.84); C46(0.93)  LDD1552  [5]
 LDCM0314  AC51 HEK-293T C191(0.76); C46(1.08)  LDD1553  [5]
 LDCM0315  AC52 HEK-293T C191(0.98); C46(1.18)  LDD1554  [5]
 LDCM0316  AC53 HEK-293T C191(0.87); C46(0.84)  LDD1555  [5]
 LDCM0317  AC54 HEK-293T C191(1.17); C46(0.96)  LDD1556  [5]
 LDCM0318  AC55 HEK-293T C191(0.92); C46(1.10)  LDD1557  [5]
 LDCM0319  AC56 HEK-293T C46(1.28)  LDD1558  [5]
 LDCM0320  AC57 HEK-293T C191(0.84); C46(0.70)  LDD1559  [5]
 LDCM0321  AC58 HEK-293T C191(1.02); C46(1.05)  LDD1560  [5]
 LDCM0322  AC59 HEK-293T C191(0.88); C46(0.79)  LDD1561  [5]
 LDCM0323  AC6 HCT 116 C46(0.95)  LDD0640  [2]
 LDCM0324  AC60 HEK-293T C191(0.92); C46(0.87)  LDD1563  [5]
 LDCM0325  AC61 HEK-293T C191(1.03); C46(0.79)  LDD1564  [5]
 LDCM0326  AC62 HEK-293T C191(0.98); C46(0.99)  LDD1565  [5]
 LDCM0327  AC63 HEK-293T C191(0.91); C46(1.02)  LDD1566  [5]
 LDCM0328  AC64 HEK-293T C46(0.95)  LDD1567  [5]
 LDCM0332  AC68 HCT 116 C46(1.16)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C46(1.26)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C46(0.92)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C46(0.94)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C46(1.34)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C46(0.95)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C46(1.20)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C46(1.38)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C46(1.05)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C46(1.14)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C46(1.05)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C46(0.91)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C46(1.26)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C46(0.81)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C46(0.96)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C46(1.24)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C46(1.08)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C46(1.07)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C46(1.16)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C46(1.15)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C46(1.02)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C46(1.12)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C46(1.12)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C46(1.08)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C46(0.96)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C46(1.25)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C46(1.19)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C46(1.14)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C46(1.59)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C46(1.14)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C46(1.24)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C46(1.04)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C46(0.81)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C46(0.84)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C46(1.06)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C46(0.74)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C46(0.96)  LDD0592  [2]
 LDCM0156  Aniline NCI-H1299 14.23  LDD0403  [1]
 LDCM0367  CL1 HCT 116 C46(1.05)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C46(1.02)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C46(1.04)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C46(0.98)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C46(1.13)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C46(0.94)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C46(1.04)  LDD0690  [2]
 LDCM0375  CL106 HEK-293T C191(0.93); C46(0.97)  LDD1579  [5]
 LDCM0376  CL107 HEK-293T C46(0.63)  LDD1580  [5]
 LDCM0377  CL108 HEK-293T C46(0.98)  LDD1581  [5]
 LDCM0379  CL11 HCT 116 C46(1.19)  LDD0696  [2]
 LDCM0380  CL110 HEK-293T C191(0.92); C46(1.03)  LDD1584  [5]
 LDCM0381  CL111 HEK-293T C46(0.91)  LDD1585  [5]
 LDCM0382  CL112 HCT 116 C46(0.89)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C46(0.76)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C46(0.86)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C46(0.80)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C46(1.03)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C46(1.07)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C46(0.81)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C46(0.78)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C46(1.11)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C46(0.72)  LDD0708  [2]
 LDCM0393  CL122 HEK-293T C191(0.93); C46(0.89)  LDD1597  [5]
 LDCM0394  CL123 HEK-293T C46(0.93)  LDD1598  [5]
 LDCM0395  CL124 HEK-293T C46(1.21)  LDD1599  [5]
 LDCM0397  CL126 HEK-293T C191(1.05); C46(0.99)  LDD1601  [5]
 LDCM0398  CL127 HEK-293T C46(0.80)  LDD1602  [5]
 LDCM0399  CL128 HEK-293T C46(1.07)  LDD1603  [5]
 LDCM0400  CL13 HCT 116 C46(1.16)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C46(0.97)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C46(1.13)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C46(0.88)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C46(1.26)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C46(1.01)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C46(1.00)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C46(1.12)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C46(1.02)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C46(1.25)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C46(1.03)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C46(0.86)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C46(0.90)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C46(0.72)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C46(0.84)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C46(1.02)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C46(0.78)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C46(0.90)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C46(0.86)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C46(0.96)  LDD0736  [2]
 LDCM0420  CL31 HEK-293T C191(0.57); C46(0.97)  LDD1624  [5]
 LDCM0421  CL32 HCT 116 C46(0.83)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C46(0.74)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C46(0.94)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C46(0.94)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C46(0.95)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C46(1.17)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C46(0.88)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C46(1.13)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C46(0.83)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C46(0.91)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C46(1.08)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C46(0.85)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C46(0.99)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C46(1.00)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C46(1.28)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C46(1.20)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C46(1.14)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C46(1.12)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C46(1.04)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C46(0.93)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C46(1.22)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C46(1.25)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C46(1.39)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C46(1.05)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C46(1.38)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C46(1.21)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C46(0.89)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C46(1.20)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C46(1.18)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C46(0.89)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C46(1.15)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C46(0.95)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C46(0.91)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C46(0.99)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C46(1.06)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C46(1.15)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C46(1.02)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C46(1.12)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C46(0.88)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C46(0.86)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C46(1.18)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C46(0.99)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C46(1.10)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C46(0.99)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C46(0.99)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C46(1.11)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C46(1.03)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C46(1.32)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C46(1.11)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C46(1.01)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C46(0.76)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C46(1.28)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C46(1.17)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C46(1.16)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C46(1.14)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C46(1.33)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C46(0.96)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C46(1.21)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C46(1.22)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C46(1.08)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C46(1.19)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C46(1.00)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C46(1.24)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C46(1.00)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C46(0.99)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C46(1.15)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C46(1.02)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C46(1.09)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C46(1.01)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C46(1.03)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C46(1.08)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C46(1.09)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C46(1.19)  LDD1698  [5]
 LDCM0468  Fragment33 HCT 116 C46(0.85)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C46(1.07)  LDD0744  [2]
 LDCM0022  KB02 HEK-293T C46(0.95)  LDD1492  [5]
 LDCM0023  KB03 HEK-293T C46(1.01)  LDD1497  [5]
 LDCM0024  KB05 MKN-1 C191(1.78)  LDD3331  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
RAC-alpha serine/threonine-protein kinase (AKT1) AGC Ser/Thr protein kinase family P31749
Fibroblast growth factor receptor 3 (FGFR3) Tyr protein kinase family P22607
GTPase HRas (HRAS) Ras family P01112
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Platelet endothelial cell adhesion molecule (PECAM1) . P16284
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Vimentin (VIM) Intermediate filament family P08670
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD044402
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840