Details of the Target

General Information of Target

Target ID LDTP06676
Target Name Centrosome and spindle pole-associated protein 1 (CSPP1)
Gene Name CSPP1
Gene ID 79848
Synonyms
CSPP; Centrosome and spindle pole-associated protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE
SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK
HKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERN
KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV
LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP
DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN
MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK
EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE
RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP
PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG
QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK
LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD
PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE
KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE
ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP
SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER
LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD
SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ
RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI
DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK
HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG
Target Bioclass
Other
Subcellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Function May play a role in cell-cycle-dependent microtubule organization.
Uniprot ID
Q1MSJ5
Ensemble ID
ENST00000519668.1
HGNC ID
HGNC:26193

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY-1
 Probe Info  		19.39  LDD0253  [1]
DBIA
 Probe Info  		C865(0.92)  LDD0533  [2]
IPM
 Probe Info  		N.A.  LDD2156  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C230(0.95); C400(0.90); C865(0.97)  LDD1507  [4]
 LDCM0215  AC10 HEK-293T C230(1.03); C865(1.00)  LDD1508  [4]
 LDCM0216  AC100 HCT 116 C865(0.92)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C865(0.89)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C865(1.08)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C865(1.32)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C865(1.26)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C865(1.05)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C865(1.17)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C865(0.57)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C865(0.70)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C865(0.71)  LDD0542  [2]
 LDCM0226  AC11 HEK-293T C230(1.00); C400(0.91); C865(1.06)  LDD1509  [4]
 LDCM0227  AC110 HCT 116 C865(0.65)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C865(0.68)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C865(0.63)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C865(0.84)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C865(1.00)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C865(1.25)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C865(1.14)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C865(1.15)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C865(0.92)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C865(1.01)  LDD0553  [2]
 LDCM0237  AC12 HEK-293T C400(1.19); C865(0.93)  LDD1510  [4]
 LDCM0238  AC120 HCT 116 C865(1.63)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C865(0.89)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C865(0.94)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C865(0.95)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C865(0.89)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C865(0.97)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C865(1.06)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C865(1.06)  LDD0562  [2]
 LDCM0259  AC14 HEK-293T C230(0.94); C865(0.93)  LDD1512  [4]
 LDCM0263  AC143 HCT 116 C865(0.97)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C865(1.19)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C865(1.15)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C865(1.34)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C865(1.32)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C865(2.01)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C865(1.39)  LDD0586  [2]
 LDCM0270  AC15 HEK-293T C230(0.99); C400(1.07); C865(1.04)  LDD1513  [4]
 LDCM0271  AC150 HCT 116 C865(1.04)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C865(1.18)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C865(1.37)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C865(2.88)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C865(1.50)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C865(1.47)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C865(0.92)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C865(0.91)  LDD2161  [2]
 LDCM0276  AC17 HEK-293T C230(1.09); C400(0.93); C865(0.99)  LDD1515  [4]
 LDCM0277  AC18 HEK-293T C230(1.03); C865(1.03)  LDD1516  [4]
 LDCM0278  AC19 HEK-293T C230(1.04); C400(1.35); C865(1.05)  LDD1517  [4]
 LDCM0279  AC2 HEK-293T C230(1.05); C865(1.07)  LDD1518  [4]
 LDCM0280  AC20 HEK-293T C400(0.91); C865(0.98)  LDD1519  [4]
 LDCM0281  AC21 HEK-293T C230(0.93); C400(1.13); C865(0.98)  LDD1520  [4]
 LDCM0282  AC22 HEK-293T C230(1.00); C865(1.01)  LDD1521  [4]
 LDCM0283  AC23 HEK-293T C230(0.96); C400(1.04); C865(1.03)  LDD1522  [4]
 LDCM0284  AC24 HEK-293T C230(0.95); C400(0.99); C865(0.93)  LDD1523  [4]
 LDCM0285  AC25 HEK-293T C230(0.99); C400(0.92); C865(0.97)  LDD1524  [4]
 LDCM0286  AC26 HEK-293T C230(1.04); C865(1.03)  LDD1525  [4]
 LDCM0287  AC27 HEK-293T C230(0.99); C400(0.88); C865(1.05)  LDD1526  [4]
 LDCM0288  AC28 HEK-293T C400(1.10); C865(0.93)  LDD1527  [4]
 LDCM0289  AC29 HEK-293T C230(0.81); C400(0.92); C865(0.96)  LDD1528  [4]
 LDCM0290  AC3 HEK-293T C230(1.02); C400(1.40); C865(1.03)  LDD1529  [4]
 LDCM0291  AC30 HEK-293T C230(1.01); C865(0.99)  LDD1530  [4]
 LDCM0292  AC31 HEK-293T C230(1.00); C400(0.93); C865(1.08)  LDD1531  [4]
 LDCM0293  AC32 HEK-293T C230(0.92); C400(1.10); C865(0.89)  LDD1532  [4]
 LDCM0294  AC33 HEK-293T C230(1.05); C400(0.92); C865(1.03)  LDD1533  [4]
 LDCM0295  AC34 HEK-293T C230(1.01); C865(1.06)  LDD1534  [4]
 LDCM0296  AC35 HEK-293T C230(1.07); C400(1.00); C865(1.09)  LDD1535  [4]
 LDCM0297  AC36 HEK-293T C400(1.17); C865(0.95)  LDD1536  [4]
 LDCM0298  AC37 HEK-293T C230(1.07); C400(0.96); C865(0.97)  LDD1537  [4]
 LDCM0299  AC38 HEK-293T C230(1.04); C865(0.92)  LDD1538  [4]
 LDCM0300  AC39 HEK-293T C230(1.01); C400(1.15); C865(1.10)  LDD1539  [4]
 LDCM0301  AC4 HEK-293T C400(1.41); C865(1.00)  LDD1540  [4]
 LDCM0302  AC40 HEK-293T C230(1.02); C400(0.96); C865(0.97)  LDD1541  [4]
 LDCM0303  AC41 HEK-293T C230(1.02); C400(0.93); C865(1.03)  LDD1542  [4]
 LDCM0304  AC42 HEK-293T C230(1.03); C865(1.00)  LDD1543  [4]
 LDCM0305  AC43 HEK-293T C230(1.04); C400(1.00); C865(1.05)  LDD1544  [4]
 LDCM0306  AC44 HEK-293T C400(1.36); C865(1.01)  LDD1545  [4]
 LDCM0307  AC45 HEK-293T C230(1.19); C400(0.96); C865(0.94)  LDD1546  [4]
 LDCM0308  AC46 HEK-293T C230(0.96); C865(1.03)  LDD1547  [4]
 LDCM0309  AC47 HEK-293T C230(1.05); C400(1.55); C865(1.06)  LDD1548  [4]
 LDCM0310  AC48 HEK-293T C230(1.07); C400(1.06); C865(0.98)  LDD1549  [4]
 LDCM0311  AC49 HEK-293T C230(0.97); C400(1.22); C865(1.00)  LDD1550  [4]
 LDCM0312  AC5 HEK-293T C230(1.10); C400(1.02); C865(0.98)  LDD1551  [4]
 LDCM0313  AC50 HEK-293T C230(1.08); C865(0.99)  LDD1552  [4]
 LDCM0314  AC51 HEK-293T C230(1.05); C400(1.64); C865(0.99)  LDD1553  [4]
 LDCM0315  AC52 HEK-293T C400(1.18); C865(1.05)  LDD1554  [4]
 LDCM0316  AC53 HEK-293T C230(0.96); C400(1.08); C865(1.01)  LDD1555  [4]
 LDCM0317  AC54 HEK-293T C230(1.09); C865(0.97)  LDD1556  [4]
 LDCM0318  AC55 HEK-293T C230(1.07); C400(1.23); C865(1.00)  LDD1557  [4]
 LDCM0319  AC56 HEK-293T C230(1.01); C400(1.07); C865(0.95)  LDD1558  [4]
 LDCM0320  AC57 HEK-293T C230(0.94); C400(0.97); C865(0.97)  LDD1559  [4]
 LDCM0321  AC58 HEK-293T C230(1.03); C865(1.16)  LDD1560  [4]
 LDCM0322  AC59 HEK-293T C230(0.95); C400(0.97); C865(1.08)  LDD1561  [4]
 LDCM0323  AC6 HEK-293T C230(1.10); C865(0.96)  LDD1562  [4]
 LDCM0324  AC60 HEK-293T C400(1.25); C865(0.98)  LDD1563  [4]
 LDCM0325  AC61 HEK-293T C230(1.00); C400(1.13); C865(0.96)  LDD1564  [4]
 LDCM0326  AC62 HEK-293T C230(0.97); C865(0.96)  LDD1565  [4]
 LDCM0327  AC63 HEK-293T C230(0.99); C400(1.15); C865(1.07)  LDD1566  [4]
 LDCM0328  AC64 HEK-293T C230(1.01); C400(1.02); C865(1.03)  LDD1567  [4]
 LDCM0334  AC7 HEK-293T C230(1.05); C400(1.15); C865(1.13)  LDD1568  [4]
 LDCM0345  AC8 HEK-293T C230(1.03); C400(1.14); C865(0.95)  LDD1569  [4]
 LDCM0365  AC98 HCT 116 C865(2.71)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C865(0.97)  LDD0683  [2]
 LDCM0248  AKOS034007472 HEK-293T C230(0.92); C400(1.11); C865(0.97)  LDD1511  [4]
 LDCM0356  AKOS034007680 HEK-293T C230(0.94); C400(0.83); C865(1.02)  LDD1570  [4]
 LDCM0275  AKOS034007705 HEK-293T C230(0.99); C400(1.23); C865(0.98)  LDD1514  [4]
 LDCM0020  ARS-1620 HCC44 C865(0.72)  LDD2171  [2]
 LDCM0367  CL1 HEK-293T C230(1.00); C400(1.17); C865(0.96)  LDD1571  [4]
 LDCM0368  CL10 HEK-293T C230(1.12); C865(0.96)  LDD1572  [4]
 LDCM0369  CL100 HEK-293T C230(0.93); C400(1.06); C865(0.92)  LDD1573  [4]
 LDCM0370  CL101 HEK-293T C230(1.06); C400(1.06); C865(1.15)  LDD1574  [4]
 LDCM0371  CL102 HEK-293T C230(0.94); C400(0.94); C865(1.05)  LDD1575  [4]
 LDCM0372  CL103 HEK-293T C230(1.00); C400(0.95); C865(0.91)  LDD1576  [4]
 LDCM0373  CL104 HEK-293T C230(0.92); C400(1.17); C865(0.96)  LDD1577  [4]
 LDCM0374  CL105 HEK-293T C230(1.02); C400(1.01); C865(1.05)  LDD1578  [4]
 LDCM0375  CL106 HEK-293T C230(0.94); C400(0.92); C865(1.09)  LDD1579  [4]
 LDCM0376  CL107 HEK-293T C230(1.04); C400(0.95); C865(0.98)  LDD1580  [4]
 LDCM0377  CL108 HEK-293T C230(0.90); C400(1.08); C865(1.03)  LDD1581  [4]
 LDCM0378  CL109 HEK-293T C230(0.91); C400(1.12); C865(0.87)  LDD1582  [4]
 LDCM0379  CL11 HEK-293T C230(1.22); C400(1.16); C865(0.88)  LDD1583  [4]
 LDCM0380  CL110 HEK-293T C230(0.94); C400(0.90); C865(0.97)  LDD1584  [4]
 LDCM0381  CL111 HEK-293T C230(0.86); C400(0.75); C865(0.95)  LDD1585  [4]
 LDCM0382  CL112 HEK-293T C230(0.91); C400(1.20); C865(1.07)  LDD1586  [4]
 LDCM0383  CL113 HEK-293T C230(1.03); C400(1.06); C865(1.02)  LDD1587  [4]
 LDCM0384  CL114 HEK-293T C230(1.02); C400(1.18); C865(1.03)  LDD1588  [4]
 LDCM0385  CL115 HEK-293T C230(1.01); C400(0.88); C865(0.93)  LDD1589  [4]
 LDCM0386  CL116 HEK-293T C230(1.01); C400(1.03); C865(1.07)  LDD1590  [4]
 LDCM0387  CL117 HEK-293T C230(1.10); C400(1.09); C865(0.99)  LDD1591  [4]
 LDCM0388  CL118 HEK-293T C230(1.15); C400(0.91); C865(1.18)  LDD1592  [4]
 LDCM0389  CL119 HEK-293T C230(1.03); C400(0.91); C865(0.90)  LDD1593  [4]
 LDCM0390  CL12 HEK-293T C230(1.17); C400(1.02); C865(0.92)  LDD1594  [4]
 LDCM0391  CL120 HEK-293T C230(0.90); C400(1.19); C865(1.02)  LDD1595  [4]
 LDCM0392  CL121 HEK-293T C230(1.06); C400(0.96); C865(0.99)  LDD1596  [4]
 LDCM0393  CL122 HEK-293T C230(1.00); C400(1.64); C865(1.08)  LDD1597  [4]
 LDCM0394  CL123 HEK-293T C230(0.88); C400(0.73); C865(0.93)  LDD1598  [4]
 LDCM0395  CL124 HEK-293T C230(0.88); C400(1.03); C865(0.97)  LDD1599  [4]
 LDCM0396  CL125 HEK-293T C230(0.94); C400(1.13); C865(1.07)  LDD1600  [4]
 LDCM0397  CL126 HEK-293T C230(0.97); C400(0.91); C865(1.06)  LDD1601  [4]
 LDCM0398  CL127 HEK-293T C230(1.01); C400(0.98); C865(0.92)  LDD1602  [4]
 LDCM0399  CL128 HEK-293T C230(0.89); C400(1.25); C865(1.01)  LDD1603  [4]
 LDCM0400  CL13 HEK-293T C230(1.00); C400(1.21); C865(1.05)  LDD1604  [4]
 LDCM0401  CL14 HEK-293T C230(1.10); C400(0.97); C865(1.07)  LDD1605  [4]
 LDCM0402  CL15 HEK-293T C230(0.95); C400(0.99); C865(0.83)  LDD1606  [4]
 LDCM0403  CL16 HEK-293T C230(0.94); C400(1.03); C865(1.04)  LDD1607  [4]
 LDCM0404  CL17 HEK-293T C230(1.00); C400(0.98); C865(0.83)  LDD1608  [4]
 LDCM0405  CL18 HEK-293T C230(1.09); C865(1.07)  LDD1609  [4]
 LDCM0406  CL19 HEK-293T C230(1.06); C400(0.85); C865(1.02)  LDD1610  [4]
 LDCM0407  CL2 HEK-293T C230(1.26); C400(1.12); C865(1.12)  LDD1611  [4]
 LDCM0408  CL20 HEK-293T C400(1.37); C865(0.88)  LDD1612  [4]
 LDCM0409  CL21 HEK-293T C230(1.12); C400(1.07); C865(0.87)  LDD1613  [4]
 LDCM0410  CL22 HEK-293T C230(1.24); C865(0.93)  LDD1614  [4]
 LDCM0411  CL23 HEK-293T C230(1.20); C400(1.09); C865(0.92)  LDD1615  [4]
 LDCM0412  CL24 HEK-293T C230(1.12); C400(1.46); C865(0.93)  LDD1616  [4]
 LDCM0413  CL25 HEK-293T C230(1.05); C400(0.81); C865(1.11)  LDD1617  [4]
 LDCM0414  CL26 HEK-293T C230(0.93); C400(0.99); C865(1.02)  LDD1618  [4]
 LDCM0415  CL27 HEK-293T C230(0.94); C400(1.28); C865(0.86)  LDD1619  [4]
 LDCM0416  CL28 HEK-293T C230(0.97); C400(1.08); C865(1.02)  LDD1620  [4]
 LDCM0417  CL29 HEK-293T C230(0.99); C400(0.91); C865(0.94)  LDD1621  [4]
 LDCM0418  CL3 HEK-293T C230(1.00); C400(0.93); C865(0.93)  LDD1622  [4]
 LDCM0419  CL30 HEK-293T C230(1.09); C865(0.99)  LDD1623  [4]
 LDCM0420  CL31 HCT 116 C865(1.63)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C865(0.81)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C865(1.16)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C865(1.11)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C865(1.11)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C865(1.55)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C865(0.95)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C865(1.03)  LDD0745  [2]
 LDCM0429  CL4 HEK-293T C230(0.93); C400(1.01); C865(0.98)  LDD1633  [4]
 LDCM0430  CL40 HCT 116 C865(1.88)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C865(0.86)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C865(0.96)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C865(0.91)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C865(0.89)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C865(1.71)  LDD0752  [2]
 LDCM0436  CL46 HEK-293T C230(1.18); C865(0.88)  LDD1640  [4]
 LDCM0437  CL47 HEK-293T C230(1.18); C400(1.25); C865(0.93)  LDD1641  [4]
 LDCM0438  CL48 HEK-293T C230(1.16); C400(1.09); C865(0.89)  LDD1642  [4]
 LDCM0439  CL49 HEK-293T C230(0.99); C400(1.19); C865(1.05)  LDD1643  [4]
 LDCM0440  CL5 HEK-293T C230(1.09); C400(1.10); C865(0.92)  LDD1644  [4]
 LDCM0441  CL50 HEK-293T C230(0.94); C400(0.98); C865(1.03)  LDD1645  [4]
 LDCM0443  CL52 HEK-293T C230(0.92); C400(1.27); C865(1.01)  LDD1646  [4]
 LDCM0444  CL53 HEK-293T C230(1.06); C400(0.86); C865(0.85)  LDD1647  [4]
 LDCM0445  CL54 HEK-293T C230(0.96); C865(0.92)  LDD1648  [4]
 LDCM0446  CL55 HEK-293T C230(1.22); C400(0.91); C865(0.91)  LDD1649  [4]
 LDCM0447  CL56 HEK-293T C400(0.92); C865(0.94)  LDD1650  [4]
 LDCM0448  CL57 HEK-293T C230(1.04); C400(1.00); C865(0.91)  LDD1651  [4]
 LDCM0449  CL58 HEK-293T C230(1.17); C865(0.90)  LDD1652  [4]
 LDCM0450  CL59 HEK-293T C230(1.16); C400(1.09); C865(0.96)  LDD1653  [4]
 LDCM0451  CL6 HEK-293T C230(1.06); C865(1.03)  LDD1654  [4]
 LDCM0452  CL60 HEK-293T C230(1.09); C400(1.02); C865(0.94)  LDD1655  [4]
 LDCM0453  CL61 HCT 116 C865(0.95)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C865(0.92)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C865(1.10)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C865(1.04)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C865(1.02)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C865(0.92)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C865(1.21)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C865(1.57)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C865(0.95)  LDD0778  [2]
 LDCM0462  CL7 HEK-293T C230(1.04); C400(0.88); C865(0.97)  LDD1665  [4]
 LDCM0463  CL70 HCT 116 C865(1.10)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C865(1.07)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C865(1.08)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C865(1.18)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C865(1.02)  LDD0784  [2]
 LDCM0469  CL76 HEK-293T C230(0.96); C400(0.99); C865(0.94)  LDD1672  [4]
 LDCM0470  CL77 HEK-293T C230(0.97); C400(0.95); C865(0.92)  LDD1673  [4]
 LDCM0471  CL78 HEK-293T C230(1.02); C865(1.06)  LDD1674  [4]
 LDCM0472  CL79 HEK-293T C230(1.00); C400(0.87); C865(1.01)  LDD1675  [4]
 LDCM0473  CL8 HEK-293T C400(1.00); C865(0.80)  LDD1676  [4]
 LDCM0474  CL80 HEK-293T C400(0.85); C865(1.05)  LDD1677  [4]
 LDCM0475  CL81 HEK-293T C230(1.10); C400(0.95); C865(0.97)  LDD1678  [4]
 LDCM0476  CL82 HEK-293T C230(1.16); C865(0.88)  LDD1679  [4]
 LDCM0477  CL83 HEK-293T C230(1.08); C400(1.25); C865(0.92)  LDD1680  [4]
 LDCM0478  CL84 HEK-293T C230(1.11); C400(0.73); C865(0.94)  LDD1681  [4]
 LDCM0479  CL85 HEK-293T C230(1.00); C400(1.03); C865(1.03)  LDD1682  [4]
 LDCM0480  CL86 HEK-293T C230(0.94); C400(0.74); C865(1.14)  LDD1683  [4]
 LDCM0481  CL87 HEK-293T C230(0.95); C400(1.09); C865(0.98)  LDD1684  [4]
 LDCM0482  CL88 HEK-293T C230(0.91); C400(1.17); C865(1.01)  LDD1685  [4]
 LDCM0483  CL89 HEK-293T C230(0.89); C400(0.87); C865(1.06)  LDD1686  [4]
 LDCM0484  CL9 HEK-293T C230(1.01); C400(0.82); C865(0.96)  LDD1687  [4]
 LDCM0485  CL90 HEK-293T C230(0.94); C865(1.03)  LDD1688  [4]
 LDCM0486  CL91 HEK-293T C230(0.99); C400(0.92); C865(1.03)  LDD1689  [4]
 LDCM0487  CL92 HEK-293T C400(1.03); C865(1.01)  LDD1690  [4]
 LDCM0488  CL93 HEK-293T C230(1.05); C400(1.00); C865(0.94)  LDD1691  [4]
 LDCM0489  CL94 HEK-293T C230(1.13); C865(1.05)  LDD1692  [4]
 LDCM0490  CL95 HEK-293T C230(0.97); C400(1.03); C865(0.88)  LDD1693  [4]
 LDCM0491  CL96 HEK-293T C230(0.99); C400(1.20); C865(0.93)  LDD1694  [4]
 LDCM0492  CL97 HEK-293T C230(1.10); C400(0.90); C865(0.91)  LDD1695  [4]
 LDCM0493  CL98 HEK-293T C230(0.98); C400(0.70); C865(1.05)  LDD1696  [4]
 LDCM0494  CL99 HEK-293T C230(1.05); C400(0.87); C865(0.91)  LDD1697  [4]
 LDCM0093  CY-5 Bcap37 19.39  LDD0253  [1]
 LDCM0495  E2913 HEK-293T C230(1.04); C400(1.12); C865(0.97)  LDD1698  [4]
 LDCM0468  Fragment33 HCT 116 C865(0.96)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C865(2.29)  LDD0744  [2]
 LDCM0022  KB02 HEK-293T C400(0.86); C865(1.04); C230(1.05)  LDD1492  [4]
 LDCM0023  KB03 HEK-293T C400(1.16); C865(1.00); C230(1.17)  LDD1497  [4]
 LDCM0024  KB05 OPM-2 C865(2.06)  LDD3377  [5]
 LDCM0021  THZ1 HCT 116 C865(0.72)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
MORF4 family-associated protein 1-like 1 (MRFAP1L1) MORF4 family-associated protein family Q96HT8
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
RAD50-interacting protein 1 (RINT1) RINT1 family Q6NUQ1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGRIP1) RPGRIP1 family Q96KN7

References

1 Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "Inverse Drug Discovery". J Med Chem. 2021 Nov 11;64(21):15582-15592. doi: 10.1021/acs.jmedchem.0c02024. Epub 2021 Oct 8.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
5 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840