General Information of Target

Target ID LDTP06663
Target Name Zinc finger protein 827 (ZNF827)
Gene Name ZNF827
Gene ID 152485
Synonyms
Zinc finger protein 827
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRRKQEQPKRLPSHVSRQEEAEGELSEGEHWYGNSSETPSEASYGEVQENYKLSLEDRI
QEQSTSPDTSLGSTTPSSHTLELVALDSEVLRDSLQCQDHLSPGVSSLCDDDPGSNKPLS
SNLRRLLEAGSLKLDAAATANGRVESPVNVGSNLSFSPPSHHAQQLSVLARKLAEKQEQN
DQYTPSNRFIWNQGKWLPNSTTTCSLSPDSAILKLKAAANAVLQDKSLTRTEETMRFESF
SSPFSSQSASSTLAALSKKVSERSLTPGQEHPPPASSFLSLASMTSSAALLKEVAARAAG
SLLAEKSSLLPEDPLPPPPSEKKPEKVTPPPPPPPPPPPPPPPQSLELLLLPVPKGRVSK
PSNSASEEESGKPFQCPICGLVIKRKSYWKRHMVIHTGLKSHQCPLCPFRCARKDNLKSH
MKVHQHQDRGETFQCQLCPFTSSRHFSLKLHMRCHQHFLRTEAKVKEEIPDPDVKGSPHL
SDSACLGQQREGGGTELVGTMMTSNTPERTSQGGAGVSPLLVKEEPKEDNGLPTSFTLNA
ADRPANHTKLKDPSEYVANSASALFSQDISVKMASDFLMKLSAANQKEPMNLNFKVKEEP
KEGESLSTTLPRSSYVFSPESEVSAPGVSEDALKPQEGKGSVLRRDVSVKAASELLMKLS
AESYKETQMVKIKEEPMEVDIQDSHVSISPSRNVGYSTLIGREKTEPLQKMPEGRVPPER
NLFSQDISVKMASELLFQLSEKVSKEHNHTKENTIRTTTSPFFSEDTFRQSPFTSNSKEL
LPSDSVLHGRISAPETEKIVLEAGNGLPSWKFNDQLFPCDVCGKVFGRQQTLSRHLSLHT
EERKYKCHLCPYAAKCRANLNQHLTVHSVKLVSTDTEDIVSAVTSEGSDGKKHPYYYSCH
VCGFETELNVQFVSHMSLHVDKEQWMFSICCTACDFVTMEEAEIKTHIGTKHTGEDRKTP
SESNSPSSSSLSALSDSANSKDDSDGSQKNKGGNNLLVISVMPGSQPSLNSEEKPEKGFE
CVFCNFVCKTKNMFERHLQIHLITRMFECDVCHKFMKTPEQLLEHKKCHTVPTGGLNSGQ
W
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function
As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation. Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance.
Uniprot ID
Q17R98
Ensemble ID
ENST00000379448.9
HGNC ID
HGNC:27193

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
769P SNV: p.V596L .
HCT15 SNV: p.G492Ter; p.K891N .
HEC1 SNV: p.Q1080Ter .
JHH1 SNV: p.E706K .
JHH7 SNV: p.D225V .
KMCH1 SNV: p.S157F .
KMS11 SNV: p.C1068Y .
MCC13 SNV: p.P208S .
MELJUSO SNV: p.S364L .
MOLT4 SNV: p.E713D .
NCIH196 SNV: p.S419C .
NCIH2172 SNV: p.Q63H .
PEO1 SNV: p.G104A .
REH SNV: p.R413L .
RL952 SNV: p.V869M .
SW1116 SNV: p.S684C .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C404(1.22); C407(1.22)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C404(1.22); C407(1.22)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C404(1.39); C407(1.39)  LDD0532  [1]
 LDCM0216  AC100 HCT 116 C404(0.92); C407(0.92)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C404(0.79); C407(0.79)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C404(0.99); C407(0.99)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C404(0.94); C407(0.94)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C404(0.86); C407(0.86)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C404(0.92); C407(0.92)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C404(1.00); C407(1.00)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C404(0.93); C407(0.93)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C404(0.90); C407(0.90)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C404(0.88); C407(0.88)  LDD0542  [1]
 LDCM0226  AC11 HCT 116 C404(1.33); C407(1.33)  LDD0543  [1]
 LDCM0227  AC110 HCT 116 C404(0.90); C407(0.90)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C404(0.83); C407(0.83)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C404(1.01); C407(1.01)  LDD0546  [1]
 LDCM0237  AC12 HCT 116 C404(1.16); C407(1.16)  LDD0554  [1]
 LDCM0259  AC14 HCT 116 C404(1.47); C407(1.47)  LDD0576  [1]
 LDCM0263  AC143 HCT 116 C404(0.93); C407(0.93)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C404(1.04); C407(1.04)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C404(0.91); C407(0.91)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C404(1.14); C407(1.14)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C404(1.07); C407(1.07)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C404(1.36); C407(1.36)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C404(1.05); C407(1.05)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C404(1.21); C407(1.21)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C404(1.11); C407(1.11)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C404(1.13); C407(1.13)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C404(0.96); C407(0.96)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C404(1.24); C407(1.24)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C404(1.05); C407(1.05)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C404(1.03); C407(1.03)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C404(0.98); C407(0.98)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C404(0.88); C407(0.88)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C404(0.80); C407(0.80)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C404(1.09); C407(1.09)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C404(1.02); C407(1.02)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C404(1.20); C407(1.20)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C404(1.02); C407(1.02)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C404(0.93); C407(0.93)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C404(1.04); C407(1.04)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C404(0.79); C407(0.79)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C404(1.17); C407(1.17)  LDD0601  [1]
 LDCM0285  AC25 HCT 116 C404(1.15); C407(1.15)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C404(1.22); C407(1.22)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C404(1.26); C407(1.26)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C404(1.10); C407(1.10)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C404(1.23); C407(1.23)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C404(1.32); C407(1.32)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C404(1.29); C407(1.29)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C404(1.35); C407(1.35)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C404(1.27); C407(1.27)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C404(1.16); C407(1.16)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C404(1.17); C407(1.17)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C404(0.82); C407(0.82)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C404(0.84); C407(0.84)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C404(0.92); C407(0.92)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C404(0.88); C407(0.88)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C404(0.83); C407(0.83)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C404(1.24); C407(1.24)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C404(0.83); C407(0.83)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C404(0.93); C407(0.93)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C404(0.82); C407(0.82)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C404(0.89); C407(0.89)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C404(1.04); C407(1.04)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C404(0.96); C407(0.96)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C404(0.97); C407(0.97)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C404(0.86); C407(0.86)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C404(1.26); C407(1.26)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C404(1.18); C407(1.18)  LDD0628  [1]
 LDCM0312  AC5 HCT 116 C404(1.30); C407(1.30)  LDD0629  [1]
 LDCM0313  AC50 HCT 116 C404(1.07); C407(1.07)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C404(1.03); C407(1.03)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C404(1.10); C407(1.10)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C404(0.97); C407(0.97)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C404(1.17); C407(1.17)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C404(1.27); C407(1.27)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C404(1.06); C407(1.06)  LDD0636  [1]
 LDCM0323  AC6 HCT 116 C404(1.22); C407(1.22)  LDD0640  [1]
 LDCM0332  AC68 HCT 116 C404(1.11); C407(1.11)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C404(1.05); C407(1.05)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C404(1.18); C407(1.18)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C404(1.10); C407(1.10)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C404(1.07); C407(1.07)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C404(1.03); C407(1.03)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C404(1.21); C407(1.21)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C404(1.33); C407(1.33)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C404(1.30); C407(1.30)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C404(1.10); C407(1.10)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C404(1.26); C407(1.26)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C404(0.96); C407(0.96)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C404(0.95); C407(0.95)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C404(1.18); C407(1.18)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C404(0.99); C407(0.99)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C404(0.77); C407(0.77)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C404(1.23); C407(1.23)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C404(1.12); C407(1.12)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C404(1.06); C407(1.06)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C404(0.97); C407(0.97)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C404(1.05); C407(1.05)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C404(0.97); C407(0.97)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C404(0.99); C407(0.99)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C404(1.32); C407(1.32)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C404(1.05); C407(1.05)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C404(1.13); C407(1.13)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C404(1.21); C407(1.21)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C404(0.91); C407(0.91)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C404(0.93); C407(0.93)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C404(1.07); C407(1.07)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C404(0.97); C407(0.97)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C404(1.10); C407(1.10)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C404(1.03); C407(1.03)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C404(0.95); C407(0.95)  LDD0683  [1]
 LDCM0248  AKOS034007472 HCT 116 C404(1.03); C407(1.03)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C404(1.15); C407(1.15)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C404(1.34); C407(1.34)  LDD0592  [1]
 LDCM0020  ARS-1620 HCC44 C847(1.60); C850(1.60)  LDD2171  [1]
 LDCM0369  CL100 HCT 116 C404(1.40); C407(1.40)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C404(1.45); C407(1.45)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C404(1.16); C407(1.16)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C404(0.99); C407(0.99)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C404(1.01); C407(1.01)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C404(1.01); C407(1.01)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C404(1.22); C407(1.22)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C404(1.15); C407(1.15)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C404(1.09); C407(1.09)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C404(0.86); C407(0.86)  LDD0695  [1]
 LDCM0380  CL110 HCT 116 C404(0.99); C407(0.99)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C404(0.74); C407(0.74)  LDD0698  [1]
 LDCM0382  CL112 HCT 116 C404(0.93); C407(0.93)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C404(1.03); C407(1.03)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C404(0.99); C407(0.99)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C404(1.11); C407(1.11)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C404(1.25); C407(1.25)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C404(0.85); C407(0.85)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C404(0.89); C407(0.89)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C404(0.88); C407(0.88)  LDD0706  [1]
 LDCM0391  CL120 HCT 116 C404(1.04); C407(1.04)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C404(2.52); C407(2.52)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C404(1.01); C407(1.01)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C404(0.76); C407(0.76)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C404(1.00); C407(1.00)  LDD0712  [1]
 LDCM0403  CL16 HCT 116 C404(1.17); C407(1.17)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C404(0.92); C407(0.92)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C404(1.08); C407(1.08)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C404(1.05); C407(1.05)  LDD0723  [1]
 LDCM0408  CL20 HCT 116 C404(1.14); C407(1.14)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C404(1.06); C407(1.06)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C404(0.99); C407(0.99)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C404(0.92); C407(0.92)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C404(1.11); C407(1.11)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C404(1.34); C407(1.34)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C404(1.08); C407(1.08)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C404(1.41); C407(1.41)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C404(1.18); C407(1.18)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C404(1.25); C407(1.25)  LDD0734  [1]
 LDCM0419  CL30 HCT 116 C404(1.37); C407(1.37)  LDD0736  [1]
 LDCM0420  CL31 HEK-293T C404(0.94); C407(0.94)  LDD1018  [1]
 LDCM0421  CL32 HCT 116 C404(1.16); C407(1.16)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C404(0.89); C407(0.89)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C404(0.92); C407(0.92)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C404(1.21); C407(1.21)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C404(0.93); C407(0.93)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C404(1.17); C407(1.17)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C404(1.01); C407(1.01)  LDD0745  [1]
 LDCM0430  CL40 HCT 116 C404(0.92); C407(0.92)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C404(0.94); C407(0.94)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C404(0.88); C407(0.88)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C404(1.12); C407(1.12)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C404(1.39); C407(1.39)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C404(1.31); C407(1.31)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C404(0.95); C407(0.95)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C404(0.97); C407(0.97)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C404(1.11); C407(1.11)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C404(1.22); C407(1.22)  LDD0756  [1]
 LDCM0441  CL50 HCT 116 C404(1.14); C407(1.14)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C404(1.28); C407(1.28)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C404(1.23); C407(1.23)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C404(1.09); C407(1.09)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C404(1.30); C407(1.30)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C404(1.18); C407(1.18)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C404(1.04); C407(1.04)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C404(1.20); C407(1.20)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C404(1.22); C407(1.22)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C404(1.23); C407(1.23)  LDD0767  [1]
 LDCM0452  CL60 HCT 116 C404(1.16); C407(1.16)  LDD0769  [1]
 LDCM0469  CL76 HCT 116 C404(0.70); C407(0.70)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C404(0.69); C407(0.69)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C404(0.84); C407(0.84)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C404(0.85); C407(0.85)  LDD0789  [1]
 LDCM0474  CL80 HCT 116 C404(0.91); C407(0.91)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C404(1.03); C407(1.03)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C404(0.84); C407(0.84)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C404(0.69); C407(0.69)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C404(0.90); C407(0.90)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C404(0.81); C407(0.81)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C404(0.77); C407(0.77)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C404(0.80); C407(0.80)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C404(0.71); C407(0.71)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C404(0.83); C407(0.83)  LDD0800  [1]
 LDCM0485  CL90 HCT 116 C404(0.73); C407(0.73)  LDD0802  [1]
 LDCM0486  CL91 HCT 116 C404(1.14); C407(1.14)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C404(0.95); C407(0.95)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C404(1.09); C407(1.09)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C404(1.45); C407(1.45)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C404(1.30); C407(1.30)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C404(1.35); C407(1.35)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C404(1.34); C407(1.34)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C404(1.13); C407(1.13)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C404(1.20); C407(1.20)  LDD0811  [1]
 LDCM0427  Fragment51 HCT 116 C404(1.03); C407(1.03)  LDD0744  [1]
 LDCM0021  THZ1 HCT 116 C847(1.60); C850(1.60)  LDD2173  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Histone deacetylase 2 (HDAC2) Histone deacetylase family Q92769
Chromodomain-helicase-DNA-binding protein 4 (CHD4) SNF2/RAD54 helicase family Q14839
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Metastasis-associated protein MTA2 (MTA2) . O94776
Transcriptional repressor p66-beta (GATAD2B) . Q8WXI9
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
LRP chaperone MESD (MESD) MESD family Q14696
Histone-binding protein RBBP7 (RBBP7) WD repeat RBAP46/RBAP48/MSI1 family Q16576

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.