Details of the Target

General Information of Target

Target ID LDTP01117
Target Name Protein CBFA2T3 (CBFA2T3)
Gene Name CBFA2T3
Gene ID 863
Synonyms
MTG16; MTGR2; ZMYND4; Protein CBFA2T3; MTG8-related protein 2; Myeloid translocation gene on chromosome 16 protein; hMTG16; Zinc finger MYND domain-containing protein 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGPAPVDRKAKAS
AMPDSPAEVKTQPRSTPPSMPPPPPAASQGATRPPSFTPHTHREDGPATLPHGRFHGCLK
WSMVCLLMNGSSHSPTAINGAPCTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRF
LTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANL
PLLQRELLHCARLAKQTPAQYLAQHEQLLLDASASSPIDSSELLLEVNENGKRRTPDRTK
ENGSDRDPLHPEHLSKRPCTLNPAQRYSPSNGPPQPTPPPHYRLEDIAMAHHFRDAYRHP
DPRELRERHRPLVVPGSRQEEVIDHKLTEREWAEEWKHLNNLLNCIMDMVEKTRRSLTVL
RRCQEADREELNHWARRYSDAEDTKKGPAPAAARPRSSSAGPEGPQLDVPREFLPRTLTG
YVPEDIWRKAEEAVNEVKRQAMSELQKAVSDAERKAHELITTERAKMERALAEAKRQASE
DALTVINQQEDSSESCWNCGRKASETCSGCNAARYCGSFCQHRDWEKHHHVCGQSLQGPT
AVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAGPSRPGSPSPPGPLDTVPR
Target Bioclass
Other
Family
CBFA2T family
Subcellular location
Nucleus, nucleolus; Nucleus, nucleoplasm
Function
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Reduces the protein levels and stability of the transcriptinal regulator HIF1A; interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway. Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the expression of glycolytic genes including PFKFB3, PFKFB4, PDK1, PFKP, LDHA and HK1 which are direct targets of HIF1A. Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. Plays a role in granulocyte differentiation.; Isoform 2 functions as an A-kinase-anchoring protein.
Uniprot ID
O75081
Ensemble ID
ENST00000268679.9
HGNC ID
HGNC:1537

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
BXPC3 SNV: p.E364Ter .
CCK81 SNV: p.G106R; p.L309P; p.P318S .
COLO792 SNV: p.V469L .
HCT15 SNV: p.E214K .
HGC27 SNV: p.P94L DBIA    Probe Info 
HSC3 SNV: p.T71R .
KMCH1 SNV: p.V545D .
KO52 SNV: p.W396Ter DBIA    Probe Info 
MOLT4 SNV: p.T201R; p.R368H; p.R415S IA-alkyne    Probe Info 
NALM6 SNV: p.G618S .
NCIH1993 SNV: p.P99S .
NCIH2291 SNV: p.G593C .
SJSA1 SNV: p.P77L .
SKMEL2 SNV: p.H359R .
SUPT1 SNV: p.G130D DBIA    Probe Info 
SW403 Deletion: p.R363GfsTer20 DBIA    Probe Info 
SW620 Substitution: p.S131P .
TOV21G SNV: p.P227H; p.E411Ter .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C250(1.06)  LDD0078  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [2]
NAIA_5
 Probe Info  		N.A.  LDD2224  [3]
TFBX
 Probe Info  		N.A.  LDD0148  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C250(1.15)  LDD0531  [1]
 LDCM0216  AC100 HCT 116 C250(1.12)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C250(1.07)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C250(1.06)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C250(1.47)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C250(1.28)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C250(1.20)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C250(1.28)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C250(1.57)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C250(0.98)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C250(0.85)  LDD0542  [1]
 LDCM0227  AC110 HCT 116 C250(0.93)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C250(0.89)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C250(1.11)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C250(1.08)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C250(1.33)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C250(1.68)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C250(1.49)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C250(1.34)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C250(1.45)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C250(1.48)  LDD0553  [1]
 LDCM0238  AC120 HCT 116 C250(1.55)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C250(1.25)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C250(1.31)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C250(1.16)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C250(1.23)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C250(1.25)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C250(1.52)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C250(1.50)  LDD0562  [1]
 LDCM0263  AC143 HCT 116 C250(1.20)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C250(1.70)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C250(1.37)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C250(1.70)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C250(1.82)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C250(2.63)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C250(1.90)  LDD0586  [1]
 LDCM0271  AC150 HCT 116 C250(1.29)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C250(1.11)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C250(1.87)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C250(2.45)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C250(1.52)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C250(1.51)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C250(1.23)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C250(1.17)  LDD2161  [1]
 LDCM0279  AC2 HCT 116 C250(1.19)  LDD0596  [1]
 LDCM0285  AC25 HCT 116 C250(1.05)  LDD0602  [1]
 LDCM0286  AC26 HCT 116 C250(1.21)  LDD0603  [1]
 LDCM0287  AC27 HCT 116 C250(1.18)  LDD0604  [1]
 LDCM0288  AC28 HCT 116 C250(1.20)  LDD0605  [1]
 LDCM0289  AC29 HCT 116 C250(1.30)  LDD0606  [1]
 LDCM0290  AC3 HCT 116 C250(1.26)  LDD0607  [1]
 LDCM0291  AC30 HCT 116 C250(1.25)  LDD0608  [1]
 LDCM0292  AC31 HCT 116 C250(1.21)  LDD0609  [1]
 LDCM0293  AC32 HCT 116 C250(1.38)  LDD0610  [1]
 LDCM0294  AC33 HCT 116 C250(1.37)  LDD0611  [1]
 LDCM0295  AC34 HCT 116 C250(1.45)  LDD0612  [1]
 LDCM0296  AC35 HCT 116 C250(0.91)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C250(1.07)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C250(0.91)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C250(1.24)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C250(1.18)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C250(1.52)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C250(1.05)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C250(1.18)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C250(1.06)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C250(1.08)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C250(0.89)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C250(0.74)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C250(0.98)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C250(0.89)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C250(0.87)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C250(1.18)  LDD0628  [1]
 LDCM0312  AC5 HCT 116 C250(1.45)  LDD0629  [1]
 LDCM0313  AC50 HCT 116 C250(0.89)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C250(0.92)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C250(1.00)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C250(0.85)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C250(0.84)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C250(1.24)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C250(1.03)  LDD0636  [1]
 LDCM0332  AC68 HCT 116 C250(1.20)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C250(1.22)  LDD0650  [1]
 LDCM0335  AC70 HCT 116 C250(1.30)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C250(1.17)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C250(1.27)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C250(1.82)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C250(1.80)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C250(2.00)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C250(1.28)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C250(1.31)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C250(1.08)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C250(1.39)  LDD0661  [1]
 LDCM0346  AC80 HCT 116 C250(1.24)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C250(1.08)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C250(1.97)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C250(1.85)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C250(1.93)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C250(1.62)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C250(1.34)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C250(1.01)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C250(1.12)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C250(1.28)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C250(0.92)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C250(1.96)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C250(1.67)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C250(1.39)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C250(1.08)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C250(1.04)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C250(1.54)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C250(1.44)  LDD0681  [1]
 LDCM0365  AC98 HCT 116 C250(1.85)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C250(0.94)  LDD0683  [1]
 LDCM0020  ARS-1620 HCC44 C250(1.06)  LDD0078  [1]
 LDCM0367  CL1 HCT 116 C250(0.95)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C250(1.09)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C250(1.31)  LDD0686  [1]
 LDCM0379  CL11 HCT 116 C250(1.10)  LDD0696  [1]
 LDCM0382  CL112 HCT 116 C250(1.08)  LDD0699  [1]
 LDCM0383  CL113 HCT 116 C250(1.35)  LDD0700  [1]
 LDCM0384  CL114 HCT 116 C250(1.19)  LDD0701  [1]
 LDCM0385  CL115 HCT 116 C250(1.24)  LDD0702  [1]
 LDCM0386  CL116 HCT 116 C250(1.27)  LDD0703  [1]
 LDCM0387  CL117 HCT 116 C250(1.14)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C250(1.08)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C250(1.03)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C250(1.24)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C250(1.21)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C250(1.06)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C250(0.87)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C250(1.00)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C250(0.94)  LDD0712  [1]
 LDCM0400  CL13 HCT 116 C250(1.10)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C250(1.01)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C250(1.15)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C250(0.93)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C250(1.00)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C250(1.04)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C250(1.07)  LDD0723  [1]
 LDCM0407  CL2 HCT 116 C250(0.88)  LDD0724  [1]
 LDCM0408  CL20 HCT 116 C250(1.18)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C250(1.40)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C250(1.72)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C250(1.17)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C250(1.29)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C250(1.33)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C250(1.17)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C250(1.09)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C250(1.13)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C250(1.36)  LDD0734  [1]
 LDCM0418  CL3 HCT 116 C250(0.87)  LDD0735  [1]
 LDCM0419  CL30 HCT 116 C250(1.00)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C250(0.86)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C250(1.01)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C250(0.92)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C250(0.83)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C250(0.86)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C250(0.95)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C250(1.00)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C250(0.99)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C250(0.97)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C250(0.97)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C250(0.82)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C250(0.81)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C250(0.85)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C250(0.88)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C250(0.90)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C250(1.13)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C250(1.03)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C250(1.23)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C250(1.05)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C250(1.09)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C250(1.08)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C250(1.16)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C250(1.15)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C250(1.22)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C250(1.23)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C250(1.12)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C250(1.11)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C250(1.11)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C250(1.13)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C250(1.13)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C250(1.09)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C250(1.16)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C250(1.09)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C250(1.02)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C250(0.88)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C250(1.07)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C250(1.00)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C250(0.97)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C250(0.92)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C250(0.99)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C250(1.11)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C250(1.27)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C250(1.04)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C250(0.97)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C250(1.20)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C250(1.06)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C250(0.98)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C250(0.97)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C250(0.89)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C250(0.88)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C250(0.94)  LDD0789  [1]
 LDCM0473  CL8 HCT 116 C250(1.26)  LDD0790  [1]
 LDCM0474  CL80 HCT 116 C250(0.95)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C250(0.94)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C250(0.83)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C250(0.86)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C250(1.02)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C250(0.94)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C250(0.92)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C250(1.05)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C250(0.87)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C250(0.89)  LDD0800  [1]
 LDCM0484  CL9 HCT 116 C250(1.21)  LDD0801  [1]
 LDCM0485  CL90 HCT 116 C250(1.06)  LDD0802  [1]
 LDCM0486  CL91 HCT 116 C250(0.96)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C250(1.10)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C250(1.04)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C250(1.10)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C250(1.36)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C250(1.13)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C250(1.22)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C250(1.34)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C250(1.45)  LDD0811  [1]
 LDCM0468  Fragment33 HCT 116 C250(1.13)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C250(0.84)  LDD0744  [1]
 LDCM0022  KB02 697 C250(1.66)  LDD2245  [5]
 LDCM0023  KB03 Jurkat C250(6.42)  LDD0209  [6]
 LDCM0024  KB05 MV4-11 C250(2.98)  LDD3338  [5]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 652 (ZNF652) Krueppel C2H2-type zinc-finger protein family Q9Y2D9
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Plexin-A3 (PLXNA3) Plexin family P51805

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
3 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
6 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.