General Information of Experiment

Probe Name C394  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 9 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01329  Lathosterol oxidase (SC5D) 13.3
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 8.9
 LDTP13751  Exonuclease 1 (EXO1) 8.1
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 7.4
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 6.9
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 6.7
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 6.5
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 6.3
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 6.1
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 21.7
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 7.0
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 6.2
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 5.5
Other
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 16.4
 LDTP05160  Nucleobindin-2 (NUCB2) 7.0
 LDTP13630  Neudesin (NENF) 6.8
 LDTP14058  Rap guanine nucleotide exchange factor 2 (RAPGEF2) 5.9
 LDTP05226  RNA-binding protein 3 (RBM3) 5.0

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587