Probe Name	C236					Probe Info
Probe concentration	Probe:50uM; negative probe:50uM
Criteria	Quantification: AfBPP Probe vs Negative Probe
Quantitative Method	TMT
In Vivo Experiment Model	Model Type			Living cell
	Derived Tissue			Peripheral blood
	Disease Model		Normal
	Model Name		Human normal cells (HEK-293T)
Note	Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Target ID	Target Name					Binding Ratio
LDTP15132	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3)					34.3
LDTP05758	S-methyl-5'-thioadenosine phosphorylase (MTAP)					24.3
LDTP06333	Serum paraoxonase/arylesterase 2 (PON2)					8.0
LDTP06227	Prostaglandin reductase 1 (PTGR1)					6.9
LDTP10101	Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10)					6.4
LDTP04581	Holocytochrome c-type synthase (HCCS)					6.0
LDTP10286	Corrinoid adenosyltransferase MMAB (MMAB)					5.5
LDTP12628	Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10)					5.5
LDTP12868	Endoplasmic reticulum aminopeptidase 1 (ERAP1)					5.2
LDTP00645	Prolyl 4-hydroxylase subunit alpha-2 (P4HA2)					5.2
LDTP11268	Acireductone dioxygenase (ADI1)					5.0
LDTP00575	Glutathione S-transferase A4 (GSTA4)					5.0

Target ID	Target Name					Binding Ratio
LDTP12078	Mitochondrial glutamate carrier 1 (SLC25A22)					9.7
LDTP18153	Major facilitator superfamily domain-containing protein 3 (MFSD3)					7.9
LDTP00865	Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20)					5.4

Target ID	Target Name					Binding Ratio
LDTP11076	Apolipoprotein L2 (APOL2)					11.6
LDTP15269	Large ribosomal subunit protein mL55 (MRPL55)					6.4
LDTP15623	Neuferricin (CYB5D2)					6.3
LDTP06391	Protein transport protein Sec23B (SEC23B)					6.2
LDTP08081	Hepatoma-derived growth factor-related protein 2 (HDGFL2)					5.4

1	Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Mass spectrometry data entry: PXD041587