General Information of Experiment

Probe Name C203  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 9 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 44.0
 LDTP02565  Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) 16.7
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 15.7
 LDTP13240  Poly [ADP-ribose] polymerase 2 (PARP2) 11.6
 LDTP12679  Trimethyllysine dioxygenase, mitochondrial (TMLHE) 10.6
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 9.8
 LDTP02375  Poly [ADP-ribose] polymerase 1 (PARP1) 8.8
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 5.1
 LDTP08265  N-alpha-acetyltransferase 40 (NAA40) 5.0
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 19.0
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 7.0
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 5.9
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 5.1
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01075  Protein CutA (CUTA) 12.2
 LDTP00887  Calumenin (CALU) 7.6
 LDTP13946  U6 snRNA-associated Sm-like protein LSm2 (LSM2) 7.5

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587