Details of the Target

General Information of Target

Target ID LDTP19319
Target Name Ankyrin repeat domain-containing protein SOWAHC (SOWAHC)
Gene Name SOWAHC
Gene ID 65124
Synonyms
ANKRD57; C2orf26; Ankyrin repeat domain-containing protein SOWAHC; Ankyrin repeat domain-containing protein 57; Protein sosondowah homolog C
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKSVISYALYQVQTGSLPVYSSVLTKSPLQLQTVIYRLIVQIQHLNIPSSSSTHSSPF
Target Bioclass
Other
Family
SOWAH family
Uniprot ID
Q53LP3
Ensemble ID
ENST00000356454.5
HGNC ID
HGNC:26149

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K57(8.68); K75(10.00)  LDD0277  [1]
m-APA
 Probe Info  		10.51  LDD0403  [2]
AHL-Pu-1
 Probe Info  		C289(2.30)  LDD0169  [3]
Acrolein
 Probe Info  		N.A.  LDD0222  [4]
DBIA
 Probe Info  		C84(1.47); C221(1.16)  LDD0078  [5]
IA-alkyne
 Probe Info  		C84(0.00); C221(0.00)  LDD0162  [6]
NAIA_4
 Probe Info  		C84(0.00); C221(0.00)  LDD2226  [7]
TFBX
 Probe Info  		N.A.  LDD0027  [8]
WYneN
 Probe Info  		N.A.  LDD0021  [9]
IPM
 Probe Info  		N.A.  LDD0005  [9]
Methacrolein
 Probe Info  		N.A.  LDD0218  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C289(2.14)  LDD0170  [3]
 LDCM0026  4SU-RNA+native RNA HEK-293T C289(2.30)  LDD0169  [3]
 LDCM0214  AC1 PaTu 8988t C84(0.82)  LDD1093  [5]
 LDCM0215  AC10 HCT 116 C84(2.03)  LDD0532  [5]
 LDCM0216  AC100 PaTu 8988t C84(1.25)  LDD1095  [5]
 LDCM0217  AC101 PaTu 8988t C84(1.35)  LDD1096  [5]
 LDCM0218  AC102 PaTu 8988t C84(1.28)  LDD1097  [5]
 LDCM0219  AC103 PaTu 8988t C84(1.34)  LDD1098  [5]
 LDCM0220  AC104 PaTu 8988t C84(1.39)  LDD1099  [5]
 LDCM0221  AC105 PaTu 8988t C84(1.61)  LDD1100  [5]
 LDCM0222  AC106 PaTu 8988t C84(1.61)  LDD1101  [5]
 LDCM0223  AC107 PaTu 8988t C84(1.60)  LDD1102  [5]
 LDCM0224  AC108 PaTu 8988t C84(1.18)  LDD1103  [5]
 LDCM0225  AC109 PaTu 8988t C84(1.77)  LDD1104  [5]
 LDCM0226  AC11 HCT 116 C84(1.56)  LDD0543  [5]
 LDCM0227  AC110 PaTu 8988t C84(1.29)  LDD1106  [5]
 LDCM0228  AC111 PaTu 8988t C84(2.33)  LDD1107  [5]
 LDCM0229  AC112 PaTu 8988t C84(1.22)  LDD1108  [5]
 LDCM0230  AC113 HCT 116 C84(0.91)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C84(1.35)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C84(1.36)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C84(1.48)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C84(1.16)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C84(1.11)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C84(1.36)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C84(1.28)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C84(1.38)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C84(1.06)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C84(1.97)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C84(1.28)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C84(1.32)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C84(2.27)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C84(1.24)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C84(1.92)  LDD0562  [5]
 LDCM0246  AC128 PaTu 8988t C84(1.92)  LDD1125  [5]
 LDCM0247  AC129 PaTu 8988t C84(1.50)  LDD1126  [5]
 LDCM0249  AC130 PaTu 8988t C84(1.65)  LDD1128  [5]
 LDCM0250  AC131 PaTu 8988t C84(1.20)  LDD1129  [5]
 LDCM0251  AC132 PaTu 8988t C84(1.05)  LDD1130  [5]
 LDCM0252  AC133 PaTu 8988t C84(1.22)  LDD1131  [5]
 LDCM0253  AC134 PaTu 8988t C84(1.18)  LDD1132  [5]
 LDCM0254  AC135 PaTu 8988t C84(1.73)  LDD1133  [5]
 LDCM0255  AC136 PaTu 8988t C84(1.41)  LDD1134  [5]
 LDCM0256  AC137 PaTu 8988t C84(1.16)  LDD1135  [5]
 LDCM0257  AC138 PaTu 8988t C84(1.35)  LDD1136  [5]
 LDCM0258  AC139 PaTu 8988t C84(1.67)  LDD1137  [5]
 LDCM0259  AC14 HCT 116 C84(1.91)  LDD0576  [5]
 LDCM0260  AC140 PaTu 8988t C84(1.51)  LDD1139  [5]
 LDCM0261  AC141 PaTu 8988t C84(1.38)  LDD1140  [5]
 LDCM0262  AC142 PaTu 8988t C84(1.19)  LDD1141  [5]
 LDCM0270  AC15 HCT 116 C84(2.31)  LDD0587  [5]
 LDCM0276  AC17 HCT 116 C84(1.50)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C84(1.26)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C84(1.54)  LDD0595  [5]
 LDCM0279  AC2 PaTu 8988t C84(0.62)  LDD1158  [5]
 LDCM0280  AC20 HCT 116 C84(1.33)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C84(1.46)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C84(1.17)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C84(1.62)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C84(1.30)  LDD0601  [5]
 LDCM0285  AC25 HCT 116 C84(1.00)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C84(1.17)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C84(1.35)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C84(1.22)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C84(1.37)  LDD0606  [5]
 LDCM0290  AC3 PaTu 8988t C84(0.67)  LDD1169  [5]
 LDCM0291  AC30 HCT 116 C84(1.23)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C84(1.27)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C84(1.57)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C84(1.41)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C84(1.53)  LDD0612  [5]
 LDCM0296  AC35 PaTu 8988t C84(1.19)  LDD1175  [5]
 LDCM0297  AC36 PaTu 8988t C84(1.58)  LDD1176  [5]
 LDCM0298  AC37 PaTu 8988t C84(1.28)  LDD1177  [5]
 LDCM0299  AC38 PaTu 8988t C84(1.30)  LDD1178  [5]
 LDCM0300  AC39 PaTu 8988t C84(1.39)  LDD1179  [5]
 LDCM0301  AC4 PaTu 8988t C84(0.74)  LDD1180  [5]
 LDCM0302  AC40 PaTu 8988t C84(1.30)  LDD1181  [5]
 LDCM0303  AC41 PaTu 8988t C84(1.17)  LDD1182  [5]
 LDCM0304  AC42 PaTu 8988t C84(1.24)  LDD1183  [5]
 LDCM0305  AC43 PaTu 8988t C84(1.27)  LDD1184  [5]
 LDCM0306  AC44 PaTu 8988t C84(1.21)  LDD1185  [5]
 LDCM0307  AC45 PaTu 8988t C84(1.14)  LDD1186  [5]
 LDCM0310  AC48 HEK-293T C289(0.89)  LDD1549  [10]
 LDCM0312  AC5 PaTu 8988t C84(0.88)  LDD1191  [5]
 LDCM0316  AC53 HEK-293T C289(1.32)  LDD1555  [10]
 LDCM0319  AC56 HEK-293T C289(0.91)  LDD1558  [10]
 LDCM0320  AC57 HCT 116 C84(2.43)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C84(2.42)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C84(2.68)  LDD0639  [5]
 LDCM0323  AC6 HCT 116 C84(2.01)  LDD0640  [5]
 LDCM0324  AC60 HCT 116 C84(2.21)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C84(1.93)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C84(2.16)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C84(2.14)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C84(2.59)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C84(3.01)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C84(2.50)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C84(2.84)  LDD0648  [5]
 LDCM0332  AC68 PaTu 8988t C84(0.67)  LDD1211  [5]
 LDCM0333  AC69 PaTu 8988t C84(1.11)  LDD1212  [5]
 LDCM0334  AC7 HCT 116 C84(2.29)  LDD0651  [5]
 LDCM0335  AC70 PaTu 8988t C84(0.85)  LDD1214  [5]
 LDCM0336  AC71 PaTu 8988t C84(0.65)  LDD1215  [5]
 LDCM0337  AC72 PaTu 8988t C84(0.59)  LDD1216  [5]
 LDCM0338  AC73 PaTu 8988t C84(0.75)  LDD1217  [5]
 LDCM0339  AC74 PaTu 8988t C84(0.58)  LDD1218  [5]
 LDCM0340  AC75 PaTu 8988t C84(0.73)  LDD1219  [5]
 LDCM0341  AC76 PaTu 8988t C84(0.95)  LDD1220  [5]
 LDCM0342  AC77 PaTu 8988t C84(0.90)  LDD1221  [5]
 LDCM0343  AC78 PaTu 8988t C84(0.67)  LDD1222  [5]
 LDCM0344  AC79 PaTu 8988t C84(1.03)  LDD1223  [5]
 LDCM0345  AC8 HCT 116 C84(1.33)  LDD0662  [5]
 LDCM0346  AC80 PaTu 8988t C84(0.72)  LDD1225  [5]
 LDCM0347  AC81 PaTu 8988t C84(0.82)  LDD1226  [5]
 LDCM0348  AC82 PaTu 8988t C84(0.63)  LDD1227  [5]
 LDCM0349  AC83 HCT 116 C84(1.82)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C84(1.51)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C84(1.34)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C84(1.12)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C84(0.87)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C84(1.56)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C84(1.62)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C84(1.26)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C84(3.06)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C84(1.58)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C84(1.17)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C84(1.13)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C84(1.54)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C84(1.21)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C84(1.39)  LDD0681  [5]
 LDCM0365  AC98 PaTu 8988t C84(1.65)  LDD1244  [5]
 LDCM0366  AC99 PaTu 8988t C84(1.65)  LDD1245  [5]
 LDCM0248  AKOS034007472 HCT 116 C84(1.18)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C84(1.49)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C84(2.70)  LDD0592  [5]
 LDCM0156  Aniline NCI-H1299 10.51  LDD0403  [2]
 LDCM0020  ARS-1620 HCC44 C84(1.47); C221(1.16)  LDD0078  [5]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [4]
 LDCM0367  CL1 HCT 116 C84(1.05)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C84(1.47)  LDD0685  [5]
 LDCM0369  CL100 PaTu 8988t C84(0.55)  LDD1248  [5]
 LDCM0370  CL101 HCT 116 C84(2.48)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C84(1.69)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C84(1.58)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C84(1.58)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C84(1.59)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C84(2.01)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C84(1.97)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C84(2.09)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C84(1.36)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C84(2.35)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C84(2.06)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C84(1.46)  LDD0698  [5]
 LDCM0382  CL112 HCT 116 C84(1.13)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C84(1.30)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C84(1.21)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C84(1.49)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C84(1.24)  LDD0703  [5]
 LDCM0387  CL117 PaTu 8988t C84(1.11)  LDD1266  [5]
 LDCM0388  CL118 PaTu 8988t C84(0.95)  LDD1267  [5]
 LDCM0389  CL119 PaTu 8988t C84(1.61)  LDD1268  [5]
 LDCM0390  CL12 HCT 116 C84(1.75)  LDD0707  [5]
 LDCM0391  CL120 PaTu 8988t C84(1.10)  LDD1270  [5]
 LDCM0392  CL121 HEK-293T C289(0.96)  LDD1596  [10]
 LDCM0393  CL122 HEK-293T C289(1.29)  LDD1597  [10]
 LDCM0394  CL123 HEK-293T C289(0.83)  LDD1598  [10]
 LDCM0395  CL124 HEK-293T C289(1.02)  LDD1599  [10]
 LDCM0396  CL125 HCT 116 C84(1.21)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C84(1.24)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C84(1.70)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C84(2.72)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C84(1.47)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C84(1.48)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C84(1.52)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C84(0.91)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C84(1.15)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C84(1.03)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C84(0.97)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C84(0.95)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C84(1.85)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C84(1.90)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C84(3.63)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C84(1.29)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C84(1.79)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C84(1.38)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C84(1.03)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C84(1.22)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C84(1.53)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C84(1.16)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C84(1.35)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C84(1.19)  LDD0736  [5]
 LDCM0422  CL33 HEK-293T C289(1.98)  LDD1626  [10]
 LDCM0425  CL36 HEK-293T C289(1.02)  LDD1629  [10]
 LDCM0426  CL37 HEK-293T C289(0.66)  LDD1630  [10]
 LDCM0428  CL39 HEK-293T C289(0.99)  LDD1632  [10]
 LDCM0429  CL4 HCT 116 C84(1.01)  LDD0746  [5]
 LDCM0430  CL40 HEK-293T C289(0.84)  LDD1634  [10]
 LDCM0435  CL45 HEK-293T C289(0.98)  LDD1639  [10]
 LDCM0436  CL46 HCT 116 C84(0.55)  LDD0753  [5]
 LDCM0437  CL47 HCT 116 C84(0.68)  LDD0754  [5]
 LDCM0438  CL48 HCT 116 C84(0.43)  LDD0755  [5]
 LDCM0439  CL49 HCT 116 C84(0.60)  LDD0756  [5]
 LDCM0440  CL5 HCT 116 C84(1.39)  LDD0757  [5]
 LDCM0441  CL50 HCT 116 C84(0.75)  LDD0758  [5]
 LDCM0442  CL51 HCT 116 C84(0.52)  LDD0759  [5]
 LDCM0443  CL52 HCT 116 C84(0.77)  LDD0760  [5]
 LDCM0444  CL53 HCT 116 C84(0.62)  LDD0761  [5]
 LDCM0445  CL54 HCT 116 C84(0.58)  LDD0762  [5]
 LDCM0446  CL55 HCT 116 C84(0.83)  LDD0763  [5]
 LDCM0447  CL56 HCT 116 C84(0.72)  LDD0764  [5]
 LDCM0448  CL57 HCT 116 C84(0.44)  LDD0765  [5]
 LDCM0449  CL58 HCT 116 C84(0.37)  LDD0766  [5]
 LDCM0450  CL59 HCT 116 C84(0.65)  LDD0767  [5]
 LDCM0451  CL6 HCT 116 C84(2.21)  LDD0768  [5]
 LDCM0452  CL60 HCT 116 C84(0.63)  LDD0769  [5]
 LDCM0453  CL61 HCT 116 C84(1.11)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C84(0.97)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C84(1.06)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C84(2.36)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C84(1.03)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C84(1.73)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C84(1.44)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C84(1.15)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C84(1.22)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C84(1.61)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C84(1.21)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C84(1.45)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C84(0.99)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C84(1.83)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C84(1.55)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C84(1.59)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C84(1.61)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C84(1.50)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C84(1.90)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C84(2.47)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C84(1.30)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C84(1.60)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C84(3.27)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C84(2.11)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C84(2.70)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C84(1.43)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C84(1.01)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C84(2.43)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C84(2.79)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C84(5.51)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C84(1.45)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C84(1.15)  LDD0802  [5]
 LDCM0486  CL91 PaTu 8988t C84(0.60)  LDD1365  [5]
 LDCM0487  CL92 PaTu 8988t C84(0.48)  LDD1366  [5]
 LDCM0488  CL93 PaTu 8988t C84(0.49)  LDD1367  [5]
 LDCM0489  CL94 PaTu 8988t C84(0.57)  LDD1368  [5]
 LDCM0490  CL95 PaTu 8988t C84(0.63)  LDD1369  [5]
 LDCM0491  CL96 PaTu 8988t C84(0.45)  LDD1370  [5]
 LDCM0492  CL97 PaTu 8988t C84(0.47)  LDD1371  [5]
 LDCM0493  CL98 PaTu 8988t C84(0.52)  LDD1372  [5]
 LDCM0494  CL99 PaTu 8988t C84(0.57)  LDD1373  [5]
 LDCM0495  E2913 HEK-293T C289(1.16)  LDD1698  [10]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C221(1.62)  LDD1702  [11]
 LDCM0468  Fragment33 HCT 116 C84(1.25)  LDD0785  [5]
 LDCM0427  Fragment51 HEK-293T C289(0.91)  LDD1631  [10]
 LDCM0022  KB02 769-P C221(2.19)  LDD2246  [12]
 LDCM0023  KB03 MDA-MB-231 C221(2.94)  LDD1701  [11]
 LDCM0024  KB05 HMCB C221(1.05)  LDD3312  [12]
 LDCM0021  THZ1 HCT 116 C84(1.15)  LDD2173  [5]

References

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Mass spectrometry data entry: PXD028270
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
9 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
12 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840