Details of the Target

General Information of Target

Target ID LDTP18515
Target Name Protein FAM135A (FAM135A)
Gene Name FAM135A
Gene ID 57579
Synonyms
KIAA1411; Protein FAM135A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
Download
Sequence
MEPLAPMRLYTLSKRHFVLVFVVFFICFGLTIFVGIRGPKVIQTSAANFSLNNSKKLKPI
QILSNPLSTYNQQLWLTCVVELDQSKETSIKTSFPMTVKVDGVAQDGTTMYIHNKVHNRT
RTLTCAGKCAEIIVAHLGYLNYTQYTVIVGFEHLKLPIKGMNFTWKTYNPAFSRLEIWFR
FFFVVLTFIVTCLFAHSLRKFSMRDWGIEQKWMSVLLPLLLLYNDPFFPLSFLVNSWLPG
MLDDLFQSMFLCALLLFWLCVYHGIRVQGERKCLTFYLPKFFIVGLLWLASVTLGIWQTV
NELHDPMYQYRVDTGNFQGMKVFFMVVAAVYILYLLFLIVRACSELRHMPYVDLRLKFLT
ALTFVVLVISIAILYLRFGAQVLQDNFVAELSTHYQNSAEFLSFYGLLNFYLYTLAFVYS
PSKNALYESQLKDNPAFSMLNDSDDDVIYGSDYEEMPLQNGQAIRAKYKEESDSD
Target Bioclass
Other
Family
FAM135 family
Uniprot ID
Q9P2D6
Ensemble ID
ENST00000361499.7
HGNC ID
HGNC:21084

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA SNV: p.K706N; p.I890V; p.Q1449L .
CAL148 SNV: p.S889G .
COLO320 SNV: p.L1360R DBIA    Probe Info 
CORL23 SNV: p.S1406C .
EFO21 SNV: p.E3K .
FADU SNV: p.R1341M .
HCT116 Deletion: p.N999IfsTer5
SNV: p.R1160Ter		 DBIA    Probe Info 
HLF SNV: p.S202A .
HS936T SNV: p.V1428A .
HT115 SNV: p.D401Y .
LS180 SNV: p.F696S DBIA    Probe Info 
MEWO SNV: p.S845F .
MFE319 Deletion: p.G1278EfsTer22 .
NUGC3 Insertion: p.N999KfsTer2 .
OAW42 SNV: p.V859I .
PATU8988T SNV: p.S221P .
SW1271 SNV: p.F89I .
SW756 SNV: p.S1169C .
WM793 SNV: p.P41A .
YSCCC SNV: p.E1286Q .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C938(0.80); C948(0.80)  LDD0533  [1]
IPM
 Probe Info  		N.A.  LDD2156  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C948(0.81); C938(0.81)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C948(0.96); C353(0.87); C938(1.04)  LDD0813  [1]
 LDCM0216  AC100 HCT 116 C938(0.80); C948(0.80)  LDD0533  [1]
 LDCM0217  AC101 HCT 116 C938(0.93); C948(0.93)  LDD0534  [1]
 LDCM0218  AC102 HCT 116 C938(0.90); C948(0.90)  LDD0535  [1]
 LDCM0219  AC103 HCT 116 C938(1.23); C948(1.23)  LDD0536  [1]
 LDCM0220  AC104 HCT 116 C938(1.14); C948(1.14)  LDD0537  [1]
 LDCM0221  AC105 HCT 116 C938(1.02); C948(1.02)  LDD0538  [1]
 LDCM0222  AC106 HCT 116 C938(1.42); C948(1.42)  LDD0539  [1]
 LDCM0223  AC107 HCT 116 C938(1.01); C948(1.01)  LDD0540  [1]
 LDCM0224  AC108 HCT 116 C938(0.92); C948(0.92)  LDD0541  [1]
 LDCM0225  AC109 HCT 116 C938(1.22); C948(1.22)  LDD0542  [1]
 LDCM0226  AC11 HEK-293T C948(1.01); C353(0.97); C938(0.98)  LDD0824  [1]
 LDCM0227  AC110 HCT 116 C938(1.13); C948(1.13)  LDD0544  [1]
 LDCM0228  AC111 HCT 116 C938(1.30); C948(1.30)  LDD0545  [1]
 LDCM0229  AC112 HCT 116 C938(1.50); C948(1.50)  LDD0546  [1]
 LDCM0230  AC113 HCT 116 C938(0.84); C948(0.84)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C938(0.77); C948(0.77)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C938(0.76); C948(0.76)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C938(1.15); C948(1.15)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C938(0.69); C948(0.69)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C938(0.62); C948(0.62)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C938(0.71); C948(0.71)  LDD0553  [1]
 LDCM0237  AC12 HEK-293T C948(0.99); C353(0.96); C938(1.01)  LDD0835  [1]
 LDCM0238  AC120 HCT 116 C938(1.12); C948(1.12)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C938(0.79); C948(0.79)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C938(0.79); C948(0.79)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C938(0.77); C948(0.77)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C938(0.67); C948(0.67)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C938(0.78); C948(0.78)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C938(0.86); C948(0.86)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C938(0.55); C948(0.55)  LDD0562  [1]
 LDCM0246  AC128 HEK-293T C948(1.26); C1391(1.19); C938(1.26)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C948(1.26); C1391(0.94); C938(1.26)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C948(1.46); C1391(1.23); C938(1.46)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C948(1.49); C1391(1.83); C938(1.49)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C948(1.39); C1391(1.06); C938(1.39)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C948(1.46); C1391(1.18); C938(1.46)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C948(1.52); C1391(1.33); C938(1.52)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C948(1.37); C1391(1.45); C938(1.37)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C948(0.77); C1391(1.09); C938(0.77)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C948(1.44); C1391(1.20); C938(1.44)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C948(1.63); C1391(1.27); C938(1.63)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C948(1.37); C1391(1.33); C938(1.37)  LDD0856  [1]
 LDCM0259  AC14 HEK-293T C948(1.38); C353(0.98); C938(1.25)  LDD0857  [1]
 LDCM0260  AC140 HEK-293T C948(1.24); C1391(1.06); C938(1.24)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C948(1.28); C1391(1.31); C938(1.28)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C948(1.57); C1391(0.98); C938(1.57)  LDD0860  [1]
 LDCM0263  AC143 HCT 116 C938(0.97); C948(0.97)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C938(0.81); C948(0.81)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C938(0.91); C948(0.91)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C938(0.80); C948(0.80)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C938(1.41); C948(1.41)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C938(1.66); C948(1.66)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C938(1.29); C948(1.29)  LDD0586  [1]
 LDCM0270  AC15 HEK-293T C948(1.28); C353(1.00); C938(1.26)  LDD0868  [1]
 LDCM0271  AC150 HCT 116 C938(0.97); C948(0.97)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C938(0.79); C948(0.79)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C938(1.60); C948(1.60)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C938(1.65); C948(1.65)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C938(0.98); C948(0.98)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C938(0.97); C948(0.97)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C938(0.78); C948(0.78)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C938(1.04); C948(1.04)  LDD2161  [1]
 LDCM0276  AC17 HEK-293T C938(1.51)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C938(1.25)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C938(1.13)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C948(1.08); C938(1.08)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C938(1.86)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C938(1.04)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C938(1.30)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C938(1.89)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C938(1.13)  LDD0882  [1]
 LDCM0285  AC25 HEK-293T C948(0.62); C938(0.62)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C948(0.61); C938(0.61)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C948(0.59); C938(0.59)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C948(0.49); C938(0.49)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C948(0.62); C938(0.62)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C948(0.97); C938(0.97)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C948(0.61); C938(0.61)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C948(0.59); C938(0.59)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C948(0.53); C938(0.53)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C948(0.68); C938(0.68)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C948(0.63); C938(0.63)  LDD0893  [1]
 LDCM0296  AC35 HCT 116 C938(1.08); C948(1.08)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C938(0.99); C948(0.99)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C938(0.96); C948(0.96)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C938(1.08); C948(1.08)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C938(1.01); C948(1.01)  LDD0617  [1]
 LDCM0301  AC4 HEK-293T C948(0.83); C938(0.83)  LDD0899  [1]
 LDCM0302  AC40 HCT 116 C938(0.99); C948(0.99)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C938(1.00); C948(1.00)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C938(1.24); C948(1.24)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C938(1.66); C948(1.66)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C938(1.33); C948(1.33)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C938(2.28); C948(2.28)  LDD0624  [1]
 LDCM0308  AC46 HEK-293T C948(0.96); C938(0.91)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C948(1.10); C938(0.99)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C948(0.89); C938(0.98)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C948(0.79); C938(0.86)  LDD0909  [1]
 LDCM0312  AC5 HEK-293T C948(1.05); C938(1.05)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C948(1.18); C938(1.02)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C948(1.22); C938(0.93)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C948(1.19); C938(1.29)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C948(1.81); C938(1.98)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C948(1.06); C938(1.19)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C948(0.95); C938(1.19)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C948(1.23); C938(0.85)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C948(1.19); C1391(1.00); C938(1.19)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C948(1.36); C1391(0.99); C938(1.36)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C948(1.03); C1391(0.85); C938(1.03)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C948(1.16); C353(0.89); C938(1.06)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C948(0.93); C1391(0.91); C938(0.93)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C948(1.53); C1391(0.99); C938(1.53)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C948(1.32); C1391(0.97); C938(1.32)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C948(1.36); C1391(0.92); C938(1.36)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C948(1.33); C1391(0.99); C938(1.33)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C948(1.38); C1391(1.07); C938(1.38)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C948(1.25); C1391(1.12); C938(1.25)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C948(1.34); C1391(1.11); C938(1.34)  LDD0929  [1]
 LDCM0332  AC68 HCT 116 C938(1.13); C948(1.13)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C938(1.02); C948(1.02)  LDD0650  [1]
 LDCM0334  AC7 HEK-293T C948(0.95); C353(1.02); C938(1.02)  LDD0932  [1]
 LDCM0335  AC70 HCT 116 C938(0.66); C948(0.66)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C938(1.00); C948(1.00)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C938(0.68); C948(0.68)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C938(0.92); C948(0.92)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C938(1.06); C948(1.06)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C938(0.73); C948(0.73)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C938(0.83); C948(0.83)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C938(1.49); C948(1.49)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C938(1.20); C948(1.20)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C938(0.82); C948(0.82)  LDD0661  [1]
 LDCM0345  AC8 HEK-293T C948(0.90); C353(1.03); C938(1.07)  LDD0943  [1]
 LDCM0346  AC80 HCT 116 C938(0.93); C948(0.93)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C938(0.98); C948(0.98)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C938(0.75); C948(0.75)  LDD0665  [1]
 LDCM0349  AC83 HEK-293T C948(0.77); C1391(0.88); C938(0.90)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C948(0.91); C1391(1.03); C938(1.11)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C948(0.88); C1391(1.20); C938(1.02)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C948(0.92); C1391(0.96); C938(1.00)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C948(0.89); C1391(0.79); C938(0.98)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C948(0.94); C1391(0.69); C938(1.10)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C948(0.81); C1391(0.93); C938(0.99)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C948(0.90); C1391(0.88); C938(1.08)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C948(0.83); C1391(1.08); C938(1.06)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C948(0.83); C1391(0.86); C938(0.99)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C948(0.64); C1391(0.90); C938(0.87)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C948(0.71); C1391(0.55); C938(0.98)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C948(0.61); C1391(0.88); C938(0.91)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C948(0.77); C1391(0.65); C938(0.94)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C948(0.75); C1391(0.93); C938(1.10)  LDD0962  [1]
 LDCM0365  AC98 HCT 116 C938(0.97); C948(0.97)  LDD0682  [1]
 LDCM0366  AC99 HCT 116 C938(0.95); C948(0.95)  LDD0683  [1]
 LDCM0248  AKOS034007472 HEK-293T C948(1.27); C353(1.02); C938(1.12)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C948(0.96); C353(1.07); C938(1.11)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C948(1.40); C353(1.04); C938(1.27)  LDD0873  [1]
 LDCM0020  ARS-1620 HCC44 C938(1.13); C948(1.13)  LDD2171  [1]
 LDCM0367  CL1 HEK-293T C353(1.09)  LDD0965  [1]
 LDCM0368  CL10 HEK-293T C353(2.76)  LDD0966  [1]
 LDCM0369  CL100 HEK-293T C948(0.93); C938(0.93)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C948(1.25); C353(1.18); C938(1.21)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C948(1.91); C353(1.00); C938(1.51)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C948(0.79); C353(0.97); C938(0.99)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C948(0.93); C353(0.98); C938(1.07)  LDD0971  [1]
 LDCM0374  CL105 HEK-293T C938(1.02)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C938(1.00)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C938(1.06)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C938(1.00)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C938(0.91)  LDD0976  [1]
 LDCM0379  CL11 HEK-293T C353(2.01)  LDD0977  [1]
 LDCM0380  CL110 HEK-293T C938(1.25)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C938(1.02)  LDD0979  [1]
 LDCM0382  CL112 HEK-293T C948(0.94); C938(0.94)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C948(0.65); C938(0.65)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C948(0.62); C938(0.62)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C948(0.60); C938(0.60)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C948(0.54); C938(0.54)  LDD0984  [1]
 LDCM0387  CL117 HCT 116 C938(0.86); C948(0.86)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C938(1.24); C948(1.24)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C938(1.30); C948(1.30)  LDD0706  [1]
 LDCM0390  CL12 HEK-293T C353(1.66)  LDD0988  [1]
 LDCM0391  CL120 HCT 116 C938(0.77); C948(0.77)  LDD0708  [1]
 LDCM0392  CL121 HEK-293T C948(1.40); C938(1.07)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C948(0.81); C938(0.89)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C948(1.94); C938(1.96)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C948(1.45); C938(1.10)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C948(1.21); C1391(0.93); C938(1.21)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C948(1.23); C1391(0.70); C938(1.23)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C948(1.49); C1391(1.11); C938(1.49)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C948(1.01); C1391(0.84); C938(1.01)  LDD0997  [1]
 LDCM0400  CL13 HEK-293T C353(1.36)  LDD0998  [1]
 LDCM0401  CL14 HEK-293T C353(1.78)  LDD0999  [1]
 LDCM0402  CL15 HEK-293T C353(2.13)  LDD1000  [1]
 LDCM0403  CL16 HCT 116 C938(0.77); C948(0.77)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C938(0.78); C948(0.78)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C938(0.85); C948(0.85)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C938(0.86); C948(0.86)  LDD0723  [1]
 LDCM0407  CL2 HEK-293T C353(1.79)  LDD1005  [1]
 LDCM0408  CL20 HCT 116 C938(1.00); C948(1.00)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C938(1.00); C948(1.00)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C938(1.16); C948(1.16)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C938(1.48); C948(1.48)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C938(0.93); C948(0.93)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C938(0.94); C948(0.94)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C938(0.91); C948(0.91)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C938(0.91); C948(0.91)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C938(0.82); C948(0.82)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C938(1.06); C948(1.06)  LDD0734  [1]
 LDCM0418  CL3 HEK-293T C353(1.12)  LDD1016  [1]
 LDCM0419  CL30 HCT 116 C938(0.73); C948(0.73)  LDD0736  [1]
 LDCM0420  CL31 HCT 116 C938(1.01); C948(1.01)  LDD0737  [1]
 LDCM0421  CL32 HEK-293T C948(1.06); C353(1.67); C938(1.02)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C948(1.49); C353(0.98); C938(1.19)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C948(0.84); C353(1.10); C938(0.98)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C948(1.02); C353(1.47); C938(1.08)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C948(0.93); C353(1.21); C938(0.98)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C948(1.16); C353(1.30); C938(1.13)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C948(1.10); C353(2.07); C938(1.21)  LDD1026  [1]
 LDCM0429  CL4 HEK-293T C353(1.17)  LDD1027  [1]
 LDCM0430  CL40 HEK-293T C948(1.02); C353(1.46); C938(1.02)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C948(1.51); C353(2.35); C938(1.35)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C948(1.13); C353(2.06); C938(1.36)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C948(1.14); C353(2.01); C938(1.30)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C948(1.09); C353(1.27); C938(1.13)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C948(0.93); C353(1.92); C938(1.13)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C353(1.20); C938(1.14)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C353(1.11); C938(1.07)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C353(1.24); C938(1.01)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C353(1.51); C938(1.13)  LDD1037  [1]
 LDCM0440  CL5 HEK-293T C353(1.74)  LDD1038  [1]
 LDCM0441  CL50 HEK-293T C353(1.61); C938(1.41)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C353(1.25); C938(1.13)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C353(0.83); C938(0.93)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C353(0.94); C938(0.96)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C353(1.09); C938(1.17)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C353(1.06); C938(1.19)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C353(1.21); C938(1.01)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C353(0.82); C938(1.13)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C353(0.93); C938(1.12)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C353(1.20); C938(1.31)  LDD1048  [1]
 LDCM0451  CL6 HEK-293T C353(1.20)  LDD1049  [1]
 LDCM0452  CL60 HEK-293T C353(1.58); C938(1.21)  LDD1050  [1]
 LDCM0453  CL61 HCT 116 C938(0.91); C948(0.91)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C938(0.85); C948(0.85)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C938(1.42); C948(1.42)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C938(1.31); C948(1.31)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C938(1.01); C948(1.01)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C938(1.25); C948(1.25)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C938(1.46); C948(1.46)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C938(0.96); C948(0.96)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C938(0.92); C948(0.92)  LDD0778  [1]
 LDCM0462  CL7 HEK-293T C353(2.11)  LDD1060  [1]
 LDCM0463  CL70 HCT 116 C938(1.17); C948(1.17)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C938(1.50); C948(1.50)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C938(1.07); C948(1.07)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C938(1.35); C948(1.35)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C938(1.10); C948(1.10)  LDD0784  [1]
 LDCM0469  CL76 HCT 116 C938(1.72); C948(1.72)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C938(1.38); C948(1.38)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C938(1.07); C948(1.07)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C938(0.98); C948(0.98)  LDD0789  [1]
 LDCM0473  CL8 HEK-293T C287(1.06)  LDD1676  [3]
 LDCM0474  CL80 HCT 116 C938(1.63); C948(1.63)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C938(0.88); C948(0.88)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C938(0.67); C948(0.67)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C938(1.39); C948(1.39)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C938(1.30); C948(1.30)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C938(1.79); C948(1.79)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C938(1.03); C948(1.03)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C938(0.77); C948(0.77)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C938(0.78); C948(0.78)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C938(1.30); C948(1.30)  LDD0800  [1]
 LDCM0484  CL9 HEK-293T C287(1.03)  LDD1687  [3]
 LDCM0485  CL90 HCT 116 C938(1.11); C948(1.11)  LDD0802  [1]
 LDCM0486  CL91 HEK-293T C948(1.03); C938(1.03)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C948(1.03); C938(1.03)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C948(0.96); C938(0.96)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C948(1.19); C938(1.19)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C948(1.45); C938(1.45)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C948(1.21); C938(1.21)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C948(1.49); C938(1.49)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C948(1.06); C938(1.06)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C948(1.01); C938(1.01)  LDD1092  [1]
 LDCM0495  E2913 HEK-293T C287(0.90)  LDD1698  [3]
 LDCM0468  Fragment33 HCT 116 C938(1.29); C948(1.29)  LDD0785  [1]
 LDCM0427  Fragment51 HEK-293T C948(0.80); C353(1.56); C938(0.93)  LDD1025  [1]
 LDCM0022  KB02 HEK-293T C287(0.98); C385(1.03)  LDD1492  [3]
 LDCM0023  KB03 HEK-293T C287(1.01); C385(0.90)  LDD1497  [3]
 LDCM0024  KB05 PaTu 8988t C287(2.31)  LDD3393  [4]
 LDCM0021  THZ1 HCT 116 C938(1.13); C948(1.13)  LDD2173  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840