Details of the Target

General Information of Target

Target ID LDTP17593
Target Name Intraflagellar transport protein 70A (IFT70A)
Gene Name IFT70A
Gene ID 92104
Synonyms
TTC30A; Intraflagellar transport protein 70A; Tetratricopeptide repeat protein 30A; TPR repeat protein 30A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNWVGGSRSRVLIKQERRKQKEYFEKHRLKSKMKSLGVLSPVKNSAVSLDILNLYMVNQI
SCKKKIPETVRKPTHVNMNRDIKMPLRKHNLELTMSPHCVPSKLCLDDTETNVNCQRLSS
KEDLGPVQSQGMDSYSMLHPQFSKIENCSFTPSSFSVELPSNRHISKLNFTSGIAPTPQK
LAYEKKQNDQRSTVNCSDSLLSKLNKSQDVFSPSHKTTRFGTLFERLNSLGNRNLLTKSP
AVIMDEDCRSTDEIRQSDYITEKHSIQHIWGKNGKEVSNFLEDVNQSTPNLLSENCDSFV
SQNMINVLNIDEQRIKKTFNKCDYDSMGDTCVVTSSDKNHVTDRCIRNIFTVPELTFSNS
TLNKTSYPEKCQPNKKYQREYNKNERNDLSTSFENDYYPSSSERKEKFENDYQEKTPQKS
IQKYPANSMGNIPSEELHSKQSWDFGLDEILMEEGGIYSLKSKRISTKKISLDSAQSSRS
TSYSPRPTDSCFSSSSDLPSEDEDQISQQIEDSNRMTIKTKEKMNNFYVERMAKLSGDRI
VKNDDKIHKQNENFYQFSVKNNTDQFPQLQCNSAHILQNKTNDNCVLQAARCDAGIQTES
ESVMEEKLDVAIQCDLISKCTCRSDVSLCNLERCSGNIKADTTGGQEIHKNN
Target Bioclass
Other
Family
TTC30/dfy-1/fleer family
Subcellular location
Cell projection, cilium
Function
Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
Uniprot ID
Q86WT1
Ensemble ID
ENST00000355689.6
HGNC ID
HGNC:25853

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C454(10.10)  LDD0371  [1]
DBIA
 Probe Info  		C93(1.03)  LDD0531  [2]
AOyne
 Probe Info  		13.10  LDD0443  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C454(10.10)  LDD0371  [1]
 LDCM0214  AC1 HCT 116 C93(1.03)  LDD0531  [2]
 LDCM0215  AC10 HEK-293T C174(1.17); C589(0.98); C93(1.30)  LDD0813  [2]
 LDCM0216  AC100 HCT 116 C93(0.43)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C93(0.45)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C93(0.55)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C93(0.47)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C93(0.41)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C93(0.48)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C93(0.45)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C93(0.49)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C93(0.38)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C93(0.49)  LDD0542  [2]
 LDCM0226  AC11 HEK-293T C174(1.05); C589(0.95); C93(1.54)  LDD0824  [2]
 LDCM0227  AC110 HCT 116 C93(0.43)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C93(0.50)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C93(0.61)  LDD0546  [2]
 LDCM0230  AC113 HEK-293T C174(0.86)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C174(1.15)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C174(1.04)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C174(0.85)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C174(0.92)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C174(0.89)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C174(0.91)  LDD0834  [2]
 LDCM0237  AC12 HEK-293T C174(1.14); C589(1.18); C93(1.32)  LDD0835  [2]
 LDCM0238  AC120 HEK-293T C174(0.81)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C174(0.91)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C174(1.10)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C174(0.92)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C174(0.87)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C174(0.93)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C174(1.03)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C174(1.27)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C174(1.22); C93(1.28)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C174(1.24); C93(0.78)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C174(1.37); C93(0.84)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C174(1.24); C93(1.48)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C174(1.81); C93(0.98)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C174(1.23); C93(0.99)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C174(1.38); C93(1.18)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C174(1.43); C93(1.19)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C174(1.64); C93(1.01)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C174(1.46); C93(1.01)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C174(1.28); C93(0.96)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C174(1.13); C93(1.07)  LDD0856  [2]
 LDCM0259  AC14 HEK-293T C174(1.02); C589(0.96); C93(1.30)  LDD0857  [2]
 LDCM0260  AC140 HEK-293T C174(1.57); C93(1.11)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C174(1.58); C93(0.93)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C174(1.27); C93(1.06)  LDD0860  [2]
 LDCM0263  AC143 PaTu 8988t C589(0.90)  LDD1142  [2]
 LDCM0264  AC144 PaTu 8988t C589(0.77)  LDD1143  [2]
 LDCM0265  AC145 PaTu 8988t C589(0.79)  LDD1144  [2]
 LDCM0266  AC146 PaTu 8988t C589(0.92)  LDD1145  [2]
 LDCM0267  AC147 PaTu 8988t C589(0.85)  LDD1146  [2]
 LDCM0268  AC148 PaTu 8988t C589(0.81)  LDD1147  [2]
 LDCM0269  AC149 PaTu 8988t C589(0.86)  LDD1148  [2]
 LDCM0270  AC15 HEK-293T C174(1.16); C589(0.78); C93(1.06)  LDD0868  [2]
 LDCM0271  AC150 PaTu 8988t C589(0.84)  LDD1150  [2]
 LDCM0272  AC151 PaTu 8988t C589(0.91)  LDD1151  [2]
 LDCM0273  AC152 PaTu 8988t C589(0.79)  LDD1152  [2]
 LDCM0274  AC153 PaTu 8988t C589(0.77)  LDD1153  [2]
 LDCM0621  AC154 PaTu 8988t C589(0.87)  LDD2166  [2]
 LDCM0622  AC155 PaTu 8988t C589(0.87)  LDD2167  [2]
 LDCM0623  AC156 PaTu 8988t C589(0.80)  LDD2168  [2]
 LDCM0624  AC157 PaTu 8988t C589(0.80)  LDD2169  [2]
 LDCM0276  AC17 HEK-293T C174(1.02); C589(0.68)  LDD0874  [2]
 LDCM0277  AC18 HEK-293T C174(1.06); C589(0.76)  LDD0875  [2]
 LDCM0278  AC19 HEK-293T C174(1.08); C589(0.77)  LDD0876  [2]
 LDCM0279  AC2 HCT 116 C93(0.90)  LDD0596  [2]
 LDCM0280  AC20 HEK-293T C174(1.11); C589(0.73)  LDD0878  [2]
 LDCM0281  AC21 HEK-293T C174(1.05); C589(0.86)  LDD0879  [2]
 LDCM0282  AC22 HEK-293T C174(1.20); C589(0.72)  LDD0880  [2]
 LDCM0283  AC23 HEK-293T C174(1.05); C589(1.50)  LDD0881  [2]
 LDCM0284  AC24 HEK-293T C174(1.12); C589(0.67)  LDD0882  [2]
 LDCM0285  AC25 HEK-293T C174(1.09)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C174(0.67)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C174(0.86)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C174(0.87)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C174(0.82)  LDD0887  [2]
 LDCM0290  AC3 HCT 116 C93(1.06)  LDD0607  [2]
 LDCM0291  AC30 HEK-293T C174(0.97)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C174(0.75)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C174(0.77)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C174(0.74)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C174(0.86)  LDD0893  [2]
 LDCM0296  AC35 HCT 116 C93(1.16)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C93(1.25)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C93(0.96)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C93(1.21)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C93(1.16)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C93(1.06)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C93(1.28)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C93(1.06)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C93(1.10)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C93(1.09)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C93(1.19)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C93(1.05)  LDD0624  [2]
 LDCM0308  AC46 HEK-293T C174(0.97); C589(1.34)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C174(0.83); C589(1.15)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C174(0.98); C589(1.44)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C174(1.08); C589(1.11)  LDD0909  [2]
 LDCM0312  AC5 HCT 116 C93(0.93)  LDD0629  [2]
 LDCM0313  AC50 HEK-293T C174(0.95); C589(1.42)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C174(1.00); C589(1.78)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C174(1.09); C589(1.54)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C174(0.96); C589(1.37)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C174(0.97); C589(1.39)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C174(1.09); C589(1.43)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C174(1.31); C589(1.50)  LDD0917  [2]
 LDCM0320  AC57 HEK-293T C174(1.17); C93(1.06)  LDD0918  [2]
 LDCM0321  AC58 HEK-293T C174(1.13); C93(0.89)  LDD0919  [2]
 LDCM0322  AC59 HEK-293T C174(1.01); C93(1.07)  LDD0920  [2]
 LDCM0323  AC6 HEK-293T C174(1.15); C589(0.74); C93(1.37)  LDD0921  [2]
 LDCM0324  AC60 HEK-293T C174(0.93); C93(0.73)  LDD0922  [2]
 LDCM0325  AC61 HEK-293T C174(0.87); C93(0.88)  LDD0923  [2]
 LDCM0326  AC62 HEK-293T C174(0.95); C93(1.07)  LDD0924  [2]
 LDCM0327  AC63 HEK-293T C174(1.04); C93(0.83)  LDD0925  [2]
 LDCM0328  AC64 HEK-293T C174(1.16); C93(0.76)  LDD0926  [2]
 LDCM0329  AC65 HEK-293T C174(1.04); C93(0.95)  LDD0927  [2]
 LDCM0330  AC66 HEK-293T C174(0.82); C93(0.91)  LDD0928  [2]
 LDCM0331  AC67 HEK-293T C174(1.02); C93(1.01)  LDD0929  [2]
 LDCM0332  AC68 HEK-293T C174(0.90); C589(0.87); C93(1.06)  LDD0930  [2]
 LDCM0333  AC69 HEK-293T C174(1.15); C589(0.72); C93(0.92)  LDD0931  [2]
 LDCM0334  AC7 HEK-293T C174(1.56); C589(1.15); C93(1.40)  LDD0932  [2]
 LDCM0335  AC70 HEK-293T C174(0.87); C589(0.77); C93(0.84)  LDD0933  [2]
 LDCM0336  AC71 HEK-293T C174(1.15); C589(0.74); C93(1.01)  LDD0934  [2]
 LDCM0337  AC72 HEK-293T C174(0.97); C589(0.64); C93(0.80)  LDD0935  [2]
 LDCM0338  AC73 HEK-293T C174(0.94); C589(0.82); C93(0.75)  LDD0936  [2]
 LDCM0339  AC74 HEK-293T C174(0.94); C589(0.69); C93(0.72)  LDD0937  [2]
 LDCM0340  AC75 HEK-293T C174(0.92); C589(0.72); C93(1.01)  LDD0938  [2]
 LDCM0341  AC76 HEK-293T C174(0.82); C589(0.71); C93(1.01)  LDD0939  [2]
 LDCM0342  AC77 HEK-293T C174(1.14); C589(0.89); C93(0.96)  LDD0940  [2]
 LDCM0343  AC78 HEK-293T C174(1.18); C589(0.80); C93(1.09)  LDD0941  [2]
 LDCM0344  AC79 HEK-293T C174(1.03); C589(0.98); C93(1.09)  LDD0942  [2]
 LDCM0345  AC8 HEK-293T C174(1.21); C589(0.80); C93(1.28)  LDD0943  [2]
 LDCM0346  AC80 HEK-293T C174(1.08); C589(0.82); C93(0.78)  LDD0944  [2]
 LDCM0347  AC81 HEK-293T C174(1.00); C589(0.66); C93(1.09)  LDD0945  [2]
 LDCM0348  AC82 HEK-293T C174(1.08); C589(0.64); C93(1.04)  LDD0946  [2]
 LDCM0349  AC83 HEK-293T C174(1.02); C93(1.34)  LDD0947  [2]
 LDCM0350  AC84 HEK-293T C174(0.89); C93(1.02)  LDD0948  [2]
 LDCM0351  AC85 HEK-293T C174(1.07); C93(1.27)  LDD0949  [2]
 LDCM0352  AC86 HEK-293T C174(1.01); C93(1.07)  LDD0950  [2]
 LDCM0353  AC87 HEK-293T C174(0.93); C93(1.24)  LDD0951  [2]
 LDCM0354  AC88 HEK-293T C174(0.98); C93(1.18)  LDD0952  [2]
 LDCM0355  AC89 HEK-293T C174(0.99); C93(1.12)  LDD0953  [2]
 LDCM0357  AC90 HEK-293T C174(0.92); C93(1.19)  LDD0955  [2]
 LDCM0358  AC91 HEK-293T C174(0.97); C93(1.37)  LDD0956  [2]
 LDCM0359  AC92 HEK-293T C174(0.92); C93(1.08)  LDD0957  [2]
 LDCM0360  AC93 HEK-293T C174(0.87); C93(0.92)  LDD0958  [2]
 LDCM0361  AC94 HEK-293T C174(0.98); C93(1.20)  LDD0959  [2]
 LDCM0362  AC95 HEK-293T C174(1.01); C93(1.20)  LDD0960  [2]
 LDCM0363  AC96 HEK-293T C174(1.03); C93(0.97)  LDD0961  [2]
 LDCM0364  AC97 HEK-293T C174(1.25); C93(1.05)  LDD0962  [2]
 LDCM0365  AC98 HCT 116 C93(0.54)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C93(0.61)  LDD0683  [2]
 LDCM0248  AKOS034007472 HEK-293T C174(0.99); C589(2.10); C93(1.56)  LDD0846  [2]
 LDCM0356  AKOS034007680 HEK-293T C174(1.07); C589(1.10); C93(1.29)  LDD0954  [2]
 LDCM0275  AKOS034007705 HEK-293T C174(0.99); C589(1.19); C93(1.17)  LDD0873  [2]
 LDCM0367  CL1 HEK-293T C174(2.16); C93(1.12)  LDD0965  [2]
 LDCM0368  CL10 HEK-293T C174(1.96); C93(0.89)  LDD0966  [2]
 LDCM0369  CL100 HCT 116 C93(1.09)  LDD0686  [2]
 LDCM0370  CL101 HEK-293T C174(1.06); C589(0.89); C93(1.15)  LDD0968  [2]
 LDCM0371  CL102 HEK-293T C174(1.00); C589(1.21); C93(1.05)  LDD0969  [2]
 LDCM0372  CL103 HEK-293T C174(1.11); C589(1.02); C93(1.11)  LDD0970  [2]
 LDCM0373  CL104 HEK-293T C174(0.98); C589(0.90); C93(1.23)  LDD0971  [2]
 LDCM0374  CL105 HEK-293T C174(1.22); C589(0.80)  LDD0972  [2]
 LDCM0375  CL106 HEK-293T C174(0.96); C589(0.76)  LDD0973  [2]
 LDCM0376  CL107 HEK-293T C174(1.16); C589(0.74)  LDD0974  [2]
 LDCM0377  CL108 HEK-293T C174(0.97); C589(0.50)  LDD0975  [2]
 LDCM0378  CL109 HEK-293T C174(1.02); C589(1.05)  LDD0976  [2]
 LDCM0379  CL11 HEK-293T C174(1.55); C93(1.32)  LDD0977  [2]
 LDCM0380  CL110 HEK-293T C174(1.09); C589(0.94)  LDD0978  [2]
 LDCM0381  CL111 HEK-293T C174(1.19); C589(0.93)  LDD0979  [2]
 LDCM0382  CL112 HEK-293T C174(0.95)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C174(0.63)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C174(0.99)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C174(0.92)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C174(0.83)  LDD0984  [2]
 LDCM0387  CL117 HCT 116 C93(1.45)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C93(1.13)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C93(1.10)  LDD0706  [2]
 LDCM0390  CL12 HEK-293T C174(1.52); C93(1.38)  LDD0988  [2]
 LDCM0391  CL120 HCT 116 C93(1.21)  LDD0708  [2]
 LDCM0392  CL121 HEK-293T C174(0.96); C589(1.27)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C174(0.90); C589(1.16)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C174(0.78); C589(1.37)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C174(0.90); C589(1.21)  LDD0993  [2]
 LDCM0396  CL125 HEK-293T C174(0.97); C93(1.02)  LDD0994  [2]
 LDCM0397  CL126 HEK-293T C174(0.99); C93(0.78)  LDD0995  [2]
 LDCM0398  CL127 HEK-293T C174(0.92); C93(1.01)  LDD0996  [2]
 LDCM0399  CL128 HEK-293T C174(1.09); C93(1.04)  LDD0997  [2]
 LDCM0400  CL13 HEK-293T C174(1.61); C93(1.33)  LDD0998  [2]
 LDCM0401  CL14 HEK-293T C174(1.55); C93(1.06)  LDD0999  [2]
 LDCM0402  CL15 HEK-293T C174(1.43); C93(1.27)  LDD1000  [2]
 LDCM0403  CL16 HCT 116 C93(1.02)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C93(1.31)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C93(0.95)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C93(1.00)  LDD0723  [2]
 LDCM0407  CL2 HEK-293T C174(1.36); C93(0.93)  LDD1005  [2]
 LDCM0408  CL20 HCT 116 C93(0.69)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C93(1.00)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C93(1.24)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C93(0.90)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C93(0.78)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C93(0.94)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C93(0.85)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C93(1.00)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C93(0.86)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C93(0.95)  LDD0734  [2]
 LDCM0418  CL3 HEK-293T C174(1.70); C93(1.05)  LDD1016  [2]
 LDCM0419  CL30 HCT 116 C93(0.76)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C93(0.48)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C93(0.43)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C93(0.38)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C93(0.58)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C93(0.37)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C93(0.44)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C93(0.53)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C93(0.53)  LDD0745  [2]
 LDCM0429  CL4 HEK-293T C174(1.41); C93(1.04)  LDD1027  [2]
 LDCM0430  CL40 HCT 116 C93(0.46)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C93(0.52)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C93(0.44)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C93(0.71)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C93(0.31)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C93(0.88)  LDD0752  [2]
 LDCM0436  CL46 PaTu 8988t C174(0.92); C54(0.75)  LDD1315  [2]
 LDCM0437  CL47 PaTu 8988t C174(0.96); C54(0.59)  LDD1316  [2]
 LDCM0438  CL48 PaTu 8988t C174(0.80); C54(0.70)  LDD1317  [2]
 LDCM0439  CL49 PaTu 8988t C174(0.94); C54(0.70)  LDD1318  [2]
 LDCM0440  CL5 HEK-293T C174(1.45); C93(0.96)  LDD1038  [2]
 LDCM0441  CL50 PaTu 8988t C174(0.80); C54(0.78)  LDD1320  [2]
 LDCM0442  CL51 PaTu 8988t C174(1.08); C54(0.61)  LDD1321  [2]
 LDCM0443  CL52 PaTu 8988t C174(0.97); C54(0.66)  LDD1322  [2]
 LDCM0444  CL53 PaTu 8988t C174(0.87); C54(0.40)  LDD1323  [2]
 LDCM0445  CL54 PaTu 8988t C174(0.95); C54(0.65)  LDD1324  [2]
 LDCM0446  CL55 PaTu 8988t C174(0.75); C54(0.87)  LDD1325  [2]
 LDCM0447  CL56 PaTu 8988t C174(0.79); C54(0.58)  LDD1326  [2]
 LDCM0448  CL57 PaTu 8988t C174(0.93); C54(0.72)  LDD1327  [2]
 LDCM0449  CL58 PaTu 8988t C174(0.89); C54(0.77)  LDD1328  [2]
 LDCM0450  CL59 PaTu 8988t C174(0.87); C54(1.02)  LDD1329  [2]
 LDCM0451  CL6 HEK-293T C174(1.67); C93(1.08)  LDD1049  [2]
 LDCM0452  CL60 PaTu 8988t C174(0.84); C54(0.74)  LDD1331  [2]
 LDCM0453  CL61 PaTu 8988t C589(1.03)  LDD1332  [2]
 LDCM0454  CL62 PaTu 8988t C589(0.83)  LDD1333  [2]
 LDCM0455  CL63 PaTu 8988t C589(0.91)  LDD1334  [2]
 LDCM0456  CL64 PaTu 8988t C589(0.92)  LDD1335  [2]
 LDCM0457  CL65 PaTu 8988t C589(0.97)  LDD1336  [2]
 LDCM0458  CL66 PaTu 8988t C589(1.02)  LDD1337  [2]
 LDCM0459  CL67 PaTu 8988t C589(0.91)  LDD1338  [2]
 LDCM0460  CL68 PaTu 8988t C589(0.84)  LDD1339  [2]
 LDCM0461  CL69 PaTu 8988t C589(0.91)  LDD1340  [2]
 LDCM0462  CL7 HEK-293T C174(1.17); C93(0.94)  LDD1060  [2]
 LDCM0463  CL70 PaTu 8988t C589(0.90)  LDD1342  [2]
 LDCM0464  CL71 PaTu 8988t C589(0.87)  LDD1343  [2]
 LDCM0465  CL72 PaTu 8988t C589(0.92)  LDD1344  [2]
 LDCM0466  CL73 PaTu 8988t C589(1.00)  LDD1345  [2]
 LDCM0467  CL74 PaTu 8988t C589(0.91)  LDD1346  [2]
 LDCM0469  CL76 HEK-293T C93(0.80)  LDD1067  [2]
 LDCM0470  CL77 HEK-293T C93(0.79)  LDD1068  [2]
 LDCM0471  CL78 HEK-293T C93(0.68)  LDD1069  [2]
 LDCM0472  CL79 HEK-293T C93(0.68)  LDD1070  [2]
 LDCM0473  CL8 HEK-293T C174(1.32); C93(1.04)  LDD1071  [2]
 LDCM0474  CL80 HEK-293T C93(0.92)  LDD1072  [2]
 LDCM0475  CL81 HEK-293T C93(0.53)  LDD1073  [2]
 LDCM0476  CL82 HEK-293T C93(0.39)  LDD1074  [2]
 LDCM0477  CL83 HEK-293T C93(0.46)  LDD1075  [2]
 LDCM0478  CL84 HEK-293T C93(0.56)  LDD1076  [2]
 LDCM0479  CL85 HEK-293T C93(1.48)  LDD1077  [2]
 LDCM0480  CL86 HEK-293T C93(1.54)  LDD1078  [2]
 LDCM0481  CL87 HEK-293T C93(0.63)  LDD1079  [2]
 LDCM0482  CL88 HEK-293T C93(0.53)  LDD1080  [2]
 LDCM0483  CL89 HEK-293T C93(0.97)  LDD1081  [2]
 LDCM0484  CL9 HEK-293T C174(1.08); C93(1.01)  LDD1082  [2]
 LDCM0485  CL90 HEK-293T C93(0.44)  LDD1083  [2]
 LDCM0486  CL91 HCT 116 C93(1.02)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C93(0.96)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C93(1.28)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C93(0.93)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C93(1.04)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C93(0.86)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C93(1.00)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C93(1.00)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C93(0.81)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C174(0.78); C589(0.95); C93(0.95)  LDD1698  [4]
 LDCM0468  Fragment33 PaTu 8988t C589(0.83)  LDD1347  [2]
 LDCM0427  Fragment51 HCT 116 C93(0.46)  LDD0744  [2]
 LDCM0022  KB02 HEK-293T C174(0.99); C67(1.06); C589(0.93)  LDD1492  [4]
 LDCM0023  KB03 HEK-293T C174(1.06); C67(1.01); C589(0.95)  LDD1497  [4]
 LDCM0024  KB05 UACC257 C93(2.25)  LDD3325  [5]

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
5 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840