Details of the Target

General Information of Target

Target ID LDTP10009
Target Name Ankyrin repeat and BTB/POZ domain-containing protein 1 (ABTB1)
Gene Name ABTB1
Gene ID 80325
Synonyms
BPOZ; Ankyrin repeat and BTB/POZ domain-containing protein 1; Elongation factor 1A-binding protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGPFRFTPNPEFSTYPPAATEGPNI
VCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLKV
KDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSFF
SNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENAE
DRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRLY
KENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICR
QYVVRAVHVFKS
Target Bioclass
Other
Subcellular location
Cytoplasm
Function May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.
Uniprot ID
Q969K4
Ensemble ID
ENST00000232744.13
HGNC ID
HGNC:18275

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.R431W .
CCK81 Deletion: p.P318QfsTer36 .
CHL1 SNV: p.H286N .
DOTC24510 SNV: p.A356G .
GB1 SNV: p.P231R .
HCC1806 SNV: p.E209Q .
HCT15 SNV: p.Y296C .
HT Deletion: p.E252SfsTer102 .
NCIH2172 SNV: p.R96W .
PF382 SNV: p.M337T .
TOV21G SNV: p.R98L .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C95(9.17)  LDD1704  [1]
DBIA
 Probe Info  		C62(0.96)  LDD0078  [2]
NAIA_4
 Probe Info  		C72(0.00); C222(0.00)  LDD2226  [3]
NAIA_5
 Probe Info  		N.A.  LDD2223  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C95(1.30)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C72(1.04)  LDD0532  [2]
 LDCM0226  AC11 HCT 116 C72(1.02)  LDD0543  [2]
 LDCM0230  AC113 PaTu 8988t C195(1.21)  LDD1109  [2]
 LDCM0231  AC114 PaTu 8988t C195(1.19)  LDD1110  [2]
 LDCM0232  AC115 PaTu 8988t C195(1.04)  LDD1111  [2]
 LDCM0233  AC116 PaTu 8988t C195(1.25)  LDD1112  [2]
 LDCM0234  AC117 PaTu 8988t C195(1.29)  LDD1113  [2]
 LDCM0235  AC118 PaTu 8988t C195(0.98)  LDD1114  [2]
 LDCM0236  AC119 PaTu 8988t C195(0.98)  LDD1115  [2]
 LDCM0237  AC12 HCT 116 C72(0.86)  LDD0554  [2]
 LDCM0238  AC120 PaTu 8988t C195(1.25)  LDD1117  [2]
 LDCM0239  AC121 PaTu 8988t C195(1.14)  LDD1118  [2]
 LDCM0240  AC122 PaTu 8988t C195(1.05)  LDD1119  [2]
 LDCM0241  AC123 PaTu 8988t C195(0.89)  LDD1120  [2]
 LDCM0242  AC124 PaTu 8988t C195(1.26)  LDD1121  [2]
 LDCM0243  AC125 PaTu 8988t C195(1.05)  LDD1122  [2]
 LDCM0244  AC126 PaTu 8988t C195(1.29)  LDD1123  [2]
 LDCM0245  AC127 PaTu 8988t C195(1.18)  LDD1124  [2]
 LDCM0246  AC128 PaTu 8988t C195(1.12)  LDD1125  [2]
 LDCM0247  AC129 PaTu 8988t C195(1.11)  LDD1126  [2]
 LDCM0249  AC130 PaTu 8988t C195(1.21)  LDD1128  [2]
 LDCM0250  AC131 PaTu 8988t C195(1.09)  LDD1129  [2]
 LDCM0251  AC132 PaTu 8988t C195(0.99)  LDD1130  [2]
 LDCM0252  AC133 PaTu 8988t C195(1.19)  LDD1131  [2]
 LDCM0253  AC134 PaTu 8988t C195(1.16)  LDD1132  [2]
 LDCM0254  AC135 PaTu 8988t C195(1.26)  LDD1133  [2]
 LDCM0255  AC136 PaTu 8988t C195(1.17)  LDD1134  [2]
 LDCM0256  AC137 PaTu 8988t C195(1.26)  LDD1135  [2]
 LDCM0257  AC138 PaTu 8988t C195(0.99)  LDD1136  [2]
 LDCM0258  AC139 PaTu 8988t C195(1.22)  LDD1137  [2]
 LDCM0259  AC14 HCT 116 C72(1.16)  LDD0576  [2]
 LDCM0260  AC140 PaTu 8988t C195(1.11)  LDD1139  [2]
 LDCM0261  AC141 PaTu 8988t C195(1.08)  LDD1140  [2]
 LDCM0262  AC142 PaTu 8988t C195(1.00)  LDD1141  [2]
 LDCM0263  AC143 HCT 116 C95(1.28)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C95(2.53)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C95(1.20)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C95(1.64)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C95(1.74)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C95(3.62)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C95(1.84)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C72(0.92)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C95(1.40)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C95(0.90)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C95(1.96)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C95(1.96)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C95(2.12)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C95(1.69)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C95(1.44)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C95(1.38)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C72(1.04)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C72(1.12)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C72(1.08)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C95(1.21)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C72(1.03)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C72(0.81)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C72(1.19)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C72(1.18)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C72(0.89)  LDD0601  [2]
 LDCM0285  AC25 PaTu 8988t C95(0.70)  LDD1164  [2]
 LDCM0286  AC26 PaTu 8988t C95(0.97)  LDD1165  [2]
 LDCM0287  AC27 PaTu 8988t C95(0.83)  LDD1166  [2]
 LDCM0288  AC28 PaTu 8988t C95(0.96)  LDD1167  [2]
 LDCM0289  AC29 PaTu 8988t C95(1.34)  LDD1168  [2]
 LDCM0290  AC3 HCT 116 C95(1.23)  LDD0607  [2]
 LDCM0291  AC30 PaTu 8988t C95(1.15)  LDD1170  [2]
 LDCM0292  AC31 PaTu 8988t C95(0.76)  LDD1171  [2]
 LDCM0293  AC32 PaTu 8988t C95(0.85)  LDD1172  [2]
 LDCM0294  AC33 PaTu 8988t C95(1.06)  LDD1173  [2]
 LDCM0295  AC34 PaTu 8988t C95(1.31)  LDD1174  [2]
 LDCM0296  AC35 HCT 116 C72(0.94)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C72(1.12)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C72(1.07)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C72(0.96)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C72(0.95)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C95(1.22)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C72(0.93)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C72(1.05)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C72(1.02)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C72(1.18)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C72(1.04)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C72(1.08)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C72(1.15)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C72(1.43)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C72(1.29)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C72(2.01)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C95(1.73)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C72(1.49)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C72(1.69)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C72(1.56)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C72(1.20)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C72(1.30)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C72(1.76)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C72(2.02)  LDD0636  [2]
 LDCM0323  AC6 HCT 116 C72(0.91)  LDD0640  [2]
 LDCM0332  AC68 PaTu 8988t C95(1.18); C195(1.11)  LDD1211  [2]
 LDCM0333  AC69 PaTu 8988t C95(1.27); C195(1.22)  LDD1212  [2]
 LDCM0334  AC7 HCT 116 C72(0.91)  LDD0651  [2]
 LDCM0335  AC70 PaTu 8988t C95(1.78); C195(0.96)  LDD1214  [2]
 LDCM0336  AC71 PaTu 8988t C95(1.10); C195(1.04)  LDD1215  [2]
 LDCM0337  AC72 PaTu 8988t C95(1.54); C195(1.04)  LDD1216  [2]
 LDCM0338  AC73 PaTu 8988t C95(1.34); C195(1.08)  LDD1217  [2]
 LDCM0339  AC74 PaTu 8988t C95(1.15); C195(1.05)  LDD1218  [2]
 LDCM0340  AC75 PaTu 8988t C95(1.23); C195(1.01)  LDD1219  [2]
 LDCM0341  AC76 PaTu 8988t C95(1.28); C195(1.05)  LDD1220  [2]
 LDCM0342  AC77 PaTu 8988t C95(1.30); C195(1.00)  LDD1221  [2]
 LDCM0343  AC78 PaTu 8988t C95(1.43); C195(0.98)  LDD1222  [2]
 LDCM0344  AC79 PaTu 8988t C95(1.19); C195(1.06)  LDD1223  [2]
 LDCM0345  AC8 HCT 116 C72(0.95)  LDD0662  [2]
 LDCM0346  AC80 PaTu 8988t C95(1.63); C195(1.08)  LDD1225  [2]
 LDCM0347  AC81 PaTu 8988t C95(1.45); C195(1.20)  LDD1226  [2]
 LDCM0348  AC82 PaTu 8988t C95(1.52); C195(0.96)  LDD1227  [2]
 LDCM0349  AC83 PaTu 8988t C195(1.25)  LDD1228  [2]
 LDCM0350  AC84 PaTu 8988t C195(1.13)  LDD1229  [2]
 LDCM0351  AC85 PaTu 8988t C195(1.48)  LDD1230  [2]
 LDCM0352  AC86 PaTu 8988t C195(1.41)  LDD1231  [2]
 LDCM0353  AC87 PaTu 8988t C195(1.40)  LDD1232  [2]
 LDCM0354  AC88 PaTu 8988t C195(1.45)  LDD1233  [2]
 LDCM0355  AC89 PaTu 8988t C195(1.22)  LDD1234  [2]
 LDCM0357  AC90 PaTu 8988t C195(1.23)  LDD1236  [2]
 LDCM0358  AC91 PaTu 8988t C195(1.27)  LDD1237  [2]
 LDCM0359  AC92 PaTu 8988t C195(1.60)  LDD1238  [2]
 LDCM0360  AC93 PaTu 8988t C195(1.24)  LDD1239  [2]
 LDCM0361  AC94 PaTu 8988t C195(1.47)  LDD1240  [2]
 LDCM0362  AC95 PaTu 8988t C195(1.41)  LDD1241  [2]
 LDCM0363  AC96 PaTu 8988t C195(1.93)  LDD1242  [2]
 LDCM0364  AC97 PaTu 8988t C195(1.34)  LDD1243  [2]
 LDCM0248  AKOS034007472 HCT 116 C72(0.90)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C72(1.13)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C72(1.22)  LDD0592  [2]
 LDCM0020  ARS-1620 HCC44 C62(0.96)  LDD0078  [2]
 LDCM0367  CL1 HCT 116 C95(1.29)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C95(1.62)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C95(1.27)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C72(1.00)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C72(0.90)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C72(1.04)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C72(0.95)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C72(1.08)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C72(0.96)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C72(1.19)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C72(1.06)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C72(1.57)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C95(8.00)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C72(1.08)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C72(1.11)  LDD0698  [2]
 LDCM0382  CL112 PaTu 8988t C95(0.89)  LDD1261  [2]
 LDCM0383  CL113 PaTu 8988t C95(0.67)  LDD1262  [2]
 LDCM0384  CL114 PaTu 8988t C95(0.92)  LDD1263  [2]
 LDCM0385  CL115 PaTu 8988t C95(1.48)  LDD1264  [2]
 LDCM0386  CL116 PaTu 8988t C95(0.82)  LDD1265  [2]
 LDCM0387  CL117 HCT 116 C72(1.07)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C72(1.24)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C72(1.22)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C95(1.88)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C72(1.44)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C72(1.05)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C72(1.26)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C72(0.95)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C72(1.63)  LDD0712  [2]
 LDCM0400  CL13 HCT 116 C95(1.36)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C95(1.72)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C95(1.95)  LDD0719  [2]
 LDCM0403  CL16 PaTu 8988t C95(1.10); C72(0.97)  LDD1282  [2]
 LDCM0404  CL17 PaTu 8988t C95(1.18); C72(1.12)  LDD1283  [2]
 LDCM0405  CL18 PaTu 8988t C95(1.42); C72(1.12)  LDD1284  [2]
 LDCM0406  CL19 PaTu 8988t C95(1.47); C72(0.94)  LDD1285  [2]
 LDCM0407  CL2 HCT 116 C95(1.10)  LDD0724  [2]
 LDCM0408  CL20 PaTu 8988t C95(1.60); C72(0.98)  LDD1287  [2]
 LDCM0409  CL21 PaTu 8988t C95(3.33); C72(1.04)  LDD1288  [2]
 LDCM0410  CL22 PaTu 8988t C95(1.88); C72(1.17)  LDD1289  [2]
 LDCM0411  CL23 PaTu 8988t C95(1.39); C72(1.31)  LDD1290  [2]
 LDCM0412  CL24 PaTu 8988t C95(1.09); C72(1.21)  LDD1291  [2]
 LDCM0413  CL25 PaTu 8988t C95(1.23); C72(1.02)  LDD1292  [2]
 LDCM0414  CL26 PaTu 8988t C95(1.47); C72(1.07)  LDD1293  [2]
 LDCM0415  CL27 PaTu 8988t C95(1.15); C72(1.16)  LDD1294  [2]
 LDCM0416  CL28 PaTu 8988t C95(2.01); C72(0.98)  LDD1295  [2]
 LDCM0417  CL29 PaTu 8988t C95(2.01); C72(1.14)  LDD1296  [2]
 LDCM0418  CL3 HCT 116 C95(1.31)  LDD0735  [2]
 LDCM0419  CL30 PaTu 8988t C95(1.27); C72(1.10)  LDD1298  [2]
 LDCM0420  CL31 HCT 116 C95(1.19); C72(0.78)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C95(1.71); C72(0.86)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C95(5.05); C72(0.91)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C95(1.80); C72(0.81)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C95(1.69); C72(0.78)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C95(1.30); C72(0.90)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C95(1.43); C72(0.91)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C95(2.56); C72(1.02)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C95(1.34)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C95(5.37); C72(0.77)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C95(1.27); C72(0.81)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C95(1.97); C72(1.30)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C95(1.57); C72(0.95)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C95(1.61); C72(0.98)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C95(1.65); C72(1.15)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C72(0.98)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C72(1.00)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C72(0.91)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C72(0.89)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C95(1.22)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C72(0.93)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C72(1.01)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C72(1.03)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C72(0.81)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C72(1.03)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C72(0.97)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C72(0.85)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C72(0.92)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C72(1.05)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C72(1.14)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C95(1.26)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C72(1.21)  LDD0769  [2]
 LDCM0453  CL61 PaTu 8988t C95(1.12); C72(1.03); C195(1.11)  LDD1332  [2]
 LDCM0454  CL62 PaTu 8988t C95(1.08); C72(1.21); C195(1.11)  LDD1333  [2]
 LDCM0455  CL63 PaTu 8988t C95(0.89); C72(1.22); C195(1.13)  LDD1334  [2]
 LDCM0456  CL64 PaTu 8988t C95(1.11); C72(1.46); C195(1.21)  LDD1335  [2]
 LDCM0457  CL65 PaTu 8988t C95(1.23); C72(1.52); C195(1.11)  LDD1336  [2]
 LDCM0458  CL66 PaTu 8988t C95(1.38); C72(1.42); C195(1.16)  LDD1337  [2]
 LDCM0459  CL67 PaTu 8988t C95(1.23); C72(1.22); C195(1.31)  LDD1338  [2]
 LDCM0460  CL68 PaTu 8988t C95(1.86); C72(2.20); C195(1.32)  LDD1339  [2]
 LDCM0461  CL69 PaTu 8988t C95(1.93); C72(1.68); C195(1.19)  LDD1340  [2]
 LDCM0462  CL7 HCT 116 C95(1.31)  LDD0779  [2]
 LDCM0463  CL70 PaTu 8988t C95(1.38); C72(1.49); C195(1.16)  LDD1342  [2]
 LDCM0464  CL71 PaTu 8988t C95(0.92); C72(1.43); C195(1.03)  LDD1343  [2]
 LDCM0465  CL72 PaTu 8988t C95(0.93); C72(1.60); C195(1.01)  LDD1344  [2]
 LDCM0466  CL73 PaTu 8988t C95(1.45); C72(1.74); C195(1.07)  LDD1345  [2]
 LDCM0467  CL74 PaTu 8988t C95(1.13); C72(1.60); C195(1.04)  LDD1346  [2]
 LDCM0469  CL76 HCT 116 C72(0.94)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C72(1.00)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C72(0.94)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C72(0.90)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C95(2.32)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C72(1.16)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C72(1.01)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C72(1.09)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C72(0.98)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C72(1.06)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C72(1.04)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C72(1.11)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C72(0.84)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C72(1.04)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C72(1.02)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C95(2.88)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C72(0.91)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C95(1.27)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C95(1.85)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C95(1.52)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C95(1.27)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C95(1.38)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C95(0.97)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C95(1.29)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C95(2.01)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C95(1.28)  LDD0811  [2]
 LDCM0468  Fragment33 PaTu 8988t C95(1.15); C72(1.21); C195(1.05)  LDD1347  [2]
 LDCM0427  Fragment51 HCT 116 C95(1.64); C72(0.94)  LDD0744  [2]
 LDCM0022  KB02 T cell-activated C95(9.17)  LDD1704  [1]
 LDCM0021  THZ1 HCT 116 C72(1.05); C95(1.07); C62(1.05)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cullin-3 (CUL3) Cullin family Q13618
Elongation factor 1-alpha 2 (EEF1A2) Classic translation factor GTPase family Q05639
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-1 (ATXN1) ATXN1 family P54253
TAR DNA-binding protein 43 (TARDBP) . Q13148

References

1 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264