Details of the Target

General Information of Target

Target ID LDTP08360
Target Name GAS2-like protein 3 (GAS2L3)
Gene Name GAS2L3
Gene ID 283431
Synonyms
GAS2-like protein 3; Growth arrest-specific protein 2-like 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSG
LLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFF
ARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVK
LEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEG
RYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVS
NESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLK
GGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPA
LPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHIS
SRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPS
DGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKT
GPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPS
SVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK
Target Bioclass
Other
Family
GAS2 family
Subcellular location
Cytoplasm
Function Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.
Uniprot ID
Q86XJ1
Ensemble ID
ENST00000266754.9
HGNC ID
HGNC:27475

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C33(5.31)  LDD0170  [1]
IA-alkyne
 Probe Info  		C33(1.12)  LDD2214  [2]
IPM
 Probe Info  		C435(1.20)  LDD1701  [3]
DBIA
 Probe Info  		C132(0.79)  LDD0533  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C33(5.31)  LDD0170  [1]
 LDCM0214  AC1 PaTu 8988t C132(0.71)  LDD1093  [4]
 LDCM0215  AC10 HEK-293T C435(1.05)  LDD1508  [5]
 LDCM0216  AC100 HCT 116 C132(0.79)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C132(0.88)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C132(0.67)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C132(0.74)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C132(0.64)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C132(0.72)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C132(0.72)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C132(0.68)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C132(0.73)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C132(0.75)  LDD0542  [4]
 LDCM0227  AC110 HCT 116 C132(0.74)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C132(0.70)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C132(0.76)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C132(0.85)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C132(0.97)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C132(1.03)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C132(1.09)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C132(1.12)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C132(1.02)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C132(1.05)  LDD0553  [4]
 LDCM0237  AC12 HEK-293T C33(1.13); C427(0.96)  LDD1510  [5]
 LDCM0238  AC120 HCT 116 C132(1.00)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C132(1.08)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C132(0.98)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C132(0.95)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C132(1.10)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C132(0.95)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C132(1.06)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C132(0.92)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C132(1.18)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C132(0.99)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C132(1.14)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C132(1.10)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C132(1.17)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C132(1.23)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C132(1.16)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C132(1.21)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C132(1.21)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C132(1.18)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C132(1.13)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C132(1.15)  LDD0575  [4]
 LDCM0260  AC140 HCT 116 C132(1.27)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C132(1.14)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C132(1.15)  LDD0579  [4]
 LDCM0270  AC15 HEK-293T C33(1.17)  LDD1513  [5]
 LDCM0276  AC17 PaTu 8988t C132(0.82)  LDD1155  [4]
 LDCM0277  AC18 PaTu 8988t C132(0.79)  LDD1156  [4]
 LDCM0278  AC19 PaTu 8988t C132(0.91)  LDD1157  [4]
 LDCM0279  AC2 PaTu 8988t C132(0.75)  LDD1158  [4]
 LDCM0280  AC20 PaTu 8988t C132(0.79)  LDD1159  [4]
 LDCM0281  AC21 PaTu 8988t C132(0.83)  LDD1160  [4]
 LDCM0282  AC22 PaTu 8988t C132(0.83)  LDD1161  [4]
 LDCM0283  AC23 PaTu 8988t C132(0.78)  LDD1162  [4]
 LDCM0284  AC24 PaTu 8988t C132(0.82)  LDD1163  [4]
 LDCM0285  AC25 PaTu 8988t C33(0.95); C132(1.23)  LDD1164  [4]
 LDCM0286  AC26 PaTu 8988t C33(1.32); C132(0.89)  LDD1165  [4]
 LDCM0287  AC27 PaTu 8988t C33(1.64); C132(0.82)  LDD1166  [4]
 LDCM0288  AC28 PaTu 8988t C33(1.41); C132(0.92)  LDD1167  [4]
 LDCM0289  AC29 PaTu 8988t C33(1.08); C132(1.06)  LDD1168  [4]
 LDCM0290  AC3 PaTu 8988t C132(0.68)  LDD1169  [4]
 LDCM0291  AC30 PaTu 8988t C33(0.83); C132(0.99)  LDD1170  [4]
 LDCM0292  AC31 PaTu 8988t C33(0.98); C132(0.95)  LDD1171  [4]
 LDCM0293  AC32 PaTu 8988t C33(0.98); C132(0.86)  LDD1172  [4]
 LDCM0294  AC33 PaTu 8988t C33(1.66); C132(0.97)  LDD1173  [4]
 LDCM0295  AC34 PaTu 8988t C33(1.03); C132(0.92)  LDD1174  [4]
 LDCM0296  AC35 PaTu 8988t C33(1.40); C132(0.85)  LDD1175  [4]
 LDCM0297  AC36 PaTu 8988t C33(1.68); C132(0.84)  LDD1176  [4]
 LDCM0298  AC37 PaTu 8988t C33(1.73); C132(0.83)  LDD1177  [4]
 LDCM0299  AC38 PaTu 8988t C33(2.27); C132(0.91)  LDD1178  [4]
 LDCM0300  AC39 PaTu 8988t C33(1.89); C132(0.86)  LDD1179  [4]
 LDCM0301  AC4 PaTu 8988t C132(0.93)  LDD1180  [4]
 LDCM0302  AC40 PaTu 8988t C33(1.77); C132(0.80)  LDD1181  [4]
 LDCM0303  AC41 PaTu 8988t C33(1.12); C132(0.81)  LDD1182  [4]
 LDCM0304  AC42 PaTu 8988t C33(1.42); C132(0.80)  LDD1183  [4]
 LDCM0305  AC43 PaTu 8988t C33(1.63); C132(0.83)  LDD1184  [4]
 LDCM0306  AC44 PaTu 8988t C33(1.68); C132(0.89)  LDD1185  [4]
 LDCM0307  AC45 PaTu 8988t C33(1.43); C132(0.74)  LDD1186  [4]
 LDCM0308  AC46 HCT 116 C132(1.16)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C132(1.10)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C132(1.10)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C132(1.00)  LDD0628  [4]
 LDCM0312  AC5 PaTu 8988t C132(0.79)  LDD1191  [4]
 LDCM0313  AC50 HCT 116 C132(0.96)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C132(0.87)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C132(0.95)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C132(0.90)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C132(0.92)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C132(1.27)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C132(1.06)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C132(0.84)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C132(0.90)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C132(0.86)  LDD0639  [4]
 LDCM0324  AC60 HCT 116 C132(0.89)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C132(0.78)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C132(0.75)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C132(0.81)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C132(0.86)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C132(0.81)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C132(0.86)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C132(0.75)  LDD0648  [4]
 LDCM0332  AC68 PaTu 8988t C132(0.83)  LDD1211  [4]
 LDCM0333  AC69 PaTu 8988t C132(0.94)  LDD1212  [4]
 LDCM0334  AC7 HEK-293T C33(1.24)  LDD1568  [5]
 LDCM0335  AC70 PaTu 8988t C132(0.86)  LDD1214  [4]
 LDCM0336  AC71 PaTu 8988t C132(0.80)  LDD1215  [4]
 LDCM0337  AC72 PaTu 8988t C132(1.10)  LDD1216  [4]
 LDCM0338  AC73 PaTu 8988t C132(0.99)  LDD1217  [4]
 LDCM0339  AC74 PaTu 8988t C132(1.04)  LDD1218  [4]
 LDCM0340  AC75 PaTu 8988t C132(0.74)  LDD1219  [4]
 LDCM0341  AC76 PaTu 8988t C132(0.95)  LDD1220  [4]
 LDCM0342  AC77 PaTu 8988t C132(0.93)  LDD1221  [4]
 LDCM0343  AC78 PaTu 8988t C132(0.83)  LDD1222  [4]
 LDCM0344  AC79 PaTu 8988t C132(0.87)  LDD1223  [4]
 LDCM0346  AC80 PaTu 8988t C132(0.95)  LDD1225  [4]
 LDCM0347  AC81 PaTu 8988t C132(1.00)  LDD1226  [4]
 LDCM0348  AC82 PaTu 8988t C132(0.98)  LDD1227  [4]
 LDCM0349  AC83 HCT 116 C132(1.05)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C132(1.00)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C132(0.97)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C132(1.14)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C132(1.20)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C132(1.20)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C132(0.92)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C132(1.06)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C132(1.01)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C132(1.03)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C132(0.94)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C132(0.90)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C132(0.93)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C132(1.01)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C132(1.01)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C132(0.75)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C132(0.83)  LDD0683  [4]
 LDCM0248  AKOS034007472 HEK-293T C33(1.01)  LDD1511  [5]
 LDCM0630  CCW28-3 231MFP C33(1.12)  LDD2214  [2]
 LDCM0367  CL1 PaTu 8988t C132(0.77)  LDD1246  [4]
 LDCM0368  CL10 PaTu 8988t C132(0.52)  LDD1247  [4]
 LDCM0369  CL100 PaTu 8988t C132(0.72)  LDD1248  [4]
 LDCM0370  CL101 HEK-293T C33(1.20)  LDD1574  [5]
 LDCM0371  CL102 HEK-293T C33(1.22); C435(1.01)  LDD1575  [5]
 LDCM0372  CL103 HEK-293T C435(1.07)  LDD1576  [5]
 LDCM0373  CL104 HEK-293T C33(0.88); C435(1.06)  LDD1577  [5]
 LDCM0374  CL105 PaTu 8988t C132(0.86)  LDD1253  [4]
 LDCM0375  CL106 PaTu 8988t C132(0.82)  LDD1254  [4]
 LDCM0376  CL107 PaTu 8988t C132(0.92)  LDD1255  [4]
 LDCM0377  CL108 PaTu 8988t C132(0.75)  LDD1256  [4]
 LDCM0378  CL109 PaTu 8988t C132(0.84)  LDD1257  [4]
 LDCM0379  CL11 PaTu 8988t C132(0.55)  LDD1258  [4]
 LDCM0380  CL110 PaTu 8988t C132(0.72)  LDD1259  [4]
 LDCM0381  CL111 PaTu 8988t C132(0.73)  LDD1260  [4]
 LDCM0382  CL112 PaTu 8988t C33(1.09); C132(1.22)  LDD1261  [4]
 LDCM0383  CL113 PaTu 8988t C33(1.11); C132(1.16)  LDD1262  [4]
 LDCM0384  CL114 PaTu 8988t C33(1.06); C132(0.79)  LDD1263  [4]
 LDCM0385  CL115 PaTu 8988t C33(0.95); C132(1.01)  LDD1264  [4]
 LDCM0386  CL116 PaTu 8988t C33(1.08); C132(0.87)  LDD1265  [4]
 LDCM0387  CL117 PaTu 8988t C33(1.22); C132(0.70)  LDD1266  [4]
 LDCM0388  CL118 PaTu 8988t C33(1.21); C132(0.73)  LDD1267  [4]
 LDCM0389  CL119 PaTu 8988t C33(1.66); C132(0.76)  LDD1268  [4]
 LDCM0390  CL12 PaTu 8988t C132(0.65)  LDD1269  [4]
 LDCM0391  CL120 PaTu 8988t C33(1.59); C132(0.81)  LDD1270  [4]
 LDCM0392  CL121 HCT 116 C132(1.10)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C132(1.03)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C132(1.11)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C132(1.26)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C132(0.82)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C132(0.81)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C132(0.87)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C132(0.96)  LDD0716  [4]
 LDCM0400  CL13 PaTu 8988t C132(0.52)  LDD1279  [4]
 LDCM0401  CL14 PaTu 8988t C132(0.54)  LDD1280  [4]
 LDCM0402  CL15 PaTu 8988t C132(0.58)  LDD1281  [4]
 LDCM0403  CL16 HEK-293T C33(1.04); C435(1.25)  LDD1607  [5]
 LDCM0405  CL18 HEK-293T C435(1.02)  LDD1609  [5]
 LDCM0407  CL2 PaTu 8988t C132(0.47)  LDD1286  [4]
 LDCM0408  CL20 HEK-293T C33(1.88); C427(0.96)  LDD1612  [5]
 LDCM0409  CL21 HEK-293T C33(1.98)  LDD1613  [5]
 LDCM0411  CL23 HEK-293T C33(1.58)  LDD1615  [5]
 LDCM0413  CL25 HEK-293T C33(1.24)  LDD1617  [5]
 LDCM0414  CL26 HEK-293T C33(1.14); C435(0.93)  LDD1618  [5]
 LDCM0415  CL27 HEK-293T C435(1.10)  LDD1619  [5]
 LDCM0416  CL28 HEK-293T C33(1.06); C435(1.11)  LDD1620  [5]
 LDCM0418  CL3 PaTu 8988t C132(0.59)  LDD1297  [4]
 LDCM0419  CL30 HEK-293T C435(0.90)  LDD1623  [5]
 LDCM0420  CL31 HCT 116 C132(0.82)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C132(0.98)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C132(0.83)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C132(0.93)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C132(0.89)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C132(0.88)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C132(0.90)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C132(0.96)  LDD0745  [4]
 LDCM0429  CL4 PaTu 8988t C132(0.77)  LDD1308  [4]
 LDCM0430  CL40 HCT 116 C132(0.87)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C132(0.87)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C132(1.03)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C132(0.99)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C132(0.89)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C132(1.02)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C132(0.93)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C132(0.94)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C132(0.90)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C132(0.94)  LDD0756  [4]
 LDCM0440  CL5 PaTu 8988t C132(0.56)  LDD1319  [4]
 LDCM0441  CL50 HCT 116 C132(0.87)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C132(1.08)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C132(1.05)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C132(0.93)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C132(0.92)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C132(0.93)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C132(0.81)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C132(1.03)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C132(1.02)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C132(1.01)  LDD0767  [4]
 LDCM0451  CL6 PaTu 8988t C132(0.63)  LDD1330  [4]
 LDCM0452  CL60 HCT 116 C132(0.91)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C132(0.94)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C132(0.86)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C132(0.76)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C132(0.89)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C132(0.98)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C132(0.89)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C132(0.92)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C132(0.83)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C132(1.04)  LDD0778  [4]
 LDCM0462  CL7 PaTu 8988t C132(0.60)  LDD1341  [4]
 LDCM0463  CL70 HCT 116 C132(0.89)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C132(0.80)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C132(0.92)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C132(0.96)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C132(0.89)  LDD0784  [4]
 LDCM0469  CL76 PaTu 8988t C132(0.88)  LDD1348  [4]
 LDCM0470  CL77 PaTu 8988t C132(0.77)  LDD1349  [4]
 LDCM0471  CL78 PaTu 8988t C132(0.74)  LDD1350  [4]
 LDCM0472  CL79 PaTu 8988t C132(0.88)  LDD1351  [4]
 LDCM0473  CL8 PaTu 8988t C132(0.62)  LDD1352  [4]
 LDCM0474  CL80 PaTu 8988t C132(0.82)  LDD1353  [4]
 LDCM0475  CL81 PaTu 8988t C132(0.87)  LDD1354  [4]
 LDCM0476  CL82 PaTu 8988t C132(0.76)  LDD1355  [4]
 LDCM0477  CL83 PaTu 8988t C132(0.80)  LDD1356  [4]
 LDCM0478  CL84 PaTu 8988t C132(0.95)  LDD1357  [4]
 LDCM0479  CL85 PaTu 8988t C132(0.77)  LDD1358  [4]
 LDCM0480  CL86 PaTu 8988t C132(0.77)  LDD1359  [4]
 LDCM0481  CL87 PaTu 8988t C132(0.87)  LDD1360  [4]
 LDCM0482  CL88 PaTu 8988t C132(0.78)  LDD1361  [4]
 LDCM0483  CL89 PaTu 8988t C132(0.90)  LDD1362  [4]
 LDCM0484  CL9 PaTu 8988t C132(0.70)  LDD1363  [4]
 LDCM0485  CL90 PaTu 8988t C132(0.75)  LDD1364  [4]
 LDCM0486  CL91 PaTu 8988t C132(0.73)  LDD1365  [4]
 LDCM0487  CL92 PaTu 8988t C132(0.70)  LDD1366  [4]
 LDCM0488  CL93 PaTu 8988t C132(0.68)  LDD1367  [4]
 LDCM0489  CL94 PaTu 8988t C132(0.76)  LDD1368  [4]
 LDCM0490  CL95 PaTu 8988t C132(0.75)  LDD1369  [4]
 LDCM0491  CL96 PaTu 8988t C132(0.73)  LDD1370  [4]
 LDCM0492  CL97 PaTu 8988t C132(0.71)  LDD1371  [4]
 LDCM0493  CL98 PaTu 8988t C132(0.72)  LDD1372  [4]
 LDCM0494  CL99 PaTu 8988t C132(0.65)  LDD1373  [4]
 LDCM0495  E2913 HEK-293T C435(1.00)  LDD1698  [5]
 LDCM0468  Fragment33 HCT 116 C132(0.87)  LDD0785  [4]
 LDCM0427  Fragment51 HCT 116 C132(0.89)  LDD0744  [4]
 LDCM0022  KB02 769-P C435(1.78)  LDD2246  [6]
 LDCM0023  KB03 MDA-MB-231 C435(1.20)  LDD1701  [3]
 LDCM0024  KB05 NCI-N87 C435(2.13)  LDD3364  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Aurora kinase B (AURKB) Ser/Thr protein kinase family Q96GD4
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein ZIC 1 (ZIC1) GLI C2H2-type zinc-finger protein family Q15915
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Borealin (CDCA8) Borealin family Q53HL2
Baculoviral IAP repeat-containing protein 5 (BIRC5) IAP family O15392
Pre-rRNA-processing protein TSR2 homolog (TSR2) TSR2 family Q969E8
Myosin light polypeptide 6 (MYL6) . P60660

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840