Details of the Target

General Information of Target

Target ID LDTP07425
Target Name DENN domain-containing protein 5A (DENND5A)
Gene Name DENND5A
Gene ID 23258
Synonyms
KIAA1091; RAB6IP1; DENN domain-containing protein 5A; Rab6-interacting protein 1; Rab6IP1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTE
GENFEQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAF
IITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPPADDRDQSSMEDG
EDTPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPL
ESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQ
LFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYL
MGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGI
PPEGNLHCSESASKLKRLRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTG
VSLEKLEVREDPSSNKDLKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQ
DKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPV
LRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKI
GQGKYEPGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYI
QEARTMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHG
EVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTS
GILLDSERRKSDASSLMPPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRH
LKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILI
VPSKKLGGSMFTANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGL
YAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERPCRTP
PLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGE
CGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEKNEVVPEENWHTRARNFCR
FVTAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLV
NSLIRVLQTLQEFNITLETSLVKGIDI
Target Bioclass
Other
Family
RAB6IP1 family
Subcellular location
Golgi apparatus membrane
Function
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth.
Uniprot ID
Q6IQ26
Ensemble ID
ENST00000328194.8
HGNC ID
HGNC:19344

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CORL88 SNV: p.I1166V .
DU145 SNV: p.R993M .
HUH28 SNV: p.L331F .
KMCH1 SNV: p.H820L .
MCC13 SNV: p.R172K; p.P671S .
MELJUSO SNV: p.T28S; p.G29V .
MOLT4 Deletion: p.G968AfsTer29
SNV: .		 .
SNU1 SNV: p.C944R .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C271(0.99)  LDD0531  [1]
IPM
 Probe Info  		N.A.  LDD2156  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C271(0.99)  LDD0531  [1]
 LDCM0215  AC10 HEK-293T C502(1.08); C629(1.02)  LDD1508  [3]
 LDCM0226  AC11 HEK-293T C502(1.06); C629(1.03)  LDD1509  [3]
 LDCM0230  AC113 HEK-293T C271(0.87)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C271(1.17)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C271(1.15)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C271(1.10)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C271(1.10)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C271(1.00)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C271(1.32)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C502(1.14); C629(1.12)  LDD1510  [3]
 LDCM0238  AC120 HEK-293T C271(1.10)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C271(1.08)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C271(1.09)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C271(1.18)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C271(1.03)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C271(1.14)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C271(1.20)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C271(1.13)  LDD0843  [1]
 LDCM0259  AC14 HEK-293T C502(0.85)  LDD1512  [3]
 LDCM0263  AC143 HCT 116 C271(0.94)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C271(1.31)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C271(1.55)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C271(1.22)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C271(1.52)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C271(1.27)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C271(1.21)  LDD0586  [1]
 LDCM0270  AC15 HEK-293T C502(1.02); C629(0.99)  LDD1513  [3]
 LDCM0271  AC150 HCT 116 C271(1.00)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C271(1.41)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C271(1.33)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C271(1.57)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C271(1.35)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C271(1.28)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C271(1.02)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C271(1.62)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C271(1.05)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C271(1.12)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C271(1.33)  LDD0595  [1]
 LDCM0279  AC2 HCT 116 C271(0.91)  LDD0596  [1]
 LDCM0280  AC20 HCT 116 C271(0.96)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C271(1.10)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C271(1.25)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C271(1.06)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C271(0.95)  LDD0601  [1]
 LDCM0285  AC25 HEK-293T C502(0.98); C629(1.07)  LDD1524  [3]
 LDCM0286  AC26 HEK-293T C502(1.05); C629(0.85)  LDD1525  [3]
 LDCM0287  AC27 HEK-293T C502(1.15); C629(0.99)  LDD1526  [3]
 LDCM0288  AC28 HEK-293T C502(0.93); C629(1.12)  LDD1527  [3]
 LDCM0289  AC29 HEK-293T C502(1.23)  LDD1528  [3]
 LDCM0290  AC3 HCT 116 C271(1.08)  LDD0607  [1]
 LDCM0291  AC30 HEK-293T C502(0.95)  LDD1530  [3]
 LDCM0292  AC31 HEK-293T C502(1.14); C629(1.43)  LDD1531  [3]
 LDCM0293  AC32 HEK-293T C502(0.94)  LDD1532  [3]
 LDCM0294  AC33 HEK-293T C502(1.06); C629(1.15)  LDD1533  [3]
 LDCM0295  AC34 HEK-293T C502(1.01); C629(1.04)  LDD1534  [3]
 LDCM0296  AC35 HCT 116 C271(0.94)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C271(0.84)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C271(0.90)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C271(0.86)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C271(1.15)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C271(0.93)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C271(0.89)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C271(0.94)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C271(1.05)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C271(0.83)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C271(0.81)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C271(0.84)  LDD0624  [1]
 LDCM0308  AC46 HEK-293T C502(0.92)  LDD1547  [3]
 LDCM0309  AC47 HEK-293T C502(0.94); C629(1.15)  LDD1548  [3]
 LDCM0310  AC48 HEK-293T C502(1.00)  LDD1549  [3]
 LDCM0311  AC49 HEK-293T C502(0.90); C629(1.22)  LDD1550  [3]
 LDCM0312  AC5 HCT 116 C271(0.97)  LDD0629  [1]
 LDCM0313  AC50 HEK-293T C502(1.01); C629(1.07)  LDD1552  [3]
 LDCM0314  AC51 HEK-293T C502(0.91); C629(1.03)  LDD1553  [3]
 LDCM0315  AC52 HEK-293T C502(0.92); C629(1.42)  LDD1554  [3]
 LDCM0316  AC53 HEK-293T C502(0.95)  LDD1555  [3]
 LDCM0317  AC54 HEK-293T C502(1.02)  LDD1556  [3]
 LDCM0318  AC55 HEK-293T C502(0.96); C629(1.03)  LDD1557  [3]
 LDCM0319  AC56 HEK-293T C502(0.81)  LDD1558  [3]
 LDCM0320  AC57 HEK-293T C502(0.89); C629(1.07)  LDD1559  [3]
 LDCM0321  AC58 HEK-293T C502(1.13); C629(1.13)  LDD1560  [3]
 LDCM0322  AC59 HEK-293T C502(1.13); C629(0.97)  LDD1561  [3]
 LDCM0323  AC6 HEK-293T C502(0.97)  LDD1562  [3]
 LDCM0324  AC60 HEK-293T C502(0.89); C629(0.89)  LDD1563  [3]
 LDCM0325  AC61 HEK-293T C502(1.34)  LDD1564  [3]
 LDCM0326  AC62 HEK-293T C502(1.10)  LDD1565  [3]
 LDCM0327  AC63 HEK-293T C502(1.17); C629(1.10)  LDD1566  [3]
 LDCM0328  AC64 HEK-293T C502(0.88)  LDD1567  [3]
 LDCM0332  AC68 HCT 116 C271(0.59)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C271(0.70)  LDD0650  [1]
 LDCM0334  AC7 HEK-293T C502(1.11); C629(0.94)  LDD1568  [3]
 LDCM0335  AC70 HCT 116 C271(0.79)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C271(0.66)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C271(0.80)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C271(0.91)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C271(0.81)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C271(0.79)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C271(0.75)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C271(0.60)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C271(0.67)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C271(0.74)  LDD0661  [1]
 LDCM0345  AC8 HEK-293T C502(1.08)  LDD1569  [3]
 LDCM0346  AC80 HCT 116 C271(0.63)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C271(0.72)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C271(0.62)  LDD0665  [1]
 LDCM0248  AKOS034007472 HEK-293T C502(1.32)  LDD1511  [3]
 LDCM0356  AKOS034007680 HEK-293T C502(0.86); C629(1.06)  LDD1570  [3]
 LDCM0275  AKOS034007705 HEK-293T C502(0.80)  LDD1514  [3]
 LDCM0367  CL1 HCT 116 C271(0.76)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C271(0.72)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C271(0.90)  LDD0686  [1]
 LDCM0370  CL101 HEK-293T C502(0.86); C629(0.94); C39(1.00)  LDD1574  [3]
 LDCM0371  CL102 HEK-293T C502(1.25); C629(0.94); C39(1.21)  LDD1575  [3]
 LDCM0372  CL103 HEK-293T C502(1.15)  LDD1576  [3]
 LDCM0373  CL104 HEK-293T C502(0.94); C39(1.06)  LDD1577  [3]
 LDCM0374  CL105 HCT 116 C271(1.01)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C271(1.10)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C271(1.21)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C271(0.98)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C271(1.16)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C271(0.76)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C271(1.16)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C271(1.13)  LDD0698  [1]
 LDCM0382  CL112 HEK-293T C502(0.88); C39(0.86)  LDD1586  [3]
 LDCM0383  CL113 HEK-293T C502(0.98); C629(0.92); C39(1.10)  LDD1587  [3]
 LDCM0384  CL114 HEK-293T C502(1.00); C629(0.80); C39(1.04)  LDD1588  [3]
 LDCM0385  CL115 HEK-293T C502(1.28)  LDD1589  [3]
 LDCM0386  CL116 HEK-293T C502(0.74); C39(0.93)  LDD1590  [3]
 LDCM0387  CL117 HCT 116 C271(0.73)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C271(0.97)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C271(0.93)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C271(0.81)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C271(0.90)  LDD0708  [1]
 LDCM0392  CL121 HEK-293T C502(0.97); C629(1.21); C39(0.95)  LDD1596  [3]
 LDCM0393  CL122 HEK-293T C502(1.15); C629(0.95); C39(0.83)  LDD1597  [3]
 LDCM0394  CL123 HEK-293T C502(1.20)  LDD1598  [3]
 LDCM0395  CL124 HEK-293T C502(1.01); C39(1.01)  LDD1599  [3]
 LDCM0396  CL125 HEK-293T C502(0.81); C629(0.89); C39(0.97)  LDD1600  [3]
 LDCM0397  CL126 HEK-293T C502(1.02); C629(0.82); C39(1.11)  LDD1601  [3]
 LDCM0398  CL127 HEK-293T C502(1.20)  LDD1602  [3]
 LDCM0399  CL128 HEK-293T C502(0.90); C39(0.88)  LDD1603  [3]
 LDCM0400  CL13 HCT 116 C271(0.77)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C271(0.81)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C271(0.90)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C271(0.86)  LDD0720  [1]
 LDCM0404  CL17 HEK-293T C502(0.93); C629(1.21)  LDD1608  [3]
 LDCM0405  CL18 HEK-293T C502(1.11); C629(1.18)  LDD1609  [3]
 LDCM0406  CL19 HEK-293T C502(1.12); C629(1.31)  LDD1610  [3]
 LDCM0407  CL2 HCT 116 C271(0.72)  LDD0724  [1]
 LDCM0408  CL20 HEK-293T C502(1.13); C629(1.18)  LDD1612  [3]
 LDCM0409  CL21 HEK-293T C502(1.38)  LDD1613  [3]
 LDCM0410  CL22 HEK-293T C502(1.19)  LDD1614  [3]
 LDCM0411  CL23 HEK-293T C502(1.21); C629(1.50)  LDD1615  [3]
 LDCM0412  CL24 HEK-293T C502(0.98)  LDD1616  [3]
 LDCM0413  CL25 HEK-293T C502(1.21); C629(1.05); C39(0.84)  LDD1617  [3]
 LDCM0414  CL26 HEK-293T C502(1.16); C629(0.88); C39(0.86)  LDD1618  [3]
 LDCM0415  CL27 HEK-293T C502(1.14)  LDD1619  [3]
 LDCM0416  CL28 HEK-293T C502(1.10); C39(1.06)  LDD1620  [3]
 LDCM0417  CL29 HEK-293T C502(0.95); C629(1.28)  LDD1621  [3]
 LDCM0418  CL3 HCT 116 C271(0.70)  LDD0735  [1]
 LDCM0419  CL30 HEK-293T C502(1.21); C629(0.95)  LDD1623  [3]
 LDCM0420  CL31 HEK-293T C502(0.95); C629(1.22)  LDD1624  [3]
 LDCM0421  CL32 HCT 116 C271(0.86)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C271(0.87)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C271(0.92)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C271(1.00)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C271(1.02)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C271(1.13)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C271(0.92)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C271(0.79)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C271(0.94)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C271(0.94)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C271(0.82)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C271(0.90)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C271(1.01)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C271(0.95)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C271(0.93)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C271(1.20)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C271(0.99)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C271(1.06)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C271(0.84)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C271(0.88)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C271(0.84)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C271(1.03)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C271(1.11)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C271(0.95)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C271(1.03)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C271(1.14)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C271(1.00)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C271(1.18)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C271(1.12)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C271(0.83)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C271(1.04)  LDD0769  [1]
 LDCM0453  CL61 HEK-293T C271(1.15)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C271(1.16)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C271(1.35)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C271(1.44)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C271(1.11)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C271(1.25)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C271(1.00)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C271(0.99)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C271(1.17)  LDD1059  [1]
 LDCM0462  CL7 HCT 116 C271(0.78)  LDD0779  [1]
 LDCM0463  CL70 HEK-293T C271(1.08)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C271(1.16)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C271(1.29)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C271(1.08)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C271(1.30)  LDD1065  [1]
 LDCM0469  CL76 HCT 116 C271(0.78)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C271(1.28)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C271(0.77)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C271(0.91)  LDD0789  [1]
 LDCM0473  CL8 HCT 116 C271(0.82)  LDD0790  [1]
 LDCM0474  CL80 HCT 116 C271(0.78)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C271(0.91)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C271(0.72)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C271(0.74)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C271(0.80)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C271(0.74)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C271(0.69)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C271(0.75)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C271(0.76)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C271(0.92)  LDD0800  [1]
 LDCM0484  CL9 HCT 116 C271(0.81)  LDD0801  [1]
 LDCM0485  CL90 HCT 116 C271(0.84)  LDD0802  [1]
 LDCM0486  CL91 HCT 116 C271(1.07)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C271(0.84)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C271(0.99)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C271(0.92)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C271(0.88)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C271(0.95)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C271(1.06)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C271(1.00)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C271(0.92)  LDD0811  [1]
 LDCM0495  E2913 HEK-293T C502(1.07)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C271(1.23)  LDD1066  [1]
 LDCM0427  Fragment51 HCT 116 C271(0.86)  LDD0744  [1]
 LDCM0022  KB02 PANC-1 C591(1.33)  LDD2558  [4]
 LDCM0023  KB03 PANC-1 C591(1.46)  LDD2975  [4]
 LDCM0024  KB05 PANC-1 C591(1.54)  LDD3392  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840