Details of the Target

General Information of Target

Target ID LDTP03296
Target Name G1/S-specific cyclin-E1 (CCNE1)
Gene Name CCNE1
Gene ID 898
Synonyms
CCNE; G1/S-specific cyclin-E1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ
PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM
LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ
ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR
LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA
ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI
QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
Target Type
Literature-reported
Target Bioclass
Other
Family
Cyclin family, Cyclin E subfamily
Subcellular location
Nucleus
Function Essential for the control of the cell cycle at the G1/S (start) transition.
TTD ID
T10052
Uniprot ID
P24864
DrugMap ID
TTCEJ4F
Ensemble ID
ENST00000262643.8
HGNC ID
HGNC:1589
ChEMBL ID
CHEMBL3617

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL51 SNV: p.T91M .
KMRC1 SNV: p.H211Y .
NCIH23 SNV: p.D83N .
UMUC3 SNV: p.H306Y .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C322(1.06)  LDD0532  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C327(0.22); C322(0.22)  LDD1093  [1]
 LDCM0215  AC10 HCT 116 C322(1.06)  LDD0532  [1]
 LDCM0226  AC11 HCT 116 C322(1.42)  LDD0543  [1]
 LDCM0237  AC12 HCT 116 C322(1.17)  LDD0554  [1]
 LDCM0259  AC14 HCT 116 C322(1.46)  LDD0576  [1]
 LDCM0263  AC143 HCT 116 C322(0.94); C327(0.98)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C327(0.76); C322(0.91)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C327(1.00); C322(1.09)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C327(0.94); C322(1.03)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C327(0.81); C322(0.95)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C322(0.91); C327(0.95)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C327(0.86); C322(0.99)  LDD0586  [1]
 LDCM0270  AC15 HCT 116 C322(1.29)  LDD0587  [1]
 LDCM0271  AC150 HCT 116 C327(0.73); C322(0.86)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C327(0.99); C322(1.08)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C327(0.95); C322(1.08)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C327(0.94); C322(1.06)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C322(1.15); C327(1.10)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C322(0.91); C327(0.84)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C322(1.01); C327(1.01)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C322(1.44); C327(1.30)  LDD2161  [1]
 LDCM0276  AC17 HCT 116 C322(1.06)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C322(1.00)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C322(0.99)  LDD0595  [1]
 LDCM0279  AC2 PaTu 8988t C327(0.30); C322(0.30)  LDD1158  [1]
 LDCM0280  AC20 HCT 116 C322(1.01)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C322(0.87)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C322(0.99)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C322(0.85)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C322(0.96)  LDD0601  [1]
 LDCM0290  AC3 PaTu 8988t C327(0.21); C322(0.21)  LDD1169  [1]
 LDCM0296  AC35 HCT 116 C322(0.78)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C322(0.88)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C322(0.83)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C322(0.84)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C322(0.79)  LDD0617  [1]
 LDCM0301  AC4 PaTu 8988t C327(0.29); C322(0.29)  LDD1180  [1]
 LDCM0302  AC40 HCT 116 C322(0.83)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C322(1.00)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C322(1.03)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C322(1.53)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C322(0.73)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C322(0.81)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C327(0.88); C322(0.92)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C322(1.01); C327(1.08)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C327(0.82); C322(0.86)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C327(0.84); C322(0.95)  LDD0628  [1]
 LDCM0312  AC5 PaTu 8988t C327(0.28); C322(0.28)  LDD1191  [1]
 LDCM0313  AC50 HCT 116 C327(0.80); C322(0.88)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C327(0.94); C322(0.98)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C327(0.93); C322(0.95)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C327(0.90); C322(0.94)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C322(1.06); C327(1.10)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C327(0.87); C322(0.93)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C327(0.79); C322(0.86)  LDD0636  [1]
 LDCM0320  AC57 HCT 116 C327(0.79); C322(0.87)  LDD0637  [1]
 LDCM0321  AC58 HCT 116 C327(0.58); C322(0.85)  LDD0638  [1]
 LDCM0322  AC59 HCT 116 C327(0.72); C322(0.89)  LDD0639  [1]
 LDCM0323  AC6 HCT 116 C322(0.93)  LDD0640  [1]
 LDCM0324  AC60 HCT 116 C327(0.52); C322(0.86)  LDD0641  [1]
 LDCM0325  AC61 HCT 116 C327(0.53); C322(0.79)  LDD0642  [1]
 LDCM0326  AC62 HCT 116 C327(0.66); C322(0.89)  LDD0643  [1]
 LDCM0327  AC63 HCT 116 C327(0.57); C322(0.86)  LDD0644  [1]
 LDCM0328  AC64 HCT 116 C327(0.62); C322(0.87)  LDD0645  [1]
 LDCM0329  AC65 HCT 116 C327(0.64); C322(0.90)  LDD0646  [1]
 LDCM0330  AC66 HCT 116 C327(0.74); C322(0.98)  LDD0647  [1]
 LDCM0331  AC67 HCT 116 C327(0.54); C322(0.81)  LDD0648  [1]
 LDCM0332  AC68 HCT 116 C327(0.97); C322(1.04)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C322(0.92); C327(0.94)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C322(1.21)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C327(0.81); C322(0.92)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C322(1.01); C327(1.22)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C327(0.74); C322(0.96)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C327(0.79); C322(0.95)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C322(0.86); C327(0.92)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C327(0.90); C322(0.97)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C327(0.69); C322(0.83)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C327(1.00); C322(1.11)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C322(0.94); C327(0.97)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C327(0.85); C322(0.88)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C322(0.97)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C322(0.97); C327(1.20)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C322(0.95); C327(1.21)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C327(0.88); C322(1.07)  LDD0665  [1]
 LDCM0349  AC83 HCT 116 C322(1.23)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C322(0.99)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C322(1.07)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C322(1.11)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C322(0.98)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C322(1.03)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C322(1.07)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C322(1.06)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C322(1.11)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C322(1.14)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C322(1.21)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C322(0.86)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C322(1.18)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C322(1.04)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C322(1.12)  LDD0681  [1]
 LDCM0248  AKOS034007472 HCT 116 C322(1.18)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C322(1.32)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C322(0.86)  LDD0592  [1]
 LDCM0367  CL1 HCT 116 C322(2.08); C327(2.08)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C322(0.81); C327(0.81)  LDD0685  [1]
 LDCM0369  CL100 PaTu 8988t C327(0.24); C322(0.24)  LDD1248  [1]
 LDCM0370  CL101 HCT 116 C322(1.44)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C322(1.43)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C322(1.31)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C322(1.13)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C322(0.88)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C322(0.78)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C322(0.84)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C322(0.80)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C322(0.92)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C322(0.75); C327(0.75)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C322(0.94)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C322(0.99)  LDD0698  [1]
 LDCM0387  CL117 HCT 116 C322(0.92)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C322(1.06)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C322(1.13)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C322(0.88); C327(0.88)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C322(0.96)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C322(1.38); C327(1.54)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C327(0.87); C322(0.93)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C322(1.02); C327(1.06)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C327(0.85); C322(0.89)  LDD0712  [1]
 LDCM0396  CL125 HCT 116 C322(1.37); C327(1.43)  LDD0713  [1]
 LDCM0397  CL126 HCT 116 C327(1.08); C322(1.12)  LDD0714  [1]
 LDCM0398  CL127 HCT 116 C327(0.89); C322(1.08)  LDD0715  [1]
 LDCM0399  CL128 HCT 116 C327(0.81); C322(0.91)  LDD0716  [1]
 LDCM0400  CL13 HCT 116 C322(0.59); C327(0.59)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C322(1.06); C327(1.06)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C322(0.74); C327(0.74)  LDD0719  [1]
 LDCM0407  CL2 HCT 116 C322(0.95); C327(0.95)  LDD0724  [1]
 LDCM0418  CL3 HCT 116 C322(0.97); C327(0.97)  LDD0735  [1]
 LDCM0420  CL31 HCT 116 C322(0.76); C327(0.76)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C322(0.56); C327(0.56)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C322(0.82); C327(0.82)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C322(0.65); C327(0.65)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C322(0.62); C327(0.62)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C322(0.89); C327(0.89)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C322(0.65); C327(0.65)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C322(0.75); C327(0.75)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C322(0.93); C327(0.93)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C322(0.66); C327(0.66)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C322(1.01); C327(1.01)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C322(0.69); C327(0.69)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C322(0.64); C327(0.64)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C322(0.62); C327(0.62)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C322(0.53); C327(0.53)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C322(1.09)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C322(0.90)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C322(1.11)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C322(1.01)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C322(0.86); C327(0.86)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C322(1.07)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C322(1.14)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C322(1.09)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C322(0.62)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C322(0.86)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C322(0.91)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C322(0.74)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C322(0.80)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C322(1.00)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C322(1.01)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C322(0.84); C327(0.84)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C322(1.09)  LDD0769  [1]
 LDCM0462  CL7 HCT 116 C322(0.80); C327(0.80)  LDD0779  [1]
 LDCM0469  CL76 HCT 116 C322(0.74); C327(0.74)  LDD0786  [1]
 LDCM0470  CL77 HCT 116 C322(0.88); C327(0.88)  LDD0787  [1]
 LDCM0471  CL78 HCT 116 C322(0.80); C327(0.80)  LDD0788  [1]
 LDCM0472  CL79 HCT 116 C322(0.72); C327(0.72)  LDD0789  [1]
 LDCM0473  CL8 HCT 116 C322(0.71); C327(0.71)  LDD0790  [1]
 LDCM0474  CL80 HCT 116 C322(0.65); C327(0.65)  LDD0791  [1]
 LDCM0475  CL81 HCT 116 C322(0.66); C327(0.66)  LDD0792  [1]
 LDCM0476  CL82 HCT 116 C322(0.60); C327(0.60)  LDD0793  [1]
 LDCM0477  CL83 HCT 116 C322(0.63); C327(0.63)  LDD0794  [1]
 LDCM0478  CL84 HCT 116 C322(0.71); C327(0.71)  LDD0795  [1]
 LDCM0479  CL85 HCT 116 C322(0.69); C327(0.69)  LDD0796  [1]
 LDCM0480  CL86 HCT 116 C322(0.76); C327(0.76)  LDD0797  [1]
 LDCM0481  CL87 HCT 116 C322(0.83); C327(0.83)  LDD0798  [1]
 LDCM0482  CL88 HCT 116 C322(0.73); C327(0.73)  LDD0799  [1]
 LDCM0483  CL89 HCT 116 C322(0.67); C327(0.67)  LDD0800  [1]
 LDCM0484  CL9 HCT 116 C322(0.98); C327(0.98)  LDD0801  [1]
 LDCM0485  CL90 HCT 116 C322(1.09); C327(1.09)  LDD0802  [1]
 LDCM0486  CL91 PaTu 8988t C327(0.26); C322(0.26)  LDD1365  [1]
 LDCM0487  CL92 PaTu 8988t C327(0.35); C322(0.35)  LDD1366  [1]
 LDCM0488  CL93 PaTu 8988t C327(0.30); C322(0.30)  LDD1367  [1]
 LDCM0489  CL94 PaTu 8988t C327(0.26); C322(0.26)  LDD1368  [1]
 LDCM0490  CL95 PaTu 8988t C327(0.28); C322(0.28)  LDD1369  [1]
 LDCM0491  CL96 PaTu 8988t C327(0.39); C322(0.39)  LDD1370  [1]
 LDCM0492  CL97 PaTu 8988t C327(0.33); C322(0.33)  LDD1371  [1]
 LDCM0493  CL98 PaTu 8988t C327(0.24); C322(0.24)  LDD1372  [1]
 LDCM0494  CL99 PaTu 8988t C327(0.30); C322(0.30)  LDD1373  [1]
 LDCM0427  Fragment51 HCT 116 C322(0.84); C327(0.84)  LDD0744  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclin-dependent kinase 2 (CDK2) CMGC Ser/Thr protein kinase family P24941
Breast cancer type 1 susceptibility protein (BRCA1) . P38398
E3 ubiquitin-protein ligase UHRF2 (UHRF2) . Q96PU4
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Forkhead box protein M1 (FOXM1) . Q08050
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclin-dependent kinase inhibitor 1 (CDKN1A) CDI family P38936
Cyclin-dependent kinase inhibitor 1B (CDKN1B) CDI family P46527
Geminin coiled-coil domain-containing protein 1 (GMNC) GEMC1 family A6NCL1

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 24 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
(2'z,3'e)-5-chloro-5'-chloro-indirubin-3'-oxime Small molecular drug D01PSU
(2'z,3'e)-5-chloro-5'-fluoro-indirubin-3'-oxime Small molecular drug D0B1LM
(2'z,3'e)-5-chloro-5'-hydroxy-indirubin-3'-oxime Small molecular drug D0JR0G
(2'z,3'e)-5-chloro-5'-methyl-indirubin-3'-oxime Small molecular drug D03KLM
(2'z,3'e)-5-fluoro-5'-chloro-indirubin-3'-oxime Small molecular drug D06XIW
(2'z,3'e)-5-fluoro-5'-fluoro-indirubin-3'-oxime Small molecular drug D06GLV
(2'z,3'e)-5-fluoro-5'-hydroxy-indirubin-3'-oxime Small molecular drug D0J3RS
(2'z,3'e)-5-fluoro-5'-methoxy-indirubin-3'-oxime Small molecular drug D04AGE
(2'z,3'e)-5-fluoro-5'-methyl-indirubin-3'-oxime Small molecular drug D0W2FM
(2'z,3'e)-5-nitro-5'-chloro-indirubin-3'-oxime Small molecular drug D0I6AE
(2'z,3'e)-5-nitro-5'-fluoro-indirubin-3'-oxime Small molecular drug D0L5PI
(2'z,3'e)-5-nitro-5'-hydroxy-indirubin-3'-oxime Small molecular drug D0YZ9Y
(2'z,3'e)-5-nitro-5'-methoxy-indirubin-3'-oxime Small molecular drug D0M4XD
(2'z,3'e)-5-nitro-5'-methyl-indirubin-3'-oxime Small molecular drug D0H0EN
2-((3,5-diamino-1h-pyrazol-4-yl)Diazenyl)Phenol Small molecular drug D0F3OM
3,4-di-(4-methoxyphenyl)-1h-pyrrole-2,5-dione Small molecular drug D00NYT
3,4-diphenyl-1h-pyrrole-2,5-dione Small molecular drug D0C3WY
3-((3,5-diamino-1h-pyrazol-4-yl)Diazenyl)Phenol Small molecular drug D0W0BL
3-(4-methoxyphenyl)-4-phenyl-1h-pyrrole-2,5-dione Small molecular drug D0EK0G
3-(Indole-3-yl)-4-phenyl-1h-pyrrole-2,5-dione Small molecular drug D06AOY
4-[(3,5-diamino-1h-pyrazol-4-yl)Diazenyl]Phenol Small molecular drug D0A5RM
5-nitroindirubin-3'-oxime Small molecular drug D0GP3R
Aloisine A Small molecular drug D02XHC
Bms-536924 Small molecular drug D0M4SY
Discontinued
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Pd-0183812 Small molecular drug D0Z0KD

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.