Details of the Target

General Information of Target

Target ID LDTP01452
Target Name Leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2)
Gene Name LRIG2
Gene ID 9860
Synonyms
KIAA0806; LIG2; Leucine-rich repeats and immunoglobulin-like domains protein 2; LIG-2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPAPLGVPEEQLLGCRSRVLSRLLFIAQTALLLLPAAGAGLCPAPCSCRIPLLDCSRRK
LPAPSWRALSGLLPPDTAILDFSHNRLSNWNISLESQTLQEVKMNYNELTEIPYFGEPTS
NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRIT
TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS
LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE
RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN
LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNN
AIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQ
SILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEIL
YDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNE
MPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVF
FIANVKIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAG
GSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIY
LNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSI
TNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYIHKGTDGGTGTRV
ICSDCYDNANIYSRTREYCPYTYIAEEDVLDQTLSSLMVQMPKETYLVHPPQDTTALESL
IPSANREPSAFPTNHERISEKKLPSTQMSGETLQRPVWNINRELGLPHPPFSQQPVHESP
QLHQNEGLAGREPDCSASSMSCHRLQDHAFDFSRTRNIQDGSEGT
Target Bioclass
Immunoglobulin
Subcellular location
Cell membrane
Uniprot ID
O94898
Ensemble ID
ENST00000361127.6
HGNC ID
HGNC:20889

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C919(4.05)  LDD0168  [1]
DBIA
 Probe Info  		C902(1.01); C905(1.01)  LDD0078  [2]
IA-alkyne
 Probe Info  		C623(0.00); C492(0.00); C56(0.00)  LDD0165  [3]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [4]
AOyne
 Probe Info  		15.00  LDD0443  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C919(4.05)  LDD0168  [1]
 LDCM0214  AC1 HEK-293T C310(1.11); C902(1.70); C905(1.70)  LDD0812  [2]
 LDCM0215  AC10 HEK-293T C310(0.93); C902(1.15); C905(1.15)  LDD0813  [2]
 LDCM0216  AC100 HEK-293T C902(0.91); C905(0.91)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C902(0.90); C905(0.90)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C902(0.82); C905(0.82)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C902(1.04); C905(1.04)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C902(1.01); C905(1.01)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C902(0.93); C905(0.93)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C902(0.79); C905(0.79)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C902(0.77); C905(0.77)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C902(0.84); C905(0.84)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C902(0.89); C905(0.89)  LDD0823  [2]
 LDCM0226  AC11 HEK-293T C310(0.78); C902(1.15); C905(1.15)  LDD0824  [2]
 LDCM0227  AC110 HEK-293T C902(0.80); C905(0.80)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C902(0.83); C905(0.83)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C902(0.81); C905(0.81)  LDD0827  [2]
 LDCM0230  AC113 HEK-293T C902(0.87); C905(0.87)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C902(0.61); C905(0.61)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C902(0.53); C905(0.53)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C902(0.84); C905(0.84)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C902(1.08); C905(1.08)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C902(1.09); C905(1.09)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C902(1.05); C905(1.05)  LDD0834  [2]
 LDCM0237  AC12 HEK-293T C310(1.17); C902(1.21); C905(1.21)  LDD0835  [2]
 LDCM0238  AC120 HEK-293T C902(1.15); C905(1.15)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C902(0.96); C905(0.96)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C902(0.89); C905(0.89)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C902(0.98); C905(0.98)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C902(1.41); C905(1.41)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C902(0.95); C905(0.95)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C902(0.91); C905(0.91)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C902(1.25); C905(1.25)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C902(1.10); C905(1.10)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C902(1.21); C905(1.21)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C902(1.10); C905(1.10)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C902(0.94); C905(0.94)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C902(0.96); C905(0.96)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C902(0.96); C905(0.96)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C902(1.23); C905(1.23)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C902(0.79); C905(0.79)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C902(0.98); C905(0.98)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C902(0.81); C905(0.81)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C902(0.96); C905(0.96)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C902(1.19); C905(1.19)  LDD0856  [2]
 LDCM0259  AC14 HEK-293T C310(1.08); C902(1.40); C905(1.40)  LDD0857  [2]
 LDCM0260  AC140 HEK-293T C902(0.80); C905(0.80)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C902(0.86); C905(0.86)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C902(0.77); C905(0.77)  LDD0860  [2]
 LDCM0263  AC143 HCT 116 C902(0.86); C905(0.86)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C902(0.85); C905(0.85)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C902(0.78); C905(0.78)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C902(0.79); C905(0.79)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C902(0.89); C905(0.89)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C902(0.86); C905(0.86)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C902(0.93); C905(0.93)  LDD0586  [2]
 LDCM0270  AC15 HEK-293T C310(1.33); C902(1.37); C905(1.37)  LDD0868  [2]
 LDCM0271  AC150 HCT 116 C902(0.97); C905(0.97)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C902(0.77); C905(0.77)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C902(0.79); C905(0.79)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C902(0.83); C905(0.83)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C902(0.76); C905(0.76)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C902(0.89); C905(0.89)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C902(0.98); C905(0.98)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C902(0.91); C905(0.91)  LDD2161  [2]
 LDCM0276  AC17 HEK-293T C310(0.89)  LDD0874  [2]
 LDCM0277  AC18 HEK-293T C310(0.98)  LDD0875  [2]
 LDCM0278  AC19 HEK-293T C310(0.93)  LDD0876  [2]
 LDCM0279  AC2 HEK-293T C310(1.16); C902(1.51); C905(1.51)  LDD0877  [2]
 LDCM0280  AC20 HEK-293T C310(0.83)  LDD0878  [2]
 LDCM0281  AC21 HEK-293T C310(0.96)  LDD0879  [2]
 LDCM0282  AC22 HEK-293T C310(0.99)  LDD0880  [2]
 LDCM0283  AC23 HEK-293T C310(0.96)  LDD0881  [2]
 LDCM0284  AC24 HEK-293T C310(0.94)  LDD0882  [2]
 LDCM0285  AC25 HEK-293T C310(1.21); C902(0.59); C905(0.59)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C310(1.78); C902(0.67); C905(0.67)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C310(1.88); C902(0.70); C905(0.70)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C310(2.38); C902(0.67); C905(0.67)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C310(2.07); C902(0.73); C905(0.73)  LDD0887  [2]
 LDCM0290  AC3 HEK-293T C310(0.90); C902(1.06); C905(1.06)  LDD0888  [2]
 LDCM0291  AC30 HEK-293T C310(1.97); C902(0.71); C905(0.71)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C310(2.14); C902(0.91); C905(0.91)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C310(2.06); C902(0.55); C905(0.55)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C310(2.44); C902(0.73); C905(0.73)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C310(2.97); C902(0.89); C905(0.89)  LDD0893  [2]
 LDCM0296  AC35 HEK-293T C310(0.71); C902(1.01); C905(1.01)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C310(0.96); C902(1.31); C905(1.31)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C310(0.80); C902(1.06); C905(1.06)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C310(1.16); C902(1.03); C905(1.03)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C310(1.08); C902(1.06); C905(1.06)  LDD0898  [2]
 LDCM0301  AC4 HEK-293T C310(1.09); C902(1.15); C905(1.15)  LDD0899  [2]
 LDCM0302  AC40 HEK-293T C310(0.95); C902(1.31); C905(1.31)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C310(1.04); C902(0.97); C905(0.97)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C310(1.20); C902(1.06); C905(1.06)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C310(1.14); C902(1.10); C905(1.10)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C310(1.11); C902(1.03); C905(1.03)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C310(1.01); C902(0.95); C905(0.95)  LDD0905  [2]
 LDCM0308  AC46 HEK-293T C902(0.94); C905(0.94)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C902(0.92); C905(0.92)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C902(0.90); C905(0.90)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C902(1.05); C905(1.05)  LDD0909  [2]
 LDCM0312  AC5 HEK-293T C310(1.72); C902(1.10); C905(1.10)  LDD0910  [2]
 LDCM0313  AC50 HEK-293T C902(1.10); C905(1.10)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C902(1.05); C905(1.05)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C902(1.14); C905(1.14)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C902(1.17); C905(1.17)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C902(1.00); C905(1.00)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C902(1.10); C905(1.10)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C902(0.94); C905(0.94)  LDD0917  [2]
 LDCM0320  AC57 HEK-293T C310(1.08); C902(0.90); C905(0.90)  LDD0918  [2]
 LDCM0321  AC58 HEK-293T C310(1.50); C902(0.83); C905(0.83)  LDD0919  [2]
 LDCM0322  AC59 HEK-293T C310(1.28); C902(0.74); C905(0.74)  LDD0920  [2]
 LDCM0323  AC6 HEK-293T C310(1.21); C902(1.00); C905(1.00)  LDD0921  [2]
 LDCM0324  AC60 HEK-293T C310(0.72); C902(0.63); C905(0.63)  LDD0922  [2]
 LDCM0325  AC61 HEK-293T C310(1.60); C902(0.62); C905(0.62)  LDD0923  [2]
 LDCM0326  AC62 HEK-293T C310(1.24); C902(0.60); C905(0.60)  LDD0924  [2]
 LDCM0327  AC63 HEK-293T C310(1.63); C902(0.63); C905(0.63)  LDD0925  [2]
 LDCM0328  AC64 HEK-293T C310(1.68); C902(0.70); C905(0.70)  LDD0926  [2]
 LDCM0329  AC65 HEK-293T C310(1.54); C902(0.72); C905(0.72)  LDD0927  [2]
 LDCM0330  AC66 HEK-293T C310(1.72); C902(0.61); C905(0.61)  LDD0928  [2]
 LDCM0331  AC67 HEK-293T C310(1.91); C902(0.76); C905(0.76)  LDD0929  [2]
 LDCM0332  AC68 HCT 116 C902(1.08); C905(1.08)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C902(0.86); C905(0.86)  LDD0650  [2]
 LDCM0334  AC7 HEK-293T C310(1.45); C902(0.90); C905(0.90)  LDD0932  [2]
 LDCM0335  AC70 HCT 116 C902(0.77); C905(0.77)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C902(0.79); C905(0.79)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C902(1.05); C905(1.05)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C902(1.05); C905(1.05)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C902(1.01); C905(1.01)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C902(1.06); C905(1.06)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C902(1.25); C905(1.25)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C902(1.07); C905(1.07)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C902(0.78); C905(0.78)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C902(1.09); C905(1.09)  LDD0661  [2]
 LDCM0345  AC8 HEK-293T C310(1.58); C902(0.91); C905(0.91)  LDD0943  [2]
 LDCM0346  AC80 HCT 116 C902(0.86); C905(0.86)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C902(0.67); C905(0.67)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C902(0.88); C905(0.88)  LDD0665  [2]
 LDCM0349  AC83 HEK-293T C310(0.90); C902(1.26); C905(1.26)  LDD0947  [2]
 LDCM0350  AC84 HEK-293T C310(1.19); C902(1.12); C905(1.12)  LDD0948  [2]
 LDCM0351  AC85 HEK-293T C310(1.18); C902(1.32); C905(1.32)  LDD0949  [2]
 LDCM0352  AC86 HEK-293T C310(1.28); C902(1.31); C905(1.31)  LDD0950  [2]
 LDCM0353  AC87 HEK-293T C310(1.56); C902(1.04); C905(1.04)  LDD0951  [2]
 LDCM0354  AC88 HEK-293T C310(1.38); C902(1.35); C905(1.35)  LDD0952  [2]
 LDCM0355  AC89 HEK-293T C310(1.26); C902(1.31); C905(1.31)  LDD0953  [2]
 LDCM0357  AC90 HEK-293T C310(1.39); C902(1.34); C905(1.34)  LDD0955  [2]
 LDCM0358  AC91 HEK-293T C310(1.18); C902(1.36); C905(1.36)  LDD0956  [2]
 LDCM0359  AC92 HEK-293T C310(1.12); C902(1.05); C905(1.05)  LDD0957  [2]
 LDCM0360  AC93 HEK-293T C310(1.27); C902(1.11); C905(1.11)  LDD0958  [2]
 LDCM0361  AC94 HEK-293T C310(1.73); C902(1.23); C905(1.23)  LDD0959  [2]
 LDCM0362  AC95 HEK-293T C310(1.36); C902(1.11); C905(1.11)  LDD0960  [2]
 LDCM0363  AC96 HEK-293T C310(1.08); C902(1.39); C905(1.39)  LDD0961  [2]
 LDCM0364  AC97 HEK-293T C310(2.21); C902(1.14); C905(1.14)  LDD0962  [2]
 LDCM0365  AC98 HEK-293T C902(0.85); C905(0.85)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C902(0.90); C905(0.90)  LDD0964  [2]
 LDCM0248  AKOS034007472 HEK-293T C310(1.21); C902(1.40); C905(1.40)  LDD0846  [2]
 LDCM0356  AKOS034007680 HEK-293T C310(1.41); C902(1.27); C905(1.27)  LDD0954  [2]
 LDCM0275  AKOS034007705 HEK-293T C310(2.00); C902(1.47); C905(1.47)  LDD0873  [2]
 LDCM0020  ARS-1620 HCC44 C902(1.01); C905(1.01)  LDD0078  [2]
 LDCM0367  CL1 HEK-293T C902(1.29); C905(1.29)  LDD0965  [2]
 LDCM0368  CL10 HEK-293T C902(1.25); C905(1.25)  LDD0966  [2]
 LDCM0369  CL100 HEK-293T C310(1.33); C902(0.99); C905(0.99)  LDD0967  [2]
 LDCM0370  CL101 HEK-293T C310(1.64); C902(1.05); C905(1.05)  LDD0968  [2]
 LDCM0371  CL102 HEK-293T C310(1.24); C902(1.46); C905(1.46)  LDD0969  [2]
 LDCM0372  CL103 HEK-293T C310(1.48); C902(0.86); C905(0.86)  LDD0970  [2]
 LDCM0373  CL104 HEK-293T C310(1.34); C902(0.86); C905(0.86)  LDD0971  [2]
 LDCM0374  CL105 HEK-293T C310(0.91)  LDD0972  [2]
 LDCM0375  CL106 HEK-293T C310(1.06)  LDD0973  [2]
 LDCM0376  CL107 HEK-293T C310(1.07)  LDD0974  [2]
 LDCM0377  CL108 HEK-293T C310(1.00)  LDD0975  [2]
 LDCM0378  CL109 HEK-293T C310(0.96)  LDD0976  [2]
 LDCM0379  CL11 HEK-293T C902(0.89); C905(0.89)  LDD0977  [2]
 LDCM0380  CL110 HEK-293T C310(0.88)  LDD0978  [2]
 LDCM0381  CL111 HEK-293T C310(0.93)  LDD0979  [2]
 LDCM0382  CL112 HEK-293T C310(1.87); C902(0.73); C905(0.73)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C310(2.14); C902(0.71); C905(0.71)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C310(2.91); C902(0.69); C905(0.69)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C310(2.26); C902(0.72); C905(0.72)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C310(2.56); C902(0.74); C905(0.74)  LDD0984  [2]
 LDCM0387  CL117 HEK-293T C310(0.78); C902(1.12); C905(1.12)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C310(0.93); C902(0.79); C905(0.79)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C310(1.05); C902(0.93); C905(0.93)  LDD0987  [2]
 LDCM0390  CL12 HEK-293T C902(0.97); C905(0.97)  LDD0988  [2]
 LDCM0391  CL120 HEK-293T C310(1.10); C902(0.91); C905(0.91)  LDD0989  [2]
 LDCM0392  CL121 HEK-293T C902(1.12); C905(1.12)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C902(1.07); C905(1.07)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C902(1.66); C905(1.66)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C902(1.30); C905(1.30)  LDD0993  [2]
 LDCM0396  CL125 HEK-293T C310(1.12); C902(0.96); C905(0.96)  LDD0994  [2]
 LDCM0397  CL126 HEK-293T C310(0.94); C902(0.97); C905(0.97)  LDD0995  [2]
 LDCM0398  CL127 HEK-293T C310(0.95); C902(0.86); C905(0.86)  LDD0996  [2]
 LDCM0399  CL128 HEK-293T C310(0.92); C902(1.14); C905(1.14)  LDD0997  [2]
 LDCM0400  CL13 HEK-293T C902(0.91); C905(0.91)  LDD0998  [2]
 LDCM0401  CL14 HEK-293T C902(1.36); C905(1.36)  LDD0999  [2]
 LDCM0402  CL15 HEK-293T C902(1.22); C905(1.22)  LDD1000  [2]
 LDCM0403  CL16 HEK-293T C310(1.06); C56(1.02); C492(1.05); C186(1.07)  LDD1607  [6]
 LDCM0404  CL17 HEK-293T C310(1.02); C56(1.05); C492(1.17)  LDD1608  [6]
 LDCM0405  CL18 HEK-293T C310(1.15); C56(1.07); C492(0.98); C919(1.11)  LDD1609  [6]
 LDCM0406  CL19 HEK-293T C310(1.32); C56(1.07); C492(1.03)  LDD1610  [6]
 LDCM0407  CL2 HEK-293T C902(1.04); C905(1.04)  LDD1005  [2]
 LDCM0408  CL20 HEK-293T C310(1.18); C56(1.09); C492(1.25); C919(1.00)  LDD1612  [6]
 LDCM0409  CL21 HEK-293T C310(1.08); C56(1.14); C492(0.99); C919(1.05)  LDD1613  [6]
 LDCM0410  CL22 HEK-293T C310(1.29); C56(0.93); C492(1.43); C919(0.95)  LDD1614  [6]
 LDCM0411  CL23 HEK-293T C310(1.18); C56(1.05); C492(1.27); C919(0.99)  LDD1615  [6]
 LDCM0412  CL24 HEK-293T C310(1.06); C56(1.02); C492(1.16); C919(1.31)  LDD1616  [6]
 LDCM0413  CL25 HEK-293T C310(0.72); C56(0.98); C492(1.19); C919(0.70)  LDD1617  [6]
 LDCM0414  CL26 HEK-293T C310(1.01); C56(0.94); C492(0.93); C902(0.93)  LDD1618  [6]
 LDCM0415  CL27 HEK-293T C310(1.04); C56(1.02); C492(0.98); C623(1.01)  LDD1619  [6]
 LDCM0416  CL28 HEK-293T C310(1.04); C56(1.06); C492(1.04); C186(1.15)  LDD1620  [6]
 LDCM0417  CL29 HEK-293T C310(1.10); C56(1.11); C492(1.84)  LDD1621  [6]
 LDCM0418  CL3 HEK-293T C902(1.07); C905(1.07)  LDD1016  [2]
 LDCM0419  CL30 HEK-293T C310(1.11); C56(0.98); C492(1.00); C919(0.84)  LDD1623  [6]
 LDCM0420  CL31 HEK-293T C902(1.39); C905(1.39)  LDD1018  [2]
 LDCM0421  CL32 HEK-293T C902(1.11); C905(1.11)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C902(1.62); C905(1.62)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C902(1.30); C905(1.30)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C902(1.12); C905(1.12)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C902(1.21); C905(1.21)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C902(1.43); C905(1.43)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C902(1.54); C905(1.54)  LDD1026  [2]
 LDCM0429  CL4 HEK-293T C902(1.05); C905(1.05)  LDD1027  [2]
 LDCM0430  CL40 HEK-293T C902(1.23); C905(1.23)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C902(1.37); C905(1.37)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C902(1.24); C905(1.24)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C902(1.15); C905(1.15)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C902(1.58); C905(1.58)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C902(1.20); C905(1.20)  LDD1033  [2]
 LDCM0436  CL46 HCT 116 C902(1.02); C905(1.02)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C902(1.02); C905(1.02)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C902(1.41); C905(1.41)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C902(1.09); C905(1.09)  LDD0756  [2]
 LDCM0440  CL5 HEK-293T C902(1.12); C905(1.12)  LDD1038  [2]
 LDCM0441  CL50 HCT 116 C902(0.91); C905(0.91)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C902(1.23); C905(1.23)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C902(0.86); C905(0.86)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C902(1.27); C905(1.27)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C902(0.77); C905(0.77)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C902(1.04); C905(1.04)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C902(0.70); C905(0.70)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C902(0.91); C905(0.91)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C902(0.53); C905(0.53)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C902(0.76); C905(0.76)  LDD0767  [2]
 LDCM0451  CL6 HEK-293T C902(1.00); C905(1.00)  LDD1049  [2]
 LDCM0452  CL60 HCT 116 C902(1.27); C905(1.27)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C902(1.93); C905(1.93)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C902(1.44); C905(1.44)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C902(1.46); C905(1.46)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C902(1.05); C905(1.05)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C902(1.17); C905(1.17)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C902(1.59); C905(1.59)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C902(1.38); C905(1.38)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C902(0.85); C905(0.85)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C902(1.73); C905(1.73)  LDD0778  [2]
 LDCM0462  CL7 HEK-293T C902(1.01); C905(1.01)  LDD1060  [2]
 LDCM0463  CL70 HCT 116 C902(1.60); C905(1.60)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C902(1.31); C905(1.31)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C902(1.39); C905(1.39)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C902(1.32); C905(1.32)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C902(2.43); C905(2.43)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C902(0.63); C905(0.63)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C902(0.67); C905(0.67)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C902(0.69); C905(0.69)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C902(0.80); C905(0.80)  LDD0789  [2]
 LDCM0473  CL8 HEK-293T C902(1.15); C905(1.26)  LDD1071  [2]
 LDCM0474  CL80 HCT 116 C902(0.68); C905(0.68)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C902(0.67); C905(0.67)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C902(0.70); C905(0.70)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C902(0.79); C905(0.79)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C902(0.68); C905(0.68)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C902(0.64); C905(0.64)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C902(0.64); C905(0.64)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C902(0.70); C905(0.70)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C902(0.76); C905(0.76)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C902(0.74); C905(0.74)  LDD0800  [2]
 LDCM0484  CL9 HEK-293T C902(1.10); C905(1.15)  LDD1082  [2]
 LDCM0485  CL90 HCT 116 C902(0.76); C905(0.76)  LDD0802  [2]
 LDCM0486  CL91 HEK-293T C310(1.40); C902(0.90); C905(0.90)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C310(0.99); C902(1.76); C905(1.76)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C310(1.28); C902(1.17); C905(1.17)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C310(1.70); C902(1.25); C905(1.25)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C310(1.70); C902(0.92); C905(0.92)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C310(1.86); C902(0.75); C905(0.75)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C310(1.51); C902(0.82); C905(0.82)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C310(0.95); C902(1.55); C905(1.55)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C310(1.01); C902(1.21); C905(1.21)  LDD1092  [2]
 LDCM0495  E2913 HEK-293T C310(1.07); C56(1.12); C492(0.91); C623(0.91)  LDD1698  [6]
 LDCM0468  Fragment33 HCT 116 C902(2.08); C905(2.08)  LDD0785  [2]
 LDCM0427  Fragment51 HEK-293T C902(1.20); C905(1.20)  LDD1025  [2]
 LDCM0022  KB02 HEK-293T C623(1.00); C310(1.00); C492(0.92); C56(1.09)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C623(0.92); C310(0.97); C492(0.99); C56(0.98)  LDD1497  [6]
 LDCM0024  KB05 HEK-293T C623(0.99); C310(0.97); C492(0.88); C56(1.13)  LDD1502  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Platelet-derived growth factor receptor beta (PDGFRB) Tyr protein kinase family P09619
Epidermal growth factor receptor (EGFR) Tyr protein kinase family P00533

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
5 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402