General Information of Experiment

Probe Name Alkylaryl probe 3  Probe Info 
Probe concentration 1 mM
Criteria Quantification: Probe vs DMSO
Quantitative Method
SILAC
In Vivo Experiment Model Model Type Living cell
Derived Tissue Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 23 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00968  Acyl-CoA (8-3)-desaturase (FADS1) 20.0
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 20.0
 LDTP03109  Amine oxidase [flavin-containing] A (MAOA) 20.0
 LDTP03384  Amine oxidase [flavin-containing] B (MAOB) 20.0
 LDTP03540  Heme oxygenase 2 (HMOX2) 20.0
 LDTP04581  Holocytochrome c-type synthase (HCCS) 20.0
 LDTP00957  Lysine-specific histone demethylase 1A (KDM1A) 18.1
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 18.0
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 17.8
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 16.2
 LDTP10215  Carboxymethylenebutenolidase homolog (CMBL) 14.9
 LDTP02074  Aldehyde dehydrogenase, mitochondrial (ALDH2) 14.6
 LDTP00624  Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) 13.6
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 13.0
 LDTP13147  Cathepsin Z (CTSZ) 12.5
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 11.8
 LDTP04232  4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) 10.8
 LDTP10887  Synaptic vesicle membrane protein VAT-1 homolog (VAT1) 7.5
 LDTP10878  Parkinson disease protein 7 (PARK7) 6.3
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 6.3
 LDTP03329  Cathepsin S (CTSS) 5.9
 LDTP02074  Aldehyde dehydrogenase, mitochondrial (ALDH2) 5.6
 LDTP01974  Ferritin heavy chain (FTH1) 5.3
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP16938  Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial (GATD3) 7.2
 LDTP06444  Microtubule-associated protein RP/EB family member 1 (MAPRE1) 6.2

References

1 Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes. bioRxiv, 2020-06.