Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | IMP2070 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 20 uM | |||||
| Criteria | Quantification: Probe vs DMSO | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Acute monocytic leukemia [ICD-11:2A60] | |||||
| Model Name | Human acute monocytic leukemia cells (THP-1) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02198 | Cathepsin D (CTSD) | 11.5 | ||||
| LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 4.2 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 3.5 | ||||
| LDTP02188 | Protein disulfide-isomerase (P4HB) | 3.2 | ||||
| LDTP01768 | Glutamate dehydrogenase 1, mitochondrial (GLUD1) | 2.5 | ||||
| LDTP02679 | Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) | 1.8 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP04426 | B-cell receptor-associated protein 31 (BCAP31) | 9.7 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 2.9 | ||||
| LDTP03405 | Calnexin (CANX) | 2.6 | ||||
| LDTP13824 | Voltage-dependent anion-selective channel protein 3 (VDAC3) | 1.9 | ||||
| LDTP14066 | Hypoxia up-regulated protein 1 (HYOU1) | 1.9 | ||||
| LDTP02609 | ADP/ATP translocase 3 (SLC25A6) | 1.6 | ||||
| LDTP05238 | Solute carrier family 25 member 3 (SLC25A3) | 1.5 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02688 | HLA class I histocompatibility antigen, alpha chain E (HLA-E) | 22.2 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP05160 | Nucleobindin-2 (NUCB2) | 3.9 | ||||
| LDTP02077 | Integrin beta-2 (ITGB2) | 2.2 | ||||
| LDTP02053 | Heat shock protein beta-1 (HSPB1) | 1.9 | ||||
| LDTP00991 | Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) | 1.6 | ||||
| LDTP04500 | Heterogeneous nuclear ribonucleoprotein M (HNRNPM) | 1.5 | ||||
| LDTP02734 | Endoplasmin (HSP90B1) | 1.5 | ||||