Details of the Target

General Information of Target

Target ID LDTP15781
Target Name Coiled-coil domain-containing protein 138 (CCDC138)
Gene Name CCDC138
Gene ID 165055
Synonyms
Coiled-coil domain-containing protein 138
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKPVKHLLTTSNKSANVPALTTKKGLHNLPLSPELKEKHNAKLIHDKIEPMVLRSPPTGE
SILRYALPIPSSKTKNLLPEDEMIGKIIKHLKMVVSTLEETYGHCDQNGEEPFVKHEHEE
LSLSVGDDMNSFLTYCSQFAAQLEEALKEEQNILESLFKWFQWQVNQMEEISKDQTLLQA
EPPKPDKTVILNIAEIVRLVQRFEELKNRLKQRSKSSVKVMLSKTMDKENRPEAVKSCEA
LAQKIEEFLEAHSTDEFKDVSATEPQTAHSMTNRFNAMLKVFENQANMLERAVNDQVLLD
AEYKQMQCDFQLLSEEKLVLENELQKLKDKEKTKPTNNRTKKAVKTVKKKDKGKSEDSEK
KMSPEKEFKIKEDLDQVQKVARLEIENKVLQEQLKQALQEAEKAKHQLNYFLNQEKLLKS
EGKTETTMQVGNSQTKVKGEDSKNIPLEKETRKSLVSDSGGQRTSDKIQEYPQITAQSGR
LIEKSSEKKRSSPAISDLSQILKSQDESAFLESSNEVSVAENQSYKSPSETHDKSLTTVS
SSKEVQDSLSVGTLAQKNETVISPFILPPVLTESKKADVSEEQLQKMTEEQTYQAAEKSQ
ADSEVPDENLMVENKDSVTKVQIEQMKQRTSSMERHEETLTTPQLPEDMVLVSRIQSETK
NLKATRNESFHSHNDVPEENLMLEQDTKSKTEVEVKKQKSFQDNQLSTHNEVPNERLVVE
HQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRI
ITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVSKI
QVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVI
SVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKL
QAKVTSRKIKNEAASELPDTAENLPAMYPSISDLIIQFDLNKVVETDIESLRGALGRRLL
NDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIK
TQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSKSHGETDKEHLADDTGRGIIKGSINAQ
LKGHQKTDKNFFAYATGRGLMKESTTTQLKSHPETDKEFLADAIGRGIIIGPITTQLKSH
RETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRTHYDVN
LFKNKDMSVQRQEGIFTRSITPSKFPTKVINLSPFENKEETYEYSSPYVTAPSKAIYRTY
RAGPSFSKDIHLPLLNQLPSGHSKVVTLSQKTIEFTLPTVTNTVGKPTYKVLHAAARKSV
PHPYF
Target Bioclass
Other
Uniprot ID
Q96M89
Ensemble ID
ENST00000295124.9
HGNC ID
HGNC:26531

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
786O SNV: p.P635S .
C32 SNV: p.I396T .
CAL78 SNV: p.T522I .
HT115 SNV: p.E256K .
IM95 SNV: p.S662G .
Ishikawa (Heraklio) 02 ER Insertion: p.N634KfsTer10 .
LN229 SNV: p.K276E .
LS180 Deletion: p.L212YfsTer15 .
RKO Deletion: p.K284NfsTer3 .
RPMI8226 SNV: p.P665S .
SNU1 Deletion: p.K284NfsTer3 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C28(2.24); C193(2.62)  LDD0168  [1]
DBIA
 Probe Info  		C28(0.98)  LDD0078  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
ENE
 Probe Info  		N.A.  LDD0006  [4]
IPM
 Probe Info  		N.A.  LDD0005  [4]
PPMS
 Probe Info  		N.A.  LDD0008  [4]
VSF
 Probe Info  		N.A.  LDD0007  [4]
YN-1
 Probe Info  		D297(0.00); E291(0.00); E292(0.00)  LDD0446  [5]
AOyne
 Probe Info  		15.00  LDD0443  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C28(2.24); C193(2.62)  LDD0168  [1]
 LDCM0026  4SU-RNA+native RNA HEK-293T C28(2.71); C193(5.24)  LDD0169  [1]
 LDCM0214  AC1 HEK-293T C147(1.01); C148(0.91); C161(1.23)  LDD0812  [2]
 LDCM0215  AC10 HCT 116 C147(0.95); C161(0.95)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C147(1.00); C161(1.00)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C147(1.28); C161(1.28)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C147(1.13); C161(1.13)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C147(1.40); C161(1.40)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C147(1.16); C161(1.16)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C147(1.33); C161(1.33)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C147(1.28); C161(1.28)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C147(1.26); C161(1.12)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C147(1.09); C161(1.09)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C147(1.09); C161(1.12)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C147(1.16); C161(1.16)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C147(1.34); C161(1.48)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C147(1.29); C161(1.48)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C147(1.15); C161(1.25)  LDD0546  [2]
 LDCM0230  AC113 HEK-293T C147(1.30); C148(1.26); C161(1.47)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C147(1.14); C148(1.06); C161(1.12)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C147(1.17); C148(1.08); C161(1.18)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C147(1.20); C148(1.15); C161(1.32)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C147(1.12); C148(1.24); C161(1.21)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C147(1.16); C148(1.19); C161(1.47)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C147(1.05); C148(1.16); C161(1.60)  LDD0834  [2]
 LDCM0237  AC12 HCT 116 C147(0.93); C161(0.93)  LDD0554  [2]
 LDCM0238  AC120 HEK-293T C147(1.13); C148(1.38); C161(1.43)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C147(1.27); C148(1.56); C161(1.64)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C147(1.00); C148(1.20); C161(1.72)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C147(0.94); C148(1.21); C161(1.65)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C147(1.32); C148(1.53); C161(1.61)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C147(1.16); C148(1.52); C161(1.65)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C147(1.18); C148(1.72); C161(2.49)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C147(1.06); C148(1.86); C161(1.69)  LDD0843  [2]
 LDCM0246  AC128 HCT 116 C147(0.31); C161(0.31)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C147(0.31); C161(0.31)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C147(0.32); C161(0.32)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C147(0.34); C161(0.34)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C147(0.37); C161(0.37)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C147(0.33); C161(0.33)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C147(0.45); C161(0.45)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C147(0.42); C161(0.42)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C147(0.37); C161(0.37)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C147(0.42); C161(0.42)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C147(0.45); C161(0.45)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C147(0.42); C161(0.42)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C147(1.02); C161(1.02)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C147(0.52); C161(0.52)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C147(0.53); C161(0.53)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C147(0.37); C161(0.37)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C147(1.11); C161(1.11)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C147(1.22); C161(1.22)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C147(1.11); C161(1.11)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C147(1.29); C161(1.29)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C147(1.35); C161(1.35)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C147(1.71); C161(1.71)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C147(1.54); C161(1.54)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C147(0.85); C161(0.85)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C147(1.17); C161(1.17)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C147(1.01); C161(1.01)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C147(1.32); C161(1.32)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C147(1.69); C161(1.69)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C147(1.25); C161(1.25)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C147(1.18); C161(1.18)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C147(1.11); C161(1.11)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C147(0.97); C161(0.97)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C147(0.67); C161(0.67)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C147(0.90); C161(0.90)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C147(0.70); C161(0.70)  LDD0595  [2]
 LDCM0279  AC2 HEK-293T C147(1.26); C148(1.27); C161(1.30)  LDD0877  [2]
 LDCM0280  AC20 HCT 116 C147(0.91); C161(0.91)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C147(0.75); C161(0.75)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C147(0.76); C161(0.76)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C147(0.60); C161(0.60)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C147(0.64); C161(0.64)  LDD0601  [2]
 LDCM0285  AC25 HEK-293T C147(0.92); C148(1.18); C161(1.23)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C147(0.93); C148(1.00); C161(1.09)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C147(0.94); C148(0.93); C161(1.39)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C147(1.23); C148(0.91); C161(1.38)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C147(0.88); C148(1.67); C161(1.11)  LDD0887  [2]
 LDCM0290  AC3 HEK-293T C147(0.98); C148(0.95); C161(1.01)  LDD0888  [2]
 LDCM0291  AC30 HEK-293T C147(1.05); C148(1.35); C161(1.13)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C147(1.02); C148(1.04); C161(0.95)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C147(1.09); C148(1.23); C161(1.11)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C147(1.02); C148(1.81); C161(1.19)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C147(1.16); C148(1.21); C161(1.19)  LDD0893  [2]
 LDCM0296  AC35 HEK-293T C147(1.08); C148(1.17); C161(0.94)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C147(0.94); C148(1.07); C161(0.94)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C147(1.16); C148(1.06); C161(1.11)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C147(1.23); C148(1.36); C161(1.05)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C147(1.22); C148(1.27); C161(1.11)  LDD0898  [2]
 LDCM0301  AC4 HEK-293T C147(0.96); C148(0.93); C161(1.02)  LDD0899  [2]
 LDCM0302  AC40 HEK-293T C147(1.18); C148(1.17); C161(1.17)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C147(1.09); C148(1.01); C161(1.05)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C147(1.04); C148(1.08); C161(1.00)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C147(1.17); C148(1.29); C161(1.23)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C147(1.12); C148(1.07); C161(1.10)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C147(1.42); C148(1.46); C161(1.16)  LDD0905  [2]
 LDCM0308  AC46 HEK-293T C147(1.12); C148(1.19); C161(0.98)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C147(0.99); C148(1.49); C161(0.92)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C147(0.98); C148(1.05); C161(0.97)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C147(0.93); C148(1.60); C161(1.05)  LDD0909  [2]
 LDCM0312  AC5 HEK-293T C147(1.12); C148(1.06); C161(1.14)  LDD0910  [2]
 LDCM0313  AC50 HEK-293T C147(1.14); C148(1.25); C161(1.03)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C147(1.00); C148(1.30); C161(1.10)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C147(1.21); C148(1.41); C161(1.17)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C147(1.57); C148(1.72); C161(1.23)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C147(1.08); C148(1.81); C161(1.12)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C147(1.24); C148(1.46); C161(1.17)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C147(1.05); C148(1.37); C161(0.92)  LDD0917  [2]
 LDCM0320  AC57 HEK-293T C147(1.64); C161(1.23)  LDD0918  [2]
 LDCM0321  AC58 HEK-293T C147(1.16); C161(1.01)  LDD0919  [2]
 LDCM0322  AC59 HEK-293T C147(0.96); C161(1.03)  LDD0920  [2]
 LDCM0323  AC6 HCT 116 C147(1.08); C161(1.08)  LDD0640  [2]
 LDCM0324  AC60 HEK-293T C147(1.05); C161(1.08)  LDD0922  [2]
 LDCM0325  AC61 HEK-293T C147(0.78); C161(0.76)  LDD0923  [2]
 LDCM0326  AC62 HEK-293T C147(1.10); C161(0.76)  LDD0924  [2]
 LDCM0327  AC63 HEK-293T C147(0.94); C161(1.18)  LDD0925  [2]
 LDCM0328  AC64 HEK-293T C147(1.07); C161(0.88)  LDD0926  [2]
 LDCM0329  AC65 HEK-293T C147(0.95); C161(0.87)  LDD0927  [2]
 LDCM0330  AC66 HEK-293T C147(1.29); C161(1.01)  LDD0928  [2]
 LDCM0331  AC67 HEK-293T C147(0.94); C161(1.01)  LDD0929  [2]
 LDCM0332  AC68 HEK-293T C147(0.80); C148(0.70); C161(0.87); C574(1.06)  LDD0930  [2]
 LDCM0333  AC69 HEK-293T C147(0.78); C148(0.87); C161(0.83); C574(1.04)  LDD0931  [2]
 LDCM0334  AC7 HCT 116 C147(1.02); C161(1.02)  LDD0651  [2]
 LDCM0335  AC70 HEK-293T C147(0.70); C148(1.02); C161(1.06); C574(0.80)  LDD0933  [2]
 LDCM0336  AC71 HEK-293T C147(0.76); C148(1.07); C161(0.99); C574(0.78)  LDD0934  [2]
 LDCM0337  AC72 HEK-293T C147(0.86); C148(0.91); C161(1.01); C574(0.57)  LDD0935  [2]
 LDCM0338  AC73 HEK-293T C147(0.73); C148(0.98); C161(1.16); C574(0.73)  LDD0936  [2]
 LDCM0339  AC74 HEK-293T C147(0.65); C148(0.88); C161(0.88); C574(0.92)  LDD0937  [2]
 LDCM0340  AC75 HEK-293T C147(0.95); C148(0.90); C161(1.05); C574(0.78)  LDD0938  [2]
 LDCM0341  AC76 HEK-293T C147(0.76); C148(0.79); C161(1.03); C574(0.99)  LDD0939  [2]
 LDCM0342  AC77 HEK-293T C147(0.91); C148(1.15); C161(1.21); C574(0.68)  LDD0940  [2]
 LDCM0343  AC78 HEK-293T C147(0.82); C148(1.03); C161(1.16); C574(0.96)  LDD0941  [2]
 LDCM0344  AC79 HEK-293T C147(0.76); C148(1.11); C161(0.95); C574(0.70)  LDD0942  [2]
 LDCM0345  AC8 HCT 116 C147(0.86); C161(0.86)  LDD0662  [2]
 LDCM0346  AC80 HEK-293T C147(0.81); C148(0.89); C161(1.19); C574(0.95)  LDD0944  [2]
 LDCM0347  AC81 HEK-293T C147(0.81); C148(1.19); C161(1.15); C574(0.98)  LDD0945  [2]
 LDCM0348  AC82 HEK-293T C147(0.72); C148(1.30); C161(1.49); C574(0.84)  LDD0946  [2]
 LDCM0349  AC83 HEK-293T C147(1.19); C148(1.25); C161(1.32); C574(0.64)  LDD0947  [2]
 LDCM0350  AC84 HEK-293T C147(1.54); C148(1.45); C161(1.71); C574(0.30)  LDD0948  [2]
 LDCM0351  AC85 HEK-293T C147(1.43); C148(1.23); C161(1.23); C574(0.95)  LDD0949  [2]
 LDCM0352  AC86 HEK-293T C147(1.70); C148(1.26); C161(1.41); C574(0.60)  LDD0950  [2]
 LDCM0353  AC87 HEK-293T C147(1.70); C148(1.26); C161(1.37); C574(0.55)  LDD0951  [2]
 LDCM0354  AC88 HEK-293T C147(1.77); C148(1.51); C161(1.40); C574(0.47)  LDD0952  [2]
 LDCM0355  AC89 HEK-293T C147(1.51); C148(1.63); C161(1.54); C574(0.35)  LDD0953  [2]
 LDCM0357  AC90 HEK-293T C147(1.71); C148(1.54); C161(1.25); C574(0.42)  LDD0955  [2]
 LDCM0358  AC91 HEK-293T C147(1.70); C148(1.43); C161(1.13); C574(0.57)  LDD0956  [2]
 LDCM0359  AC92 HEK-293T C147(2.48); C148(1.15); C161(1.68); C574(0.77)  LDD0957  [2]
 LDCM0360  AC93 HEK-293T C147(1.90); C148(1.15); C161(1.39); C574(0.48)  LDD0958  [2]
 LDCM0361  AC94 HEK-293T C147(1.42); C148(1.11); C161(1.17); C574(0.27)  LDD0959  [2]
 LDCM0362  AC95 HEK-293T C147(1.81); C148(1.35); C161(1.40); C574(0.40)  LDD0960  [2]
 LDCM0363  AC96 HEK-293T C147(2.83); C148(1.34); C161(1.40); C574(0.70)  LDD0961  [2]
 LDCM0364  AC97 HEK-293T C147(0.94); C148(1.93); C161(1.36); C574(0.48)  LDD0962  [2]
 LDCM0365  AC98 HCT 116 C147(1.44); C161(1.44)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C147(1.10); C161(1.10)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C147(0.96); C161(0.96)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C147(1.26); C161(1.26)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C147(1.00); C161(1.00)  LDD0592  [2]
 LDCM0020  ARS-1620 HCC44 C28(0.98)  LDD0078  [2]
 LDCM0367  CL1 HCT 116 C147(1.35); C161(1.35)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C147(0.80); C161(0.80)  LDD0685  [2]
 LDCM0369  CL100 HEK-293T C147(0.95); C148(0.85); C161(1.28)  LDD0967  [2]
 LDCM0370  CL101 HCT 116 C147(0.93); C161(0.93)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C147(1.46); C161(1.46)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C147(0.90); C161(0.90)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C147(0.94); C161(0.94)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C147(0.74); C161(0.74)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C147(0.73); C161(0.73)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C147(0.69); C161(0.69)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C147(0.63); C161(0.63)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C147(0.84); C161(0.84)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C147(1.62); C161(1.62)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C147(0.73); C161(0.73)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C147(0.78); C161(0.78)  LDD0698  [2]
 LDCM0382  CL112 HEK-293T C147(1.05); C148(1.07); C161(1.27)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C147(1.15); C148(0.91); C161(1.24)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C147(0.91); C148(1.48); C161(1.52)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C147(1.05); C148(1.29); C161(1.43)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C147(1.02); C148(1.35); C161(1.26)  LDD0984  [2]
 LDCM0387  CL117 HEK-293T C147(1.28); C148(1.30); C161(1.08)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C147(0.88); C148(0.85); C161(0.84)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C147(1.03); C148(0.94); C161(1.06)  LDD0987  [2]
 LDCM0390  CL12 HCT 116 C147(0.89); C161(0.89)  LDD0707  [2]
 LDCM0391  CL120 HEK-293T C147(1.11); C148(1.12); C161(1.04)  LDD0989  [2]
 LDCM0392  CL121 HEK-293T C147(1.14); C148(1.28); C161(1.30)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C147(1.17); C148(1.29); C161(0.99)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C147(1.88); C148(1.76); C161(1.42)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C147(1.14); C148(1.67); C161(1.09)  LDD0993  [2]
 LDCM0396  CL125 HEK-293T C147(1.07); C161(1.24)  LDD0994  [2]
 LDCM0397  CL126 HEK-293T C147(1.29); C161(1.25)  LDD0995  [2]
 LDCM0398  CL127 HEK-293T C147(1.28); C161(1.11)  LDD0996  [2]
 LDCM0399  CL128 HEK-293T C147(1.28); C161(1.35)  LDD0997  [2]
 LDCM0400  CL13 HCT 116 C147(1.09); C161(1.09)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C147(0.97); C161(0.97)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C147(1.13); C161(1.13)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C147(0.97); C161(0.97)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C147(1.06); C161(1.06)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C147(0.79); C161(0.79)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C147(0.87); C161(0.87)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C147(1.23); C161(1.23)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C147(0.79); C161(0.79)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C147(1.14); C161(1.14)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C147(0.87); C161(0.87)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C147(0.82); C161(0.82)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C147(0.79); C161(0.79)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C147(0.92); C161(0.92)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C147(1.23); C161(1.23)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C147(0.76); C161(0.76)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C147(0.80); C161(0.80)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C147(0.70); C161(0.70)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C147(0.92); C161(0.92)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C147(0.82); C161(0.82)  LDD0736  [2]
 LDCM0420  CL31 HEK-293T C147(1.02); C148(1.01); C161(1.23); C574(1.54)  LDD1018  [2]
 LDCM0421  CL32 HEK-293T C147(1.04); C148(1.16); C161(1.17); C574(0.85)  LDD1019  [2]
 LDCM0422  CL33 HEK-293T C147(4.30); C148(3.37); C161(2.72); C574(0.75)  LDD1020  [2]
 LDCM0423  CL34 HEK-293T C147(1.21); C148(1.14); C161(1.15); C574(0.56)  LDD1021  [2]
 LDCM0424  CL35 HEK-293T C147(1.08); C148(1.20); C161(1.34); C574(0.59)  LDD1022  [2]
 LDCM0425  CL36 HEK-293T C147(1.13); C148(1.19); C161(1.20); C574(0.79)  LDD1023  [2]
 LDCM0426  CL37 HEK-293T C147(1.23); C148(1.21); C161(1.21); C574(1.06)  LDD1024  [2]
 LDCM0428  CL39 HEK-293T C147(1.45); C148(1.46); C161(1.59); C574(0.42)  LDD1026  [2]
 LDCM0429  CL4 HCT 116 C147(0.95); C161(0.95)  LDD0746  [2]
 LDCM0430  CL40 HEK-293T C147(1.13); C148(1.00); C161(1.27); C574(0.83)  LDD1028  [2]
 LDCM0431  CL41 HEK-293T C147(1.64); C148(1.44); C161(1.63); C574(0.41)  LDD1029  [2]
 LDCM0432  CL42 HEK-293T C147(1.08); C148(1.15); C161(1.36); C574(0.36)  LDD1030  [2]
 LDCM0433  CL43 HEK-293T C147(1.13); C148(1.17); C161(1.31); C574(0.41)  LDD1031  [2]
 LDCM0434  CL44 HEK-293T C147(1.18); C148(1.14); C161(1.20); C574(0.88)  LDD1032  [2]
 LDCM0435  CL45 HEK-293T C147(1.30); C148(1.28); C161(1.40); C574(0.40)  LDD1033  [2]
 LDCM0436  CL46 HCT 116 C147(1.21); C161(1.21)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C147(0.75); C161(0.75)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C147(0.87); C161(0.87)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C147(0.79); C161(0.79)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C147(0.97); C161(0.97)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C147(0.79); C161(0.79)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C147(0.85); C161(0.85)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C147(1.02); C161(1.02)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C147(0.91); C161(0.91)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C147(1.04); C161(1.04)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C147(0.80); C161(0.80)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C147(0.73); C161(0.73)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C147(0.94); C161(0.94)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C147(1.13); C161(1.13)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C147(0.74); C161(0.74)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C147(1.04); C161(1.04)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C147(0.78); C161(0.78)  LDD0769  [2]
 LDCM0453  CL61 HEK-293T C147(0.85); C148(1.17); C161(1.02)  LDD1051  [2]
 LDCM0454  CL62 HEK-293T C147(0.87); C148(0.63); C161(1.09)  LDD1052  [2]
 LDCM0455  CL63 HEK-293T C147(0.90); C148(0.90); C161(1.07)  LDD1053  [2]
 LDCM0456  CL64 HEK-293T C147(1.48); C148(0.58); C161(1.43)  LDD1054  [2]
 LDCM0457  CL65 HEK-293T C147(1.00); C148(0.57); C161(1.36)  LDD1055  [2]
 LDCM0458  CL66 HEK-293T C147(1.05); C148(0.67); C161(1.20)  LDD1056  [2]
 LDCM0459  CL67 HEK-293T C147(0.99); C148(0.48); C161(1.12)  LDD1057  [2]
 LDCM0460  CL68 HEK-293T C147(0.85); C148(0.42); C161(1.22)  LDD1058  [2]
 LDCM0461  CL69 HEK-293T C147(1.00); C148(0.33); C161(1.09)  LDD1059  [2]
 LDCM0462  CL7 HCT 116 C147(0.79); C161(0.79)  LDD0779  [2]
 LDCM0463  CL70 HEK-293T C147(0.99); C148(0.45); C161(1.13)  LDD1061  [2]
 LDCM0464  CL71 HEK-293T C147(1.06); C148(0.55); C161(1.35)  LDD1062  [2]
 LDCM0465  CL72 HEK-293T C147(0.94); C148(0.49); C161(1.07)  LDD1063  [2]
 LDCM0466  CL73 HEK-293T C147(1.26); C148(0.44); C161(1.37)  LDD1064  [2]
 LDCM0467  CL74 HEK-293T C147(0.91); C148(0.76); C161(1.46)  LDD1065  [2]
 LDCM0469  CL76 HEK-293T C147(1.23); C148(1.24); C161(1.12)  LDD1067  [2]
 LDCM0470  CL77 HEK-293T C147(1.81); C148(2.46); C161(1.39)  LDD1068  [2]
 LDCM0471  CL78 HEK-293T C147(0.84); C148(0.90); C161(0.81)  LDD1069  [2]
 LDCM0472  CL79 HEK-293T C147(1.04); C148(0.96); C161(1.05)  LDD1070  [2]
 LDCM0473  CL8 HCT 116 C147(3.89); C161(3.89)  LDD0790  [2]
 LDCM0474  CL80 HEK-293T C147(1.00); C148(1.20); C161(0.92)  LDD1072  [2]
 LDCM0475  CL81 HEK-293T C147(0.93); C148(1.06); C161(0.96)  LDD1073  [2]
 LDCM0476  CL82 HEK-293T C147(0.92); C148(1.09); C161(1.00)  LDD1074  [2]
 LDCM0477  CL83 HEK-293T C147(0.86); C148(0.98); C161(1.19)  LDD1075  [2]
 LDCM0478  CL84 HEK-293T C147(1.09); C148(1.20); C161(1.02)  LDD1076  [2]
 LDCM0479  CL85 HEK-293T C147(1.00); C148(1.13); C161(0.86)  LDD1077  [2]
 LDCM0480  CL86 HEK-293T C147(1.07); C148(1.17); C161(0.96)  LDD1078  [2]
 LDCM0481  CL87 HEK-293T C147(1.24); C148(1.16); C161(1.06)  LDD1079  [2]
 LDCM0482  CL88 HEK-293T C147(1.43); C148(1.41); C161(1.25)  LDD1080  [2]
 LDCM0483  CL89 HEK-293T C147(0.96); C148(0.96); C161(0.92)  LDD1081  [2]
 LDCM0484  CL9 HCT 116 C147(1.07); C161(1.07)  LDD0801  [2]
 LDCM0485  CL90 HEK-293T C147(3.45); C148(3.95); C161(2.27)  LDD1083  [2]
 LDCM0486  CL91 HEK-293T C147(1.02); C148(0.85); C161(1.14)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C147(1.22); C148(1.48); C161(1.12)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C147(1.08); C148(1.22); C161(1.10)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C147(1.24); C148(1.36); C161(1.41)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C147(2.55); C148(2.35); C161(2.42)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C147(1.08); C148(1.17); C161(1.14)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C147(1.35); C148(1.51); C161(1.19)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C147(1.10); C148(1.25); C161(1.15)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C147(1.36); C148(1.37); C161(1.20)  LDD1092  [2]
 LDCM0495  E2913 HEK-293T C193(0.84); C583(1.04); C641(1.03); C28(1.15)  LDD1698  [7]
 LDCM0468  Fragment33 HEK-293T C147(1.20); C148(0.57); C161(1.63)  LDD1066  [2]
 LDCM0427  Fragment51 HEK-293T C147(1.15); C148(1.10); C161(1.22); C574(0.83)  LDD1025  [2]
 LDCM0022  KB02 HCT 116 C148(11.24); C161(11.24)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C148(3.02); C161(3.02)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C148(11.35); C161(11.35)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C147(1.26); C148(1.26); C161(1.26)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Serine/threonine-protein kinase N1 (PKN1) AGC Ser/Thr protein kinase family Q16512
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein FAM161B (FAM161B) FAM161 family Q96MY7
Keratin, type I cytoskeletal 27 (KRT27) Intermediate filament family Q7Z3Y8
TRAF3-interacting JNK-activating modulator (TRAF3IP3) . Q9Y228
Ubiquitin-associated domain-containing protein 1 (UBAC1) . Q9BSL1

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
6 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402