Details of the Target

General Information of Target

Target ID LDTP14904
Target Name DNA-directed RNA polymerase I subunit RPA43 (POLR1F)
Gene Name POLR1F
Gene ID 221830
Synonyms
TWISTNB; DNA-directed RNA polymerase I subunit RPA43; DNA-directed RNA polymerase I subunit F; Twist neighbor protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDS
SAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTV
RFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGN
PDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLN
RVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQAENEHIHMDNLAQMPMISIPRV
ESPLEKVTSVQNHITAFAEVT
Target Bioclass
Enzyme
Family
Eukaryotic RPA43 RNA polymerase subunit family
Subcellular location
Nucleus, nucleolus
Function
Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.
Uniprot ID
Q3B726
Ensemble ID
ENST00000222567.6
HGNC ID
HGNC:18027

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
BTD
 Probe Info  		C47(0.95)  LDD2093  [2]
AHL-Pu-1
 Probe Info  		C193(4.40)  LDD0171  [3]
Acrolein
 Probe Info  		N.A.  LDD0221  [4]
DBIA
 Probe Info  		C193(1.26)  LDD0080  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [6]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [6]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [6]
IPM
 Probe Info  		N.A.  LDD0025  [7]
TFBX
 Probe Info  		C47(0.00); C193(0.00)  LDD0148  [7]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [4]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C174
 Probe Info  		5.94  LDD1854  [9]
C266
 Probe Info  		8.51  LDD1937  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C193(10.73)  LDD0371  [3]
 LDCM0026  4SU-RNA+native RNA DM93 C193(4.40)  LDD0171  [3]
 LDCM0214  AC1 HEK-293T C193(1.00)  LDD1507  [10]
 LDCM0215  AC10 HEK-293T C193(1.02)  LDD1508  [10]
 LDCM0237  AC12 HEK-293T C193(1.02); C47(1.02)  LDD1510  [10]
 LDCM0259  AC14 HEK-293T C193(0.93); C47(1.05)  LDD1512  [10]
 LDCM0270  AC15 HEK-293T C193(1.04); C47(1.30); C28(0.76)  LDD1513  [10]
 LDCM0276  AC17 HEK-293T C193(1.03)  LDD1515  [10]
 LDCM0277  AC18 HEK-293T C193(1.14)  LDD1516  [10]
 LDCM0279  AC2 HEK-293T C193(0.96)  LDD1518  [10]
 LDCM0280  AC20 HEK-293T C193(1.04); C47(1.05)  LDD1519  [10]
 LDCM0281  AC21 HEK-293T C193(0.97); C47(1.02)  LDD1520  [10]
 LDCM0282  AC22 HEK-293T C193(0.94); C47(0.93)  LDD1521  [10]
 LDCM0283  AC23 HEK-293T C193(1.06); C47(1.20); C28(0.82)  LDD1522  [10]
 LDCM0284  AC24 HEK-293T C47(0.86)  LDD1523  [10]
 LDCM0285  AC25 HEK-293T C193(1.00)  LDD1524  [10]
 LDCM0286  AC26 HEK-293T C193(0.98)  LDD1525  [10]
 LDCM0288  AC28 HEK-293T C193(0.90); C47(1.14)  LDD1527  [10]
 LDCM0289  AC29 HEK-293T C193(1.06); C47(0.86)  LDD1528  [10]
 LDCM0291  AC30 HEK-293T C193(0.96); C47(0.98)  LDD1530  [10]
 LDCM0292  AC31 HEK-293T C193(0.96); C47(1.07); C28(1.08)  LDD1531  [10]
 LDCM0293  AC32 HEK-293T C47(0.90)  LDD1532  [10]
 LDCM0294  AC33 HEK-293T C193(1.00)  LDD1533  [10]
 LDCM0295  AC34 HEK-293T C193(1.27)  LDD1534  [10]
 LDCM0297  AC36 HEK-293T C193(1.06); C47(1.03)  LDD1536  [10]
 LDCM0298  AC37 HEK-293T C193(1.06); C47(1.00)  LDD1537  [10]
 LDCM0299  AC38 HEK-293T C193(1.02); C47(0.97)  LDD1538  [10]
 LDCM0300  AC39 HEK-293T C193(1.00); C47(1.19); C28(1.11)  LDD1539  [10]
 LDCM0301  AC4 HEK-293T C193(1.04); C47(1.01)  LDD1540  [10]
 LDCM0302  AC40 HEK-293T C47(0.95)  LDD1541  [10]
 LDCM0303  AC41 HEK-293T C193(1.05)  LDD1542  [10]
 LDCM0304  AC42 HEK-293T C193(1.01)  LDD1543  [10]
 LDCM0306  AC44 HEK-293T C193(1.24); C47(1.04)  LDD1545  [10]
 LDCM0307  AC45 HEK-293T C193(1.00); C47(0.95)  LDD1546  [10]
 LDCM0308  AC46 HEK-293T C193(1.02); C47(1.10)  LDD1547  [10]
 LDCM0309  AC47 HEK-293T C193(1.00); C47(1.78); C28(0.81)  LDD1548  [10]
 LDCM0310  AC48 HEK-293T C47(0.77)  LDD1549  [10]
 LDCM0311  AC49 HEK-293T C193(1.03)  LDD1550  [10]
 LDCM0312  AC5 HEK-293T C193(0.93); C47(0.88)  LDD1551  [10]
 LDCM0313  AC50 HEK-293T C193(1.00)  LDD1552  [10]
 LDCM0315  AC52 HEK-293T C193(1.14); C47(1.06)  LDD1554  [10]
 LDCM0316  AC53 HEK-293T C193(0.92); C47(0.94)  LDD1555  [10]
 LDCM0317  AC54 HEK-293T C193(0.88); C47(0.96)  LDD1556  [10]
 LDCM0318  AC55 HEK-293T C193(0.94); C47(1.37); C28(0.98)  LDD1557  [10]
 LDCM0319  AC56 HEK-293T C47(0.95)  LDD1558  [10]
 LDCM0320  AC57 HEK-293T C193(1.04)  LDD1559  [10]
 LDCM0321  AC58 HEK-293T C193(1.13)  LDD1560  [10]
 LDCM0323  AC6 HEK-293T C193(1.02); C47(0.85)  LDD1562  [10]
 LDCM0324  AC60 HEK-293T C193(0.93); C47(1.04)  LDD1563  [10]
 LDCM0325  AC61 HEK-293T C193(0.90); C47(1.02)  LDD1564  [10]
 LDCM0326  AC62 HEK-293T C193(1.02); C47(1.01)  LDD1565  [10]
 LDCM0327  AC63 HEK-293T C193(1.09); C47(1.83); C28(0.75)  LDD1566  [10]
 LDCM0328  AC64 HEK-293T C47(0.81)  LDD1567  [10]
 LDCM0334  AC7 HEK-293T C193(0.95); C47(1.09); C28(1.33)  LDD1568  [10]
 LDCM0345  AC8 HEK-293T C47(1.01)  LDD1569  [10]
 LDCM0248  AKOS034007472 HEK-293T C193(1.04); C47(0.95)  LDD1511  [10]
 LDCM0356  AKOS034007680 HEK-293T C193(0.98)  LDD1570  [10]
 LDCM0275  AKOS034007705 HEK-293T C47(0.85)  LDD1514  [10]
 LDCM0156  Aniline NCI-H1299 14.50  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C47(1.07)  LDD2171  [5]
 LDCM0102  BDHI 8 Jurkat C47(11.84)  LDD0204  [11]
 LDCM0108  Chloroacetamide HeLa C47(0.00); C193(0.00)  LDD0222  [4]
 LDCM0367  CL1 HEK-293T C193(1.05)  LDD1571  [10]
 LDCM0368  CL10 HEK-293T C193(1.06); C47(0.83)  LDD1572  [10]
 LDCM0369  CL100 HEK-293T C193(0.88)  LDD1573  [10]
 LDCM0370  CL101 HEK-293T C193(1.12)  LDD1574  [10]
 LDCM0371  CL102 HEK-293T C193(1.12)  LDD1575  [10]
 LDCM0372  CL103 HEK-293T C193(1.12)  LDD1576  [10]
 LDCM0373  CL104 HEK-293T C193(1.03)  LDD1577  [10]
 LDCM0374  CL105 HEK-293T C193(0.95)  LDD1578  [10]
 LDCM0375  CL106 HEK-293T C193(0.98)  LDD1579  [10]
 LDCM0376  CL107 HEK-293T C193(1.15)  LDD1580  [10]
 LDCM0377  CL108 HEK-293T C193(1.01)  LDD1581  [10]
 LDCM0378  CL109 HEK-293T C193(1.02)  LDD1582  [10]
 LDCM0379  CL11 HEK-293T C193(1.27); C47(0.76); C28(1.35)  LDD1583  [10]
 LDCM0380  CL110 HEK-293T C193(1.04)  LDD1584  [10]
 LDCM0381  CL111 HEK-293T C193(1.22)  LDD1585  [10]
 LDCM0382  CL112 HEK-293T C193(0.99)  LDD1586  [10]
 LDCM0383  CL113 HEK-293T C193(1.06)  LDD1587  [10]
 LDCM0384  CL114 HEK-293T C193(1.11)  LDD1588  [10]
 LDCM0385  CL115 HEK-293T C193(1.09)  LDD1589  [10]
 LDCM0386  CL116 HEK-293T C193(1.15)  LDD1590  [10]
 LDCM0387  CL117 HEK-293T C193(1.19)  LDD1591  [10]
 LDCM0388  CL118 HEK-293T C193(1.00)  LDD1592  [10]
 LDCM0389  CL119 HEK-293T C193(1.24)  LDD1593  [10]
 LDCM0390  CL12 HEK-293T C47(0.77)  LDD1594  [10]
 LDCM0391  CL120 HEK-293T C193(1.21)  LDD1595  [10]
 LDCM0392  CL121 HEK-293T C193(1.08)  LDD1596  [10]
 LDCM0393  CL122 HEK-293T C193(0.97)  LDD1597  [10]
 LDCM0394  CL123 HEK-293T C193(1.22)  LDD1598  [10]
 LDCM0395  CL124 HEK-293T C193(1.05)  LDD1599  [10]
 LDCM0396  CL125 HEK-293T C193(1.09)  LDD1600  [10]
 LDCM0397  CL126 HEK-293T C193(1.22)  LDD1601  [10]
 LDCM0398  CL127 HEK-293T C193(1.09)  LDD1602  [10]
 LDCM0399  CL128 HEK-293T C193(1.04)  LDD1603  [10]
 LDCM0400  CL13 HEK-293T C193(1.07)  LDD1604  [10]
 LDCM0401  CL14 HEK-293T C193(1.12)  LDD1605  [10]
 LDCM0402  CL15 HEK-293T C193(1.34)  LDD1606  [10]
 LDCM0403  CL16 HEK-293T C193(1.02)  LDD1607  [10]
 LDCM0404  CL17 HEK-293T C193(1.17)  LDD1608  [10]
 LDCM0405  CL18 HEK-293T C193(1.10)  LDD1609  [10]
 LDCM0407  CL2 HEK-293T C193(1.06)  LDD1611  [10]
 LDCM0408  CL20 HEK-293T C193(0.96); C47(1.00)  LDD1612  [10]
 LDCM0409  CL21 HEK-293T C193(0.96); C47(1.00)  LDD1613  [10]
 LDCM0410  CL22 HEK-293T C193(1.12); C47(0.99)  LDD1614  [10]
 LDCM0411  CL23 HEK-293T C193(1.15); C47(1.11); C28(1.32)  LDD1615  [10]
 LDCM0412  CL24 HEK-293T C47(0.86)  LDD1616  [10]
 LDCM0413  CL25 HEK-293T C193(1.05)  LDD1617  [10]
 LDCM0414  CL26 HEK-293T C193(0.94)  LDD1618  [10]
 LDCM0415  CL27 HEK-293T C193(1.13)  LDD1619  [10]
 LDCM0416  CL28 HEK-293T C193(1.06)  LDD1620  [10]
 LDCM0417  CL29 HEK-293T C193(1.02)  LDD1621  [10]
 LDCM0418  CL3 HEK-293T C193(1.22)  LDD1622  [10]
 LDCM0419  CL30 HEK-293T C193(1.04)  LDD1623  [10]
 LDCM0421  CL32 HEK-293T C193(0.97); C47(1.00)  LDD1625  [10]
 LDCM0422  CL33 HEK-293T C193(0.88); C47(0.90)  LDD1626  [10]
 LDCM0423  CL34 HEK-293T C193(1.10); C47(0.98)  LDD1627  [10]
 LDCM0424  CL35 HEK-293T C193(1.34); C47(1.00); C28(1.36)  LDD1628  [10]
 LDCM0425  CL36 HEK-293T C47(0.86)  LDD1629  [10]
 LDCM0426  CL37 HEK-293T C193(1.10)  LDD1630  [10]
 LDCM0428  CL39 HEK-293T C193(1.19)  LDD1632  [10]
 LDCM0429  CL4 HEK-293T C193(0.95)  LDD1633  [10]
 LDCM0430  CL40 HEK-293T C193(1.06)  LDD1634  [10]
 LDCM0431  CL41 HEK-293T C193(1.00)  LDD1635  [10]
 LDCM0432  CL42 HEK-293T C193(1.19)  LDD1636  [10]
 LDCM0434  CL44 HEK-293T C193(1.04); C47(0.93)  LDD1638  [10]
 LDCM0435  CL45 HEK-293T C193(0.94); C47(1.04)  LDD1639  [10]
 LDCM0436  CL46 HEK-293T C193(1.07); C47(0.97)  LDD1640  [10]
 LDCM0437  CL47 HEK-293T C193(1.38); C47(1.70); C28(1.01)  LDD1641  [10]
 LDCM0438  CL48 HEK-293T C47(0.83)  LDD1642  [10]
 LDCM0439  CL49 HEK-293T C193(1.24)  LDD1643  [10]
 LDCM0440  CL5 HEK-293T C193(1.06)  LDD1644  [10]
 LDCM0441  CL50 HEK-293T C193(1.28)  LDD1645  [10]
 LDCM0443  CL52 HEK-293T C193(1.13)  LDD1646  [10]
 LDCM0444  CL53 HEK-293T C193(1.16)  LDD1647  [10]
 LDCM0445  CL54 HEK-293T C193(1.17)  LDD1648  [10]
 LDCM0447  CL56 HEK-293T C193(0.95); C47(1.01)  LDD1650  [10]
 LDCM0448  CL57 HEK-293T C193(1.01); C47(0.95)  LDD1651  [10]
 LDCM0449  CL58 HEK-293T C193(1.08); C47(0.90)  LDD1652  [10]
 LDCM0450  CL59 HEK-293T C193(1.19); C47(0.99); C28(1.07)  LDD1653  [10]
 LDCM0451  CL6 HEK-293T C193(1.37)  LDD1654  [10]
 LDCM0452  CL60 HEK-293T C47(0.93)  LDD1655  [10]
 LDCM0453  CL61 HEK-293T C193(1.09)  LDD1656  [10]
 LDCM0454  CL62 HEK-293T C193(1.16)  LDD1657  [10]
 LDCM0455  CL63 HEK-293T C193(1.15)  LDD1658  [10]
 LDCM0456  CL64 HEK-293T C193(0.94)  LDD1659  [10]
 LDCM0457  CL65 HEK-293T C193(1.06)  LDD1660  [10]
 LDCM0458  CL66 HEK-293T C193(1.15)  LDD1661  [10]
 LDCM0460  CL68 HEK-293T C193(1.05); C47(1.07)  LDD1663  [10]
 LDCM0461  CL69 HEK-293T C193(1.06); C47(0.94)  LDD1664  [10]
 LDCM0463  CL70 HEK-293T C193(0.99); C47(0.97)  LDD1666  [10]
 LDCM0464  CL71 HEK-293T C193(1.08); C47(1.39); C28(1.08)  LDD1667  [10]
 LDCM0465  CL72 HEK-293T C47(0.88)  LDD1668  [10]
 LDCM0466  CL73 HEK-293T C193(0.92)  LDD1669  [10]
 LDCM0467  CL74 HEK-293T C193(1.01)  LDD1670  [10]
 LDCM0469  CL76 HEK-293T C193(1.10)  LDD1672  [10]
 LDCM0470  CL77 HEK-293T C193(1.07)  LDD1673  [10]
 LDCM0471  CL78 HEK-293T C193(1.31)  LDD1674  [10]
 LDCM0473  CL8 HEK-293T C193(1.12); C47(0.97)  LDD1676  [10]
 LDCM0474  CL80 HEK-293T C193(0.99); C47(1.06)  LDD1677  [10]
 LDCM0475  CL81 HEK-293T C193(1.06); C47(1.00)  LDD1678  [10]
 LDCM0476  CL82 HEK-293T C193(1.08); C47(0.99)  LDD1679  [10]
 LDCM0477  CL83 HEK-293T C193(1.12); C47(1.21); C28(1.01)  LDD1680  [10]
 LDCM0478  CL84 HEK-293T C47(0.87)  LDD1681  [10]
 LDCM0479  CL85 HEK-293T C193(1.23)  LDD1682  [10]
 LDCM0480  CL86 HEK-293T C193(1.03)  LDD1683  [10]
 LDCM0481  CL87 HEK-293T C193(1.10)  LDD1684  [10]
 LDCM0482  CL88 HEK-293T C193(1.15)  LDD1685  [10]
 LDCM0483  CL89 HEK-293T C193(1.05)  LDD1686  [10]
 LDCM0484  CL9 HEK-293T C193(0.98); C47(0.93)  LDD1687  [10]
 LDCM0485  CL90 HEK-293T C193(1.35)  LDD1688  [10]
 LDCM0487  CL92 HEK-293T C193(0.97); C47(1.06)  LDD1690  [10]
 LDCM0488  CL93 HEK-293T C193(0.91); C47(0.96)  LDD1691  [10]
 LDCM0489  CL94 HEK-293T C193(0.98); C47(1.03)  LDD1692  [10]
 LDCM0490  CL95 HEK-293T C193(1.11); C47(0.95); C28(0.86)  LDD1693  [10]
 LDCM0491  CL96 HEK-293T C47(0.86)  LDD1694  [10]
 LDCM0492  CL97 HEK-293T C193(1.04)  LDD1695  [10]
 LDCM0493  CL98 HEK-293T C193(1.15)  LDD1696  [10]
 LDCM0494  CL99 HEK-293T C193(1.15)  LDD1697  [10]
 LDCM0495  E2913 HEK-293T C193(1.12)  LDD1698  [10]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C5(1.85); C47(1.07)  LDD1702  [2]
 LDCM0468  Fragment33 HEK-293T C193(1.03)  LDD1671  [10]
 LDCM0427  Fragment51 HEK-293T C193(1.22)  LDD1631  [10]
 LDCM0107  IAA HeLa N.A.  LDD0221  [4]
 LDCM0022  KB02 HCT 116 C193(1.26)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C193(1.55)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C193(1.23)  LDD0082  [5]
 LDCM0109  NEM HeLa N.A.  LDD0232  [4]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C47(0.95)  LDD2093  [2]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C47(1.21)  LDD2107  [2]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C47(1.00)  LDD2109  [2]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C47(1.01)  LDD2111  [2]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C47(1.43)  LDD2119  [2]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C47(1.04)  LDD2137  [2]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C47(1.05)  LDD2140  [2]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C47(0.96)  LDD2146  [2]
 LDCM0021  THZ1 HCT 116 C47(1.07)  LDD2173  [5]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.