Details of the Target

General Information of Target

Target ID LDTP11184
Target Name THAP domain-containing protein 7 (THAP7)
Gene Name THAP7
Gene ID 80764
Synonyms
THAP domain-containing protein 7
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
Download
Sequence
MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYV
LALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIR
VRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEE
EEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors.
Uniprot ID
Q9BT49
Ensemble ID
ENST00000215742.9
HGNC ID
HGNC:23190

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
BTD
 Probe Info  		C261(0.80)  LDD2089  [1]
IPM
 Probe Info  		C261(2.18)  LDD1701  [1]
DBIA
 Probe Info  		C43(1.31)  LDD0531  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C43(1.31)  LDD0531  [2]
 LDCM0215  AC10 HEK-293T C43(0.78)  LDD0813  [2]
 LDCM0226  AC11 HEK-293T C43(0.83)  LDD0824  [2]
 LDCM0237  AC12 HEK-293T C43(0.68)  LDD0835  [2]
 LDCM0259  AC14 HEK-293T C43(0.91)  LDD0857  [2]
 LDCM0263  AC143 HEK-293T C43(0.97)  LDD0861  [2]
 LDCM0264  AC144 HEK-293T C43(0.96)  LDD0862  [2]
 LDCM0265  AC145 HEK-293T C43(1.01)  LDD0863  [2]
 LDCM0266  AC146 HEK-293T C43(0.95)  LDD0864  [2]
 LDCM0267  AC147 HEK-293T C43(0.92)  LDD0865  [2]
 LDCM0268  AC148 HEK-293T C43(0.94)  LDD0866  [2]
 LDCM0269  AC149 HEK-293T C43(0.90)  LDD0867  [2]
 LDCM0270  AC15 HEK-293T C43(0.70)  LDD0868  [2]
 LDCM0271  AC150 HEK-293T C43(0.88)  LDD0869  [2]
 LDCM0272  AC151 HEK-293T C43(0.88)  LDD0870  [2]
 LDCM0273  AC152 HEK-293T C43(0.97)  LDD0871  [2]
 LDCM0274  AC153 HEK-293T C43(0.94)  LDD0872  [2]
 LDCM0621  AC154 HEK-293T C43(0.87)  LDD2162  [2]
 LDCM0622  AC155 HEK-293T C43(0.97)  LDD2163  [2]
 LDCM0623  AC156 HEK-293T C43(0.86)  LDD2164  [2]
 LDCM0624  AC157 HEK-293T C43(0.92)  LDD2165  [2]
 LDCM0276  AC17 HEK-293T C43(0.59)  LDD0874  [2]
 LDCM0277  AC18 HEK-293T C43(0.84)  LDD0875  [2]
 LDCM0278  AC19 HEK-293T C43(0.69)  LDD0876  [2]
 LDCM0279  AC2 HCT 116 C43(1.13)  LDD0596  [2]
 LDCM0280  AC20 HEK-293T C43(1.08)  LDD0878  [2]
 LDCM0281  AC21 HEK-293T C43(1.21)  LDD0879  [2]
 LDCM0282  AC22 HEK-293T C43(1.12)  LDD0880  [2]
 LDCM0283  AC23 HEK-293T C43(1.36)  LDD0881  [2]
 LDCM0284  AC24 HEK-293T C43(1.38)  LDD0882  [2]
 LDCM0285  AC25 HCT 116 C43(0.78)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C43(0.71)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C43(0.66)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C43(0.75)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C43(0.61)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C43(1.15)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C43(0.64)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C43(0.87)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C43(0.83)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C43(0.61)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C43(0.95)  LDD0612  [2]
 LDCM0296  AC35 HEK-293T C43(1.04)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C43(1.24)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C43(1.38)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C43(1.32)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C43(0.96)  LDD0898  [2]
 LDCM0301  AC4 HCT 116 C43(1.36)  LDD0618  [2]
 LDCM0302  AC40 HEK-293T C43(1.14)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C43(1.23)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C43(1.03)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C43(1.26)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C43(1.14)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C43(1.06)  LDD0905  [2]
 LDCM0308  AC46 HEK-293T C43(1.30)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C43(1.11)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C43(1.05)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C43(1.08)  LDD0909  [2]
 LDCM0312  AC5 HCT 116 C43(1.35)  LDD0629  [2]
 LDCM0313  AC50 HEK-293T C43(1.18)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C43(1.21)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C43(1.18)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C43(1.22)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C43(1.19)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C43(1.41)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C43(1.18)  LDD0917  [2]
 LDCM0323  AC6 HEK-293T C43(0.97)  LDD0921  [2]
 LDCM0328  AC64 HEK-293T C147(1.04)  LDD1567  [4]
 LDCM0332  AC68 HCT 116 C43(1.00)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C43(0.97)  LDD0650  [2]
 LDCM0334  AC7 HEK-293T C43(0.76)  LDD0932  [2]
 LDCM0335  AC70 HCT 116 C43(1.26)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C43(0.92)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C43(1.11)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C43(1.25)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C43(1.06)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C43(1.15)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C43(0.89)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C43(0.91)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C43(0.95)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C43(1.00)  LDD0661  [2]
 LDCM0345  AC8 HEK-293T C43(0.76)  LDD0943  [2]
 LDCM0346  AC80 HCT 116 C43(0.82)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C43(1.01)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C43(0.79)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C43(1.54)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C43(1.39)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C43(1.35)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C43(1.32)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C43(1.12)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C43(1.32)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C43(1.27)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C43(1.02)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C43(1.58)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C43(1.59)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C43(1.30)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C43(1.25)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C43(1.37)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C43(1.36)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C43(1.60)  LDD0681  [2]
 LDCM0248  AKOS034007472 HEK-293T C43(0.86)  LDD0846  [2]
 LDCM0356  AKOS034007680 HEK-293T C43(0.71)  LDD0954  [2]
 LDCM0275  AKOS034007705 HEK-293T C43(1.02)  LDD0873  [2]
 LDCM0367  CL1 HEK-293T C43(1.07)  LDD0965  [2]
 LDCM0368  CL10 HEK-293T C43(1.04)  LDD0966  [2]
 LDCM0369  CL100 HCT 116 C43(1.38)  LDD0686  [2]
 LDCM0370  CL101 HEK-293T C43(0.96)  LDD0968  [2]
 LDCM0371  CL102 HEK-293T C43(1.43)  LDD0969  [2]
 LDCM0372  CL103 HEK-293T C43(0.75)  LDD0970  [2]
 LDCM0373  CL104 HEK-293T C43(0.85)  LDD0971  [2]
 LDCM0374  CL105 HEK-293T C43(1.48)  LDD0972  [2]
 LDCM0375  CL106 HEK-293T C43(0.79)  LDD0973  [2]
 LDCM0376  CL107 HEK-293T C43(0.97)  LDD0974  [2]
 LDCM0377  CL108 HEK-293T C43(0.63)  LDD0975  [2]
 LDCM0378  CL109 HEK-293T C43(1.25)  LDD0976  [2]
 LDCM0379  CL11 HEK-293T C43(1.26)  LDD0977  [2]
 LDCM0380  CL110 HEK-293T C43(0.88)  LDD0978  [2]
 LDCM0381  CL111 HEK-293T C43(1.59)  LDD0979  [2]
 LDCM0382  CL112 HCT 116 C43(0.68)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C43(0.81)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C43(0.85)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C43(0.77)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C43(0.77)  LDD0703  [2]
 LDCM0387  CL117 HEK-293T C43(1.07)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C43(1.21)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C43(1.06)  LDD0987  [2]
 LDCM0390  CL12 HEK-293T C43(0.98)  LDD0988  [2]
 LDCM0391  CL120 HEK-293T C43(1.09)  LDD0989  [2]
 LDCM0392  CL121 HEK-293T C43(1.19)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C43(1.00)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C43(1.48)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C43(1.21)  LDD0993  [2]
 LDCM0397  CL126 HEK-293T C11(1.11)  LDD1601  [4]
 LDCM0398  CL127 HEK-293T C11(0.88)  LDD1602  [4]
 LDCM0400  CL13 HEK-293T C43(0.98)  LDD0998  [2]
 LDCM0401  CL14 HEK-293T C43(0.91)  LDD0999  [2]
 LDCM0402  CL15 HEK-293T C43(1.03)  LDD1000  [2]
 LDCM0403  CL16 HCT 116 C43(1.01)  LDD0720  [2]
 LDCM0407  CL2 HEK-293T C43(1.05)  LDD1005  [2]
 LDCM0412  CL24 HEK-293T C147(1.11)  LDD1616  [4]
 LDCM0414  CL26 HEK-293T C11(1.06)  LDD1618  [4]
 LDCM0415  CL27 HEK-293T C11(1.11)  LDD1619  [4]
 LDCM0418  CL3 HEK-293T C43(0.97)  LDD1016  [2]
 LDCM0421  CL32 HCT 116 C43(1.01)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C43(1.10)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C43(0.94)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C43(0.94)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C43(0.92)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C43(1.09)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C43(0.86)  LDD0745  [2]
 LDCM0429  CL4 HEK-293T C43(0.99)  LDD1027  [2]
 LDCM0430  CL40 HCT 116 C43(1.01)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C43(0.95)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C43(1.14)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C43(1.02)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C43(0.93)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C43(1.03)  LDD0752  [2]
 LDCM0436  CL46 HEK-293T C43(0.80)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C43(0.84)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C43(0.83)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C43(0.82)  LDD1037  [2]
 LDCM0440  CL5 HEK-293T C43(1.15)  LDD1038  [2]
 LDCM0441  CL50 HEK-293T C43(0.89)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C43(1.10)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C43(0.80)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C43(1.12)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C43(1.26)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C43(0.87)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C43(0.91)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C43(1.31)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C43(0.96)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C43(0.87)  LDD1048  [2]
 LDCM0451  CL6 HEK-293T C43(1.12)  LDD1049  [2]
 LDCM0452  CL60 HEK-293T C43(0.91)  LDD1050  [2]
 LDCM0453  CL61 HCT 116 C43(1.03)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C43(1.01)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C43(0.99)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C43(1.25)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C43(1.00)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C43(1.35)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C43(1.44)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C43(1.10)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C43(1.20)  LDD0778  [2]
 LDCM0462  CL7 HEK-293T C43(1.04)  LDD1060  [2]
 LDCM0463  CL70 HCT 116 C43(1.25)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C43(1.12)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C43(1.06)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C43(1.14)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C43(1.11)  LDD0784  [2]
 LDCM0473  CL8 HEK-293T C43(1.30)  LDD1071  [2]
 LDCM0478  CL84 HEK-293T C147(1.15)  LDD1681  [4]
 LDCM0480  CL86 HEK-293T C11(1.05)  LDD1683  [4]
 LDCM0481  CL87 HEK-293T C11(0.80)  LDD1684  [4]
 LDCM0484  CL9 HEK-293T C43(1.41)  LDD1082  [2]
 LDCM0486  CL91 HCT 116 C43(1.05)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C43(1.12)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C43(1.29)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C43(1.26)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C43(1.29)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C43(1.21)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C43(1.29)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C43(1.29)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C43(1.33)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C11(0.97)  LDD1698  [4]
 LDCM0468  Fragment33 HCT 116 C43(1.02)  LDD0785  [2]
 LDCM0427  Fragment51 HCT 116 C43(0.94)  LDD0744  [2]
 LDCM0023  KB03 MDA-MB-231 C261(2.18)  LDD1701  [1]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C261(0.80)  LDD2089  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) 2-oxoacid dehydrogenase family P36957
Deubiquitinase DESI2 (DESI2) DeSI family Q9BSY9
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Ubiquitin thioesterase ZRANB1 (ZRANB1) Peptidase C64 family Q9UGI0
Serine/threonine-protein kinase Nek7 (NEK7) NEK Ser/Thr protein kinase family Q8TDX7
TNF receptor-associated factor 2 (TRAF2) TNF receptor-associated factor family Q12933
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Fibronectin type III and SPRY domain-containing protein 2 (FSD2) . A1L4K1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) . Q13526
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Calreticulin (CALR) Calreticulin family P27797
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Cadherin-1 (CDH1) . P12830
Transcription factor
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-A1 (HOXA1) Antp homeobox family P49639
PHD finger protein 19 (PHF19) Polycomblike family Q5T6S3
THAP domain-containing protein 7 (THAP7) . Q9BT49
Other
Click To Hide/Show 32 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1) ATG8 family Q9H0R8
Cyclin-D1-binding protein 1 (CCNDBP1) CCNDBP1 family O95273
Cyclin-dependent kinase 5 activator 1 (CDK5R1) Cyclin-dependent kinase 5 activator family Q15078
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2) Fibulin family O95967
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Keratin, type I cytoskeletal 27 (KRT27) Intermediate filament family Q7Z3Y8
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Keratin-associated protein 1-3 (KRTAP1-3) KRTAP type 1 family Q8IUG1
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Protein LDOC1 (LDOC1) LDOC1 family O95751
Leucine zipper putative tumor suppressor 2 (LZTS2) LZTS2 family Q9BRK4
Protein mago nashi homolog 2 (MAGOHB) Mago nashi family Q96A72
Colorectal mutant cancer protein (MCC) MCC family P23508
Microtubule-associated tumor suppressor candidate 2 (MTUS2) MTUS1 family Q5JR59
Notch homolog 2 N-terminal-like protein A (NOTCH2NLA) NOTCH family Q7Z3S9
Notch homolog 2 N-terminal-like protein C (NOTCH2NLC) NOTCH family P0DPK4
Protein SET (SET) Nucleosome assembly protein (NAP) family Q01105
Paraneoplastic antigen Ma2 (PNMA2) PNMA family Q9UL42
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
TNF receptor-associated factor 5 (TRAF5) TNF receptor-associated factor family O00463
Tropomyosin alpha-3 chain (TPM3) Tropomyosin family P06753
Four and a half LIM domains protein 3 (FHL3) . Q13643
Keratin-associated protein 17-1 (KRTAP17-1) . Q9BYP8
Polyhomeotic-like protein 2 (PHC2) . Q8IXK0
PRKCA-binding protein (PICK1) . Q9NRD5
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (ANKRD28) . O15084
TNF receptor-associated factor 1 (TRAF1) . Q13077

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402