Details of the Target

General Information of Target

Target ID LDTP05685
Target Name Transmembrane protein 115 (TMEM115)
Gene Name TMEM115
Gene ID 11070
Synonyms
PL6; Transmembrane protein 115; Placental protein 6; Protein PL6
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MQRALPGARQHLGAILASASVVVKALCAAVLFLYLLSFAVDTGCLAVTPGYLFPPNFWIW
TLATHGLMEQHVWDVAISLTTVVVAGRLLEPLWGALELLIFFSVVNVSVGLLGAFAYLLT
YMASFNLVYLFTVRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVSVMPMLLLALLLLL
RLATLLQSPALASYGFGLLSSWVYLRFYQRHSRGRGDMADHFAFATFFPEILQPVVGLLA
NLVHSLLVKVKICQKTVKRYDVGAPSSITISLPGTDPQDAERRRQLALKALNERLKRVED
QSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSLITFEAAPPTL
Target Bioclass
Other
Family
TMEM115 family
Subcellular location
Golgi apparatus, Golgi stack membrane
Function May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.
Uniprot ID
Q12893
Ensemble ID
ENST00000266025.4
HGNC ID
HGNC:30055

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ONAyne
 Probe Info  		K289(6.88)  LDD0274  [1]
STPyne
 Probe Info  		K289(8.37)  LDD0277  [1]
IPM
 Probe Info  		C156(3.37)  LDD1701  [2]
DBIA
 Probe Info  		C156(0.97)  LDD0828  [3]
AOyne
 Probe Info  		15.00  LDD0443  [4]
PAL-AfBPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C040
 Probe Info  		6.73  LDD1740  [5]
C112
 Probe Info  		18.51  LDD1799  [5]
C228
 Probe Info  		15.35  LDD1901  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C156(1.03)  LDD1507  [6]
 LDCM0215  AC10 HEK-293T C156(0.95)  LDD1508  [6]
 LDCM0226  AC11 HEK-293T C156(0.99)  LDD1509  [6]
 LDCM0230  AC113 HEK-293T C156(0.97)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C156(1.01)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C156(1.24)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C156(1.20)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C156(1.18)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C156(1.19)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C156(1.13)  LDD0834  [3]
 LDCM0237  AC12 HEK-293T C156(0.97)  LDD1510  [6]
 LDCM0238  AC120 HEK-293T C156(0.94)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C156(1.14)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C156(0.98)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C156(0.94)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C156(1.16)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C156(0.95)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C156(1.03)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C156(1.03)  LDD0843  [3]
 LDCM0259  AC14 HEK-293T C156(0.98)  LDD1512  [6]
 LDCM0263  AC143 HEK-293T C156(0.79)  LDD0861  [3]
 LDCM0264  AC144 HEK-293T C156(0.77)  LDD0862  [3]
 LDCM0265  AC145 HEK-293T C156(0.44)  LDD0863  [3]
 LDCM0266  AC146 HEK-293T C156(0.65)  LDD0864  [3]
 LDCM0267  AC147 HEK-293T C156(0.44)  LDD0865  [3]
 LDCM0268  AC148 HEK-293T C156(0.35)  LDD0866  [3]
 LDCM0269  AC149 HEK-293T C156(0.60)  LDD0867  [3]
 LDCM0270  AC15 HEK-293T C156(1.00)  LDD1513  [6]
 LDCM0271  AC150 HEK-293T C156(0.39)  LDD0869  [3]
 LDCM0272  AC151 HEK-293T C156(0.37)  LDD0870  [3]
 LDCM0273  AC152 HEK-293T C156(0.76)  LDD0871  [3]
 LDCM0274  AC153 HEK-293T C156(1.18)  LDD0872  [3]
 LDCM0621  AC154 HEK-293T C156(0.76)  LDD2162  [3]
 LDCM0622  AC155 HEK-293T C156(0.97)  LDD2163  [3]
 LDCM0623  AC156 HEK-293T C156(0.71)  LDD2164  [3]
 LDCM0624  AC157 HEK-293T C156(0.62)  LDD2165  [3]
 LDCM0276  AC17 PaTu 8988t C156(0.93)  LDD1155  [3]
 LDCM0277  AC18 PaTu 8988t C156(1.60)  LDD1156  [3]
 LDCM0278  AC19 PaTu 8988t C156(1.36)  LDD1157  [3]
 LDCM0279  AC2 HEK-293T C156(0.88)  LDD1518  [6]
 LDCM0280  AC20 PaTu 8988t C156(1.07)  LDD1159  [3]
 LDCM0281  AC21 PaTu 8988t C156(1.26)  LDD1160  [3]
 LDCM0282  AC22 PaTu 8988t C156(0.93)  LDD1161  [3]
 LDCM0283  AC23 PaTu 8988t C156(1.16)  LDD1162  [3]
 LDCM0284  AC24 PaTu 8988t C156(1.40)  LDD1163  [3]
 LDCM0285  AC25 PaTu 8988t C156(0.77)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C156(0.72)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C156(0.84)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C156(1.05)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C156(1.03)  LDD1168  [3]
 LDCM0290  AC3 HEK-293T C156(0.99)  LDD1529  [6]
 LDCM0291  AC30 PaTu 8988t C156(0.91)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C156(0.87)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C156(0.90)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C156(0.86)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C156(0.81)  LDD1174  [3]
 LDCM0296  AC35 PaTu 8988t C156(0.74)  LDD1175  [3]
 LDCM0297  AC36 PaTu 8988t C156(0.87)  LDD1176  [3]
 LDCM0298  AC37 PaTu 8988t C156(0.89)  LDD1177  [3]
 LDCM0299  AC38 PaTu 8988t C156(0.91)  LDD1178  [3]
 LDCM0300  AC39 PaTu 8988t C156(1.21)  LDD1179  [3]
 LDCM0301  AC4 HEK-293T C156(0.93)  LDD1540  [6]
 LDCM0302  AC40 PaTu 8988t C156(1.01)  LDD1181  [3]
 LDCM0303  AC41 PaTu 8988t C156(0.94)  LDD1182  [3]
 LDCM0304  AC42 PaTu 8988t C156(0.92)  LDD1183  [3]
 LDCM0305  AC43 PaTu 8988t C156(1.09)  LDD1184  [3]
 LDCM0306  AC44 PaTu 8988t C156(1.04)  LDD1185  [3]
 LDCM0307  AC45 PaTu 8988t C156(1.06)  LDD1186  [3]
 LDCM0308  AC46 PaTu 8988t C156(1.45)  LDD1187  [3]
 LDCM0309  AC47 PaTu 8988t C156(1.66)  LDD1188  [3]
 LDCM0310  AC48 PaTu 8988t C156(1.27)  LDD1189  [3]
 LDCM0311  AC49 PaTu 8988t C156(1.19)  LDD1190  [3]
 LDCM0312  AC5 HEK-293T C156(0.98)  LDD1551  [6]
 LDCM0313  AC50 PaTu 8988t C156(1.52)  LDD1192  [3]
 LDCM0314  AC51 PaTu 8988t C156(1.63)  LDD1193  [3]
 LDCM0315  AC52 PaTu 8988t C156(1.30)  LDD1194  [3]
 LDCM0316  AC53 PaTu 8988t C156(1.21)  LDD1195  [3]
 LDCM0317  AC54 PaTu 8988t C156(1.85)  LDD1196  [3]
 LDCM0318  AC55 PaTu 8988t C156(1.60)  LDD1197  [3]
 LDCM0319  AC56 PaTu 8988t C156(1.67)  LDD1198  [3]
 LDCM0320  AC57 HEK-293T C156(1.18)  LDD0918  [3]
 LDCM0321  AC58 HEK-293T C156(1.03)  LDD0919  [3]
 LDCM0322  AC59 HEK-293T C156(1.14)  LDD0920  [3]
 LDCM0323  AC6 HEK-293T C156(0.93)  LDD1562  [6]
 LDCM0324  AC60 HEK-293T C156(0.88)  LDD0922  [3]
 LDCM0325  AC61 HEK-293T C156(1.09)  LDD0923  [3]
 LDCM0326  AC62 HEK-293T C156(1.04)  LDD0924  [3]
 LDCM0327  AC63 HEK-293T C156(1.08)  LDD0925  [3]
 LDCM0328  AC64 HEK-293T C156(1.29)  LDD0926  [3]
 LDCM0329  AC65 HEK-293T C156(1.17)  LDD0927  [3]
 LDCM0330  AC66 HEK-293T C156(1.21)  LDD0928  [3]
 LDCM0331  AC67 HEK-293T C156(1.10)  LDD0929  [3]
 LDCM0332  AC68 HEK-293T C156(0.91)  LDD0930  [3]
 LDCM0333  AC69 HEK-293T C156(1.23)  LDD0931  [3]
 LDCM0334  AC7 HEK-293T C156(0.98)  LDD1568  [6]
 LDCM0335  AC70 HEK-293T C156(1.09)  LDD0933  [3]
 LDCM0336  AC71 HEK-293T C156(0.91)  LDD0934  [3]
 LDCM0337  AC72 HEK-293T C156(1.07)  LDD0935  [3]
 LDCM0338  AC73 HEK-293T C156(0.99)  LDD0936  [3]
 LDCM0339  AC74 HEK-293T C156(1.08)  LDD0937  [3]
 LDCM0340  AC75 HEK-293T C156(0.81)  LDD0938  [3]
 LDCM0341  AC76 HEK-293T C156(0.78)  LDD0939  [3]
 LDCM0342  AC77 HEK-293T C156(0.91)  LDD0940  [3]
 LDCM0343  AC78 HEK-293T C156(0.82)  LDD0941  [3]
 LDCM0344  AC79 HEK-293T C156(0.92)  LDD0942  [3]
 LDCM0345  AC8 HEK-293T C156(0.92)  LDD1569  [6]
 LDCM0346  AC80 HEK-293T C156(0.73)  LDD0944  [3]
 LDCM0347  AC81 HEK-293T C156(0.83)  LDD0945  [3]
 LDCM0348  AC82 HEK-293T C156(0.92)  LDD0946  [3]
 LDCM0349  AC83 PaTu 8988t C156(0.92)  LDD1228  [3]
 LDCM0350  AC84 PaTu 8988t C156(1.16)  LDD1229  [3]
 LDCM0351  AC85 PaTu 8988t C156(0.87)  LDD1230  [3]
 LDCM0352  AC86 PaTu 8988t C156(0.80)  LDD1231  [3]
 LDCM0353  AC87 PaTu 8988t C156(1.06)  LDD1232  [3]
 LDCM0354  AC88 PaTu 8988t C156(0.97)  LDD1233  [3]
 LDCM0355  AC89 PaTu 8988t C156(1.10)  LDD1234  [3]
 LDCM0357  AC90 PaTu 8988t C156(0.68)  LDD1236  [3]
 LDCM0358  AC91 PaTu 8988t C156(0.70)  LDD1237  [3]
 LDCM0359  AC92 PaTu 8988t C156(1.06)  LDD1238  [3]
 LDCM0360  AC93 PaTu 8988t C156(0.73)  LDD1239  [3]
 LDCM0361  AC94 PaTu 8988t C156(0.78)  LDD1240  [3]
 LDCM0362  AC95 PaTu 8988t C156(0.95)  LDD1241  [3]
 LDCM0363  AC96 PaTu 8988t C156(0.87)  LDD1242  [3]
 LDCM0364  AC97 PaTu 8988t C156(1.08)  LDD1243  [3]
 LDCM0248  AKOS034007472 HEK-293T C156(0.96)  LDD1511  [6]
 LDCM0356  AKOS034007680 HEK-293T C156(0.99)  LDD1570  [6]
 LDCM0275  AKOS034007705 HEK-293T C156(1.00)  LDD1514  [6]
 LDCM0367  CL1 PaTu 8988t C156(0.87)  LDD1246  [3]
 LDCM0368  CL10 PaTu 8988t C156(1.43)  LDD1247  [3]
 LDCM0369  CL100 HEK-293T C156(1.14)  LDD1573  [6]
 LDCM0370  CL101 HEK-293T C156(0.99)  LDD1574  [6]
 LDCM0371  CL102 HEK-293T C156(1.26)  LDD1575  [6]
 LDCM0372  CL103 HEK-293T C156(0.96)  LDD1576  [6]
 LDCM0373  CL104 HEK-293T C156(1.02)  LDD1577  [6]
 LDCM0374  CL105 PaTu 8988t C156(1.01)  LDD1253  [3]
 LDCM0375  CL106 PaTu 8988t C156(1.27)  LDD1254  [3]
 LDCM0376  CL107 PaTu 8988t C156(1.65)  LDD1255  [3]
 LDCM0377  CL108 PaTu 8988t C156(1.08)  LDD1256  [3]
 LDCM0378  CL109 PaTu 8988t C156(1.30)  LDD1257  [3]
 LDCM0379  CL11 PaTu 8988t C156(0.98)  LDD1258  [3]
 LDCM0380  CL110 PaTu 8988t C156(1.26)  LDD1259  [3]
 LDCM0381  CL111 PaTu 8988t C156(1.55)  LDD1260  [3]
 LDCM0382  CL112 PaTu 8988t C156(0.79)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C156(0.85)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C156(1.02)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C156(0.82)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C156(0.92)  LDD1265  [3]
 LDCM0387  CL117 PaTu 8988t C156(0.88)  LDD1266  [3]
 LDCM0388  CL118 PaTu 8988t C156(1.03)  LDD1267  [3]
 LDCM0389  CL119 PaTu 8988t C156(1.15)  LDD1268  [3]
 LDCM0390  CL12 PaTu 8988t C156(1.14)  LDD1269  [3]
 LDCM0391  CL120 PaTu 8988t C156(0.80)  LDD1270  [3]
 LDCM0392  CL121 PaTu 8988t C156(1.43)  LDD1271  [3]
 LDCM0393  CL122 PaTu 8988t C156(1.38)  LDD1272  [3]
 LDCM0394  CL123 PaTu 8988t C156(1.60)  LDD1273  [3]
 LDCM0395  CL124 PaTu 8988t C156(1.78)  LDD1274  [3]
 LDCM0396  CL125 HEK-293T C156(1.18)  LDD0994  [3]
 LDCM0397  CL126 HEK-293T C156(1.11)  LDD0995  [3]
 LDCM0398  CL127 HEK-293T C156(1.07)  LDD0996  [3]
 LDCM0399  CL128 HEK-293T C156(1.13)  LDD0997  [3]
 LDCM0400  CL13 PaTu 8988t C156(1.73)  LDD1279  [3]
 LDCM0401  CL14 PaTu 8988t C156(1.27)  LDD1280  [3]
 LDCM0402  CL15 PaTu 8988t C156(1.18)  LDD1281  [3]
 LDCM0403  CL16 PaTu 8988t C156(0.77)  LDD1282  [3]
 LDCM0404  CL17 PaTu 8988t C156(0.91)  LDD1283  [3]
 LDCM0405  CL18 PaTu 8988t C156(1.00)  LDD1284  [3]
 LDCM0406  CL19 PaTu 8988t C156(0.71)  LDD1285  [3]
 LDCM0407  CL2 PaTu 8988t C156(1.08)  LDD1286  [3]
 LDCM0408  CL20 PaTu 8988t C156(0.79)  LDD1287  [3]
 LDCM0409  CL21 PaTu 8988t C156(0.91)  LDD1288  [3]
 LDCM0410  CL22 PaTu 8988t C156(0.79)  LDD1289  [3]
 LDCM0411  CL23 PaTu 8988t C156(1.01)  LDD1290  [3]
 LDCM0412  CL24 PaTu 8988t C156(0.81)  LDD1291  [3]
 LDCM0413  CL25 PaTu 8988t C156(0.84)  LDD1292  [3]
 LDCM0414  CL26 PaTu 8988t C156(0.99)  LDD1293  [3]
 LDCM0415  CL27 PaTu 8988t C156(0.92)  LDD1294  [3]
 LDCM0416  CL28 PaTu 8988t C156(1.09)  LDD1295  [3]
 LDCM0417  CL29 PaTu 8988t C156(0.76)  LDD1296  [3]
 LDCM0418  CL3 PaTu 8988t C156(1.15)  LDD1297  [3]
 LDCM0419  CL30 PaTu 8988t C156(0.93)  LDD1298  [3]
 LDCM0420  CL31 PaTu 8988t C156(1.19)  LDD1299  [3]
 LDCM0421  CL32 PaTu 8988t C156(1.01)  LDD1300  [3]
 LDCM0422  CL33 PaTu 8988t C156(1.40)  LDD1301  [3]
 LDCM0423  CL34 PaTu 8988t C156(1.65)  LDD1302  [3]
 LDCM0424  CL35 PaTu 8988t C156(1.20)  LDD1303  [3]
 LDCM0425  CL36 PaTu 8988t C156(0.99)  LDD1304  [3]
 LDCM0426  CL37 PaTu 8988t C156(1.52)  LDD1305  [3]
 LDCM0428  CL39 PaTu 8988t C156(1.26)  LDD1307  [3]
 LDCM0429  CL4 PaTu 8988t C156(1.03)  LDD1308  [3]
 LDCM0430  CL40 PaTu 8988t C156(1.00)  LDD1309  [3]
 LDCM0431  CL41 PaTu 8988t C156(1.12)  LDD1310  [3]
 LDCM0432  CL42 PaTu 8988t C156(1.91)  LDD1311  [3]
 LDCM0433  CL43 PaTu 8988t C156(1.51)  LDD1312  [3]
 LDCM0434  CL44 PaTu 8988t C156(1.64)  LDD1313  [3]
 LDCM0435  CL45 PaTu 8988t C156(1.13)  LDD1314  [3]
 LDCM0436  CL46 HEK-293T C156(0.73)  LDD1034  [3]
 LDCM0437  CL47 HEK-293T C156(0.76)  LDD1035  [3]
 LDCM0438  CL48 HEK-293T C156(0.92)  LDD1036  [3]
 LDCM0439  CL49 HEK-293T C156(0.89)  LDD1037  [3]
 LDCM0440  CL5 PaTu 8988t C156(1.32)  LDD1319  [3]
 LDCM0441  CL50 HEK-293T C156(0.83)  LDD1039  [3]
 LDCM0442  CL51 HEK-293T C156(0.84)  LDD1040  [3]
 LDCM0443  CL52 HEK-293T C156(1.07)  LDD1041  [3]
 LDCM0444  CL53 HEK-293T C156(1.10)  LDD1042  [3]
 LDCM0445  CL54 HEK-293T C156(0.77)  LDD1043  [3]
 LDCM0446  CL55 HEK-293T C156(0.91)  LDD1044  [3]
 LDCM0447  CL56 HEK-293T C156(0.87)  LDD1045  [3]
 LDCM0448  CL57 HEK-293T C156(0.85)  LDD1046  [3]
 LDCM0449  CL58 HEK-293T C156(0.90)  LDD1047  [3]
 LDCM0450  CL59 HEK-293T C156(0.96)  LDD1048  [3]
 LDCM0451  CL6 PaTu 8988t C156(1.17)  LDD1330  [3]
 LDCM0452  CL60 HEK-293T C156(0.89)  LDD1050  [3]
 LDCM0453  CL61 HEK-293T C156(1.03)  LDD1656  [6]
 LDCM0454  CL62 HEK-293T C156(0.98)  LDD1657  [6]
 LDCM0455  CL63 HEK-293T C156(1.02)  LDD1658  [6]
 LDCM0456  CL64 HEK-293T C156(1.48)  LDD1659  [6]
 LDCM0457  CL65 HEK-293T C156(0.92)  LDD1660  [6]
 LDCM0458  CL66 HEK-293T C156(1.05)  LDD1661  [6]
 LDCM0459  CL67 HEK-293T C156(1.07)  LDD1662  [6]
 LDCM0460  CL68 HEK-293T C156(1.20)  LDD1663  [6]
 LDCM0461  CL69 HEK-293T C156(1.35)  LDD1664  [6]
 LDCM0462  CL7 PaTu 8988t C156(1.18)  LDD1341  [3]
 LDCM0463  CL70 HEK-293T C156(1.22)  LDD1666  [6]
 LDCM0464  CL71 HEK-293T C156(1.23)  LDD1667  [6]
 LDCM0465  CL72 HEK-293T C156(1.14)  LDD1668  [6]
 LDCM0466  CL73 HEK-293T C156(1.23)  LDD1669  [6]
 LDCM0467  CL74 HEK-293T C156(0.91)  LDD1670  [6]
 LDCM0469  CL76 HEK-293T C156(0.92)  LDD1672  [6]
 LDCM0470  CL77 HEK-293T C156(1.35)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C156(0.91)  LDD1674  [6]
 LDCM0472  CL79 HEK-293T C156(1.07)  LDD1675  [6]
 LDCM0473  CL8 PaTu 8988t C156(1.44)  LDD1352  [3]
 LDCM0474  CL80 HEK-293T C156(1.03)  LDD1677  [6]
 LDCM0475  CL81 HEK-293T C156(1.13)  LDD1678  [6]
 LDCM0476  CL82 HEK-293T C156(1.07)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C156(1.32)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C156(1.52)  LDD1681  [6]
 LDCM0479  CL85 HEK-293T C156(1.23)  LDD1682  [6]
 LDCM0480  CL86 HEK-293T C156(1.18)  LDD1683  [6]
 LDCM0481  CL87 HEK-293T C156(1.14)  LDD1684  [6]
 LDCM0482  CL88 HEK-293T C156(1.01)  LDD1685  [6]
 LDCM0483  CL89 HEK-293T C156(1.22)  LDD1686  [6]
 LDCM0484  CL9 PaTu 8988t C156(1.09)  LDD1363  [3]
 LDCM0485  CL90 HEK-293T C156(1.45)  LDD1688  [6]
 LDCM0486  CL91 HEK-293T C156(1.15)  LDD1689  [6]
 LDCM0487  CL92 HEK-293T C156(1.21)  LDD1690  [6]
 LDCM0488  CL93 HEK-293T C156(1.45)  LDD1691  [6]
 LDCM0489  CL94 HEK-293T C156(1.15)  LDD1692  [6]
 LDCM0490  CL95 HEK-293T C156(2.30)  LDD1693  [6]
 LDCM0491  CL96 HEK-293T C156(1.87)  LDD1694  [6]
 LDCM0492  CL97 HEK-293T C156(1.51)  LDD1695  [6]
 LDCM0493  CL98 HEK-293T C156(1.10)  LDD1696  [6]
 LDCM0494  CL99 HEK-293T C156(1.01)  LDD1697  [6]
 LDCM0495  E2913 HEK-293T C156(1.03)  LDD1698  [6]
 LDCM0468  Fragment33 HEK-293T C156(0.97)  LDD1671  [6]
 LDCM0427  Fragment51 PaTu 8988t C156(1.33)  LDD1306  [3]
 LDCM0022  KB02 HEK-293T C156(0.79)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C156(0.94)  LDD1497  [6]
 LDCM0024  KB05 HEK-293T C156(0.79)  LDD1502  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
60 kDa lysophospholipase (ASPG) Asparaginase 1 family Q86U10
NADH-cytochrome b5 reductase 3 (CYB5R3) Flavoprotein pyridine nucleotide cytochrome reductase family P00387
TLC domain-containing protein 4 (TLCD4) TLCD4 family Q96MV1
Transporter and channel
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Endophilin-B1 (SH3GLB1) Endophilin family Q9Y371
Huntingtin (HTT) Huntingtin family P42858
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
Prenylated Rab acceptor protein 1 (RABAC1) PRA1 family Q9UI14
Thioredoxin-related transmembrane protein 2 (TMX2) . Q9Y320
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Nesprin-4 (SYNE4) Nesprin family Q8N205
Protein MANBAL (MANBAL) UPF0239 family Q9NQG1
Protein TMED8 (TMED8) . Q6PL24

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
5 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402