Details of the Target

General Information of Target

Target ID LDTP04681
Target Name Protein AF-17 (MLLT6)
Gene Name MLLT6
Gene ID 4302
Synonyms
AF17; Protein AF-17; ALL1-fused gene from chromosome 17 protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA
ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC
YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH
FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK
SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKG
KKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPK
LEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRAR
APSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGR
PKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPS
LSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTL
PSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRG
TSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIV
EMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYG
LPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLL
QQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLL
GGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLT
PEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPP
LLPAGALVAPSLGNNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGG
TADKGASANQEKG
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Uniprot ID
P55198
Ensemble ID
ENST00000618876.2
HGNC ID
HGNC:7138

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K731(10.00)  LDD0277  [1]
DBIA
 Probe Info  		C65(1.74); C68(1.74)  LDD0080  [2]
IA-alkyne
 Probe Info  		C137(0.00); C54(0.00)  LDD0166  [3]
TFBX
 Probe Info  		N.A.  LDD0027  [4]
IPM
 Probe Info  		N.A.  LDD2156  [5]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C65(1.11); C68(1.11)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C65(0.92); C68(0.92)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C65(0.72); C68(0.72)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C65(0.73); C68(0.73)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C65(0.77); C68(0.77)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C65(0.74); C68(0.74)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C65(0.74); C68(0.74)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C65(0.69); C68(0.69)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C65(0.91); C68(0.91)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C65(0.79); C68(0.79)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C65(0.71); C68(0.71)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C65(0.71); C68(0.71)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C65(0.99); C68(0.99)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C65(0.64); C68(0.64)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C65(0.68); C68(0.68)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C65(0.67); C68(0.67)  LDD0546  [2]
 LDCM0230  AC113 PaTu 8988t C65(0.95); C68(0.95)  LDD1109  [2]
 LDCM0231  AC114 PaTu 8988t C65(1.09); C68(1.09)  LDD1110  [2]
 LDCM0232  AC115 PaTu 8988t C65(0.90); C68(0.90)  LDD1111  [2]
 LDCM0233  AC116 PaTu 8988t C65(1.15); C68(1.15)  LDD1112  [2]
 LDCM0234  AC117 PaTu 8988t C65(0.98); C68(0.98)  LDD1113  [2]
 LDCM0235  AC118 PaTu 8988t C65(1.10); C68(1.10)  LDD1114  [2]
 LDCM0236  AC119 PaTu 8988t C65(0.95); C68(0.95)  LDD1115  [2]
 LDCM0237  AC12 HCT 116 C65(0.98); C68(0.98)  LDD0554  [2]
 LDCM0238  AC120 PaTu 8988t C65(1.01); C68(1.01)  LDD1117  [2]
 LDCM0239  AC121 PaTu 8988t C65(0.95); C68(0.95)  LDD1118  [2]
 LDCM0240  AC122 PaTu 8988t C65(0.87); C68(0.87)  LDD1119  [2]
 LDCM0241  AC123 PaTu 8988t C65(0.85); C68(0.85)  LDD1120  [2]
 LDCM0242  AC124 PaTu 8988t C65(0.98); C68(0.98)  LDD1121  [2]
 LDCM0243  AC125 PaTu 8988t C65(0.99); C68(0.99)  LDD1122  [2]
 LDCM0244  AC126 PaTu 8988t C65(0.95); C68(0.95)  LDD1123  [2]
 LDCM0245  AC127 PaTu 8988t C65(0.91); C68(0.91)  LDD1124  [2]
 LDCM0246  AC128 HCT 116 C65(0.98); C68(0.98)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C65(0.83); C68(0.83)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C65(0.89); C68(0.89)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C65(1.00); C68(1.00)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C65(0.81); C68(0.81)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C65(0.94); C68(0.94)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C65(1.02); C68(1.02)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C65(0.95); C68(0.95)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C65(0.95); C68(0.95)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C65(0.95); C68(0.95)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C65(0.92); C68(0.92)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C65(1.11); C68(1.11)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C65(1.00); C68(1.00)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C65(0.93); C68(0.93)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C65(0.88); C68(0.88)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C65(0.99); C68(0.99)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C65(0.95); C68(0.95)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C65(0.92); C68(0.92)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C65(1.01); C68(1.01)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C65(1.03); C68(1.03)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C65(0.96); C68(0.96)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C65(1.03); C68(1.03)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C65(1.04); C68(1.04)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C65(1.03); C68(1.03)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C65(0.95); C68(0.95)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C65(1.05); C68(1.05)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C65(0.99); C68(0.99)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C65(1.04); C68(1.04)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C65(0.94); C68(0.94)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C65(1.00); C68(1.00)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C65(0.91); C68(0.91)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C65(0.88); C68(0.88)  LDD2161  [2]
 LDCM0276  AC17 PaTu 8988t C65(0.94); C68(0.94)  LDD1155  [2]
 LDCM0277  AC18 PaTu 8988t C65(1.17); C68(1.17)  LDD1156  [2]
 LDCM0278  AC19 PaTu 8988t C65(0.92); C68(0.92)  LDD1157  [2]
 LDCM0279  AC2 HCT 116 C65(0.96); C68(0.96)  LDD0596  [2]
 LDCM0280  AC20 PaTu 8988t C65(0.98); C68(0.98)  LDD1159  [2]
 LDCM0281  AC21 PaTu 8988t C65(1.03); C68(1.03)  LDD1160  [2]
 LDCM0282  AC22 PaTu 8988t C65(0.93); C68(0.93)  LDD1161  [2]
 LDCM0283  AC23 PaTu 8988t C65(1.06); C68(1.06)  LDD1162  [2]
 LDCM0284  AC24 PaTu 8988t C65(1.22); C68(1.22)  LDD1163  [2]
 LDCM0290  AC3 HCT 116 C65(0.98); C68(0.98)  LDD0607  [2]
 LDCM0296  AC35 PaTu 8988t C65(1.06); C68(1.06)  LDD1175  [2]
 LDCM0297  AC36 PaTu 8988t C65(1.06); C68(1.06)  LDD1176  [2]
 LDCM0298  AC37 PaTu 8988t C65(0.97); C68(0.97)  LDD1177  [2]
 LDCM0299  AC38 PaTu 8988t C65(0.99); C68(0.99)  LDD1178  [2]
 LDCM0300  AC39 PaTu 8988t C65(1.07); C68(1.07)  LDD1179  [2]
 LDCM0301  AC4 HCT 116 C65(1.03); C68(1.03)  LDD0618  [2]
 LDCM0302  AC40 PaTu 8988t C65(1.08); C68(1.08)  LDD1181  [2]
 LDCM0303  AC41 PaTu 8988t C65(1.03); C68(1.03)  LDD1182  [2]
 LDCM0304  AC42 PaTu 8988t C65(1.01); C68(1.01)  LDD1183  [2]
 LDCM0305  AC43 PaTu 8988t C65(1.01); C68(1.01)  LDD1184  [2]
 LDCM0306  AC44 PaTu 8988t C65(0.95); C68(0.95)  LDD1185  [2]
 LDCM0307  AC45 PaTu 8988t C65(1.02); C68(1.02)  LDD1186  [2]
 LDCM0308  AC46 PaTu 8988t C65(0.87); C68(0.87)  LDD1187  [2]
 LDCM0309  AC47 PaTu 8988t C65(0.90); C68(0.90)  LDD1188  [2]
 LDCM0310  AC48 PaTu 8988t C65(0.90); C68(0.90)  LDD1189  [2]
 LDCM0311  AC49 PaTu 8988t C65(1.01); C68(1.01)  LDD1190  [2]
 LDCM0312  AC5 HCT 116 C65(1.00); C68(1.00)  LDD0629  [2]
 LDCM0313  AC50 PaTu 8988t C65(1.04); C68(1.04)  LDD1192  [2]
 LDCM0314  AC51 PaTu 8988t C65(0.21); C68(0.21)  LDD1193  [2]
 LDCM0315  AC52 PaTu 8988t C65(0.88); C68(0.88)  LDD1194  [2]
 LDCM0316  AC53 PaTu 8988t C65(1.05); C68(1.05)  LDD1195  [2]
 LDCM0317  AC54 PaTu 8988t C65(1.05); C68(1.05)  LDD1196  [2]
 LDCM0318  AC55 PaTu 8988t C65(1.25); C68(1.25)  LDD1197  [2]
 LDCM0319  AC56 PaTu 8988t C65(0.91); C68(0.91)  LDD1198  [2]
 LDCM0320  AC57 HCT 116 C65(0.98); C68(0.98)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C65(0.85); C68(0.85)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C65(0.88); C68(0.88)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C65(0.96); C68(0.96)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C65(1.15); C68(1.15)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C65(0.94); C68(0.94)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C65(0.91); C68(0.91)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C65(0.88); C68(0.88)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C65(0.93); C68(0.93)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C65(0.94); C68(0.94)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C65(0.97); C68(0.97)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C65(0.71); C68(0.71)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C65(1.18); C68(1.18)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C65(0.95); C68(0.95)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C65(1.02); C68(1.02)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C65(0.95); C68(0.95)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C65(1.04); C68(1.04)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C65(0.93); C68(0.93)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C65(0.89); C68(0.89)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C65(0.95); C68(0.95)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C65(0.81); C68(0.81)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C65(1.10); C68(1.10)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C65(1.04); C68(1.04)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C65(0.91); C68(0.91)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C65(0.97); C68(0.97)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C65(0.98); C68(0.98)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C65(0.84); C68(0.84)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C65(1.34); C68(1.34)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C65(0.67); C68(0.67)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C65(0.85); C68(0.85)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C65(0.89); C68(0.89)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C65(0.81); C68(0.81)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C65(0.83); C68(0.83)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C65(0.82); C68(0.82)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C65(0.84); C68(0.84)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C65(0.91); C68(0.91)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C65(0.88); C68(0.88)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C65(0.86); C68(0.86)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C65(0.88); C68(0.88)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C65(0.83); C68(0.83)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C65(0.77); C68(0.77)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C65(1.18); C68(1.18)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C65(0.79); C68(0.79)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C65(0.76); C68(0.76)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C65(0.60); C68(0.60)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C65(0.66); C68(0.66)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C65(0.86); C68(0.86)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C65(1.03); C68(1.03)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C65(1.09); C68(1.09)  LDD0592  [2]
 LDCM0367  CL1 PaTu 8988t C65(0.97); C68(0.97)  LDD1246  [2]
 LDCM0368  CL10 PaTu 8988t C65(0.78); C68(0.78)  LDD1247  [2]
 LDCM0369  CL100 HCT 116 C65(0.93); C68(0.93)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C65(1.06); C68(1.06)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C65(1.05); C68(1.05)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C65(0.97); C68(0.97)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C65(0.99); C68(0.99)  LDD0690  [2]
 LDCM0374  CL105 PaTu 8988t C65(1.01); C68(1.01)  LDD1253  [2]
 LDCM0375  CL106 PaTu 8988t C65(1.02); C68(1.02)  LDD1254  [2]
 LDCM0376  CL107 PaTu 8988t C65(1.01); C68(1.01)  LDD1255  [2]
 LDCM0377  CL108 PaTu 8988t C65(1.10); C68(1.10)  LDD1256  [2]
 LDCM0378  CL109 PaTu 8988t C65(0.95); C68(0.95)  LDD1257  [2]
 LDCM0379  CL11 PaTu 8988t C65(0.85); C68(0.85)  LDD1258  [2]
 LDCM0380  CL110 PaTu 8988t C65(1.25); C68(1.25)  LDD1259  [2]
 LDCM0381  CL111 PaTu 8988t C65(1.16); C68(1.16)  LDD1260  [2]
 LDCM0387  CL117 PaTu 8988t C65(0.97); C68(0.97)  LDD1266  [2]
 LDCM0388  CL118 PaTu 8988t C65(1.13); C68(1.13)  LDD1267  [2]
 LDCM0389  CL119 PaTu 8988t C65(1.03); C68(1.03)  LDD1268  [2]
 LDCM0390  CL12 PaTu 8988t C65(0.85); C68(0.85)  LDD1269  [2]
 LDCM0391  CL120 PaTu 8988t C65(0.99); C68(0.99)  LDD1270  [2]
 LDCM0392  CL121 PaTu 8988t C65(0.90); C68(0.90)  LDD1271  [2]
 LDCM0393  CL122 PaTu 8988t C65(0.90); C68(0.90)  LDD1272  [2]
 LDCM0394  CL123 PaTu 8988t C65(0.87); C68(0.87)  LDD1273  [2]
 LDCM0395  CL124 PaTu 8988t C65(0.76); C68(0.76)  LDD1274  [2]
 LDCM0396  CL125 HCT 116 C65(0.80); C68(0.80)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C65(0.94); C68(0.94)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C65(0.78); C68(0.78)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C65(1.19); C68(1.19)  LDD0716  [2]
 LDCM0400  CL13 PaTu 8988t C65(0.95); C68(0.95)  LDD1279  [2]
 LDCM0401  CL14 PaTu 8988t C65(0.98); C68(0.98)  LDD1280  [2]
 LDCM0402  CL15 PaTu 8988t C65(0.73); C68(0.73)  LDD1281  [2]
 LDCM0403  CL16 HCT 116 C65(1.32); C68(1.32)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C65(1.09); C68(1.09)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C65(1.73); C68(1.73)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C65(1.18); C68(1.18)  LDD0723  [2]
 LDCM0407  CL2 PaTu 8988t C65(0.90); C68(0.90)  LDD1286  [2]
 LDCM0408  CL20 HCT 116 C65(1.15); C68(1.15)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C65(0.99); C68(0.99)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C65(1.60); C68(1.60)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C65(1.36); C68(1.36)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C65(1.22); C68(1.22)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C65(1.33); C68(1.33)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C65(1.27); C68(1.27)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C65(1.34); C68(1.34)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C65(1.17); C68(1.17)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C65(1.32); C68(1.32)  LDD0734  [2]
 LDCM0418  CL3 PaTu 8988t C65(1.05); C68(1.05)  LDD1297  [2]
 LDCM0419  CL30 HCT 116 C65(1.29); C68(1.29)  LDD0736  [2]
 LDCM0420  CL31 PaTu 8988t C65(1.02); C68(1.02)  LDD1299  [2]
 LDCM0421  CL32 PaTu 8988t C65(1.11); C68(1.11)  LDD1300  [2]
 LDCM0422  CL33 PaTu 8988t C65(0.75); C68(0.75)  LDD1301  [2]
 LDCM0423  CL34 PaTu 8988t C65(1.11); C68(1.11)  LDD1302  [2]
 LDCM0424  CL35 PaTu 8988t C65(1.23); C68(1.23)  LDD1303  [2]
 LDCM0425  CL36 PaTu 8988t C65(0.22); C68(0.22)  LDD1304  [2]
 LDCM0426  CL37 PaTu 8988t C65(1.28); C68(1.28)  LDD1305  [2]
 LDCM0428  CL39 PaTu 8988t C65(0.96); C68(0.96)  LDD1307  [2]
 LDCM0429  CL4 PaTu 8988t C65(0.90); C68(0.90)  LDD1308  [2]
 LDCM0430  CL40 PaTu 8988t C65(1.11); C68(1.11)  LDD1309  [2]
 LDCM0431  CL41 PaTu 8988t C65(0.93); C68(0.93)  LDD1310  [2]
 LDCM0432  CL42 PaTu 8988t C65(1.15); C68(1.15)  LDD1311  [2]
 LDCM0433  CL43 PaTu 8988t C65(1.11); C68(1.11)  LDD1312  [2]
 LDCM0434  CL44 PaTu 8988t C65(1.20); C68(1.20)  LDD1313  [2]
 LDCM0435  CL45 PaTu 8988t C65(0.98); C68(0.98)  LDD1314  [2]
 LDCM0436  CL46 HCT 116 C65(1.16); C68(1.16)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C65(0.92); C68(0.92)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C65(1.04); C68(1.04)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C65(0.89); C68(0.89)  LDD0756  [2]
 LDCM0440  CL5 PaTu 8988t C65(1.26); C68(1.26)  LDD1319  [2]
 LDCM0441  CL50 HCT 116 C65(1.01); C68(1.01)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C65(1.05); C68(1.05)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C65(1.11); C68(1.11)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C65(0.97); C68(0.97)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C65(1.16); C68(1.16)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C65(1.18); C68(1.18)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C65(0.98); C68(0.98)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C65(1.03); C68(1.03)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C65(1.00); C68(1.00)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C65(1.03); C68(1.03)  LDD0767  [2]
 LDCM0451  CL6 PaTu 8988t C65(1.05); C68(1.05)  LDD1330  [2]
 LDCM0452  CL60 HCT 116 C65(0.84); C68(0.84)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C65(0.90); C68(0.90)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C65(0.88); C68(0.88)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C65(0.94); C68(0.94)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C65(0.93); C68(0.93)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C65(0.84); C68(0.84)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C65(0.87); C68(0.87)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C65(0.90); C68(0.90)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C65(0.94); C68(0.94)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C65(1.18); C68(1.18)  LDD0778  [2]
 LDCM0462  CL7 PaTu 8988t C65(1.04); C68(1.04)  LDD1341  [2]
 LDCM0463  CL70 HCT 116 C65(0.96); C68(0.96)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C65(0.84); C68(0.84)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C65(0.88); C68(0.88)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C65(0.80); C68(0.80)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C65(0.90); C68(0.90)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C65(1.22); C68(1.22)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C65(0.98); C68(0.98)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C65(0.97); C68(0.97)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C65(1.00); C68(1.00)  LDD0789  [2]
 LDCM0473  CL8 PaTu 8988t C65(0.63); C68(0.63)  LDD1352  [2]
 LDCM0474  CL80 HCT 116 C65(1.12); C68(1.12)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C65(1.04); C68(1.04)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C65(1.14); C68(1.14)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C65(1.06); C68(1.06)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C65(1.05); C68(1.05)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C65(1.06); C68(1.06)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C65(0.94); C68(0.94)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C65(1.04); C68(1.04)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C65(1.14); C68(1.14)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C65(1.15); C68(1.15)  LDD0800  [2]
 LDCM0484  CL9 PaTu 8988t C65(0.84); C68(0.84)  LDD1363  [2]
 LDCM0485  CL90 HCT 116 C65(0.73); C68(0.73)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C65(1.05); C68(1.05)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C65(0.86); C68(0.86)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C65(1.15); C68(1.15)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C65(0.99); C68(0.99)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C65(0.88); C68(0.88)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C65(1.06); C68(1.06)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C65(0.96); C68(0.96)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C65(0.93); C68(0.93)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C65(1.13); C68(1.13)  LDD0811  [2]
 LDCM0468  Fragment33 HCT 116 C65(0.95); C68(0.95)  LDD0785  [2]
 LDCM0427  Fragment51 PaTu 8988t C65(1.06); C68(1.06)  LDD1306  [2]
 LDCM0022  KB02 HCT 116 C65(1.74); C68(1.74)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C65(2.69); C68(2.69)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C65(1.66); C68(1.66)  LDD0082  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) . Q13526
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ubiquilin-4 (UBQLN4) . Q9NRR5
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-10 (ATXN10) Ataxin-10 family Q9UBB4
GRIP1-associated protein 1 (GRIPAP1) . Q4V328
Zinc finger MYND domain-containing protein 19 (ZMYND19) . Q96E35

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
6 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004