Details of the Target

General Information of Target

Target ID LDTP03744
Target Name Thrombospondin-4 (THBS4)
Gene Name THBS4
Gene ID 7060
Synonyms
TSP4; Thrombospondin-4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV
ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA
DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ
DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL
LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ
CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP
MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA
ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR
NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG
DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD
ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG
DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP
ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD
FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK
SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE
GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD
N
Target Bioclass
Other
Family
Thrombospondin family
Subcellular location
Endoplasmic reticulum
Function
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
Uniprot ID
P35443
Ensemble ID
ENST00000350881.6
HGNC ID
HGNC:11788

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C461(1.31)  LDD0547  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C461(0.98); C925(0.98)  LDD0812  [1]
 LDCM0215  AC10 PaTu 8988t C461(1.26)  LDD1094  [1]
 LDCM0216  AC100 HEK-293T C461(0.82); C925(0.82)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C461(1.05); C925(1.05)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C461(0.70); C925(0.70)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C461(0.79); C925(0.79)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C461(0.80); C925(0.80)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C461(0.83); C925(0.83)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C461(0.87); C925(0.87)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C461(0.83); C925(0.83)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C461(0.89); C925(0.89)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C461(0.94); C925(0.94)  LDD0823  [1]
 LDCM0226  AC11 PaTu 8988t C461(1.00)  LDD1105  [1]
 LDCM0227  AC110 HEK-293T C461(0.97); C925(0.97)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C461(0.90); C925(0.90)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C461(0.83); C925(0.83)  LDD0827  [1]
 LDCM0230  AC113 HCT 116 C461(1.31)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C461(0.96)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C461(1.44)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C461(1.88)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C461(1.44)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C461(1.25)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C461(1.23)  LDD0553  [1]
 LDCM0237  AC12 PaTu 8988t C461(0.92)  LDD1116  [1]
 LDCM0238  AC120 HCT 116 C461(0.97)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C461(0.73)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C461(1.26)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C461(0.60)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C461(1.10)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C461(1.22)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C461(1.05)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C461(1.04)  LDD0562  [1]
 LDCM0246  AC128 HEK-293T C461(0.68); C925(0.68)  LDD0844  [1]
 LDCM0247  AC129 HEK-293T C461(0.77); C925(0.77)  LDD0845  [1]
 LDCM0249  AC130 HEK-293T C461(0.67); C925(0.67)  LDD0847  [1]
 LDCM0250  AC131 HEK-293T C461(0.70); C925(0.70)  LDD0848  [1]
 LDCM0251  AC132 HEK-293T C461(0.73); C925(0.73)  LDD0849  [1]
 LDCM0252  AC133 HEK-293T C461(0.72); C925(0.72)  LDD0850  [1]
 LDCM0253  AC134 HEK-293T C461(0.63); C925(0.63)  LDD0851  [1]
 LDCM0254  AC135 HEK-293T C461(0.66); C925(0.66)  LDD0852  [1]
 LDCM0255  AC136 HEK-293T C461(0.57); C925(0.57)  LDD0853  [1]
 LDCM0256  AC137 HEK-293T C461(0.69); C925(0.69)  LDD0854  [1]
 LDCM0257  AC138 HEK-293T C461(0.61); C925(0.61)  LDD0855  [1]
 LDCM0258  AC139 HEK-293T C461(0.70); C925(0.70)  LDD0856  [1]
 LDCM0259  AC14 PaTu 8988t C461(0.93)  LDD1138  [1]
 LDCM0260  AC140 HEK-293T C461(0.74); C925(0.74)  LDD0858  [1]
 LDCM0261  AC141 HEK-293T C461(0.66); C925(0.66)  LDD0859  [1]
 LDCM0262  AC142 HEK-293T C461(0.65); C925(0.65)  LDD0860  [1]
 LDCM0270  AC15 PaTu 8988t C461(1.29)  LDD1149  [1]
 LDCM0276  AC17 HCT 116 C477(1.70)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C477(0.60)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C477(0.56)  LDD0595  [1]
 LDCM0279  AC2 HEK-293T C461(0.81); C925(0.81)  LDD0877  [1]
 LDCM0280  AC20 HCT 116 C477(0.91)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C477(0.76)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C477(1.04)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C477(0.86)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C477(0.93)  LDD0601  [1]
 LDCM0285  AC25 HEK-293T C461(0.98); C925(0.91)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C461(1.07); C925(0.93)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C461(1.10); C925(0.92)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C461(1.10); C925(1.12)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C461(1.06); C925(0.82)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C461(0.96); C925(0.96)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C461(1.08); C925(0.93)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C461(0.98); C925(1.01)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C461(1.10); C925(1.09)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C461(1.08); C925(0.88)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C461(1.15); C925(1.15)  LDD0893  [1]
 LDCM0296  AC35 HCT 116 C461(0.27)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C461(0.39)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C461(0.28)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C461(0.47)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C461(0.36)  LDD0617  [1]
 LDCM0301  AC4 HEK-293T C461(1.20); C925(1.20)  LDD0899  [1]
 LDCM0302  AC40 HCT 116 C461(0.26)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C461(0.57)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C461(0.52)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C461(0.61)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C461(0.44)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C461(0.42)  LDD0624  [1]
 LDCM0308  AC46 HCT 116 C477(0.96)  LDD0625  [1]
 LDCM0309  AC47 HCT 116 C477(0.85)  LDD0626  [1]
 LDCM0310  AC48 HCT 116 C477(1.05)  LDD0627  [1]
 LDCM0311  AC49 HCT 116 C477(0.91)  LDD0628  [1]
 LDCM0312  AC5 HEK-293T C461(1.05); C925(1.05)  LDD0910  [1]
 LDCM0313  AC50 HCT 116 C477(0.79)  LDD0630  [1]
 LDCM0314  AC51 HCT 116 C477(0.68)  LDD0631  [1]
 LDCM0315  AC52 HCT 116 C477(0.81)  LDD0632  [1]
 LDCM0316  AC53 HCT 116 C477(0.69)  LDD0633  [1]
 LDCM0317  AC54 HCT 116 C477(0.71)  LDD0634  [1]
 LDCM0318  AC55 HCT 116 C477(1.33)  LDD0635  [1]
 LDCM0319  AC56 HCT 116 C477(0.68)  LDD0636  [1]
 LDCM0323  AC6 PaTu 8988t C461(0.94)  LDD1202  [1]
 LDCM0332  AC68 HCT 116 C477(0.94)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C477(0.93)  LDD0650  [1]
 LDCM0334  AC7 PaTu 8988t C461(1.32)  LDD1213  [1]
 LDCM0335  AC70 HCT 116 C477(1.01)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C477(1.11)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C477(1.21)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C477(1.15)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C477(0.99)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C477(0.92)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C477(1.11)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C477(0.86)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C477(1.15)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C477(0.91)  LDD0661  [1]
 LDCM0345  AC8 PaTu 8988t C461(1.01)  LDD1224  [1]
 LDCM0346  AC80 HCT 116 C477(0.95)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C477(1.15)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C477(1.05)  LDD0665  [1]
 LDCM0349  AC83 HEK-293T C461(0.81)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C461(1.42)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C461(0.86)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C461(0.73)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C461(1.02)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C461(0.77)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C461(0.99)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C461(1.01)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C461(0.92)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C461(0.82)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C461(0.97)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C461(1.18)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C461(0.90)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C461(0.81)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C461(0.72)  LDD0962  [1]
 LDCM0365  AC98 HEK-293T C461(1.00); C925(1.00)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C461(0.80); C925(0.80)  LDD0964  [1]
 LDCM0248  AKOS034007472 PaTu 8988t C461(0.84)  LDD1127  [1]
 LDCM0356  AKOS034007680 PaTu 8988t C461(1.27)  LDD1235  [1]
 LDCM0275  AKOS034007705 PaTu 8988t C461(1.34)  LDD1154  [1]
 LDCM0367  CL1 HCT 116 C461(0.82)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C461(0.73)  LDD0685  [1]
 LDCM0369  CL100 HEK-293T C461(0.89); C925(0.89)  LDD0967  [1]
 LDCM0370  CL101 PaTu 8988t C461(1.01)  LDD1249  [1]
 LDCM0371  CL102 PaTu 8988t C461(1.03)  LDD1250  [1]
 LDCM0372  CL103 PaTu 8988t C461(1.11)  LDD1251  [1]
 LDCM0373  CL104 PaTu 8988t C461(0.72)  LDD1252  [1]
 LDCM0374  CL105 HCT 116 C477(1.55)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C477(1.20)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C477(1.19)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C477(1.60)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C477(0.78)  LDD0695  [1]
 LDCM0379  CL11 HCT 116 C461(0.66)  LDD0696  [1]
 LDCM0380  CL110 HCT 116 C477(0.89)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C477(1.05)  LDD0698  [1]
 LDCM0382  CL112 HEK-293T C461(0.89); C925(1.03)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C461(1.02); C925(0.83)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C461(0.88); C925(0.88)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C461(0.93); C925(0.84)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C461(0.99); C925(0.86)  LDD0984  [1]
 LDCM0387  CL117 HCT 116 C461(0.21)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C461(0.48)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C461(0.37)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C461(0.49)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C461(0.41)  LDD0708  [1]
 LDCM0392  CL121 HCT 116 C477(1.23)  LDD0709  [1]
 LDCM0393  CL122 HCT 116 C477(0.84)  LDD0710  [1]
 LDCM0394  CL123 HCT 116 C477(0.79)  LDD0711  [1]
 LDCM0395  CL124 HCT 116 C477(0.71)  LDD0712  [1]
 LDCM0400  CL13 HCT 116 C461(0.87)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C461(0.66)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C461(0.73)  LDD0719  [1]
 LDCM0403  CL16 HCT 116 C477(1.04)  LDD0720  [1]
 LDCM0407  CL2 HCT 116 C461(0.62)  LDD0724  [1]
 LDCM0418  CL3 HCT 116 C461(0.66)  LDD0735  [1]
 LDCM0420  CL31 HEK-293T C461(1.05); C925(1.05)  LDD1018  [1]
 LDCM0421  CL32 HCT 116 C477(1.35)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C477(0.93)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C477(1.37)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C477(1.99)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C477(1.39)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C477(1.78)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C477(1.04)  LDD0745  [1]
 LDCM0429  CL4 HCT 116 C461(0.73)  LDD0746  [1]
 LDCM0430  CL40 HCT 116 C477(1.35)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C477(1.34)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C477(0.99)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C477(1.51)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C477(2.26)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C477(1.79)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C461(1.14)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C461(1.17)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C461(1.14)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C461(1.09)  LDD0756  [1]
 LDCM0440  CL5 HCT 116 C461(0.77)  LDD0757  [1]
 LDCM0441  CL50 HCT 116 C461(0.83)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C461(1.04)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C461(1.02)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C461(0.95)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C461(0.93)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C461(1.03)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C461(1.06)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C461(1.04)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C461(0.98)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C461(1.03)  LDD0767  [1]
 LDCM0451  CL6 HCT 116 C461(0.82)  LDD0768  [1]
 LDCM0452  CL60 HCT 116 C461(1.15)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C477(1.10)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C477(1.09)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C477(1.12)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C477(1.04)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C477(1.19)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C477(1.18)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C477(1.09)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C477(0.82)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C477(0.73)  LDD0778  [1]
 LDCM0462  CL7 HCT 116 C461(0.79)  LDD0779  [1]
 LDCM0463  CL70 HCT 116 C477(0.78)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C477(0.77)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C477(0.75)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C477(0.79)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C477(0.85)  LDD0784  [1]
 LDCM0469  CL76 PaTu 8988t C461(1.48)  LDD1348  [1]
 LDCM0470  CL77 PaTu 8988t C461(1.08)  LDD1349  [1]
 LDCM0471  CL78 PaTu 8988t C461(1.41)  LDD1350  [1]
 LDCM0472  CL79 PaTu 8988t C461(2.18)  LDD1351  [1]
 LDCM0473  CL8 HCT 116 C461(1.04)  LDD0790  [1]
 LDCM0474  CL80 PaTu 8988t C461(1.22)  LDD1353  [1]
 LDCM0475  CL81 PaTu 8988t C461(1.93)  LDD1354  [1]
 LDCM0476  CL82 PaTu 8988t C461(1.38)  LDD1355  [1]
 LDCM0477  CL83 PaTu 8988t C461(2.34)  LDD1356  [1]
 LDCM0478  CL84 PaTu 8988t C461(1.80)  LDD1357  [1]
 LDCM0479  CL85 PaTu 8988t C461(0.94)  LDD1358  [1]
 LDCM0480  CL86 PaTu 8988t C461(1.70)  LDD1359  [1]
 LDCM0481  CL87 PaTu 8988t C461(1.29)  LDD1360  [1]
 LDCM0482  CL88 PaTu 8988t C461(1.81)  LDD1361  [1]
 LDCM0483  CL89 PaTu 8988t C461(1.54)  LDD1362  [1]
 LDCM0484  CL9 HCT 116 C461(0.76)  LDD0801  [1]
 LDCM0485  CL90 PaTu 8988t C461(2.03)  LDD1364  [1]
 LDCM0486  CL91 HEK-293T C461(1.44); C925(1.44)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C461(1.40); C925(1.40)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C461(0.99); C925(0.99)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C461(1.07); C925(1.07)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C461(0.97); C925(0.97)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C461(1.03); C925(1.03)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C461(1.09); C925(1.09)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C461(1.00); C925(1.00)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C461(0.97); C925(0.97)  LDD1092  [1]
 LDCM0468  Fragment33 HCT 116 C477(1.22)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C477(1.34)  LDD0744  [1]
 LDCM0022  KB02 COLO 320 C925(1.38)  LDD2303  [2]
 LDCM0023  KB03 A204 C925(1.57)  LDD2669  [2]
 LDCM0024  KB05 NCI-H146 C925(1.74)  LDD3344  [2]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840